benzoic acid has been researched along with Disease Models, Animal in 14 studies
Benzoic Acid: A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid.
benzoic acid : A compound comprising a benzene ring core carrying a carboxylic acid substituent.
aromatic carboxylic acid : Any carboxylic acid in which the carboxy group is directly bonded to an aromatic ring.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The hydroxyl radical scavengers dimethylthiourea (DMTU), sodium benzoate, and dimethylsulfoxide (DMSO) were administered to rats before doxorubicin hydrochloride (ADR) (5 mg/kg, IV) to probe the role of free radicals in mediating proteinuria in doxorubicin hydrochloride nephrosis (AN)." | 7.68 | Amelioration of glomerular injury in doxorubicin hydrochloride nephrosis by dimethylthiourea. ( Houser, MT; Milner, LS; Wei, SH, 1991) |
| " The results showed that a dosage of 0." | 5.91 | A blend of formic acid, benzoic acid, and tributyrin alleviates ETEC K88-induced intestinal barrier dysfunction by regulating intestinal inflammation and gut microbiota in a murine model. ( Chen, J; Hu, Y; Xia, Y; You, J; Zhao, X; Zou, T, 2023) |
| "The hydroxyl radical scavengers dimethylthiourea (DMTU), sodium benzoate, and dimethylsulfoxide (DMSO) were administered to rats before doxorubicin hydrochloride (ADR) (5 mg/kg, IV) to probe the role of free radicals in mediating proteinuria in doxorubicin hydrochloride nephrosis (AN)." | 3.68 | Amelioration of glomerular injury in doxorubicin hydrochloride nephrosis by dimethylthiourea. ( Houser, MT; Milner, LS; Wei, SH, 1991) |
| " The results showed that a dosage of 0." | 1.91 | A blend of formic acid, benzoic acid, and tributyrin alleviates ETEC K88-induced intestinal barrier dysfunction by regulating intestinal inflammation and gut microbiota in a murine model. ( Chen, J; Hu, Y; Xia, Y; You, J; Zhao, X; Zou, T, 2023) |
| "Nonalcoholic fatty liver disease (NAFLD) is now the most common chronic liver disease, while there is still no medicine available." | 1.56 | Design, synthesis and structure-activity relationship studies of novel partial FXR agonists for the treatment of fatty liver. ( Chen, Y; Geng, R; Qiu, Q; Wang, W; Xu, X; Zhao, S; Zhao, X; Zhu, J, 2020) |
| " In the pyridine series, compound 7a was found to be a highly potent and selective EP4 antagonist, with suitable rat and dog pharmacokinetic profiles." | 1.43 | Discovery of potent aryl-substituted 3-[(3-methylpyridine-2-carbonyl) amino]-2,4-dimethyl-benzoic acid EP4 antagonists with improved pharmacokinetic profile. ( Blanco, MJ; Chambers, M; Chandrasekhar, S; Fisher, MJ; Harvey, A; Lin, C; Mudra, D; Oskins, J; Vetman, T; Wang, XS; Warshawsky, AM; Yu, XP, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 4 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, J | 3 |
| Xia, Y | 2 |
| Hu, Y | 2 |
| Zhao, X | 3 |
| You, J | 2 |
| Zou, T | 2 |
| Chen, C | 1 |
| Tian, J | 1 |
| Gao, X | 1 |
| Qin, X | 1 |
| Du, G | 1 |
| Zhou, Y | 1 |
| Qiu, Q | 1 |
| Wang, W | 1 |
| Chen, Y | 1 |
| Zhao, S | 1 |
| Zhu, J | 1 |
| Xu, X | 1 |
| Geng, R | 1 |
| Zheng, LT | 1 |
| Zhang, L | 1 |
| Zhang, Y | 1 |
| Xu, L | 1 |
| Hou, T | 1 |
| Zhen, X | 1 |
| Dai, Q | 1 |
| Liu, H | 1 |
| Guo, J | 1 |
| Yan, B | 1 |
| Wang, F | 1 |
| Gao, QH | 1 |
| Zhang, XJ | 1 |
| Yu, GJ | 1 |
| Zeng, Y | 1 |
| Qiu, JF | 1 |
| Geng, Q | 1 |
| Han, Q | 1 |
| Li, PP | 1 |
| Wang, WP | 1 |
| Liu, ZH | 1 |
| Xu, SF | 1 |
| Lu, WW | 1 |
| Wang, L | 1 |
| Wang, XL | 1 |
| Rosen, J | 1 |
| Landriscina, A | 1 |
| Ray, A | 1 |
| Tesfa, L | 1 |
| Nosanchuk, JD | 1 |
| Friedman, AJ | 1 |
| Blanco, MJ | 1 |
| Vetman, T | 1 |
| Chandrasekhar, S | 1 |
| Fisher, MJ | 1 |
| Harvey, A | 1 |
| Chambers, M | 1 |
| Lin, C | 1 |
| Mudra, D | 1 |
| Oskins, J | 1 |
| Wang, XS | 1 |
| Yu, XP | 1 |
| Warshawsky, AM | 1 |
| Jiang, H | 1 |
| Quilley, J | 1 |
| Doumad, AB | 1 |
| Zhu, AG | 1 |
| Falck, JR | 1 |
| Hammock, BD | 1 |
| Stier, CT | 1 |
| Carroll, MA | 1 |
| Ratnakumari, L | 1 |
| Qureshi, IA | 2 |
| Butterworth, RF | 1 |
| Michalak, A | 1 |
| Patejunas, G | 1 |
| Lee, B | 1 |
| Dennis, JA | 1 |
| Healy, PJ | 1 |
| Reeds, PJ | 1 |
| Yu, H | 1 |
| Frazer, M | 1 |
| Mull, B | 1 |
| Warman, AW | 1 |
| Beaudet, AL | 1 |
| O'Brien, WE | 1 |
| Milner, LS | 1 |
| Wei, SH | 1 |
| Houser, MT | 1 |
| Moon, KC | 1 |
| Wester, RC | 1 |
| Maibach, HI | 1 |
14 other studies available for benzoic acid and Disease Models, Animal
| Article | Year |
|---|---|
A blend of formic acid, benzoic acid, and tributyrin alleviates ETEC K88-induced intestinal barrier dysfunction by regulating intestinal inflammation and gut microbiota in a murine model.
Topics: Animals; Benzoic Acid; Disease Models, Animal; Enterotoxigenic Escherichia coli; Escherichia coli In | 2023 |
A blend of formic acid, benzoic acid, and tributyrin alleviates ETEC K88-induced intestinal barrier dysfunction by regulating intestinal inflammation and gut microbiota in a murine model.
Topics: Animals; Benzoic Acid; Disease Models, Animal; Enterotoxigenic Escherichia coli; Escherichia coli In | 2023 |
A blend of formic acid, benzoic acid, and tributyrin alleviates ETEC K88-induced intestinal barrier dysfunction by regulating intestinal inflammation and gut microbiota in a murine model.
Topics: Animals; Benzoic Acid; Disease Models, Animal; Enterotoxigenic Escherichia coli; Escherichia coli In | 2023 |
A blend of formic acid, benzoic acid, and tributyrin alleviates ETEC K88-induced intestinal barrier dysfunction by regulating intestinal inflammation and gut microbiota in a murine model.
Topics: Animals; Benzoic Acid; Disease Models, Animal; Enterotoxigenic Escherichia coli; Escherichia coli In | 2023 |
An integrated strategy to study the combination mechanisms of Bupleurum chinense DC and Paeonia lactiflora Pall for treating depression based on correlation analysis between serum chemical components profiles and endogenous metabolites profiles.
Topics: Aconitic Acid; Animals; Benzoic Acid; Carboxy-Lyases; Depression; Disease Models, Animal; Drugs, Chi | 2023 |
Design, synthesis and structure-activity relationship studies of novel partial FXR agonists for the treatment of fatty liver.
Topics: Animals; Benzoic Acid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; HEK293 | 2020 |
Inhibition of neuroinflammation by MIF inhibitor 3-({[4-(4-methoxyphenyl)-6-methyl-2-pyrimidinyl]thio}1methyl)benzoic acid (Z-312).
Topics: Animals; Anti-Inflammatory Agents; Benzoic Acid; Cells, Cultured; Disease Models, Animal; Humans; Li | 2021 |
[Establishment of a rat model of premature ejaculation with 8-OH-DPAT].
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzoic Acid; Disease Models, Animal; Ejaculation; | 2018 |
Potassium 2-(1-hydroxypentyl)-benzoate promotes long-term potentiation in Aβ1-42-injected rats and APP/PS1 transgenic mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzoates; Benzoi | 2014 |
Bensal HP Treatment for Burn and Excision Wounds: An In-Vivo Assessment of Wound Healing Efficacy and Immunological Impact.
Topics: Administration, Cutaneous; Animals; Benzoic Acid; Burns; Collagen; Cytokines; Dermatologic Agents; D | 2015 |
Discovery of potent aryl-substituted 3-[(3-methylpyridine-2-carbonyl) amino]-2,4-dimethyl-benzoic acid EP4 antagonists with improved pharmacokinetic profile.
Topics: Animals; Benzoic Acid; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Half-Life; Humans | 2016 |
Increases in plasma trans-EETs and blood pressure reduction in spontaneously hypertensive rats.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acids; Benzoic Acid; Blood Pressure; Disease Model | 2011 |
Effect of sodium benzoate on cerebral and hepatic energy metabolites in spf mice with congenital hyperammonemia.
Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Ammonia; Animals; Benzoates; Benzoic Acid; Brain; Coenzym | 1993 |
Free and esterified coenzyme A in the liver and muscles of chronically hyperammonemic mice treated with sodium benzoate.
Topics: Acetyl Coenzyme A; Ammonia; Animals; Benzoates; Benzoic Acid; Chronic Disease; Coenzyme A; Disease M | 1995 |
Evaluation of gene therapy for citrullinaemia using murine and bovine models.
Topics: Adenoviruses, Human; Amino Acid Metabolism, Inborn Errors; Ammonia; Animals; Arginine; Argininosucci | 1998 |
Amelioration of glomerular injury in doxorubicin hydrochloride nephrosis by dimethylthiourea.
Topics: Acetylglucosaminidase; Albuminuria; Animals; Benzoates; Benzoic Acid; Creatine; Dimethyl Sulfoxide; | 1991 |
Diseased skin models in the hairless guinea pig: in vivo percutaneous absorption.
Topics: Administration, Topical; Animals; Benzoates; Benzoic Acid; Disease Models, Animal; Female; Guinea Pi | 1990 |