benzocaine has been researched along with Pregnancy in 9 studies
Benzocaine: A surface anesthetic that acts by preventing transmission of impulses along NERVE FIBERS and at NERVE ENDINGS.
dextran sulfate sodium : An organic sodium salt of dextran sulfate. It induces colitis in mice.
benzocaine : A benzoate ester having 4-aminobenzoic acid as the acid component and ethanol as the alcohol component. A surface anaesthetic, it is used to suppress the gag reflex, and as a lubricant and topical anaesthetic on the larynx, mouth, nasal cavity, respiratory tract, oesophagus, rectum, urinary tract, and vagina.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Topical benzocaine sprays used to relieve perineal pain in postpartum patients can, rarely, lead to methemoglobinemia." | 3.80 | Acute dyspnea in a postpartum patient. ( Fittro, K; Nichols, W, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fittro, K | 1 |
| Nichols, W | 1 |
| Gimovsky, A | 1 |
| Khodak-Gelman, S | 1 |
| Larsen, J | 1 |
| Guay, J | 1 |
| MEYER, H | 1 |
| Moes, D | 1 |
| Cora-Bramble, D | 1 |
| Hollander, A | 1 |
| Goldstein, PJ | 1 |
| Lipman, M | 1 |
| Luebehusen, J | 1 |
| Torres, HB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Methemoglobin Levels in Generally Anesthetized Pediatric Dental Patients Receiving Prilocaine Versus Lidocaine[NCT01402869] | 91 participants (Actual) | Interventional | 2011-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Change in percentage of methemoglobin in blood from baseline level to peak level (NCT01402869)
Timeframe: From administration of local anesthetic or start of restorative procedures to time at which maximum methemoglobin blood level was documented during dental treatment for an average of 2 hours
| Intervention | percentage of methemoglobin in blood (Mean) |
|---|---|
| Prilocaine | 2.73 |
| Lidocaine | 0.78 |
| No Local Anesthetic | 0.76 |
The maximum percentage of methemoglobin in blood (NCT01402869)
Timeframe: Measured at 10 second intervals during dental treatment for an average of 2 hours
| Intervention | percentage of methemoglobin in blood (Mean) |
|---|---|
| Prilocaine | 3.55 |
| Lidocaine | 1.63 |
| No Local Anesthetic | 1.60 |
The length of time between the administration of local anesthetic (Prilocaine and Lidocaine Groups) or start of restorative dental procedures (No local anesthetic Group) and the time at which the maximum methemoglobin blood level is observed. (NCT01402869)
Timeframe: Measured at 10 second intervals during dental treatment for an average of 2 hours
| Intervention | minutes (Mean) |
|---|---|
| Prilocaine | 62.73 |
| Lidocaine | 57.50 |
| No Local Anesthetic | 29.50 |
1 review available for benzocaine and Pregnancy
| Article | Year |
|---|---|
Methemoglobinemia related to local anesthetics: a summary of 242 episodes.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anemia; Anesthetics, Local; Benzocaine; Chi | 2009 |
1 trial available for benzocaine and Pregnancy
| Article | Year |
|---|---|
A controlled clinical trial of two local agents in postepisiotomy pain and discomfort.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anesthetics, Local; Benzocaine; Edema; Episiotomy; Femal | 1977 |
7 other studies available for benzocaine and Pregnancy
| Article | Year |
|---|---|
Acute dyspnea in a postpartum patient.
Topics: Adult; Anesthetics, Local; Benzocaine; Dyspnea; Enzyme Inhibitors; Female; Humans; Methemoglobinemia | 2014 |
Making chorionic villus sampling painless for both the patient and the physician.
Topics: Administration, Topical; Anesthetics, Local; Benzocaine; Chorionic Villi Sampling; Female; Humans; I | 2014 |
POSTPARTUM CARE OF THE PERINEUM: THE USE OF A TOPICAL ANESTHETIC SPRAY.
Topics: Aerosols; Anesthetics; Anesthetics, Local; Benzocaine; Female; Humans; Parabens; Perineum; Postnatal | 1964 |
Giving birth: a midwife's faith in birth is reborn.
Topics: Adult; Benzocaine; Female; Home Childbirth; Humans; Infant, Newborn; Midwifery; Mothers; Narration; | 2005 |
Silhouette of pain.
Topics: Adult; Benzocaine; Chickenpox; Child; Child Welfare; Chronic Disease; Family Health; Female; Hepatit | 2006 |
[Recent advances in American dermatology].
Topics: Adolescent; Adult; Benzocaine; Deafness; Dermatomycoses; Erythema; Female; Histiocytosis, Langerhans | 1982 |
[Use of an aerosol in obstetrics].
Topics: Adolescent; Adult; Aerosols; Benzocaine; Episiotomy; Female; Humans; Infant, Newborn; Postoperative | 1971 |