Page last updated: 2024-08-23

benzonidazole and Acute Disease

benzonidazole has been researched along with Acute Disease in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (13.95)18.2507
2000's12 (27.91)29.6817
2010's18 (41.86)24.3611
2020's7 (16.28)2.80

Authors

AuthorsStudies
Boiani, L; Boiani, M; Cerecetto, H; Denicola, A; Gómez-Barrio, A; Gonzalez, M; Nakayama, H; Rojas de Arias, A; Rolan, M; Sanabria, L; Serna, E; Torres de Ortiz, S; Vega, C; Vera de Bilbao, N; Yaluff, G1
Bahia, MT; Carneiro, CM; Lana, M; Macedo, AM; Machado-Coelho, GL; Martins, HR; Martins-Filho, OA; Silva, RM; Toledo, MJ; Valadares, HM; Veloso, VM; Vitelli-Avelar, DM1
Arredondo, C; Basombrío, MA; Boiani, L; Boiani, M; Cerecetto, H; Davies, C; Gerpe, A; González, M; Merlino, A; Pacheco, JP; Porcal, W1
Faral-Tello, P; Mahler, G; Pizzo, C; Robello, C; Saiz, C; Serna, E; Torres, S; Vera, N; Yaluff, G1
Clares, MP; Delgado-Pinar, E; García-España, E; Marín, C; Martín-Escolano, J; Martín-Escolano, R; Martin-Montes, Á; Medina-Carmona, E; Molina-Carreño, D; Pitarch-Jarque, J; Rosales, MJ; Sánchez-Moreno, M1
Carneiro, CM; Carvalho, LM; Correa-Oliveira, R; de Carvalho, TV; Fonseca, KDS; Madeira, JV; Medeiros, LDF; Molina, I; Perin, L; Vieira, PMA1
Díaz, ML; Echeverría, LE; Eduardo Nieto, J; González, CI; Hernandez, JCM; López-Romero, LA; Morillo, CA; Ochoa, SAG; Rivera, JD; Rojas, LZ; Suárez, EU1
Cascabulho, CM; Castro, SL; Demarque, KC; Duque, TLA; Guimarães, ACR; Manso, PPA; Menna-Barreto, RF; Meuser-Batista, M; Moura, KCG; Oliveira, GM; Pelajo-Machado, M; Pinto, MDC1
Bermúdez, JM; Cid, AG; Davies, C; Micheloud, JF; Negrette, OS; Parada, LA; Ragone, PG; Simonazzi, A1
Búa, J; Esteva, MI; Fichera, LE; Rial, MS; Salomon, CJ; Seremeta, KP1
Cotta-de-Almeida, V; de Araújo-Jorge, TC; de Meis, J; Ferreira-Reis, R; Lannes-Vieira, J; Marins-Dos-Santos, A; Olivieri, BP; Silva, AA1
Bottari, NB; da Silva, AD; da Silva, AS; Fracasso, M; Monteiro, SG; Reichert, K; Schetinger, MRC1
Bahia, MT; Caldas, IS; Caldas, S; Diniz, LF; Menezes, APJ; Nascimento, ÁFDSD; Novaes, RD1
Bezerra, FS; Costa, GP; Figueiredo, VP; Horta, AL; Leite, ALJ; Menezes, APJ; Pedrosa, TCF; Ramos, CO; Talvani, A; Vieira, PMA1
Assy, JGPL; Berreta, OCP; Esper, HR; França, FOS; Freitas, VLT; Lopes, MH; Shimoda, EY1
Carneiro, CM; Cunha, ELA; Cunha, LM; de Lana, M; de Oliveira, MT; Fonseca, KDS; Torchelsen, FKVDS; Vieira, PMA1
Cunha, WR; da Silva Ferreira, D; de Albuquerque, S; do Prado Júnior, JC; e Silva, ML; Esperandim, VR; Kuehn, CC; Toldo, MP1
Coura, JR; de Macedo, RC; Ferreira, AG; Junqueira, AC; Pinto, AY; Santos, LC; Valente, SA; Valente, Vda C1
Díaz, ML; Escobar, P; González Rugeles, CI; Leal, S; López-Muñoz, R; Mantilla, JC; Molina-Berríos, A; Solari, A1
Caldas, IS; Gonçalves, RV; Novaes, RD; Rodrigues, JP; Santos, EC; Sartini, MV; Souza, RL1
Branquinho, RT; de Mello, CG; Lana, Md; Milagre, MM; Mosqueira, VC; Oliveira, MT; Saúde-Guimarães, DA1
Antunes, AF; Barbosa, Md; Ferreira, JM; Guerra, JA; Maduro, SG; Pereira, BV1
Bahia, MT; de Lana, M; dos Santos, DM; Guedes, PM; Machado-Coelho, GL; Talvani, A1
Albuquerque, S; do Prado, JC; Kuehn, CC; Loria, RM; Oliveira, LG; Santos, CD; Toldo, MP1
Corrêa, RR; Correia, D; dos Reis, MA; Faleiros, AC; Guimarães, CS; Oliveira, FA; Ramirez, LE; Silva, AC; Silva, AE; Teixeira, AC; Teixeira, Vde P1
Aras, R; Bastos, CJ; de Araújo, EG; de Jesus, RS; Dias, JP; Freire, MS; Grassi, MF; Mota, G; Prazeres, J; Reis, F1
Clayton, J1
Apt, W1
Ferreira, J; Kemmerling, U; López-Muñoz, R; Maya, JD; Morello, A; Orellana, M1
Basombrío, MA; Cardozo, R; Corrales, M; Segura, MA; Urbina, JA1
Araújo-Jorge, T; Cotta-de-Almeida, V; de Castro, SL; de Souza, AP; Olivieri, BP1
El Masri, M; Karcz, DA; Lennox, HA; Tales, H1
Bahia, MT; Caldas, IS; Caldas, S; Carneiro, CM; da Matta Guedes, PM; de Lana, M; Talvani, A1
Almiron, M; Campetella, O; Frasch, AC; Ganzález Cappa, SM; Guillen, I; Leguizamón, MS; Russomando, G1
Cancado, JR; Galvao, LM; Gazzinelli, RT; Krautz, G; Krettli, AU; Lima, PC; Scharfstein, J1
Añez, N; Carrasco, HA; Fuenmayor, C; Inglessis, I; Parada, H1
Brener, Z; Carvalho-Oliveira, L; Ferreira, LR; Gazzinelli, RT; Michailowsky, V; Murta, SM; Pereira, ME; Romanha, AJ1
Brener, Z; Loebenberg, D; Martins-Filho, O; Molina, J; Romanha, AJ; Urbina, JA1
Bonté, F; Ferreira, ME; Fournet, A; Lavault, M; Nakayama, H; Rojas de Arias, A; Samudio, M; Schinini, A; Torres de Ortiz, S; Vera de Bilbao, N1
Andrade, SG; Andrade, ZA; Lima, ES1
da Silva, JS; Souza, SC; Takahashi, CS1
Frasch, AC; Jazín, EE; Luquetti, AO; Rassi, A1

Reviews

3 review(s) available for benzonidazole and Acute Disease

ArticleYear
Current and developing therapeutic agents in the treatment of Chagas disease.
    Drug design, development and therapy, 2010, Sep-24, Volume: 4

    Topics: Acute Disease; Animals; Chagas Disease; Chronic Disease; Humans; Nifurtimox; Nitroimidazoles; Time Factors; Treatment Outcome; Trypanocidal Agents

2010
Chagas disease: Present status of pathogenic mechanisms and chemotherapy.
    Biological research, 2010, Volume: 43, Issue:3

    Topics: Acute Disease; Animals; Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Cyclooxygenase 1; Cyclooxygenase 2; Humans; Mice; Nifurtimox; Nitroimidazoles; Trypanocidal Agents; Trypanosoma cruzi

2010
Chagas disease: clinical overview and implications for nursing.
    Medsurg nursing : official journal of the Academy of Medical-Surgical Nurses, 2007, Volume: 16, Issue:4

    Topics: Acute Disease; Animals; Canada; Chagas Disease; Chronic Disease; Emigration and Immigration; Hispanic or Latino; Humans; Immunologic Tests; Incidence; Insect Control; Insect Vectors; Nifurtimox; Nitroimidazoles; Nurse's Role; Prevalence; Primary Prevention; Risk Factors; South America; Travel; Triatoma; Trypanocidal Agents; United States

2007

Other Studies

40 other study(ies) available for benzonidazole and Acute Disease

ArticleYear
2H-benzimidazole 1,3-dioxide derivatives: a new family of water-soluble anti-trypanosomatid agents.
    Journal of medicinal chemistry, 2006, Jun-01, Volume: 49, Issue:11

    Topics: Acute Disease; Animals; Benzimidazoles; Cell Line; Chagas Disease; Cyclic N-Oxides; Leishmania; Macrophages; Mice; Mice, Inbred BALB C; Models, Molecular; Oxidation-Reduction; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi

2006
Impact of dual infections on chemotherapeutic efficacy in BALB/c mice infected with major genotypes of Trypanosoma cruzi.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:9

    Topics: Acute Disease; Alleles; Animals; Chagas Disease; Drug Resistance; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Mice; Mice, Inbred BALB C; Microsatellite Repeats; Nitroimidazoles; Reverse Transcriptase Polymerase Chain Reaction; Trypanocidal Agents; Trypanosoma cruzi

2007
In vivo studies of 5-arylethenylbenzofuroxans in acute murine models of Chagas' disease.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:10

    Topics: Acute Disease; Animals; Antibodies, Protozoan; Benzoxazoles; Chagas Disease; Disease Models, Animal; Female; Mice; Parasitemia; Treatment Outcome; Trypanosoma cruzi

2008
New approach towards the synthesis of selenosemicarbazones, useful compounds for Chagas' disease.
    European journal of medicinal chemistry, 2016, Feb-15, Volume: 109

    Topics: Acute Disease; Animals; Chagas Disease; Chemistry Techniques, Synthetic; Drug Design; Male; Mice; Mice, Inbred BALB C; Organoselenium Compounds; Semicarbazones; Trypanocidal Agents; Trypanosoma cruzi

2016
New polyamine drugs as more effective antichagas agents than benznidazole in both the acute and chronic phases.
    European journal of medicinal chemistry, 2019, Feb-15, Volume: 164

    Topics: Acute Disease; Animals; Chagas Disease; Chronic Disease; Drug Design; Fluorenes; Humans; Microbodies; Nitroimidazoles; Polyamines; Solubility; Trypanocidal Agents; Trypanosoma cruzi

2019
Low-dose of benznidazole promotes therapeutic cure in experimental chronic Chagas' disease with absence of parasitism in blood, heart and colon.
    Experimental parasitology, 2020, Volume: 210

    Topics: Acute Disease; Animals; Blood; Chagas Disease; Chronic Disease; Colon; Cyclophosphamide; Female; Heart; Immunosuppression Therapy; Mice; Neglected Diseases; Nitroimidazoles; Real-Time Polymerase Chain Reaction; Trypanocidal Agents; Trypanosoma cruzi

2020
Efficacy of the Benznidazole+Posaconazole combination therapy in parasitemia reduction: An experimental murine model of acute Chagas.
    Revista da Sociedade Brasileira de Medicina Tropical, 2020, Volume: 53

    Topics: Acute Disease; Animals; Chagas Disease; Disease Models, Animal; Disease Progression; DNA, Protozoan; Drug Therapy, Combination; Nitroimidazoles; Parasite Load; Parasitemia; Rats; Rats, Wistar; Triazoles; Trypanocidal Agents

2020
Antiparasitic and anti-inflammatory activities of ß-lapachone-derived naphthoimidazoles in experimental acute Trypanosoma cruzi infection.
    Memorias do Instituto Oswaldo Cruz, 2020, Volume: 115

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Chagas Disease; Disease Models, Animal; Electrocardiography; Male; Mice; Naphthoquinones; Nitroimidazoles; Parasitemia; Time Factors; Trypanocidal Agents

2020
Benznidazole/Poloxamer 407 Solid Dispersion as a New Strategy to Improve the Treatment of Experimental Trypanosoma cruzi Infection.
    The Journal of parasitology, 2020, 06-01, Volume: 106, Issue:3

    Topics: Acute Disease; Animals; Antibodies, Protozoan; Aspartate Aminotransferases; Chagas Disease; Chronic Disease; Disease Models, Animal; Excipients; Female; Heart; Mice; Myocardium; Nitroimidazoles; Parasitemia; Poloxamer; Quadriceps Muscle; Random Allocation; Real-Time Polymerase Chain Reaction; Trypanocidal Agents; Trypanosoma cruzi

2020
    Parasitology, 2021, Volume: 148, Issue:5

    Topics: Acute Disease; Animals; Chagas Disease; Disease Models, Animal; Female; Mice; Nanoparticles; Nitroimidazoles; Trypanocidal Agents; Trypanosoma cruzi

2021
CD8low T cells expanded following acute Trypanosoma cruzi infection and benznidazole treatment are a relevant subset of IFN-γ producers.
    PLoS neglected tropical diseases, 2020, Volume: 14, Issue:12

    Topics: Acute Disease; Animals; CD8-Positive T-Lymphocytes; Chagas Disease; Female; Mice; Mice, Inbred C57BL; Nitroimidazoles; Spleen; Trypanocidal Agents; Trypanosoma cruzi

2020
Involvement of ectonucleotidases and purinergic receptor expression during acute Chagas disease in the cortex of mice treated with resveratrol and benznidazole.
    Purinergic signalling, 2021, Volume: 17, Issue:3

    Topics: Acute Disease; Animals; Antioxidants; Cerebral Cortex; Chagas Disease; Female; Gene Expression; Immunosuppressive Agents; Mice; Nitroimidazoles; Oxidative Stress; Receptors, Purinergic; Resveratrol

2021
Parasitaemia and parasitic load are limited targets of the aetiological treatment to control the progression of cardiac fibrosis and chronic cardiomyopathy in Trypanosoma cruzi-infected dogs.
    Acta tropica, 2019, Volume: 189

    Topics: Acute Disease; Animals; Chagas Cardiomyopathy; Chronic Disease; Collagen Type III; Disease Models, Animal; Disease Progression; DNA, Protozoan; Dogs; Drug Resistance; Fibrosis; Heart; Myocardium; Nitroimidazoles; Parasite Load; Parasitemia; Trypanocidal Agents; Trypanosoma cruzi

2019
The β-blocker carvedilol and the benznidazole modulate the cardiac immune response in the acute infection induced by Colombian strain of the Trypanosoma cruzi.
    Memorias do Instituto Oswaldo Cruz, 2018, Oct-18, Volume: 113, Issue:11

    Topics: Acute Disease; Adrenergic beta-Antagonists; Animals; Carvedilol; Catalase; Chagas Disease; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Heart; Male; Mice, Inbred C57BL; Myocardium; Nitroimidazoles; Oxidative Stress; Parasitemia; Protein Carbonylation; Reference Values; Reproducibility of Results; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Time Factors; Trypanocidal Agents; Trypanosoma cruzi

2018
Fatal evolution of acute Chagas disease in a child from Northern Brazil: factors that determine poor prognosis.
    Revista do Instituto de Medicina Tropical de Sao Paulo, 2019, May-06, Volume: 61

    Topics: Acute Disease; Chagas Disease; Fatal Outcome; Food Parasitology; Humans; Infant; Male; Nitroimidazoles; Prognosis; Trypanocidal Agents

2019
Benznidazole, itraconazole and their combination in the treatment of acute experimental chagas disease in dogs.
    Experimental parasitology, 2019, Volume: 204

    Topics: Acute Disease; Animals; Chagas Disease; DNA, Protozoan; Dogs; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Female; Heart; Humans; Itraconazole; Male; Myocardium; Nitroimidazoles; Parasitemia; Polymerase Chain Reaction; Random Allocation; Trypanocidal Agents

2019
In vivo activity of ursolic and oleanolic acids during the acute phase of Trypanosoma cruzi infection.
    Experimental parasitology, 2013, Volume: 134, Issue:4

    Topics: Acute Disease; Administration, Oral; Animals; Anti-Infective Agents; Chagas Disease; Disease Models, Animal; Infusions, Parenteral; Interferon-gamma; Interleukin-10; Male; Melastomataceae; Mice; Mice, Inbred BALB C; Nitroimidazoles; Oleanolic Acid; Parasitemia; Random Allocation; Triterpenes; Trypanocidal Agents; Ursolic Acid

2013
Clinical follow-up of responses to treatment with benznidazol in Amazon: a cohort study of acute Chagas disease.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Aged; Antibodies, Protozoan; Brazil; Chagas Cardiomyopathy; Chagas Disease; Child; Child, Preschool; Disease Progression; Follow-Up Studies; Humans; Immunoglobulin G; Middle Aged; Nitroimidazoles; Topography, Medical; Treatment Outcome; Trypanocidal Agents; Trypanosoma cruzi; Young Adult

2013
Acute Chagas outbreaks: molecular and biological features of Trypanosoma cruzi isolates, and clinical aspects of acute cases in Santander, Colombia.
    Parasites & vectors, 2015, Nov-26, Volume: 8

    Topics: Acute Disease; Animals; Base Sequence; Chagas Disease; Colombia; Disease Outbreaks; DNA, Protozoan; Exons; Female; Genetic Variation; Genotype; Humans; Male; Molecular Sequence Data; Nifurtimox; Nitroimidazoles; Sequence Analysis, DNA; Trypanocidal Agents; Trypanosoma cruzi

2015
Curcumin Enhances the Anti-Trypanosoma cruzi Activity of Benznidazole-Based Chemotherapy in Acute Experimental Chagas Disease.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:6

    Topics: Acute Disease; Animals; Chagas Disease; Curcumin; Cytokines; Female; Liver; Mice; Myocardium; Nitroimidazoles; Parasitemia; Transaminases; Trypanocidal Agents; Trypanosoma cruzi

2016
Efficacy of Lychnopholide Polymeric Nanocapsules after Oral and Intravenous Administration in Murine Experimental Chagas Disease.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:9

    Topics: Acute Disease; Administration, Intravenous; Administration, Oral; Animals; Chagas Disease; Chronic Disease; Delayed-Action Preparations; Disease Models, Animal; Drug Compounding; Humans; Lactones; Mice; Nanocapsules; Nitroimidazoles; Polyethylene Glycols; Sesquiterpenes; Survival Analysis; Treatment Outcome; Trypanocidal Agents; Trypanosoma cruzi

2016
Chronic Heart Disease after Treatment of Oral Acute Chagas Disease.
    Arquivos brasileiros de cardiologia, 2016, Volume: 107, Issue:2

    Topics: Acute Disease; Adolescent; Arrhythmias, Cardiac; Chagas Cardiomyopathy; Chagas Disease; Electrocardiography; Humans; Male; Nitroimidazoles; Recurrence; Trypanocidal Agents

2016
Trypanosoma cruzi: Genetic diversity influences the profile of immunoglobulins during experimental infection.
    Experimental parasitology, 2009, Volume: 121, Issue:1

    Topics: Acute Disease; Animals; Chagas Disease; Chronic Disease; Enzyme-Linked Immunosorbent Assay; Female; Genetic Variation; Genotype; Immunoglobulin G; Mice; Nitroimidazoles; Phylogeny; Random Allocation; Time Factors; Trypanocidal Agents; Trypanosoma cruzi

2009
Chagas' disease and its toll on the heart.
    European heart journal, 2009, Volume: 30, Issue:17

    Topics: Acute Disease; Arrhythmias, Cardiac; Brazil; Chagas Cardiomyopathy; Chronic Disease; Defibrillators, Implantable; Heart Failure; History, 20th Century; Humans; Nitroimidazoles; Nobel Prize; Trypanocidal Agents

2009
Effects of dehydroepiandrosterone-sulfate (DHEA-S) and benznidazole treatments during acute infection of two different Trypanosoma cruzi strains.
    Immunobiology, 2010, Volume: 215, Issue:12

    Topics: Acute Disease; Animals; Chagas Disease; Dehydroepiandrosterone Sulfate; Drug Therapy, Combination; Interferon-gamma; Interleukin-2; Macrophages, Peritoneal; Male; Nitrites; Nitroimidazoles; Parasitemia; Rats; Rats, Wistar; Species Specificity; Survival Rate; Time Factors; Treatment Outcome; Trypanocidal Agents; Trypanosoma cruzi

2010
Acute Chagas' disease in postrenal transplant and treatment with benzonidazole.
    Annals of diagnostic pathology, 2010, Volume: 14, Issue:3

    Topics: Acute Disease; Adult; Chagas Disease; Fatal Outcome; Humans; Immunocompromised Host; Immunosuppression Therapy; Immunosuppressive Agents; Kidney Transplantation; Male; Nitroimidazoles; Postoperative Complications; Renal Insufficiency; Trypanocidal Agents; Trypanosoma cruzi

2010
Clinical outcomes of thirteen patients with acute chagas disease acquired through oral transmission from two urban outbreaks in northeastern Brazil.
    PLoS neglected tropical diseases, 2010, Jun-15, Volume: 4, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Brazil; Chagas Disease; Child; Disease Outbreaks; Echocardiography, Doppler; Electrocardiography; Female; Humans; Male; Nitroimidazoles; Radiography, Thoracic; Treatment Outcome; Trypanocidal Agents; Trypanosoma cruzi

2010
Chagas disease 101.
    Nature, 2010, Jun-24, Volume: 465, Issue:7301

    Topics: Acute Disease; Animals; Carrier State; Chagas Disease; Chronic Disease; Clinical Trials as Topic; History, 16th Century; History, 19th Century; History, 20th Century; History, 21st Century; History, Ancient; Humans; Insect Vectors; Latin America; Neglected Diseases; Nitroimidazoles; Trypanocidal Agents; Trypanosoma cruzi

2010
Comparative efficacies of TAK-187, a long-lasting ergosterol biosynthesis inhibitor, and benznidazole in preventing cardiac damage in a murine model of Chagas' disease.
    Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:4

    Topics: Acute Disease; Animals; Chagas Cardiomyopathy; Chagas Disease; Disease Models, Animal; Ergosterol; Male; Mice; Nitroimidazoles; Triazoles; Trypanocidal Agents; Trypanosoma cruzi

2005
Trypanosoma cruzi: alteration in the lymphoid compartments following interruption of infection by early acute benznidazole therapy in mice.
    Experimental parasitology, 2006, Volume: 114, Issue:3

    Topics: Acute Disease; Animals; B-Lymphocytes; Chagas Disease; Immunity, Cellular; Lymph Nodes; Lymphoid Tissue; Male; Mice; Nitroimidazoles; Parasitemia; Spleen; T-Lymphocytes; Thymus Gland; Trypanocidal Agents; Trypanosoma cruzi

2006
Benznidazole therapy during acute phase of Chagas disease reduces parasite load but does not prevent chronic cardiac lesions.
    Parasitology research, 2008, Volume: 103, Issue:2

    Topics: Acute Disease; Animals; Chagas Disease; Chronic Disease; Drug Resistance; Heart; Humans; Mice; Myocardium; Nitroimidazoles; Parasitemia; Trypanocidal Agents; Trypanosoma cruzi

2008
Antibodies inhibiting Trypanosoma cruzi trans-sialidase activity in sera from human infections.
    The Journal of infectious diseases, 1994, Volume: 170, Issue:6

    Topics: Acute Disease; Animals; Antibodies, Protozoan; Antigens, Protozoan; Chagas Disease; Chronic Disease; Female; Glycoproteins; Humans; Immune Sera; Infant, Newborn; Neuraminidase; Neutralization Tests; Nitroimidazoles; Trypanocidal Agents; Trypanosoma cruzi

1994
Use of Trypanosoma cruzi purified glycoprotein (GP57/51) or trypomastigote-shed antigens to assess cure for human Chagas' disease.
    The American journal of tropical medicine and hygiene, 1993, Volume: 49, Issue:5

    Topics: Acute Disease; Adsorption; Adult; Animals; Antibodies, Protozoan; Antibody Specificity; Antigens, Protozoan; Chagas Disease; Child; Chronic Disease; Cross Reactions; Cysteine Endopeptidases; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Follow-Up Studies; Glycoproteins; Humans; Middle Aged; Nifurtimox; Nitroimidazoles; Treatment Outcome; Trypanocidal Agents; Trypanosoma cruzi

1993
Cardiac involvement is a constant finding in acute Chagas' disease: a clinical, parasitological and histopathological study.
    International journal of cardiology, 1997, Jun-27, Volume: 60, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Animals; Cardiomegaly; Chagas Cardiomyopathy; Child; Child, Preschool; Electrocardiography; Female; Humans; Infant; Male; Middle Aged; Myocardium; Nitroimidazoles; Pericardial Effusion; Trypanocidal Agents; Trypanosoma cruzi; Venezuela

1997
Interleukin-12 enhances in vivo parasiticidal effect of benznidazole during acute experimental infection with a naturally drug-resistant strain of Trypanosoma cruzi.
    Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:10

    Topics: Acute Disease; Animals; Chagas Disease; Drug Resistance; Interferon-gamma; Interleukin-12; Male; Mice; Mice, Inbred C3H; Nitroimidazoles; Polymerase Chain Reaction; Trypanocidal Agents

1998
Activities of the triazole derivative SCH 56592 (posaconazole) against drug-resistant strains of the protozoan parasite Trypanosoma (Schizotrypanum) cruzi in immunocompetent and immunosuppressed murine hosts.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:1

    Topics: Acute Disease; Animals; Chagas Disease; Chronic Disease; Drug Resistance; Female; Immunocompetence; Immunosuppression Therapy; Mice; Nitroimidazoles; Triazoles; Trypanocidal Agents; Trypanosoma cruzi

2000
Efficacy of the bisbenzylisoquinoline alkaloids in acute and chronic Trypanosoma cruzi murine model.
    International journal of antimicrobial agents, 2000, Volume: 13, Issue:3

    Topics: Acute Disease; Administration, Oral; Alkaloids; Animals; Benzylisoquinolines; Chagas Disease; Chronic Disease; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Immunoblotting; Isoquinolines; Male; Mice; Mice, Inbred BALB C; Nitroimidazoles; Parasitemia; Trypanocidal Agents

2000
TNF-alpha is expressed at sites of parasite and tissue destruction in the spleen of mice acutely infected with Trypanosoma cruzi.
    International journal of experimental pathology, 2001, Volume: 82, Issue:6

    Topics: Acute Disease; Animals; Chagas Disease; Disease Susceptibility; Immunoenzyme Techniques; Macrophages; Mice; Mice, Inbred C3H; Mice, Inbred DBA; Necrosis; Nitroimidazoles; Parasitemia; Spleen; Survival Rate; Trypanocidal Agents; Tumor Necrosis Factor-alpha

2001
Evaluation of the mutagenic potential of the antichagasic drug Rochagan in healthy and chagasic rodents.
    Mutation research, 1991, Volume: 259, Issue:2

    Topics: Acute Disease; Animals; Bone Marrow; Bone Marrow Cells; Chagas Disease; Chromosome Aberrations; Chromosomes; Chronic Disease; Dose-Response Relationship, Drug; Mice; Mice, Inbred BALB C; Micronucleus Tests; Nitroimidazoles; Rats; Rats, Inbred Strains; Time Factors; Trypanocidal Agents

1991
Shift of excretory-secretory immunogens of Trypanosoma cruzi during human Chagas' disease.
    Infection and immunity, 1991, Volume: 59, Issue:6

    Topics: Acute Disease; Animals; Antibodies, Protozoan; Antigens, Protozoan; Chagas Disease; Chronic Disease; Electrophoresis, Polyacrylamide Gel; Humans; Immunoblotting; Nitroimidazoles; Rabbits; Trypanocidal Agents; Trypanosoma cruzi

1991