benzocaine has been researched along with Pharyngitis in 9 studies
Benzocaine: A surface anesthetic that acts by preventing transmission of impulses along NERVE FIBERS and at NERVE ENDINGS.
dextran sulfate sodium : An organic sodium salt of dextran sulfate. It induces colitis in mice.
benzocaine : A benzoate ester having 4-aminobenzoic acid as the acid component and ethanol as the alcohol component. A surface anaesthetic, it is used to suppress the gag reflex, and as a lubricant and topical anaesthetic on the larynx, mouth, nasal cavity, respiratory tract, oesophagus, rectum, urinary tract, and vagina.
Pharyngitis: Inflammation of the throat (PHARYNX).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Benzocaine lozenges are popular in symptomatic treatment of acute sore throat." | 9.16 | Efficacy of a benzocaine lozenge in the treatment of uncomplicated sore throat. ( Beime, B; Chrubasik, S; Magora, F, 2012) |
| "In a reference-controlled double-blind trial in patients with acute pharyngitis the effects of a newly developed lozenge containing 8 mg of benzocaine (p-aminobenzoic acid ethyl ester, CAS 94-09-7) were compared with those of an identically dosed commercial pastille." | 9.14 | Double-blind comparison of two types of benzocaine lozenges for the treatment of acute pharyngitis. ( Busch, R; Graubaum, HJ; Grünwald, J; Schmidt, M, 2010) |
| "5 mg benzocaine) provides a rapid analgesic effect and is effective in relieving both severe throat pain as well as difficulty in swallowing associated with acute pharyngitis leading to a 64% improved complete remission within 72 hours." | 5.27 | Efficacy and safety of a triple active sore throat lozenge in the treatment of patients with acute pharyngitis: Results of a multi-centre, randomised, placebo-controlled, double-blind, parallel-group trial (DoriPha). ( Fuchs, K; Milde, J; Palm, J; Schumacher-Stimpfl, A; Stammer, H, 2018) |
| " Eighty-eight patients entered the between-patient study and each completed a diary card covering symptoms experienced and dosage used for each of the two drugs." | 5.26 | Two lozenges containing benzocaine assessed in the relief of sore throat. ( Huddlestone, L; Kagan, G; Wolstencroft, P, 1982) |
| "Benzocaine lozenges are popular in symptomatic treatment of acute sore throat." | 5.16 | Efficacy of a benzocaine lozenge in the treatment of uncomplicated sore throat. ( Beime, B; Chrubasik, S; Magora, F, 2012) |
| "In a reference-controlled double-blind trial in patients with acute pharyngitis the effects of a newly developed lozenge containing 8 mg of benzocaine (p-aminobenzoic acid ethyl ester, CAS 94-09-7) were compared with those of an identically dosed commercial pastille." | 5.14 | Double-blind comparison of two types of benzocaine lozenges for the treatment of acute pharyngitis. ( Busch, R; Graubaum, HJ; Grünwald, J; Schmidt, M, 2010) |
| "A 2-month-old infant developed severe methemoglobinemia following topical pharyngeal application of a common benzocaine containing agent ( Cetacaine )." | 3.67 | Infantile methemoglobinemia induced by a topical anesthetic, Cetacaine. ( Seibert, JJ; Seibert, RW, 1984) |
| " Eighty-eight patients entered the between-patient study and each completed a diary card covering symptoms experienced and dosage used for each of the two drugs." | 1.26 | Two lozenges containing benzocaine assessed in the relief of sore throat. ( Huddlestone, L; Kagan, G; Wolstencroft, P, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Palm, J | 1 |
| Fuchs, K | 1 |
| Stammer, H | 1 |
| Schumacher-Stimpfl, A | 1 |
| Milde, J | 1 |
| Busch, R | 1 |
| Graubaum, HJ | 1 |
| Grünwald, J | 1 |
| Schmidt, M | 1 |
| Chrubasik, S | 1 |
| Beime, B | 1 |
| Magora, F | 1 |
| NOVICK, JM | 1 |
| SODHI, GS | 1 |
| Seibert, RW | 1 |
| Seibert, JJ | 1 |
| Kagan, G | 1 |
| Huddlestone, L | 1 |
| Wolstencroft, P | 1 |
| Janecke, JB | 1 |
| SCHWARTZ, TA | 1 |
| SLASMAN, WH | 1 |
| Halwell, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multi-centre, Randomized, Placebo-controlled, Double-blind, Parallel-group Study Investigating Safety and Efficacy of a Sore Throat Lozenge in the Symptomatic Treatment of Patients With Acute Pharyngitis[NCT03323528] | Phase 4 | 321 participants (Actual) | Interventional | 2017-02-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for benzocaine and Pharyngitis
| Article | Year |
|---|---|
Efficacy and safety of a triple active sore throat lozenge in the treatment of patients with acute pharyngitis: Results of a multi-centre, randomised, placebo-controlled, double-blind, parallel-group trial (DoriPha).
Topics: Acute Disease; Administration, Oral; Adult; Benzalkonium Compounds; Benzocaine; Deglutition; Double- | 2018 |
Double-blind comparison of two types of benzocaine lozenges for the treatment of acute pharyngitis.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Anesthetics, Local; Benzocaine; Chemis | 2010 |
Efficacy of a benzocaine lozenge in the treatment of uncomplicated sore throat.
Topics: Administration, Topical; Adult; Anesthetics, Local; Benzocaine; Double-Blind Method; Female; Humans; | 2012 |
The local anaesthetic effects of cepacaine in post-tonsillectomy cases, pharyngitis and minor infections of the mouth.
Topics: Adult; Anesthetics, Local; Benzocaine; Cetylpyridinium; Clinical Trials as Topic; Dibucaine; Drug Co | 1976 |
5 other studies available for benzocaine and Pharyngitis
| Article | Year |
|---|---|
Evaluation of chloraseptic.
Topics: Analgesics; Analgesics, Non-Narcotic; Anti-Infective Agents, Local; Antipyretics; Benzocaine; Pharyn | 1960 |
Infantile methemoglobinemia induced by a topical anesthetic, Cetacaine.
Topics: 4-Aminobenzoic Acid; Aminobenzoates; Anesthetics, Local; Benzalkonium Compounds; Benzocaine; Cetrimo | 1984 |
Two lozenges containing benzocaine assessed in the relief of sore throat.
Topics: Adult; Benzocaine; Drug Evaluation; Female; Humans; Male; Pharyngitis; Tablets | 1982 |
Evaluation of Chloraseptic, a new topical preparation for relief of sore throat following tonsillectomy.
Topics: Analgesics; Analgesics, Non-Narcotic; Anti-Infective Agents, Local; Antipyretics; Otolaryngology; Ph | 1961 |
Pharyngitis medicamentosa.
Topics: Humans; Nonprescription Drugs; Pharyngitis; Phenols; Respiratory Tract Infections | 1989 |