benzoic acid has been researched along with Insulin Resistance in 1 studies
Benzoic Acid: A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid.
benzoic acid : A compound comprising a benzene ring core carrying a carboxylic acid substituent.
aromatic carboxylic acid : Any carboxylic acid in which the carboxy group is directly bonded to an aromatic ring.
Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In pursuing our aim to identify new agents able to improve cellular insulin sensitivity, we have synthesized new 4-[(5-arylidene-4-oxo-2-phenylimino/oxothiazolidin-3-yl)methyl]benzoic acids (5, 8) and evaluated their inhibitory activity towards human protein tyrosine phosphatases PTP1B, LMW-PTP and TCPTP, enzymes which are involved in the development of insulin resistance." | 3.80 | Synthesis, biological activity and structure-activity relationships of new benzoic acid-based protein tyrosine phosphatase inhibitors endowed with insulinomimetic effects in mouse C2C12 skeletal muscle cells. ( Amuso, S; Camici, G; Caselli, A; Maccari, R; Mortier, J; Ottanà , R; Paoli, P; Rotondo, A; Wolber, G, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ottanà , R | 1 |
| Maccari, R | 1 |
| Mortier, J | 1 |
| Caselli, A | 1 |
| Amuso, S | 1 |
| Camici, G | 1 |
| Rotondo, A | 1 |
| Wolber, G | 1 |
| Paoli, P | 1 |
1 other study available for benzoic acid and Insulin Resistance
| Article | Year |
|---|---|
Synthesis, biological activity and structure-activity relationships of new benzoic acid-based protein tyrosine phosphatase inhibitors endowed with insulinomimetic effects in mouse C2C12 skeletal muscle cells.
Topics: Animals; Benzoic Acid; Cell Line; Humans; Insulin; Insulin Resistance; Mice; Molecular Docking Simul | 2014 |