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benzoic acid and Hepatic Encephalopathy

benzoic acid has been researched along with Hepatic Encephalopathy in 8 studies

Benzoic Acid: A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid.
benzoic acid : A compound comprising a benzene ring core carrying a carboxylic acid substituent.
aromatic carboxylic acid : Any carboxylic acid in which the carboxy group is directly bonded to an aromatic ring.

Hepatic Encephalopathy: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)

Research Excerpts

ExcerptRelevanceReference
"We successfully anesthetized a 53-year-old female with hypercitrullinemia and severe liver cirrhosis."7.69[Anesthetic management for a patient with citrullinemia and liver cirrhosis]. ( Igarashi, M; Iwasaki, H; Kawana, S; Namiki, A, 1995)
" Seventy-four consecutive patients with cirrhosis or surgical portasystemic anastomosis and hepatic encephalopathy of less than 7 days duration were randomized to receive lactulose (dose adjusted for 2 or 3 semiformed stools/day) or sodium benzoate (5 gm twice daily)."5.07Sodium benzoate in the treatment of acute hepatic encephalopathy: a double-blind randomized trial. ( Bhist, MS; Dasarathy, S; Gupta, S; Jain, S; Sushma, S; Tandon, RK, 1992)
"We successfully anesthetized a 53-year-old female with hypercitrullinemia and severe liver cirrhosis."3.69[Anesthetic management for a patient with citrullinemia and liver cirrhosis]. ( Igarashi, M; Iwasaki, H; Kawana, S; Namiki, A, 1995)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's5 (62.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Campollo, O1
Cortéz, R1
Gutiérrez, M1
Odor, A1
Muñoz, RM1
Igarashi, M1
Kawana, S1
Iwasaki, H1
Namiki, A1
Bañares, R1
Carneros, JA1
Rincón, D1
Sushma, S1
Dasarathy, S1
Tandon, RK1
Jain, S1
Gupta, S1
Bhist, MS1
Wada, S1
Matsuo, K1
Nozawa, K1
Yazaki, K1
Suzuki, Y1
Nishizawa, K1
Sakai, H1
Huruta, S1
Ujihira, N1
Ohya, M1
Mabuchi, C1
Indo, T1
Hashizume, Y1
Maier, KP1
Mendenhall, CL1
Rouster, S1
Marshall, L1
Weesner, R1

Reviews

3 reviews available for benzoic acid and Hepatic Encephalopathy

ArticleYear
[New treatments of hepatic encephalopathy].
    Gastroenterologia y hepatologia, 1998, Volume: 21, Issue:4

    Topics: Amino Acids, Branched-Chain; Animals; Benzoates; Benzoic Acid; Clinical Trials as Topic; Electrocard

1998
[An autopsied case of type II citrullinemia--transient effectiveness with either citrate or benzoate to the consciousness disturbance].
    Rinsho shinkeigaku = Clinical neurology, 1989, Volume: 29, Issue:4

    Topics: Adult; Benzoates; Benzoic Acid; Citrates; Citric Acid; Citrulline; Cognition Disorders; Consciousnes

1989
[Therapy of hepatic encephalopathy].
    Deutsche medizinische Wochenschrift (1946), 1988, Dec-02, Volume: 113, Issue:48

    Topics: Amino Acids, Branched-Chain; Benzoates; Benzoic Acid; Clinical Trials as Topic; Hepatic Encephalopat

1988

Trials

3 trials available for benzoic acid and Hepatic Encephalopathy

ArticleYear
Sodium benzoate in the treatment of acute hepatic encephalopathy: a double-blind randomized trial.
    Hepatology (Baltimore, Md.), 1992, Volume: 16, Issue:1

    Topics: Acute Disease; Adult; Benzoates; Benzoic Acid; Brain; Double-Blind Method; Electroencephalography; E

1992
[Therapy of hepatic encephalopathy].
    Deutsche medizinische Wochenschrift (1946), 1988, Dec-02, Volume: 113, Issue:48

    Topics: Amino Acids, Branched-Chain; Benzoates; Benzoic Acid; Clinical Trials as Topic; Hepatic Encephalopat

1988
A new therapy for portal systemic encephalopathy.
    The American journal of gastroenterology, 1986, Volume: 81, Issue:7

    Topics: Aged; Ammonia; Benzoates; Benzoic Acid; Double-Blind Method; Drug Evaluation; Hepatic Encephalopathy

1986

Other Studies

3 other studies available for benzoic acid and Hepatic Encephalopathy

ArticleYear
Sodium benzoate and lactulose for the treatment of hepatic encephalopathy.
    Journal of hepatology, 1994, Volume: 21, Issue:6

    Topics: Animals; Benzoates; Benzoic Acid; Drug Synergism; Hepatic Encephalopathy; Lactulose; Rats; Rats, Wis

1994
[Anesthetic management for a patient with citrullinemia and liver cirrhosis].
    Masui. The Japanese journal of anesthesiology, 1995, Volume: 44, Issue:1

    Topics: Ammonia; Anesthesia, Spinal; Benzoates; Benzoic Acid; Citrulline; Female; Femoral Neck Fractures; He

1995
[A case of citrullinemia with fair response to oral administration of sodium benzoate for consciousness disturbance].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1991, Volume: 88, Issue:9

    Topics: Adult; Amino Acid Metabolism, Inborn Errors; Argininosuccinate Synthase; Benzoates; Benzoic Acid; Ci

1991