Page last updated: 2024-10-23

benzocaine and Anesthesia

benzocaine has been researched along with Anesthesia in 26 studies

Benzocaine: A surface anesthetic that acts by preventing transmission of impulses along NERVE FIBERS and at NERVE ENDINGS.
dextran sulfate sodium : An organic sodium salt of dextran sulfate. It induces colitis in mice.
benzocaine : A benzoate ester having 4-aminobenzoic acid as the acid component and ethanol as the alcohol component. A surface anaesthetic, it is used to suppress the gag reflex, and as a lubricant and topical anaesthetic on the larynx, mouth, nasal cavity, respiratory tract, oesophagus, rectum, urinary tract, and vagina.

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research Excerpts

ExcerptRelevanceReference
" In this study, we evaluated the depth and duration of anesthesia in Xenopus laevis after their immersion in 3 doses of etomidate (15, 22."7.88Comparison of Etomidate, Benzocaine, and MS222 Anesthesia with and without Subsequent Flunixin Meglumine Analgesia in African Clawed Frogs ( ( Carroll, GL; Elliott, JJ; Jeffery, ND; Smith, BD; Taylor, MC; Vail, KJ; Vemulapalli, TH, 2018)
" A dose-response relationship between benzocaine and MHb was investigated."5.28Topical anesthetic-induced methemoglobinemia in sheep: a comparison of benzocaine and lidocaine. ( Guertler, AT; Lagutchik, MS; Martin, DG, 1992)
" We compare AIAE rates (coughing, gagging, apnea, airway obstruction, and laryngospasm) in children who received TPA as part of their propofol-based procedural sedation for EGD with those who did not receive TPA."4.31Topical Pharyngeal Anesthesia in Sedated Pediatric Patients Undergoing Esophagogastroduodenoscopy. ( Aljabari, S; El-Halabi, I; Friedman, S; Ohler, A; Tryon, C; Waheed, S, 2023)
" In this study, we evaluated the depth and duration of anesthesia in Xenopus laevis after their immersion in 3 doses of etomidate (15, 22."3.88Comparison of Etomidate, Benzocaine, and MS222 Anesthesia with and without Subsequent Flunixin Meglumine Analgesia in African Clawed Frogs ( ( Carroll, GL; Elliott, JJ; Jeffery, ND; Smith, BD; Taylor, MC; Vail, KJ; Vemulapalli, TH, 2018)
" The objective of this study was to determine the effective concentrations of benzocaine, eugenol, and menthol for achieving anesthesia in Freshwater Angelfish Pterophyllum scalare and to develop induction and recovery response curves for different concentrations of these anesthetics."3.88Efficacy of Benzocaine, Eugenol, and Menthol as Anesthetics for Freshwater Angelfish. ( Boaratti, AZ; Fernandes, JBK; Khan, KU; Mansano, CFM; Nascimento, TMT; Queiroz, DMA; Rodrigues, AT; Romaneli, RS, 2018)
"Stress in response to anesthesia with benzocaine, MS-222, metomidate and isoeugenol was studied in Atlantic salmon (Salmo salar), Atlantic halibut (Hippoglossus hippoglossus), and Atlantic cod (Gadus morhua) with no concomitant stress from handling or confinement in association with anesthesia or sampling."3.76Anesthesia induces stress in Atlantic salmon (Salmo salar), Atlantic cod (Gadus morhua) and Atlantic halibut (Hippoglossus hippoglossus). ( Kiessling, A; Olsen, RE; Samuelsen, OB; Zahl, IH, 2010)
" This study opens perspectives for using nanoformulations prepared with BENZ in aquaculture, allowing reduction of dosage as well as promoting more effective anesthesia and improved interaction with the mucoadhesive system of fish."1.56Potential of mucoadhesive nanocapsules in drug release and toxicology in zebrafish. ( Barros, ALB; Belo, MAA; Borra, RC; Castro, TFD; Charlie-Silva, I; Corrêa Junior, JD; de Melo, NFS; de Menezes, GB; Eto, SF; Feitosa, NM; Fernandes, DC; Fraceto, LF; Fukushima, HCS; Gomes, JMM; Hoyos, DCM; Mattioli, CC; Pierezan, F; Silva, JO, 2020)
" We measured characteristic sedation and recovery times in response to benzocaine, and used them to devise an intermittent dosing regimen consisting of 14."1.46A Dynamic Anesthesia System for Long-Term Imaging in Adult Zebrafish. ( Kwon, RY; Patil, K; Sanders, GE; Watson, CJ; Wynd, BM, 2017)
" A dose-response relationship between benzocaine and MHb was investigated."1.28Topical anesthetic-induced methemoglobinemia in sheep: a comparison of benzocaine and lidocaine. ( Guertler, AT; Lagutchik, MS; Martin, DG, 1992)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199013 (50.00)18.7374
1990's1 (3.85)18.2507
2000's1 (3.85)29.6817
2010's8 (30.77)24.3611
2020's3 (11.54)2.80

Authors

AuthorsStudies
Aljabari, S1
Ohler, A1
Waheed, S1
El-Halabi, I1
Tryon, C1
Friedman, S1
Charlie-Silva, I1
Feitosa, NM1
Gomes, JMM1
Hoyos, DCM1
Mattioli, CC1
Eto, SF1
Fernandes, DC1
Belo, MAA1
Silva, JO1
Barros, ALB1
Corrêa Junior, JD1
de Menezes, GB1
Fukushima, HCS1
Castro, TFD1
Borra, RC1
Pierezan, F1
de Melo, NFS1
Fraceto, LF1
Rodrigues da Silva, GH1
Lemes, JBP1
Geronimo, G1
Freitas de Lima, F1
de Moura, LD1
Carvalho Dos Santos, A1
Carvalho, NS1
Malange, KF1
Breitkreitz, MC1
Parada, CA1
de Paula, E1
Skår, MW1
Haugland, GT1
Powell, MD1
Wergeland, HI1
Samuelsen, OB2
Smith, BD1
Vail, KJ1
Carroll, GL1
Taylor, MC1
Jeffery, ND1
Vemulapalli, TH1
Elliott, JJ1
Romaneli, RS1
Boaratti, AZ1
Rodrigues, AT1
Queiroz, DMA1
Khan, KU1
Nascimento, TMT1
Fernandes, JBK1
Mansano, CFM1
Mayor-Subirana, G1
Yagüe-García, J1
Valmaseda-Castellón, E1
Arnabat-Domínguez, J1
Berini-Aytés, L1
Gay-Escoda, C1
Wynd, BM1
Watson, CJ1
Patil, K1
Sanders, GE1
Kwon, RY1
Zahl, IH1
Kiessling, A1
Olsen, RE1
Heo, GJ1
Shin, G1
Ganzberg, S1
Kramer, KJ1
BAUMANN, J1
PICARD-LEROY, G1
KOHN, J1
RUTTER, AG1
VITALI, M1
DZIACZKOWSKI, I1
MAZEI, AM1
GRAHAM, PA1
MATHUR, SP1
STEINBERG, JB1
ZEPERNICK, RG1
NORCROSS, K1
BERNSTEIN, BM1
RACHET, J1
BUSSON, A1
ARNOUS, J1
REY, M1
Foster, JM1
Forster, ME1
Bedrick, AD1
Banner, W1
Balcom, RJ1
Bifano, EM1
Hakanson, DO1
Guertler, AT1
Lagutchik, MS1
Martin, DG1
Cooper, JE1
Mahaffey, P1
Applebee, K1
Yuwiler, A1
Samuel, D1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Lidocaine With Epinephrine vs. Bupivacaine With Epinephrine as Local Anesthetic Agents in Wide-awake Hand Surgery: an Outcome Study of Patients' Pain Perception.[NCT02315573]61 participants (Actual)Interventional2014-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for benzocaine and Anesthesia

ArticleYear
The use of local anesthetic agents in medicine.
    Dental clinics of North America, 2010, Volume: 54, Issue:4

    Topics: Administration, Topical; Amides; Anesthesia; Anesthesia, Conduction; Anesthesia, Intravenous; Anesth

2010

Trials

1 trial available for benzocaine and Anesthesia

ArticleYear
Anesthetic efficacy of Oraqix® versus Hurricaine® and placebo for pain control during non-surgical periodontal treatment.
    Medicina oral, patologia oral y cirugia bucal, 2014, Mar-01, Volume: 19, Issue:2

    Topics: Adult; Aged; Anesthesia; Anesthetics, Local; Benzocaine; Dental Scaling; Double-Blind Method; Female

2014

Other Studies

24 other studies available for benzocaine and Anesthesia

ArticleYear
Topical Pharyngeal Anesthesia in Sedated Pediatric Patients Undergoing Esophagogastroduodenoscopy.
    Journal of pediatric gastroenterology and nutrition, 2023, 05-01, Volume: 76, Issue:5

    Topics: Airway Obstruction; Anesthesia; Apnea; Benzocaine; Child; Conscious Sedation; Endoscopy, Digestive S

2023
Potential of mucoadhesive nanocapsules in drug release and toxicology in zebrafish.
    PloS one, 2020, Volume: 15, Issue:9

    Topics: Anesthesia; Animals; Aquaculture; Benzocaine; Chitosan; Drug Carriers; Drug Liberation; Gills; Nanoc

2020
Lipid nanoparticles loaded with butamben and designed to improve anesthesia at inflamed tissues.
    Biomaterials science, 2021, May-04, Volume: 9, Issue:9

    Topics: Anesthesia; Animals; Benzocaine; Drug Carriers; Lipids; Nanoparticles; Nanostructures; Particle Size

2021
Development of anaesthetic protocols for lumpfish (Cyclopterus lumpus L.): Effect of anaesthetic concentrations, sea water temperature and body weight.
    PloS one, 2017, Volume: 12, Issue:7

    Topics: Aminobenzoates; Anesthesia; Anesthetics; Animal Welfare; Animals; Behavior, Animal; Benzocaine; Body

2017
Comparison of Etomidate, Benzocaine, and MS222 Anesthesia with and without Subsequent Flunixin Meglumine Analgesia in African Clawed Frogs (
    Journal of the American Association for Laboratory Animal Science : JAALAS, 2018, 03-01, Volume: 57, Issue:2

    Topics: Aminobenzoates; Analgesics; Anesthesia; Anesthetics; Animals; Benzocaine; Clonixin; Etomidate; Pain

2018
Efficacy of Benzocaine, Eugenol, and Menthol as Anesthetics for Freshwater Angelfish.
    Journal of aquatic animal health, 2018, Volume: 30, Issue:3

    Topics: Anesthesia; Anesthetics; Animals; Benzocaine; Cichlids; Dose-Response Relationship, Drug; Eugenol; F

2018
A Dynamic Anesthesia System for Long-Term Imaging in Adult Zebrafish.
    Zebrafish, 2017, Volume: 14, Issue:1

    Topics: Anesthesia; Anesthetics, Local; Animals; Benzocaine; Time-Lapse Imaging; Zebrafish

2017
Anesthesia induces stress in Atlantic salmon (Salmo salar), Atlantic cod (Gadus morhua) and Atlantic halibut (Hippoglossus hippoglossus).
    Fish physiology and biochemistry, 2010, Volume: 36, Issue:3

    Topics: Aminobenzoates; Analysis of Variance; Anesthesia; Animals; Benzocaine; Etomidate; Eugenol; Flounder;

2010
Efficacy of benzocaine as an anaesthetic for Crucian carp (Carassius carassius).
    Veterinary anaesthesia and analgesia, 2010, Volume: 37, Issue:2

    Topics: Anesthesia; Anesthetics, Local; Animals; Benzocaine; Blood Glucose; Body Weight; Carps; Dose-Respons

2010
[Danger in the use of procaine with butyl aminobenzoate in thoracic surgery].
    Le Poumon, 1954, Volume: 10, Issue:2

    Topics: Aminobenzoates; Analgesia; Anesthesia; Anesthesia and Analgesia; Benzocaine; Pain; Pain Management;

1954
Prolonged local analgesia with benzocaine-urethane solution.
    International journal of anesthesia, 1954, Volume: 2, Issue:2

    Topics: Aminobenzoates; Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthetics; Anesthetics, Local; Be

1954
[Experimental and clinical investigations on the anesthetizing properties of anesthesin solutions in urethane].
    Polski tygodnik lekarski, 1957, Apr-29, Volume: 12, Issue:18

    Topics: Aminobenzoates; Analgesia; Anesthesia; Anesthesia and Analgesia; Benzocaine; Pain Management; Uretha

1957
[Treatment of cracked nipples with novocaine blockade and synthomycin emulsion with anesthesin].
    Sovetskaia meditsina, 1958, Volume: 22, Issue:4

    Topics: Aminobenzoates; Anesthesia; Anesthesia, Conduction; Anesthesiology; Benzocaine; Breast Diseases; Chl

1958
Benzocaine-urethane solution in ophthalmology.
    The British journal of ophthalmology, 1958, Volume: 42, Issue:10

    Topics: Aminobenzoates; Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesia, Conduction; Benzocaine;

1958
Ciliary block with benzocaine in painful blind eyes.
    American journal of ophthalmology, 1959, Volume: 47, Issue:6

    Topics: Aminobenzoates; Anesthesia; Anesthesia, Conduction; Benzocaine; Blindness; Eye Movements; Oculomotor

1959
Methemoglobinemia during anesthesia.
    The Journal of pediatrics, 1962, Volume: 61

    Topics: Anesthesia; Anesthesia, Endotracheal; Benzocaine; Cyanosis; Humans; Methemoglobinemia

1962
MINOR CHEST INJURIES.
    The Manchester medical gazette, 1964, Volume: 43

    Topics: Analgesics; Analgesics, Non-Narcotic; Anesthesia; Anesthesia, Local; Antipyretics; Bandages; Benzoca

1964
Cyanosis following use of anesthesin; case report.
    The Review of gastroenterology, 1950, Volume: 17, Issue:2

    Topics: Anesthesia; Anesthesiology; Benzocaine; Cyanosis; Humans

1950
[A new prolonged anesthetic; benzocaine-urethane; its use in proctology].
    Archives des maladies de l'appareil digestif et des maladies de la nutrition, 1950, Volume: 39, Issue:2

    Topics: Anal Canal; Anesthesia; Anesthesiology; Anesthetics; Benzocaine; Colorectal Surgery; Humans; Pruritu

1950
Changes in plasma catecholamine concentration during salinity manipulation and anaesthesia in the hagfish Eptatretus cirrhatus.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2007, Volume: 177, Issue:1

    Topics: Anesthesia; Anesthetics, Local; Animals; Benzocaine; Blood Pressure; Blood Volume; Consciousness; Ep

2007
Alert: perioperative neonatal methemoglobinemia.
    American journal of diseases of children (1960), 1984, Volume: 138, Issue:9

    Topics: Acidosis; Anesthesia; Benzocaine; Female; Fentanyl; Humans; Infant, Newborn; Intraoperative Complica

1984
Topical anesthetic-induced methemoglobinemia in sheep: a comparison of benzocaine and lidocaine.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1992, Volume: 18, Issue:2

    Topics: Administration, Topical; Anesthesia; Animals; Benzocaine; Dose-Response Relationship, Drug; Female;

1992
Anaesthesia of the medicinal leech (Hirudo medicinalis).
    The Veterinary record, 1986, May-24, Volume: 118, Issue:21

    Topics: Anesthesia; Animals; Benzocaine; Carbon Dioxide; Leeches; Lidocaine

1986
Ethyl-m-aminobenzoate (MS-222) anaesthesia in the newt-Effect of D2O, pH and time of day.
    Experientia, 1974, Sep-15, Volume: 30, Issue:9

    Topics: Anesthesia; Animals; Benzocaine; Circadian Rhythm; Deuterium; Drug Synergism; Hydrogen-Ion Concentra

1974