benzofurans and Blepharoptosis

benzofurans has been researched along with Blepharoptosis* in 1 studies

Other Studies

1 other study(ies) available for benzofurans and Blepharoptosis

Article	Year
Synthesis of spiro[isobenzofuran-1(3H),4'-piperidines] as potential central nervous system agents. 2. Compounds containing a heteroatom attached to nitrogen. Journal of medicinal chemistry, 1977, Volume: 20, Issue:4 The synthesis and antitetrabenazine activity of a series of N-heteroatom derivatives of 3-phenylspiro[isobenzofuran-1,4'-piperidines] are reported. Optimal antitetrabenazine activity is associated with compounds containing a sterically unhindered, basic nitrogen. Hydroxylamines 6, 11, 12, and 13 possess the most significant activity with ED50's of 1.4, 3.5, 4.7, and 4.0, respectively. Topics: Animals; Antidepressive Agents; Benzofurans; Blepharoptosis; Methods; Mice; Piperidines; Structure-Activity Relationship; Tetrabenazine	1977

Article

Year

Synthesis of spiro[isobenzofuran-1(3H),4'-piperidines] as potential central nervous system agents. 2. Compounds containing a heteroatom attached to nitrogen.

Journal of medicinal chemistry, 1977, Volume: 20, Issue:4

The synthesis and antitetrabenazine activity of a series of N-heteroatom derivatives of 3-phenylspiro[isobenzofuran-1,4'-piperidines] are reported. Optimal antitetrabenazine activity is associated with compounds containing a sterically unhindered, basic nitrogen. Hydroxylamines 6, 11, 12, and 13 possess the most significant activity with ED50's of 1.4, 3.5, 4.7, and 4.0, respectively.

Topics: Animals; Antidepressive Agents; Benzofurans; Blepharoptosis; Methods; Mice; Piperidines; Structure-Activity Relationship; Tetrabenazine

1977