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benzoic acid and Hives

benzoic acid has been researched along with Hives in 20 studies

Benzoic Acid: A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid.
benzoic acid : A compound comprising a benzene ring core carrying a carboxylic acid substituent.
aromatic carboxylic acid : Any carboxylic acid in which the carboxy group is directly bonded to an aromatic ring.

Research Excerpts

ExcerptRelevanceReference
"To study the role played by prostaglandins (PGs) in contact urticaria, concentrations of 13,14-dihydro-15-keto-PGF2 alpha, 6-keto-PGF1 alpha, and thromboxane B2, the stable metabolites of PGF2 alpha, prostacycline and thromboxane A2 were measured by radio-immunoassay of the fluid taken from suction blisters in 11 patients."7.66Prostaglandins in contact urticaria induced by benzoic acid. ( Hannuksela, M; Lahti, A; Oikarinen, A; Viinikka, L; Ylikorkala, O, 1983)
" Twelve other patients with IgE-mediated allergy were treated by CFS on the lower arm for 1 h and were then pricked with histamine and allergen extracts (wheal volume was measured) and were tested using benzoic acid (nonimmunologic contact urticaria; closed test)."3.71Cutaneous field stimulation of sensory nerve fibers reduces itch without affecting contact dermatitis. ( Wallengren, J, 2002)
" 40 of the children were also tested for contact urticaria against food additives and fragrances, of whom 20 were positive (benzoic acid 14, cinnamaldehyde 12)."3.67Contact dermatitis in children. ( Forsyth, A; Rademaker, M, 1989)
"In some cases of chronic urticaria it is suspected that food additives such as tartrazine and sodium benzoate or salicylates may play a role in the pathogenesis of the condition."3.67Cell-mediated immune responses to artificial food additives in chronic urticaria. ( McPhillips, S; Sauder, PJ; Warrington, RJ, 1986)
"To investigate the mechanisms of non-immunologic contact urticaria (NICU), the effects of 1g + 1g of acetylsalicylic acid (ASA) on contact reactions to methyl nicotinate, diethyl fumarate, benzoic acid, cinnamic acid, cinnamic aldehyde and dimethyl sulfoxide were studied in 21 test subjects."3.67Acetylsalicylic acid inhibits non-immunologic contact urticaria. ( Hannuksela, M; Kokkonen, EL; Lahti, A; Väänänen, A, 1987)
"To study the role played by prostaglandins (PGs) in contact urticaria, concentrations of 13,14-dihydro-15-keto-PGF2 alpha, 6-keto-PGF1 alpha, and thromboxane B2, the stable metabolites of PGF2 alpha, prostacycline and thromboxane A2 were measured by radio-immunoassay of the fluid taken from suction blisters in 11 patients."3.66Prostaglandins in contact urticaria induced by benzoic acid. ( Hannuksela, M; Lahti, A; Oikarinen, A; Viinikka, L; Ylikorkala, O, 1983)
"In one, urticaria was induced by the colourings, in another extremely abnormal behaviour was induced by the preservatives and a third child was only free of asthma and abdominal pain on placebo."2.66A double-blind assessment of additive intolerance in children using a 12 day challenge period at home. ( Scott, A; Wilson, N, 1989)
"Benzoic Acid is an aromatic acid used in a wide variety of cosmetics as a pH adjuster and preservative."2.41Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate. ( Nair, B, 2001)
"Benzoic acid (BA) was used to induce nonimmunologic contact irritation in 10 younger (23-47 years old) and 5 older (72-90 years old) healthy volunteers."1.29Regional variation of nonimmunologic contact urticaria. Functional map of the human face. ( Maibach, HI; Shriner, DL, 1996)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199011 (55.00)18.7374
1990's6 (30.00)18.2507
2000's3 (15.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wallengren, J1
Lahti, A5
Hannuksela, M3
Oikarinen, A1
Viinikka, L1
Ylikorkala, O1
Nethercott, JR1
Lawrence, MJ1
Roy, AM1
Gibson, BL1
Muñoz, FJ1
Bellido, J1
Moyano, JC1
Alvarez, M1
Fonseca, JL1
Shriner, DL1
Maibach, HI2
Coverly, J1
Peters, L1
Whittle, E1
Basketter, DA2
Temesvári, E1
Podányi, B1
Horváth, A1
Nair, B1
Schaubschläger, WW1
Becker, WM1
Schade, U1
Zabel, P1
Schlaak, M1
Safford, RJ1
Allenby, CF1
Goodwin, BF1
Kligman, AM2
Rademaker, M1
Forsyth, A1
Wilson, N1
Scott, A1
Kujala, T1
Warrington, RJ1
Sauder, PJ1
McPhillips, S1
Väänänen, A1
Kokkonen, EL1
Kemp, AS1
Schembri, G1
Gollhausen, R1

Reviews

1 review available for benzoic acid and Hives

ArticleYear
Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate.
    International journal of toxicology, 2001, Volume: 20 Suppl 3

    Topics: Animals; Benzoic Acid; Benzyl Alcohol; Carcinogenicity Tests; Consumer Product Safety; Cosmetics; De

2001

Trials

2 trials available for benzoic acid and Hives

ArticleYear
Is benzoic acid really harmful in cases of atopy and urticaria?
    Lancet (London, England), 1981, Nov-07, Volume: 2, Issue:8254

    Topics: Benzoates; Benzoic Acid; Clinical Trials as Topic; Double-Blind Method; Humans; Hypersensitivity, Im

1981
A double-blind assessment of additive intolerance in children using a 12 day challenge period at home.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1989, Volume: 19, Issue:3

    Topics: Adolescent; Age Factors; Asthma; Azo Compounds; Benzoates; Benzoic Acid; Child; Child, Preschool; Do

1989

Other Studies

17 other studies available for benzoic acid and Hives

ArticleYear
Cutaneous field stimulation of sensory nerve fibers reduces itch without affecting contact dermatitis.
    Allergy, 2002, Volume: 57, Issue:12

    Topics: Administration, Cutaneous; Adult; Aged; Anti-Infective Agents, Local; Antifungal Agents; Benzalkoniu

2002
Prostaglandins in contact urticaria induced by benzoic acid.
    Acta dermato-venereologica, 1983, Volume: 63, Issue:5

    Topics: Adolescent; Adult; Benzoates; Benzoic Acid; Dermatitis, Contact; Dinoprost; Epoprostenol; Female; Hu

1983
Airborne contact urticaria due to sodium benzoate in a pharmaceutical manufacturing plant.
    Journal of occupational medicine. : official publication of the Industrial Medical Association, 1984, Volume: 26, Issue:10

    Topics: Adult; Air Pollutants, Occupational; Benzoates; Benzoic Acid; Dermatitis, Contact; Dermatitis, Occup

1984
Perioral contact urticaria from sodium benzoate in a toothpaste.
    Contact dermatitis, 1996, Volume: 35, Issue:1

    Topics: Benzoates; Benzoic Acid; Child, Preschool; Dermatitis, Contact; Dermatitis, Perioral; Food Preservat

1996
Regional variation of nonimmunologic contact urticaria. Functional map of the human face.
    Skin pharmacology : the official journal of the Skin Pharmacology Society, 1996, Volume: 9, Issue:5

    Topics: Adult; Aged; Aging; Benzoates; Benzoic Acid; Face; Female; Forearm; Humans; Hydrogen-Ion Concentrati

1996
Susceptibility to skin stinging, non-immunologic contact urticaria and acute skin irritation; is there a relationship?
    Contact dermatitis, 1998, Volume: 38, Issue:2

    Topics: Acrolein; Acute Disease; Administration, Topical; Adult; Anti-Inflammatory Agents; Antimutagenic Age

1998
Corticosteroid-delayed contact sensitivity and cross-reactions provoked by 20-mm patch test exposure.
    Contact dermatitis, 2000, Volume: 43, Issue:3

    Topics: Administration, Topical; Anti-Inflammatory Agents; Benzoic Acid; Cross Reactions; Dermatitis, Allerg

2000
Release of mediators from human gastric mucosa and blood in adverse reactions to benzoate.
    International archives of allergy and applied immunology, 1991, Volume: 96, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Aged; Asthma; Benzoates; Benzoic Acid; Dermatitis,

1991
Immediate contact reactions to chemicals in the fragrance mix and a study of the quenching action of eugenol.
    The British journal of dermatology, 1990, Volume: 123, Issue:5

    Topics: Acrolein; Adolescent; Adult; Aged; Animals; Benzoates; Benzoic Acid; Child; Child, Preschool; Dermat

1990
The spectrum of contact urticaria. Wheals, erythema, and pruritus.
    Dermatologic clinics, 1990, Volume: 8, Issue:1

    Topics: Acrolein; Benzoates; Benzoic Acid; Dermatitis, Contact; Erythema; Female; Humans; Pruritus; Sorbic A

1990
Contact dermatitis in children.
    Contact dermatitis, 1989, Volume: 20, Issue:2

    Topics: Acrolein; Benzoates; Benzoic Acid; Child; Child, Preschool; Dermatitis, Contact; Female; Humans; Mal

1989
Duration of inhibition of non-immunologic immediate contact reactions by acetylsalicylic acid.
    Contact dermatitis, 1989, Volume: 21, Issue:1

    Topics: Adult; Aspirin; Benzoates; Benzoic Acid; Dermatitis, Contact; Female; Humans; Male; Nicotinic Acids;

1989
Cell-mediated immune responses to artificial food additives in chronic urticaria.
    Clinical allergy, 1986, Volume: 16, Issue:6

    Topics: Adolescent; Adult; Aspirin; Benzoates; Benzoic Acid; Cell Migration Inhibition; Chronic Disease; Fem

1986
Acetylsalicylic acid inhibits non-immunologic contact urticaria.
    Contact dermatitis, 1987, Volume: 16, Issue:3

    Topics: Acrolein; Adult; Aspirin; Benzoates; Benzoic Acid; Cinnamates; Dimethyl Sulfoxide; Female; Fumarates

1987
An elimination diet for chronic urticaria of childhood.
    The Medical journal of Australia, 1985, Sep-16, Volume: 143, Issue:6

    Topics: Adolescent; Aspirin; Benzoates; Benzoic Acid; Child; Child, Preschool; Chronic Disease; Drug Hyperse

1985
Human assay for identifying substances which induce non-allergic contact urticaria: the NICU-test.
    Contact dermatitis, 1985, Volume: 13, Issue:2

    Topics: Acrolein; Adult; Benzoates; Benzoic Acid; Dimethyl Sulfoxide; Drug Evaluation, Preclinical; Female;

1985
Long refractory period after one application of nonimmunologic contact urticaria agents to the guinea pig ear.
    Journal of the American Academy of Dermatology, 1985, Volume: 13, Issue:4

    Topics: Acrolein; Animals; Benzoates; Benzoic Acid; Cinnamates; Dimethyl Sulfoxide; Ear; Female; Fumarates;

1985