Page last updated: 2024-10-23

benzocaine and Allergic Contact Dermatitis

benzocaine has been researched along with Allergic Contact Dermatitis in 32 studies

Benzocaine: A surface anesthetic that acts by preventing transmission of impulses along NERVE FIBERS and at NERVE ENDINGS.
dextran sulfate sodium : An organic sodium salt of dextran sulfate. It induces colitis in mice.
benzocaine : A benzoate ester having 4-aminobenzoic acid as the acid component and ethanol as the alcohol component. A surface anaesthetic, it is used to suppress the gag reflex, and as a lubricant and topical anaesthetic on the larynx, mouth, nasal cavity, respiratory tract, oesophagus, rectum, urinary tract, and vagina.

Research Excerpts

ExcerptRelevanceReference
" We present a case of allergic contact dermatitis to benzocaine that was detected incidentally by patch testing and highlight the importance of correctly interpreting patch test results when there are concomitant positive reactions."7.79Allergic contact dermatitis to benzocaine: the importance of concomitant positive patch test results. ( González-Rodríguez, AJ; Gutiérrez-Paredes, EM; Jordá-Cuevas, E; Revert Fernández, Á, 2013)
"Allergic contact dermatitis (ACD) to lidocaine is rising in prevalence."3.80Lidocaine contact allergy is becoming more prevalent. ( de Gannes, G; Kossintseva, I; To, D, 2014)
" We present a case of allergic contact dermatitis to benzocaine that was detected incidentally by patch testing and highlight the importance of correctly interpreting patch test results when there are concomitant positive reactions."3.79Allergic contact dermatitis to benzocaine: the importance of concomitant positive patch test results. ( González-Rodríguez, AJ; Gutiérrez-Paredes, EM; Jordá-Cuevas, E; Revert Fernández, Á, 2013)
"Contact sensitization to benzocaine, p-phenylenediamine, and lanolin was found to be associated with the presence of chronic leg ulcers."3.77Contact sensitization to the allergens of European baseline series in patients with chronic leg ulcers. ( Beliauskienė, A; Schnuch, A; Sitkauskienė, B; Uter, W; Valiukevičienė, S, 2011)
"A 43-year-old woman suffered from recurrent localized swellings and an eczematous dermatitis starting 1 day after an injection of lidocaine."3.69Delayed-type hypersensitivity to subcutaneous lidocaine with tolerance to articaine: confirmation by in vivo and in vitro tests. ( Bircher, AJ; Messmer, SL; Rufli, T; Surber, C, 1996)
"Allergic contact dermatitis is the most common adverse reaction caused by topical drugs."1.43Frequency and trends of contact allergy to and iatrogenic contact dermatitis caused by topical drugs over a 25-year period. ( Gilissen, L; Goossens, A, 2016)
"Anogenital dermatoses (AGD) are common and often very distressing."1.33[Anogenital dermatoses--allergic and irritative causative factors. Analysis of IVDK data and review of the literature]. ( Brinkmeier, T; Frosch, PJ; Kügler, K; Uter, W, 2005)
"Allergic contact dermatitis is a common anogenital disease."1.31Allergic contact dermatitis in patients with anogenital complaints. ( Bauer, A; Elsner, P; Geier, J, 2000)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (18.75)18.2507
2000's10 (31.25)29.6817
2010's14 (43.75)24.3611
2020's2 (6.25)2.80

Authors

AuthorsStudies
Feito-Sancho, L1
Arranz-Sánchez, DM1
Vázquez-Contreras, G1
Martín, AS1
Sanz-Sánchez, T1
Miñarro, ÁMG1
Guerrero, NN1
Robaina, AF1
Silvestre Salvador, JF1
Ljubojević Hadžavdić, S1
Gojčeta Burnić, S1
Hadžavdić, A1
Marinović Kulišić, S1
Jurakić Tončić, R1
Sharma, A1
Agarwal, S1
Garg, G1
Pandey, S1
Schwensen, JF1
Johansen, JD3
Veien, NK1
Funding, AT1
Avnstorp, C1
Osterballe, M1
Andersen, KE2
Paulsen, E1
Mortz, CG1
Sommerlund, M1
Danielsen, A1
Andersen, BL1
Thormann, J1
Kristensen, O1
Kristensen, B1
Vissing, S1
Nielsen, NH1
Thyssen, JP2
Søsted, H1
Ryberg, K1
Agner, T1
Bircher, A1
Diepgen, T1
Foti, C3
Giménez-Arnau, A1
Gonçalo, M2
Goossens, A2
Le Coz, C1
Maibach, HI1
Bruze, M1
To, D1
Kossintseva, I1
de Gannes, G1
Schmutz, JL1
Gilissen, L1
Varas-Meis, E1
Fernandez-Canga, P1
Ruiz-Gonzalez, I1
Rodriguez-Prieto, MÁ1
Muratore, L1
Calogiuri, G1
Nettis, E1
Di Leo, E1
Vacca, A1
Sánchez-Guerrero, IM1
Huertas, AJ1
López, MP1
Carreño, A1
Ramírez, M1
Pajarón, M1
Engkilde, K1
Menné, T1
Beliauskienė, A1
Valiukevičienė, S1
Sitkauskienė, B1
Schnuch, A1
Uter, W2
González-Rodríguez, AJ1
Gutiérrez-Paredes, EM1
Revert Fernández, Á1
Jordá-Cuevas, E1
Brinca, A1
Cabral, R1
Warner, N1
Salvaggio, HL1
Zaenglein, AL1
Suda, A1
Yamashita, M1
Tabei, M1
Taguchi, K1
Vohr, HW1
Tsutsui, N1
Suzuki, R1
Kikuchi, K1
Sakaguchi, K1
Mochizuki, K1
Nakamura, K1
Arroyo, MP1
Bonamonte, D1
Antelmi, A1
Conserva, A1
Angelini, G1
Trager, JD1
Kügler, K1
Brinkmeier, T1
Frosch, PJ1
Jovanović, M1
Karadaglić, D1
Brkić, S1
Turchin, I1
Moreau, L1
Warshaw, E1
Sasseville, D1
Viraben, R1
Aquilina, C1
Cambon, L1
Bazex, J1
Placucci, F1
Lorenzi, S1
La Placa, M1
Vincenzi, C1
Bircher, AJ1
Messmer, SL1
Surber, C1
Rufli, T1
Amano, K1
Nakamura, Y1
Higaki, T1
Kato, H1
Kishida, F1
Nakatsuka, I1
Kumar, A1
Freeman, S1
Bauer, A1
Geier, J1
Elsner, P1
Roos, TC1
Merk, HF1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effectiveness of Pre Injection Use of Cryoanesthesia as Compared to Topical Anesthetic Gel in Reducing Pain Perception During Palatal Injections[NCT06165432]Phase 460 participants (Actual)Interventional2021-03-19Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for benzocaine and Allergic Contact Dermatitis

ArticleYear
Contact dermatitis associated with an anti-haemorrhoidal ointment containing ephedrine and benzocaine: Case report and literature review.
    Contact dermatitis, 2023, Volume: 89, Issue:5

    Topics: Anesthetics, Local; Benzocaine; Dermatitis, Allergic Contact; Dermatitis, Irritant; Ephedrine; Human

2023

Other Studies

31 other studies available for benzocaine and Allergic Contact Dermatitis

ArticleYear
Benzocaine-induced systemic contact dermatitis: A case report.
    Contact dermatitis, 2023, Volume: 89, Issue:6

    Topics: Anesthetics, Local; Benzocaine; Dermatitis, Allergic Contact; Humans

2023
Erythema of the penis after use of a latex condom - latex allergy or something else?
    Contact dermatitis, 2018, Volume: 78, Issue:2

    Topics: Adult; Anesthetics, Local; Benzocaine; Condoms; Dermatitis, Allergic Contact; Erythema; Humans; Male

2018
Desire for lasting long in bed led to contact allergic dermatitis and subsequent superficial penile gangrene: a dreadful complication of benzocaine-containing extended-pleasure condom.
    BMJ case reports, 2018, Sep-27, Volume: 2018

    Topics: Adult; Anti-Bacterial Agents; Benzocaine; Condoms; Debridement; Dermatitis, Allergic Contact; Dermat

2018
Occupational contact dermatitis in hairdressers: an analysis of patch test data from the Danish contact dermatitis group, 2002-2011.
    Contact dermatitis, 2014, Volume: 70, Issue:4

    Topics: Acetamides; Adolescent; Adult; Aged; Allergens; Aminophenols; Ammonium Sulfate; Barbering; Benzocain

2014
Patch testing with a textile dye mix--a multicentre study.
    Contact dermatitis, 2014, Volume: 71, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azo Compounds; Benzocaine; Child; Child, Preschool; Derm

2014
Lidocaine contact allergy is becoming more prevalent.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2014, Volume: 40, Issue:12

    Topics: Anesthesia, Local; Benzocaine; British Columbia; Dermatitis, Allergic Contact; Drug Hypersensitivity

2014
[Generalised contact eczema: Care is needed in selecting a lubricant for digital rectal examination].
    Annales de dermatologie et de venereologie, 2015, Volume: 142, Issue:10

    Topics: Aged, 80 and over; Anesthetics, Local; Benzocaine; Conjunctivitis; Dermatitis, Allergic Contact; Dib

2015
Frequency and trends of contact allergy to and iatrogenic contact dermatitis caused by topical drugs over a 25-year period.
    Contact dermatitis, 2016, Volume: 75, Issue:5

    Topics: Administration, Cutaneous; Administration, Topical; Adolescent; Adult; Age Distribution; Aged; Aged,

2016
Residents' corner. sQuiz your knowledge: Perianal dermatitis: an allergic contact dermatitis?
    European journal of dermatology : EJD, 2017, Feb-01, Volume: 27, Issue:1

    Topics: Aged; Anesthetics, Local; Benzocaine; Dermatitis, Allergic Contact; Humans; Male; Patch Tests; Pruri

2017
Contact allergy to benzocaine in a condom.
    Contact dermatitis, 2008, Volume: 59, Issue:3

    Topics: Adult; Anesthetics, Local; Balanitis; Benzocaine; Condoms; Dermatitis, Allergic Contact; Humans; Mal

2008
Angioedema-like allergic contact dermatitis to castor oil.
    Contact dermatitis, 2010, Volume: 62, Issue:5

    Topics: Angioedema; Benzocaine; Castor Oil; Dermatitis, Allergic Contact; Female; Humans; Middle Aged; Pheno

2010
Prevalence of benzocaine and lidocaine patch test sensitivity in Denmark: temporal trends and relevance.
    Contact dermatitis, 2011, Volume: 65, Issue:2

    Topics: Administration, Topical; Anesthetics, Local; Benzocaine; Causality; Denmark; Dermatitis, Allergic Co

2011
Contact sensitization to the allergens of European baseline series in patients with chronic leg ulcers.
    Medicina (Kaunas, Lithuania), 2011, Volume: 47, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Allergens; Benzocaine; Chronic Disease; Dermatitis, Allergic Contact

2011
Allergic contact dermatitis to benzocaine: the importance of concomitant positive patch test results.
    Actas dermo-sifiliograficas, 2013, Volume: 104, Issue:2

    Topics: Anesthetics, Local; Benzocaine; Dermatitis, Allergic Contact; Female; Humans; Middle Aged; Patch Tes

2013
Contact allergy to local anaesthetics-value of patch testing with a caine mix in the baseline series.
    Contact dermatitis, 2013, Volume: 68, Issue:3

    Topics: Adult; Anesthetics, Local; Benzocaine; Cross Reactions; Dermatitis, Allergic Contact; Dibucaine; Fem

2013
JAAD Grand Rounds quiz. An erosive vulvar rash.
    Journal of the American Academy of Dermatology, 2013, Volume: 68, Issue:2

    Topics: Aged; Benzocaine; Dermatitis, Allergic Contact; Exanthema; Female; Humans; Vulvar Diseases

2013
Local lymph node assay with non-radioisotope alternative endpoints.
    The Journal of toxicological sciences, 2002, Volume: 27, Issue:3

    Topics: Allergens; Animals; Benzocaine; Bromodeoxyuridine; Cell Count; Dermatitis, Allergic Contact; Dinitro

2002
Black henna tattoo reaction in a person with sulfonamide and benzocaine drug allergies.
    Journal of the American Academy of Dermatology, 2003, Volume: 48, Issue:2

    Topics: Aged; Benzocaine; Coloring Agents; Cross Reactions; Dermatitis, Allergic Contact; Drug Hypersensitiv

2003
Allergic contact dermatitis to condoms: description of a clinical case and analytical review of current literature.
    Immunopharmacology and immunotoxicology, 2004, Volume: 26, Issue:3

    Topics: Adult; Benzocaine; Condoms; Dermatitis, Allergic Contact; Drug Hypersensitivity; Gels; Genitalia, Ma

2004
What's your diagnosis? Acute vulvar erythema, edema, and pruritus in a young woman.
    Journal of pediatric and adolescent gynecology, 2005, Volume: 18, Issue:4

    Topics: Acute Disease; Adult; Anesthetics, Local; Benzocaine; Dermatitis, Allergic Contact; Drug Hypersensit

2005
[Anogenital dermatoses--allergic and irritative causative factors. Analysis of IVDK data and review of the literature].
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2005, Volume: 3, Issue:12

    Topics: Adult; Anesthetics, Local; Anus Diseases; Benzocaine; Bufexamac; Causality; Clinical Trials as Topic

2005
Contact urticaria and allergic contact dermatitis to lidocaine in a patient sensitive to benzocaine and propolis.
    Contact dermatitis, 2006, Volume: 54, Issue:2

    Topics: Allergens; Benzocaine; Dermatitis, Allergic Contact; Diagnosis, Differential; Female; Hemorrhoids; H

2006
Cross-reactions among parabens, para-phenylenediamine, and benzocaine: a retrospective analysis of patch testing.
    Dermatitis : contact, atopic, occupational, drug, 2006, Volume: 17, Issue:4

    Topics: Anesthetics, Local; Benzocaine; Coloring Agents; Cross Reactions; Dermatitis, Allergic Contact; Fema

2006
Allergic contact dermatitis in HIV-positive patients.
    Contact dermatitis, 1994, Volume: 31, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adult; Benzocaine; Benzothiazoles; Dermatitis, Allergic Contact;

1994
Sensitization to benzocaine on a condom.
    Contact dermatitis, 1996, Volume: 34, Issue:4

    Topics: Adult; Anesthetics, Local; Benzocaine; Condoms; Dermatitis, Allergic Contact; Humans; Male; Patch Te

1996
Delayed-type hypersensitivity to subcutaneous lidocaine with tolerance to articaine: confirmation by in vivo and in vitro tests.
    Contact dermatitis, 1996, Volume: 34, Issue:6

    Topics: Adult; Anesthetics, Local; Benzocaine; Bupivacaine; Carticaine; Cross Reactions; Dermatitis, Allergi

1996
[Clinical study of patients with positive reactions in patch tests with local anesthetics].
    Nihon Ika Daigaku zasshi, 1997, Volume: 64, Issue:2

    Topics: Anesthetics, Local; Benzocaine; Cross Reactions; Dermatitis, Allergic Contact; Dibucaine; Humans; Li

1997
Comparison of sex differences in guinea-pig maximization test for detection of skin-sensitizing potential using OECD recommended positive control sensitizers.
    The Journal of toxicological sciences, 1998, Volume: 23, Issue:2

    Topics: Acrolein; Animals; Benzocaine; Benzothiazoles; Dermatitis, Allergic Contact; Dinitrochlorobenzene; F

1998
Leukoderma following occupational allergic contact dermatitis.
    Contact dermatitis, 1999, Volume: 41, Issue:2

    Topics: Adult; Benzocaine; Dermatitis, Allergic Contact; Dermatitis, Occupational; Dust; Epoxy Resins; Human

1999
Allergic contact dermatitis in patients with anogenital complaints.
    The Journal of reproductive medicine, 2000, Volume: 45, Issue:8

    Topics: Adult; Anesthetics, Local; Anus Diseases; Benzocaine; Dermatitis, Allergic Contact; Dibucaine; Femal

2000
Allergic contact dermatitis from benzocaine ointment during treatment of herpes zoster.
    Contact dermatitis, 2001, Volume: 44, Issue:2

    Topics: Aged; Anesthetics, Local; Benzocaine; Dermatitis, Allergic Contact; Drug Hypersensitivity; Female; H

2001