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benzo(a)pyrene and Urinary Bladder Neoplasms

benzo(a)pyrene has been researched along with Urinary Bladder Neoplasms in 11 studies

Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.

Urinary Bladder Neoplasms: Tumors or cancer of the URINARY BLADDER.

Research Excerpts

ExcerptRelevanceReference
"To confirm the relationship between exposure to coal tar pitch volatiles and bladder cancer among primary aluminum production workers, we carried out a case-control study among blue-collar workers who had worked more than 1 year between 1950-1979 in a major plant using mostly the Soderberg process in the Province of Québec."7.69Estimation of risk of developing bladder cancer among workers exposed to coal tar pitch volatiles in the primary aluminum industry. ( Armstrong, B; Brodeur, J; Thériault, G; Tremblay, C, 1995)
"To confirm the relationship between exposure to coal tar pitch volatiles and bladder cancer among primary aluminum production workers, we carried out a case-control study among blue-collar workers who had worked more than 1 year between 1950-1979 in a major plant using mostly the Soderberg process in the Province of Québec."3.69Estimation of risk of developing bladder cancer among workers exposed to coal tar pitch volatiles in the primary aluminum industry. ( Armstrong, B; Brodeur, J; Thériault, G; Tremblay, C, 1995)
"Additionally, we allude to some of the cancer types where there is molecular epidemiological evidence that these agents are aetiological risk factors."2.58Carcinogens and DNA damage. ( Barnes, JL; John, K; Martin, FL; Poirier, MC; Zubair, M, 2018)
"Smoking is a known risk factor for bladder cancer."2.41Pooled analysis and meta-analysis of glutathione S-transferase M1 and bladder cancer: a HuGE review. ( Autrup, H; Bell, DA; Boffetta, P; Branch, RA; Brockmöller, J; Daly, AK; Engel, LS; Garcia-Closas, M; Heckbert, SR; Kalina, I; Kang, D; Katoh, T; Lafuente, A; Lan, Q; Lin, HJ; Marcus, PM; Pfeiffer, R; Romkes, M; Rothman, N; Taioli, E; Taylor, JA; Vineis, P, 2002)
"A number of bladder cancer case-control studies have noted an association with work as a machinist."2.40Oils and cancer. ( Tolbert, PE, 1997)
"We assessed the metabolic profiles in bladder cancer smokers and non-smokers and identified the key alterations in their metabolism."1.46Tobacco-Specific Carcinogens Induce Hypermethylation, DNA Adducts, and DNA Damage in Bladder Cancer. ( Ambati, CR; Berg, S; Bhowmik, SK; Coarfa, C; Degener, S; Donepudi, SR; El-Zein, R; Gödde, D; Gu, F; Jin, F; Kaipparettu, BA; Karanam, B; Kavuri, SM; Kheradmand, F; Krishnapuram, R; Lerner, SP; Lotan, Y; Maity, S; Michailidis, G; Noldus, J; Piyarathna, DWB; Purwaha, P; Putluri, N; Putluri, V; Rajapakshe, K; Roghmann, F; Roth, S; Sreekumar, A; Störkel, S; Terris, MK; Thaiparambil, J; Vantaku, V; von Rundstedt, FC, 2017)
"To compare the dose-response relationships for two common measures of coal tar-derived substances, benzene-soluble material (BSM) and benzo(a)pyrene (BaP), and to evaluate which among these is more strongly related to the health outcomes."1.34Comparison of two indices of exposure to polycyclic aromatic hydrocarbons in a retrospective aluminium smelter cohort. ( Demers, PA; Friesen, MC; Le, ND; Lorenzi, MF; Spinelli, JJ, 2007)
"Benzo(a)pyrene increased neoplasia in the thymus, spleen, stomach, and hematopoietic system after 28 weeks."1.32Tumor profile of novel p53 heterozygous Tg.AC (v-Ha-ras) bitransgenic mice treated with benzo(a)pyrene and fed dietary N-acetyl-L-cysteine (NAC). ( Barrett, JC; French, JE; Honeycutt, HP; Jokinen, MP; Kari, FW; Martin, KR; Quinn, A, 2004)
"In patients with cancers known to be related to smoking, 46% (n = 50) showed higher levels of glutathione S-transferase class mu."1.29Human leukocyte glutathione S-transferase isozyme (class mu) and susceptibility to smoking-related cancers. ( Krishna, TP; Krishnaswamy, K; Soni, MG, 1995)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (36.36)18.2507
2000's4 (36.36)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jin, F1
Thaiparambil, J1
Donepudi, SR1
Vantaku, V1
Piyarathna, DWB1
Maity, S1
Krishnapuram, R1
Putluri, V1
Gu, F1
Purwaha, P1
Bhowmik, SK1
Ambati, CR1
von Rundstedt, FC1
Roghmann, F1
Berg, S1
Noldus, J1
Rajapakshe, K1
Gödde, D1
Roth, S1
Störkel, S1
Degener, S1
Michailidis, G1
Kaipparettu, BA1
Karanam, B1
Terris, MK1
Kavuri, SM1
Lerner, SP1
Kheradmand, F1
Coarfa, C1
Sreekumar, A1
Lotan, Y1
El-Zein, R1
Putluri, N1
Verma, N1
Pink, M1
Boland, S1
Rettenmeier, AW1
Schmitz-Spanke, S1
Barnes, JL1
Zubair, M1
John, K1
Poirier, MC1
Martin, FL1
Engel, LS1
Taioli, E1
Pfeiffer, R1
Garcia-Closas, M1
Marcus, PM1
Lan, Q1
Boffetta, P1
Vineis, P1
Autrup, H1
Bell, DA1
Branch, RA1
Brockmöller, J1
Daly, AK1
Heckbert, SR1
Kalina, I1
Kang, D1
Katoh, T1
Lafuente, A1
Lin, HJ1
Romkes, M1
Taylor, JA1
Rothman, N1
Martin, KR1
Jokinen, MP1
Honeycutt, HP1
Quinn, A1
Kari, FW1
Barrett, JC1
French, JE1
Friesen, MC1
Demers, PA1
Spinelli, JJ1
Lorenzi, MF1
Le, ND1
DeMarini, DM1
Shelton, ML1
Levine, JG1
Soni, MG1
Krishna, TP1
Krishnaswamy, K1
Tremblay, C1
Armstrong, B1
Thériault, G1
Brodeur, J1
Tolbert, PE1
Nersesyan, AK1

Reviews

3 reviews available for benzo(a)pyrene and Urinary Bladder Neoplasms

ArticleYear
Carcinogens and DNA damage.
    Biochemical Society transactions, 2018, 10-19, Volume: 46, Issue:5

    Topics: Amines; Animals; Aristolochic Acids; Benzo(a)pyrene; Carcinogens; Cross-Linking Reagents; Diet; DNA;

2018
Pooled analysis and meta-analysis of glutathione S-transferase M1 and bladder cancer: a HuGE review.
    American journal of epidemiology, 2002, Jul-15, Volume: 156, Issue:2

    Topics: Benzo(a)pyrene; Carcinogens; Case-Control Studies; Confidence Intervals; Europe; Genotype; Glutathio

2002
Oils and cancer.
    Cancer causes & control : CCC, 1997, Volume: 8, Issue:3

    Topics: 2-Naphthylamine; Benzo(a)pyrene; Carcinogens; Chlorine Compounds; Esophageal Neoplasms; Ethanolamine

1997

Other Studies

8 other studies available for benzo(a)pyrene and Urinary Bladder Neoplasms

ArticleYear
Tobacco-Specific Carcinogens Induce Hypermethylation, DNA Adducts, and DNA Damage in Bladder Cancer.
    Cancer prevention research (Philadelphia, Pa.), 2017, Volume: 10, Issue:10

    Topics: Azacitidine; Benzo(a)pyrene; Biomarkers, Tumor; Butanones; Carcinogens; Cell Line, Tumor; Cohort Stu

2017
Benzo[a]pyrene-induced metabolic shift from glycolysis to pentose phosphate pathway in the human bladder cancer cell line RT4.
    Scientific reports, 2017, 08-29, Volume: 7, Issue:1

    Topics: Benzo(a)pyrene; Biomarkers; Cell Line, Tumor; DNA Damage; Energy Metabolism; Glycolysis; Humans; Met

2017
Tumor profile of novel p53 heterozygous Tg.AC (v-Ha-ras) bitransgenic mice treated with benzo(a)pyrene and fed dietary N-acetyl-L-cysteine (NAC).
    Toxicological sciences : an official journal of the Society of Toxicology, 2004, Volume: 81, Issue:2

    Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Antioxidants; Benzo(a)pyrene; Carcinogens; Diet; F

2004
Comparison of two indices of exposure to polycyclic aromatic hydrocarbons in a retrospective aluminium smelter cohort.
    Occupational and environmental medicine, 2007, Volume: 64, Issue:4

    Topics: Air Pollutants, Occupational; Aluminum; Benzene; Benzo(a)pyrene; British Columbia; Cohort Studies; D

2007
Mutation spectrum of cigarette smoke condensate in Salmonella: comparison to mutations in smoking-associated tumors.
    Carcinogenesis, 1995, Volume: 16, Issue:10

    Topics: Alleles; Animals; Base Sequence; Benzo(a)pyrene; Biotransformation; DNA, Bacterial; DNA, Neoplasm; H

1995
Human leukocyte glutathione S-transferase isozyme (class mu) and susceptibility to smoking-related cancers.
    Journal of toxicology and environmental health, 1995, Volume: 46, Issue:1

    Topics: Adult; Animals; Benzo(a)pyrene; Biomarkers; Disease Susceptibility; Female; Glutathione Transferase;

1995
Estimation of risk of developing bladder cancer among workers exposed to coal tar pitch volatiles in the primary aluminum industry.
    American journal of industrial medicine, 1995, Volume: 27, Issue:3

    Topics: Air Pollutants, Occupational; Aluminum; Benzene; Benzo(a)pyrene; Case-Control Studies; Chemical Indu

1995
Re: Biomarker risk assessment and bladder cancer detection in a cohort exposed to benzidine.
    Journal of the National Cancer Institute, 2001, Oct-03, Volume: 93, Issue:19

    Topics: Benzidines; Benzo(a)pyrene; Biomarkers; Carcinogens; Carcinoma, Transitional Cell; Chromosome Aberra

2001