benzoic acid has been researched along with Alzheimer Disease in 5 studies
Benzoic Acid: A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid.
benzoic acid : A compound comprising a benzene ring core carrying a carboxylic acid substituent.
aromatic carboxylic acid : Any carboxylic acid in which the carboxy group is directly bonded to an aromatic ring.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| " As a consequence, we conclude that clinical efficacy associated with chronic administration of sodium benzoate in schizophrenic and Alzheimer's patients is likely not mediated through inhibition of DAAO." | 1.48 | Lack of Effect of Sodium Benzoate at Reported Clinical Therapeutic Concentration on d-Alanine Metabolism in Dogs. ( DeVivo, M; Popiolek, M; Steyn, SJ; Tierney, B, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Popiolek, M | 1 |
| Tierney, B | 1 |
| Steyn, SJ | 1 |
| DeVivo, M | 1 |
| Kashima, Y | 1 |
| Miyazawa, M | 1 |
| Li, PP | 1 |
| Wang, WP | 1 |
| Liu, ZH | 1 |
| Xu, SF | 1 |
| Lu, WW | 1 |
| Wang, L | 1 |
| Wang, XL | 1 |
| LeVine, H | 1 |
| Lampe, L | 1 |
| Abdelmoti, L | 1 |
| Augelli-Szafran, CE | 1 |
| van Rensburg, SJ | 1 |
| van Zyl, JM | 1 |
| Potocnik, FC | 1 |
| Daniels, WM | 1 |
| Uys, J | 1 |
| Marais, L | 1 |
| Hon, D | 1 |
| van der Walt, BJ | 1 |
| Erasmus, RT | 1 |
5 other studies available for benzoic acid and Alzheimer Disease
| Article | Year |
|---|---|
Lack of Effect of Sodium Benzoate at Reported Clinical Therapeutic Concentration on d-Alanine Metabolism in Dogs.
Topics: Alanine; Alzheimer Disease; Animals; Benzoic Acid; Cognitive Dysfunction; D-Amino-Acid Oxidase; Dogs | 2018 |
Structure-activity relationships for bergenin analogues as β-secretase (BACE1) inhibitors.
Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Antioxidants; Aspartic Acid Endopeptidases; | 2013 |
Potassium 2-(1-hydroxypentyl)-benzoate promotes long-term potentiation in Aβ1-42-injected rats and APP/PS1 transgenic mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzoates; Benzoi | 2014 |
Dihydroxybenzoic acid isomers differentially dissociate soluble biotinyl-Aβ(1-42) oligomers.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Benzoic Acid; Biotinylation; Catechols; Dopamine; Glutaral | 2012 |
The effect of stress on the antioxidative potential of serum: implications for Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Antioxidants; Benzoic Acid; Hydroxylation; Male; Rats; Rats, Sprague-Daw | 2006 |