benzocaine has been researched along with Acute Disease in 13 studies
Benzocaine: A surface anesthetic that acts by preventing transmission of impulses along NERVE FIBERS and at NERVE ENDINGS.
dextran sulfate sodium : An organic sodium salt of dextran sulfate. It induces colitis in mice.
benzocaine : A benzoate ester having 4-aminobenzoic acid as the acid component and ethanol as the alcohol component. A surface anaesthetic, it is used to suppress the gag reflex, and as a lubricant and topical anaesthetic on the larynx, mouth, nasal cavity, respiratory tract, oesophagus, rectum, urinary tract, and vagina.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a reference-controlled double-blind trial in patients with acute pharyngitis the effects of a newly developed lozenge containing 8 mg of benzocaine (p-aminobenzoic acid ethyl ester, CAS 94-09-7) were compared with those of an identically dosed commercial pastille." | 9.14 | Double-blind comparison of two types of benzocaine lozenges for the treatment of acute pharyngitis. ( Busch, R; Graubaum, HJ; Grünwald, J; Schmidt, M, 2010) |
| "5 mg benzocaine) provides a rapid analgesic effect and is effective in relieving both severe throat pain as well as difficulty in swallowing associated with acute pharyngitis leading to a 64% improved complete remission within 72 hours." | 5.27 | Efficacy and safety of a triple active sore throat lozenge in the treatment of patients with acute pharyngitis: Results of a multi-centre, randomised, placebo-controlled, double-blind, parallel-group trial (DoriPha). ( Fuchs, K; Milde, J; Palm, J; Schumacher-Stimpfl, A; Stammer, H, 2018) |
| "In a reference-controlled double-blind trial in patients with acute pharyngitis the effects of a newly developed lozenge containing 8 mg of benzocaine (p-aminobenzoic acid ethyl ester, CAS 94-09-7) were compared with those of an identically dosed commercial pastille." | 5.14 | Double-blind comparison of two types of benzocaine lozenges for the treatment of acute pharyngitis. ( Busch, R; Graubaum, HJ; Grünwald, J; Schmidt, M, 2010) |
| "To determine the efficacy of Auralgan otic solution (combination product of antipyrine, benzocaine, and glycerin) compared with an olive oil placebo in the management of moderate to severe ear pain in children with acute otitis media (AOM)." | 5.08 | Efficacy of Auralgan for treating ear pain in children with acute otitis media. ( Hoberman, A; Paradise, JL; Reynolds, EA; Urkin, J, 1997) |
| "Results of the use of ampicillin, penicillin G and symptomatic therapy in the treatment of acute otitis media in 142 children were compared." | 3.65 | Treatment of acute otitis media: a controlled study of 142 children. ( Jones, RH; Laxdal, OE; Merida, J, 1970) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (38.46) | 18.7374 |
| 1990's | 5 (38.46) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Palm, J | 1 |
| Fuchs, K | 1 |
| Stammer, H | 1 |
| Schumacher-Stimpfl, A | 1 |
| Milde, J | 1 |
| Busch, R | 1 |
| Graubaum, HJ | 1 |
| Grünwald, J | 1 |
| Schmidt, M | 1 |
| Trager, JD | 1 |
| Brown, CM | 1 |
| Levy, SA | 1 |
| Susann, PW | 1 |
| Hoberman, A | 1 |
| Paradise, JL | 1 |
| Reynolds, EA | 1 |
| Urkin, J | 1 |
| Cooper, HA | 1 |
| Woldman, S | 1 |
| Blondet, P | 1 |
| Le Roux, P | 1 |
| Schandelong, A | 1 |
| Legueult, LC | 1 |
| Laine, G | 1 |
| Ferraro, L | 1 |
| Zeichner, S | 1 |
| Greenblott, G | 1 |
| Groeger, JS | 1 |
| Gentile, DA | 1 |
| Laxdal, OE | 1 |
| Merida, J | 1 |
| Jones, RH | 1 |
| Moulton, C | 1 |
| Crawford, R | 1 |
| Ho, SL | 1 |
| Hollinrake, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multi-centre, Randomized, Placebo-controlled, Double-blind, Parallel-group Study Investigating Safety and Efficacy of a Sore Throat Lozenge in the Symptomatic Treatment of Patients With Acute Pharyngitis[NCT03323528] | Phase 4 | 321 participants (Actual) | Interventional | 2017-02-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for benzocaine and Acute Disease
| Article | Year |
|---|---|
Methemoglobinemia caused by benzocaine topical spray.
Topics: Acute Disease; Administration, Topical; Adult; Aerosols; Anesthesia, Local; Anesthetics, Local; Anti | 1997 |
3 trials available for benzocaine and Acute Disease
| Article | Year |
|---|---|
Efficacy and safety of a triple active sore throat lozenge in the treatment of patients with acute pharyngitis: Results of a multi-centre, randomised, placebo-controlled, double-blind, parallel-group trial (DoriPha).
Topics: Acute Disease; Administration, Oral; Adult; Benzalkonium Compounds; Benzocaine; Deglutition; Double- | 2018 |
Double-blind comparison of two types of benzocaine lozenges for the treatment of acute pharyngitis.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Anesthetics, Local; Benzocaine; Chemis | 2010 |
Efficacy of Auralgan for treating ear pain in children with acute otitis media.
Topics: Acute Disease; Adolescent; Adult; Antipyrine; Benzocaine; Child; Child, Preschool; Double-Blind Meth | 1997 |
9 other studies available for benzocaine and Acute Disease
| Article | Year |
|---|---|
What's your diagnosis? Acute vulvar erythema, edema, and pruritus in a young woman.
Topics: Acute Disease; Adult; Anesthetics, Local; Benzocaine; Dermatitis, Allergic Contact; Drug Hypersensit | 2005 |
Methemoglobinemia: life-threatening complication of endoscopy premedication.
Topics: Acute Disease; Adult; Anesthesia, Local; Benzocaine; Endoscopy, Gastrointestinal; Female; Humans; Me | 1994 |
Treating ear pain in children with acute otitis media.
Topics: Acute Disease; Antipyrine; Benzocaine; Child; Drug Combinations; Ear; Earache; Humans; Instillation, | 1998 |
[Methemoglobinemia and acute toxic hemolytic anemia caused by gingival lotion with a benzocaine and resorcinol base].
Topics: Acute Disease; Anemia, Hemolytic; Benzocaine; Drug Combinations; Humans; Hydroxyquinolines; Infant; | 1985 |
Cetacaine-induced acute methemoglobinemia.
Topics: 4-Aminobenzoic Acid; Acute Disease; Aged; Aminobenzoates; Benzalkonium Compounds; Benzocaine; Cetrim | 1988 |
Severe methemoglobinemia induced by a topical teething preparation.
Topics: Acute Disease; Administration, Topical; Ascorbic Acid; Benzocaine; Humans; Infant; Male; Methemoglob | 1987 |
Treatment of acute otitis media: a controlled study of 142 children.
Topics: Acute Disease; Adolescent; Ampicillin; Antipyrine; Aspirin; Benzocaine; Child; Child, Preschool; Hum | 1970 |
Acute laryngeal oedema following self-medication with Chloraseptic.
Topics: Acute Disease; Epinephrine; Female; Humans; Laryngeal Edema; Middle Aged; Phenols; Product Surveilla | 1991 |
Acute epiglottitis and Chloraseptic.
Topics: Acute Disease; Aerosols; Drug Hypersensitivity; Epiglottitis; Female; Humans; Laryngitis; Middle Age | 1989 |