benzo(a)pyrene has been researched along with Porphyrias in 3 studies
Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Porphyrias: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Multiple doses of beta-naphthoflavone to iron-loaded C57BL/10ScSn mice for 6 weeks caused inhibition of hepatic uroporphyrinogen decarboxylase and a porphyria indistinguishable from that previously only reported for polyhalogenated aromatic chemicals." | 3.67 | Polycyclic aromatic hydrocarbons cause hepatic porphyria in iron-loaded C57BL/10 mice: comparison of uroporphyrinogen decarboxylase inhibition with induction of alkoxyphenoxazone dealkylations. ( Francis, JE; Smith, AG, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Morino-Koga, S | 1 |
| Uchi, H | 1 |
| Tsuji, G | 1 |
| Takahara, M | 1 |
| Kajiwara, J | 1 |
| Hirata, T | 1 |
| Furue, M | 1 |
| Merk, H | 1 |
| Bolsen, K | 1 |
| Lissner, R | 1 |
| Goerz, G | 1 |
| Francis, JE | 1 |
| Smith, AG | 1 |
3 other studies available for benzo(a)pyrene and Porphyrias
| Article | Year |
|---|---|
Reduction of CC-chemokine ligand 5 by aryl hydrocarbon receptor ligands.
Topics: Aged; Aged, 80 and over; Animals; Benzo(a)pyrene; Carbazoles; Case-Control Studies; Cell Line; Cells | 2013 |
Hexachlorobenzene alteration of benzo[a]pyrene metabolism in porphyric and non-porphyric rats.
Topics: Animals; Benzo(a)pyrene; Chlorobenzenes; Female; Hexachlorobenzene; Porphyrias; Rats; Rats, Inbred S | 1986 |
Polycyclic aromatic hydrocarbons cause hepatic porphyria in iron-loaded C57BL/10 mice: comparison of uroporphyrinogen decarboxylase inhibition with induction of alkoxyphenoxazone dealkylations.
Topics: Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Carboxy-Lyases; Che | 1987 |