benzocaine has been researched along with Odontalgia in 13 studies
Benzocaine: A surface anesthetic that acts by preventing transmission of impulses along NERVE FIBERS and at NERVE ENDINGS.
dextran sulfate sodium : An organic sodium salt of dextran sulfate. It induces colitis in mice.
benzocaine : A benzoate ester having 4-aminobenzoic acid as the acid component and ethanol as the alcohol component. A surface anaesthetic, it is used to suppress the gag reflex, and as a lubricant and topical anaesthetic on the larynx, mouth, nasal cavity, respiratory tract, oesophagus, rectum, urinary tract, and vagina.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors evaluated the efficacy and tolerability of 10 percent and 20 percent benzocaine gels compared with those of a vehicle (placebo) gel for the temporary relief of toothache pain." | 9.17 | An evaluation of 10 percent and 20 percent benzocaine gels in patients with acute toothaches: efficacy, tolerability and compliance with label dose administration directions. ( Boynes, SG; Casamassimo, P; Ciancio, SG; Corby, PM; Creighton, P; Gordon, SM; Hersh, EV; Idzik-Starr, C; Jeffers, GE; Kuperstein, AS; Levine, SC; Leyva, R; Mathew, T; Moore, PA; Papas, A; Shibly, O; Stoopler, ET; Turetzky, SN; Wallen, J, 2013) |
| "This pilot study evaluated subject compliance with a proposed OTC label with improved dosing directions for self-application of a 20% benzocaine gel for toothache pain, and assessed the methodology for evaluating efficacy in a future pivotal study of benzocaine gel." | 9.11 | A study of benzocaine gel dosing for toothache. ( DeRossi, SS; Hersh, EV; Secreto, SA; Stoopler, ET, 2005) |
| "In this randomized, double-blind, placebo-controlled clinical trial, the effectiveness and tolerability of a novel intraoral benzocaine patch was evaluated in 60 patients who presented to the Dental School's emergency clinic with spontaneous toothache pain of at least a moderate intensity." | 9.10 | Efficacy and tolerability of an intraoral benzocaine patch in the relief of spontaneous toothache pain. ( Ciarrocca, KN; DeRossi, SS; Ghassemi, A; Hersh, EV; Secreto, SA, 2003) |
| "The purpose of this investigation was to determine the efficacy of benzocaine for temporary relief of toothache." | 9.05 | Efficacy of using benzocaine for temporary relief of toothache. ( Adair, SM; Sveen, OB; Yaekel, M, 1982) |
| "The authors evaluated the efficacy and tolerability of 10 percent and 20 percent benzocaine gels compared with those of a vehicle (placebo) gel for the temporary relief of toothache pain." | 5.17 | An evaluation of 10 percent and 20 percent benzocaine gels in patients with acute toothaches: efficacy, tolerability and compliance with label dose administration directions. ( Boynes, SG; Casamassimo, P; Ciancio, SG; Corby, PM; Creighton, P; Gordon, SM; Hersh, EV; Idzik-Starr, C; Jeffers, GE; Kuperstein, AS; Levine, SC; Leyva, R; Mathew, T; Moore, PA; Papas, A; Shibly, O; Stoopler, ET; Turetzky, SN; Wallen, J, 2013) |
| "This pilot study evaluated subject compliance with a proposed OTC label with improved dosing directions for self-application of a 20% benzocaine gel for toothache pain, and assessed the methodology for evaluating efficacy in a future pivotal study of benzocaine gel." | 5.11 | A study of benzocaine gel dosing for toothache. ( DeRossi, SS; Hersh, EV; Secreto, SA; Stoopler, ET, 2005) |
| "In this randomized, double-blind, placebo-controlled clinical trial, the effectiveness and tolerability of a novel intraoral benzocaine patch was evaluated in 60 patients who presented to the Dental School's emergency clinic with spontaneous toothache pain of at least a moderate intensity." | 5.10 | Efficacy and tolerability of an intraoral benzocaine patch in the relief of spontaneous toothache pain. ( Ciarrocca, KN; DeRossi, SS; Ghassemi, A; Hersh, EV; Secreto, SA, 2003) |
| "The purpose of this investigation was to determine the efficacy of benzocaine for temporary relief of toothache." | 5.05 | Efficacy of using benzocaine for temporary relief of toothache. ( Adair, SM; Sveen, OB; Yaekel, M, 1982) |
| "Methemoglobinemia is a potentially lethal condition which may result from exposure to benzocaine." | 3.77 | Methemoglobinemia secondary to over-the-counter Anbesol. ( Orr, DL; Orr, TM, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Batra, S | 1 |
| Ochani, RK | 1 |
| Asad, A | 1 |
| Hersh, EV | 4 |
| Ciancio, SG | 1 |
| Kuperstein, AS | 1 |
| Stoopler, ET | 2 |
| Moore, PA | 1 |
| Boynes, SG | 1 |
| Levine, SC | 1 |
| Casamassimo, P | 1 |
| Leyva, R | 1 |
| Mathew, T | 1 |
| Shibly, O | 1 |
| Creighton, P | 1 |
| Jeffers, GE | 1 |
| Corby, PM | 1 |
| Turetzky, SN | 1 |
| Papas, A | 1 |
| Wallen, J | 1 |
| Idzik-Starr, C | 1 |
| Gordon, SM | 1 |
| Jeske, AH | 1 |
| Bong, CL | 1 |
| Hilliard, J | 1 |
| Seefelder, C | 1 |
| Orr, TM | 1 |
| Orr, DL | 1 |
| DeRossi, SS | 2 |
| Ciarrocca, KN | 1 |
| Secreto, SA | 2 |
| Ghassemi, A | 1 |
| Darracq, MA | 1 |
| Daubert, GP | 1 |
| Stoltenberg, JL | 1 |
| Osborn, JB | 1 |
| Carlson, JF | 1 |
| Hodges, JS | 1 |
| Michalowicz, BS | 1 |
| Sveen, OB | 1 |
| Yaekel, M | 1 |
| Adair, SM | 1 |
| Cooper, SA | 1 |
| Segal, H | 1 |
| Greene, J | 1 |
| Gilman, CS | 1 |
| Veser, FH | 1 |
| Randall, D | 1 |
| Koike, S | 1 |
| Amano, Y | 1 |
| Yarita, M | 1 |
| Kakinuma, T | 1 |
| Suda, M | 1 |
| Sagiya, T | 1 |
| Saito, Y | 1 |
| Nikura, M | 1 |
| Kobayashi, K | 1 |
| Yamaguchi, N | 1 |
7 trials available for benzocaine and Odontalgia
| Article | Year |
|---|---|
An evaluation of 10 percent and 20 percent benzocaine gels in patients with acute toothaches: efficacy, tolerability and compliance with label dose administration directions.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Benzocaine; Child; Double-Blind Meth | 2013 |
Efficacy and tolerability of an intraoral benzocaine patch in the relief of spontaneous toothache pain.
Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Aged; Analysis of Variance; Anesth | 2003 |
A study of benzocaine gel dosing for toothache.
Topics: Adolescent; Adult; Aged; Anesthetics, Local; Benzocaine; Dental Caries; Dental Restoration Failure; | 2005 |
A preliminary study of intra-pocket topical versus injected anaesthetic for scaling and root planing.
Topics: Adult; Aged; Anesthetics, Local; Benzocaine; Dental Scaling; Epidemiologic Methods; Female; Gels; Hu | 2007 |
Efficacy of using benzocaine for temporary relief of toothache.
Topics: Adolescent; Adult; Aged; Benzocaine; Child, Preschool; Clinical Trials as Topic; Dental Caries; Doub | 1982 |
Analgesic onset time as a measure of topical anesthetic efficacy in spontaneous toothache pain: a pilot study.
Topics: Adult; Analgesia; Benzocaine; Double-Blind Method; Evaluation Studies as Topic; Female; Humans; Male | 1993 |
[Clinical evaluation of new toothache drug "LTA"].
Topics: Adult; Anesthetics, Local; Benzocaine; Child; Clinical Trials as Topic; Dibucaine; Ethanolamines; Eu | 1986 |
6 other studies available for benzocaine and Odontalgia
| Article | Year |
|---|---|
Teething gels: are they worse than we think? - LETTER TO THE EDITOR.
Topics: Anesthetics, Local; Benzocaine; Drug Misuse; Gels; Health Knowledge, Attitudes, Practice; Humans; In | 2019 |
10- and 20-percent benzocaine gels are effective for the temporary relief of toothache and are well-tolerated.
Topics: Anesthetics, Local; Benzocaine; Female; Humans; Male; Toothache | 2013 |
Severe methemoglobinemia from topical benzocaine 7.5% (baby orajel) use for teething pain in a toddler.
Topics: Anesthetics, Local; Benzocaine; Enzyme Inhibitors; Female; Humans; Infant; Methemoglobinemia; Methyl | 2009 |
Methemoglobinemia secondary to over-the-counter Anbesol.
Topics: Administration, Topical; Adult; Anesthetics, Local; Benzocaine; Enzyme Inhibitors; Humans; Male; Met | 2011 |
A cyanotic toddler.
Topics: Anesthetics, Local; Benzocaine; Carbon Monoxide; Child, Preschool; Cyanosis; Humans; Hypoxia; Male; | 2007 |
Methemoglobinemia from a topical oral anesthetic.
Topics: Administration, Topical; Adult; Anesthetics, Local; Antidotes; Benzocaine; Disease-Free Survival; Hu | 1997 |