Page last updated: 2024-10-23

benzo(a)pyrene and Porphyria

benzo(a)pyrene has been researched along with Porphyria in 3 studies

Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.

Research Excerpts

ExcerptRelevanceReference
"Multiple doses of beta-naphthoflavone to iron-loaded C57BL/10ScSn mice for 6 weeks caused inhibition of hepatic uroporphyrinogen decarboxylase and a porphyria indistinguishable from that previously only reported for polyhalogenated aromatic chemicals."3.67Polycyclic aromatic hydrocarbons cause hepatic porphyria in iron-loaded C57BL/10 mice: comparison of uroporphyrinogen decarboxylase inhibition with induction of alkoxyphenoxazone dealkylations. ( Francis, JE; Smith, AG, 1987)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Morino-Koga, S1
Uchi, H1
Tsuji, G1
Takahara, M1
Kajiwara, J1
Hirata, T1
Furue, M1
Merk, H1
Bolsen, K1
Lissner, R1
Goerz, G1
Francis, JE1
Smith, AG1

Other Studies

3 other studies available for benzo(a)pyrene and Porphyria

ArticleYear
Reduction of CC-chemokine ligand 5 by aryl hydrocarbon receptor ligands.
    Journal of dermatological science, 2013, Volume: 72, Issue:1

    Topics: Aged; Aged, 80 and over; Animals; Benzo(a)pyrene; Carbazoles; Case-Control Studies; Cell Line; Cells

2013
Hexachlorobenzene alteration of benzo[a]pyrene metabolism in porphyric and non-porphyric rats.
    IARC scientific publications, 1986, Issue:77

    Topics: Animals; Benzo(a)pyrene; Chlorobenzenes; Female; Hexachlorobenzene; Porphyrias; Rats; Rats, Inbred S

1986
Polycyclic aromatic hydrocarbons cause hepatic porphyria in iron-loaded C57BL/10 mice: comparison of uroporphyrinogen decarboxylase inhibition with induction of alkoxyphenoxazone dealkylations.
    Biochemical and biophysical research communications, 1987, Jul-15, Volume: 146, Issue:1

    Topics: Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Carboxy-Lyases; Che

1987