benzo(a)pyrene has been researched along with Pulmonary Fibrosis in 4 studies
Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although pulmonary dosing of large porous particles has been shown to sustain drug delivery for a few days, there are no reports on safety or long term delivery." | 5.39 | Supercritical fluid technology based large porous celecoxib-PLGA microparticles do not induce pulmonary fibrosis and sustain drug delivery and efficacy for several weeks following a single dose. ( Dhanda, DS; Kompella, UB; Mirvish, SS; Tyagi, P, 2013) |
| "B(a)P used at 50 mg/kg b." | 1.62 | Protective Effects of Thymoquinone, an Active Compound of ( Almatroodi, SA; Alsahli, MA; Alzohairy, MA; Khan, AA; Rahmani, AH, 2021) |
| "Although pulmonary dosing of large porous particles has been shown to sustain drug delivery for a few days, there are no reports on safety or long term delivery." | 1.39 | Supercritical fluid technology based large porous celecoxib-PLGA microparticles do not induce pulmonary fibrosis and sustain drug delivery and efficacy for several weeks following a single dose. ( Dhanda, DS; Kompella, UB; Mirvish, SS; Tyagi, P, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alzohairy, MA | 1 |
| Khan, AA | 1 |
| Alsahli, MA | 1 |
| Almatroodi, SA | 1 |
| Rahmani, AH | 1 |
| Dhanda, DS | 1 |
| Tyagi, P | 1 |
| Mirvish, SS | 1 |
| Kompella, UB | 1 |
| Yee, H | 1 |
| Yie, TA | 1 |
| Goldberg, J | 1 |
| Wong, KM | 1 |
| Rom, WN | 1 |
| Woźniak, H | 1 |
| Wiecek, E | 1 |
| Dobrucka, D | 1 |
| Pelc, W | 1 |
| Maciejewska, A | 1 |
| Bielichowska, G | 1 |
| Opalska, B | 1 |
4 other studies available for benzo(a)pyrene and Pulmonary Fibrosis
| Article | Year |
|---|---|
Protective Effects of Thymoquinone, an Active Compound of
Topics: Animals; Antioxidants; Benzo(a)pyrene; Benzoquinones; Cholesterol; DNA Fragmentation; Inflammation; | 2021 |
Supercritical fluid technology based large porous celecoxib-PLGA microparticles do not induce pulmonary fibrosis and sustain drug delivery and efficacy for several weeks following a single dose.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzo(a)pyrene; Bron | 2013 |
Immunohistochemical study of fibrosis and adenocarcinoma in dominant-negative p53 transgenic mice exposed to chrysotile asbestos and benzo(a)pyrene.
Topics: Adenocarcinoma; Animals; Asbestos, Serpentine; Benzo(a)pyrene; Caspase 3; Cytokines; Drug Synergism; | 2008 |
[Evaluation of occupational exposure of workers engaged in mining of rock raw materials in the Sleza massif].
Topics: Air Pollutants, Occupational; Benzo(a)pyrene; Dust; Humans; Magnesium Silicates; Mining; Occupationa | 1991 |