benzofurans and Cocarcinogenesis

benzofurans has been researched along with Cocarcinogenesis* in 2 studies

Other Studies

2 other study(ies) available for benzofurans and Cocarcinogenesis

Article	Year
[Influences of polychlorinated dibenzofuran on carcinogenesis]. Fukuoka igaku zasshi = Hukuoka acta medica, 1987, Volume: 78, Issue:5 Topics: Animals; Benzofurans; Cocarcinogenesis; Methylcholanthrene; Mice; Polymers; Skin; Skin Neoplasms	1987
Promoting effects of polychlorinated biphenyls (Aroclor 1254) and polychlorinated dibenzofuran-free Aroclor 1254 on diethylnitrosamine-induced tumorigenesis in the rat. Journal of the National Cancer Institute, 1981, Volume: 66, Issue:3 The hepatic tumor-promoting activity of a commercial polychlorinated biphenyl mixture, Aroclor 1254 (AR 1254), with and without its intrinsic polychlorinated dibenzofuran (PCDF) impurities, was investigated. Male Sprague-Dawley non-inbred albino rats were treated with 66 microgram diethylnitrosamine (DENA)/ml drinking water for 5 weeks and subsequently given a control diet or a diet supplemented (100 ppm for 18 wk) with either AR 1254 or AR 1254 from which the PCDF moieties were removed (AR 1254-PCDF). Of those animals receiving DENA alone, 16% exhibited hepatocellular carcinomas. Of those rats treated with DENA followed by administration of AR 1254 or AR 1254-PCDF, 64 or 84%, respectively, developed hepatocellular carcinomas. Thus promotion with either AR 1254 or AR 1254-PCDF significantly (P less than 0.05) increased the incidence of DENA-initiated hepatocellular carcinomas. Administration of AR 1254 or AR 1254-PCDF alone did not induce hepatic tumors. Therefore, PCDF impurities were not necessary for the promoting activity of AR 1254. Topics: Animals; Aroclors; Benzofurans; Body Weight; Carcinogens; Chlorodiphenyl (54% Chlorine); Cocarcinogenesis; Diet; Diethylnitrosamine; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Polychlorinated Biphenyls; Rats	1981

Article

Year

[Influences of polychlorinated dibenzofuran on carcinogenesis].

Fukuoka igaku zasshi = Hukuoka acta medica, 1987, Volume: 78, Issue:5

Topics: Animals; Benzofurans; Cocarcinogenesis; Methylcholanthrene; Mice; Polymers; Skin; Skin Neoplasms

1987

Promoting effects of polychlorinated biphenyls (Aroclor 1254) and polychlorinated dibenzofuran-free Aroclor 1254 on diethylnitrosamine-induced tumorigenesis in the rat.

Journal of the National Cancer Institute, 1981, Volume: 66, Issue:3

The hepatic tumor-promoting activity of a commercial polychlorinated biphenyl mixture, Aroclor 1254 (AR 1254), with and without its intrinsic polychlorinated dibenzofuran (PCDF) impurities, was investigated. Male Sprague-Dawley non-inbred albino rats were treated with 66 microgram diethylnitrosamine (DENA)/ml drinking water for 5 weeks and subsequently given a control diet or a diet supplemented (100 ppm for 18 wk) with either AR 1254 or AR 1254 from which the PCDF moieties were removed (AR 1254-PCDF). Of those animals receiving DENA alone, 16% exhibited hepatocellular carcinomas. Of those rats treated with DENA followed by administration of AR 1254 or AR 1254-PCDF, 64 or 84%, respectively, developed hepatocellular carcinomas. Thus promotion with either AR 1254 or AR 1254-PCDF significantly (P less than 0.05) increased the incidence of DENA-initiated hepatocellular carcinomas. Administration of AR 1254 or AR 1254-PCDF alone did not induce hepatic tumors. Therefore, PCDF impurities were not necessary for the promoting activity of AR 1254.

Topics: Animals; Aroclors; Benzofurans; Body Weight; Carcinogens; Chlorodiphenyl (54% Chlorine); Cocarcinogenesis; Diet; Diethylnitrosamine; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Polychlorinated Biphenyls; Rats

1981