Page last updated: 2024-10-23

benzo(a)pyrene and Pneumonia

benzo(a)pyrene has been researched along with Pneumonia in 13 studies

Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.

Pneumonia: Infection of the lung often accompanied by inflammation.

Research Excerpts

ExcerptRelevanceReference
"The current study aimed to describe pulmonary inflammation during BaP-induced acute lung injury (ALI)."5.72N-acetylcysteine alleviates pulmonary inflammatory response during benzo[a]pyrene-evoked acute lung injury. ( Fu, L; Gao, L; Li, MD; Lv, BB; Tan, ZX; Xiang, HX; Xiang, Y; Xu, DX; Zhang, C; Zhao, H, 2022)
"The current study aimed to describe pulmonary inflammation during BaP-induced acute lung injury (ALI)."1.72N-acetylcysteine alleviates pulmonary inflammatory response during benzo[a]pyrene-evoked acute lung injury. ( Fu, L; Gao, L; Li, MD; Lv, BB; Tan, ZX; Xiang, HX; Xiang, Y; Xu, DX; Zhang, C; Zhao, H, 2022)
"Our results indicate that pulmonary inflammation increased the genotoxicity of B[a]P via inhibition of both phase I and II metabolism."1.46Altered gene expression profiles in the lungs of benzo[a]pyrene-exposed mice in the presence of lipopolysaccharide-induced pulmonary inflammation. ( Arlt, VM; Fijten, RR; Godschalk, RW; Riffo Vasquez, Y; Shi, Q; Spina, D; Van Schooten, FJ, 2017)
"Rutin pretreatment caused a significant reduction in lipid peroxidation and LDH activity; increased glutathione content; restored antioxidant enzyme activity; reduced DNA strand breaks and fragmentation; modulated the expression of inflammatory, and apoptotic markers and restored the histopathological structure."1.43Attenuation of genotoxicity, oxidative stress, apoptosis and inflammation by rutin in benzo(a)pyrene exposed lungs of mice: plausible role of NF-κB, TNF-α and Bcl-2. ( Ali, N; Ali, R; Hasan, SK; Majed, F; Rashid, S; Shahid, A; Sultana, S, 2016)
"We investigated whether pulmonary inflammation alters the genotoxicity of polycyclic aromatic hydrocarbons (PAHs) in the lungs of mice and what mechanisms are involved."1.42Pulmonary Inflammation Impacts on CYP1A1-Mediated Respiratory Tract DNA Damage Induced by the Carcinogenic Air Pollutant Benzo[a]pyrene. ( Arlt, VM; Corbin, C; Frei, E; Godschalk, RW; Krais, AM; Mrizova, I; Phillips, DH; Riffo-Vasquez, Y; Roufosse, CA; Shi, Q; Spina, D; Stiborova, M; van Schooten, FJ, 2015)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (15.38)29.6817
2010's8 (61.54)24.3611
2020's3 (23.08)2.80

Authors

AuthorsStudies
Fan, L1
Li, W1
Ma, J1
Cheng, M1
Xie, L1
Ye, Z1
Xie, Y1
Wang, B1
Yu, L1
Zhou, Y1
Chen, W1
Gao, M1
Zhang, P1
Huang, L1
Shao, H1
Duan, S1
Li, C1
Zhang, Q1
Wang, W1
Wu, Y1
Wang, J1
Liu, H1
Feng, F1
Tajima, H1
Tajiki-Nishino, R1
Watanabe, Y1
Kurata, K1
Fukuyama, T1
Zhao, H1
Fu, L1
Xiang, HX1
Xiang, Y1
Li, MD1
Lv, BB1
Tan, ZX1
Gao, L1
Zhang, C1
Xu, DX1
Shi, Q3
Fijten, RR1
Spina, D3
Riffo Vasquez, Y1
Arlt, VM3
Godschalk, RW2
Van Schooten, FJ3
Krais, AM1
Riffo-Vasquez, Y1
Mrizova, I1
Roufosse, CA1
Corbin, C1
Frei, E1
Stiborova, M1
Phillips, DH1
Haenen, GR1
Maas, L1
Vasquez, YR1
Moonen, E1
Veith, C1
Godschalk, RWL1
Shahid, A2
Ali, R2
Ali, N2
Hasan, SK1
Rashid, S1
Majed, F1
Sultana, S3
Kazim Hasan, S1
Barnwal, P1
Mohammad Afzal, S1
Vafa, A1
Gentner, NJ1
Weber, LP1
Qamar, W1
Khan, AQ1
Khan, R1
Lateef, A1
Tahir, M1
Rehman, MU1
Ali, F1
Podechard, N1
Lecureur, V1
Le Ferrec, E1
Guenon, I1
Sparfel, L1
Gilot, D1
Gordon, JR1
Lagente, V1
Fardel, O1
Garçon, G1
Gosset, P1
Garry, S1
Marez, T1
Hannothiaux, MH1
Shirali, P1

Other Studies

13 other studies available for benzo(a)pyrene and Pneumonia

ArticleYear
Benzo(a)pyrene induces airway epithelial injury through Wnt5a-mediated non-canonical Wnt-YAP/TAZ signaling.
    The Science of the total environment, 2022, Apr-01, Volume: 815

    Topics: Animals; Benzo(a)pyrene; Lung; Lung Injury; Mice; Pneumonia; Wnt Signaling Pathway

2022
Is NLRP3 or NLRP6 inflammasome activation associated with inflammation-related lung tumorigenesis induced by benzo(a)pyrene and lipopolysaccharide?
    Ecotoxicology and environmental safety, 2019, Dec-15, Volume: 185

    Topics: Animals; Benzo(a)pyrene; Cell Transformation, Neoplastic; Inflammasomes; Lipopolysaccharides; Lung;

2019
Activation of aryl hydrocarbon receptor by benzo[a]pyrene increases interleukin 33 expression and eosinophil infiltration in a mouse model of allergic airway inflammation.
    Journal of applied toxicology : JAT, 2020, Volume: 40, Issue:11

    Topics: A549 Cells; Animals; Basic Helix-Loop-Helix Transcription Factors; Benzo(a)pyrene; Chemotaxis, Leuko

2020
N-acetylcysteine alleviates pulmonary inflammatory response during benzo[a]pyrene-evoked acute lung injury.
    Environmental science and pollution research international, 2022, Volume: 29, Issue:3

    Topics: Acetylcysteine; Acute Lung Injury; Animals; Benzo(a)pyrene; Lung; Mice; NF-kappa B; Pneumonia

2022
Altered gene expression profiles in the lungs of benzo[a]pyrene-exposed mice in the presence of lipopolysaccharide-induced pulmonary inflammation.
    Toxicology and applied pharmacology, 2017, 12-01, Volume: 336

    Topics: Animals; Benzo(a)pyrene; Disease Models, Animal; DNA Adducts; Gene Expression Profiling; Gene Regula

2017
Pulmonary Inflammation Impacts on CYP1A1-Mediated Respiratory Tract DNA Damage Induced by the Carcinogenic Air Pollutant Benzo[a]pyrene.
    Toxicological sciences : an official journal of the Society of Toxicology, 2015, Volume: 146, Issue:2

    Topics: Air Pollutants; Animals; Benzo(a)pyrene; Carcinogens; Cytochrome P-450 CYP1A1; DNA Damage; Male; Mic

2015
Inflammation-associated extracellular β-glucuronidase alters cellular responses to the chemical carcinogen benzo[a]pyrene.
    Archives of toxicology, 2016, Volume: 90, Issue:9

    Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Benzo(a)pyrene; Biotransformation; Carcinogen

2016
Attenuation of genotoxicity, oxidative stress, apoptosis and inflammation by rutin in benzo(a)pyrene exposed lungs of mice: plausible role of NF-κB, TNF-α and Bcl-2.
    Journal of complementary & integrative medicine, 2016, Volume: 13, Issue:1

    Topics: Animals; Antioxidants; Apoptosis; Benzo(a)pyrene; Carcinogens; Cyclooxygenase 2; DNA; Hydrogen Perox

2016
Methanolic bark extract of Acacia catechu ameliorates benzo(a)pyrene induced lung toxicity by abrogation of oxidative stress, inflammation, and apoptosis in mice.
    Environmental toxicology, 2017, Volume: 32, Issue:5

    Topics: Acacia; Animals; Antioxidants; Apoptosis; Benzo(a)pyrene; Carcinogens; Caspase 3; Cytoprotection; Gl

2017
Intranasal benzo[a]pyrene alters circadian blood pressure patterns and causes lung inflammation in rats.
    Archives of toxicology, 2011, Volume: 85, Issue:4

    Topics: Administration, Intranasal; Animals; Aorta, Thoracic; Benzo(a)pyrene; Blood Pressure; Carcinogens, E

2011
Benzo(a)pyrene-induced pulmonary inflammation, edema, surfactant dysfunction, and injuries in rats: alleviation by farnesol.
    Experimental lung research, 2012, Volume: 38, Issue:1

    Topics: Alkaline Phosphatase; Animals; Benzo(a)pyrene; Bronchoalveolar Lavage Fluid; Edema; Epithelial Cells

2012
Interleukin-8 induction by the environmental contaminant benzo(a)pyrene is aryl hydrocarbon receptor-dependent and leads to lung inflammation.
    Toxicology letters, 2008, Mar-15, Volume: 177, Issue:2

    Topics: Animals; Benzo(a)pyrene; Bronchoalveolar Lavage Fluid; Cell Movement; Chemotactic Factors; Chromatin

2008
Pulmonary induction of proinflammatory mediators following the rat exposure to benzo(a)pyrene-coated onto Fe2O3 particles.
    Toxicology letters, 2001, Apr-30, Volume: 121, Issue:2

    Topics: Animals; Benzo(a)pyrene; Bronchoalveolar Lavage Fluid; Culture Media; Drug Interactions; Ferric Comp

2001