benzo(a)pyrene has been researched along with Papilloma, Squamous Cell in 57 studies
Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Excerpt | Relevance | Reference |
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"Benzo(a)pyrene increased neoplasia in the thymus, spleen, stomach, and hematopoietic system after 28 weeks." | 1.32 | Tumor profile of novel p53 heterozygous Tg.AC (v-Ha-ras) bitransgenic mice treated with benzo(a)pyrene and fed dietary N-acetyl-L-cysteine (NAC). ( Barrett, JC; French, JE; Honeycutt, HP; Jokinen, MP; Kari, FW; Martin, KR; Quinn, A, 2004) |
"With the onset of metastasis, HABP1 overexpression was confined to metastatic islands, while it disappeared gradually from the surrounding mass." | 1.32 | Differential expression of Hyaluronic Acid Binding Protein 1 (HABP1)/P32/C1QBP during progression of epidermal carcinoma. ( Chowdhury, AR; Datta, K; Ghosh, I; Rajeswari, MR, 2004) |
" Dose-response studies were conducted at low doses in mouse skin by initiation-promotion and repeated application to compare its activity to that of 7,12-dimethylbenz[a]anthracene (DMBA), benzo[a]pyrene (B[a]P), DB[a,l]P-8,9-dihydrodiol and DB[a,l]P-11,12-dihydrodiol." | 1.29 | Tumor-initiating activity and carcinogenicity of dibenzo[a,l]pyrene versus 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene at low doses in mouse skin. ( Cavalieri, EL; Higginbotham, S; Johansson, SL; RamaKrishna, NV; Rogan, EG, 1993) |
"Acetone-, TPA- or BaP-treated animals were used as negative and positive controls, respectively." | 1.28 | Comparative tumor-initiating ability of 7H-dibenzo(c,g)carbazole and dibenz(a,j)acridine in mouse skin. ( Andringa, A; Barkley, W; LaDow, K; Miller, ML; Warshawsky, D, 1992) |
" The tumor incidence exhibited a clear cut dose-response relationship." | 1.27 | The contribution of polycyclic aromatic hydrocarbons to the carcinogenic impact of emission condensate from coal-fired residential furnaces evaluated by topical application to the skin of mice. ( Abel, U; Brune, H; Dettbarn, G; Deutsch-Wenzel, R; Grimmer, G; Misfeld, J; Timm, J, 1984) |
" These results correlated closely with the dose-response relationships for tumor initiation by the two hydrocarbons." | 1.27 | Correlation between formation of a specific hydrocarbon-deoxyribonucleoside adduct and tumor-initiating activity of 7,12-dimethylbenz(a)anthracene and its 9- and 10-monofluoroderivatives in mice. ( DiGiovanni, J; Fisher, EP; Sawyer, TW, 1986) |
" Analyses of dose-response curves suggest (i) CuDIPS preferentially inhibits BP mutagenesis; (ii) the antimutagenic activity of CuDIPS towards DMBA and the cytotoxicity of the copper complex are derived from the DIPS component of the chelate; (iii) the antimutagenic activity of CuDIPS towards BP requires both copper and DIPS; and (iv) DIPS and CuDIPS induced cytotoxicity is required for inhibition of mutagenesis." | 1.27 | Survey of cytotoxicities and antimutagenic and antitumor initiating activities of Cu(II)(3,5-diisopropylsalicylate)2 and its analogs in a keratinocyte-mediated mutation assay and the murine skin multistage carcinogenesis model. ( Colby, AB; Reiners, JJ, 1988) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 23 (40.35) | 18.7374 |
1990's | 22 (38.60) | 18.2507 |
2000's | 9 (15.79) | 29.6817 |
2010's | 3 (5.26) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Qiblawi, S | 1 |
Dhanarasu, S | 1 |
Faris, MA | 1 |
Chen, YL | 1 |
Fang, JH | 1 |
Lai, MD | 1 |
Shan, YS | 1 |
Singh, B | 1 |
Kale, RK | 1 |
Clark, CR | 1 |
Burnett, DM | 1 |
Parker, CM | 1 |
Arp, EW | 1 |
Swanson, MS | 1 |
Minsavage, GD | 1 |
Kriech, AJ | 1 |
Osborn, LV | 1 |
Freeman, JJ | 1 |
Barter, RA | 1 |
Newton, PE | 1 |
Beazley, SL | 1 |
Stewart, CW | 1 |
ROE, FJ | 2 |
HERROLD, KM | 2 |
DUNHAM, LJ | 1 |
MILLER, JF | 1 |
GRANT, GA | 1 |
Martin, KR | 1 |
Jokinen, MP | 1 |
Honeycutt, HP | 1 |
Quinn, A | 1 |
Kari, FW | 1 |
Barrett, JC | 1 |
French, JE | 1 |
Ghosh, I | 1 |
Chowdhury, AR | 1 |
Rajeswari, MR | 1 |
Datta, K | 1 |
Zhang, Z | 1 |
Yao, R | 1 |
Li, J | 1 |
Wang, Y | 1 |
Boone, CW | 1 |
Lubet, RA | 1 |
You, M | 1 |
Gangar, SC | 1 |
Sandhir, R | 1 |
Rai, DV | 1 |
Koul, A | 1 |
Verma, AK | 1 |
Conrad, EA | 1 |
Boutwell, RK | 1 |
Buhler, DR | 2 |
Unlu, F | 1 |
Thakker, DR | 1 |
Slaga, TJ | 3 |
Newman, MS | 1 |
Levin, W | 2 |
Conney, AH | 3 |
Jerina, DM | 3 |
Burns, FJ | 2 |
Albert, RE | 2 |
Buening, MK | 1 |
Wood, AW | 1 |
Chang, RL | 2 |
Agranat, I | 1 |
Rabinovitz, M | 1 |
Mah, HD | 1 |
Hernandez, O | 1 |
Simpson, RB | 1 |
Miller, EC | 1 |
Miller, JA | 2 |
Gensler, H | 1 |
Bowden, GT | 1 |
Beems, RB | 1 |
van Beek, L | 1 |
Grimmer, G | 1 |
Brune, H | 1 |
Deutsch-Wenzel, R | 1 |
Dettbarn, G | 1 |
Misfeld, J | 1 |
Abel, U | 1 |
Timm, J | 1 |
Wunderlich, V | 1 |
Rajewsky, MF | 1 |
Mellert, W | 1 |
Kühborth, B | 1 |
Gembardt, C | 1 |
Munk, R | 1 |
Nakayama, J | 2 |
Urabe, A | 2 |
Terao, H | 2 |
Moon, DC | 2 |
Hori, Y | 2 |
Kinoshita, N | 2 |
Nesnow, S | 2 |
Gold, A | 1 |
Sangaiah, R | 1 |
Colapietro, AM | 1 |
Goodell, AL | 1 |
Smart, RC | 1 |
Sherman, JH | 1 |
Miller, ML | 2 |
Baxter, CS | 1 |
DiGiovanni, J | 3 |
Beltrán, L | 1 |
Rupp, A | 1 |
Harvey, RG | 2 |
Gill, RD | 1 |
Ruggeri, B | 1 |
DiRado, M | 1 |
Zhang, SY | 2 |
Bauer, B | 1 |
Goodrow, T | 2 |
Klein-Szanto, AJ | 2 |
Higginbotham, S | 1 |
RamaKrishna, NV | 1 |
Johansson, SL | 1 |
Rogan, EG | 1 |
Cavalieri, EL | 1 |
Yamada, T | 1 |
Kuwano, H | 1 |
Matsuda, H | 1 |
Sugimachi, K | 1 |
Ishinishi, N | 2 |
Silva, RA | 2 |
Muñoz, SE | 2 |
Guzmán, CA | 1 |
Eynard, AR | 2 |
Evnard, AR | 1 |
Ramesh, G | 2 |
Das, UN | 2 |
Liu, SC | 1 |
Morris, R | 1 |
Deshpande, SS | 1 |
Ingle, AD | 1 |
Maru, GB | 1 |
Culp, SJ | 1 |
Gaylor, DW | 1 |
Sheldon, WG | 1 |
Goldstein, LS | 1 |
Beland, FA | 1 |
Hakura, A | 2 |
Sonoda, J | 2 |
Tsutsui, Y | 2 |
Mikami, T | 2 |
Imade, T | 1 |
Shimada, M | 1 |
Yaguchi, S | 1 |
Yamanaka, M | 1 |
Tomimatsu, M | 1 |
Tsukidate, K | 2 |
Surh, YJ | 1 |
Kim, SG | 1 |
Liem, A | 1 |
Lee, JW | 1 |
Sagami, F | 1 |
Kerns, WD | 1 |
Wei, SJ | 1 |
Merkler, KA | 1 |
Gwynne, M | 1 |
Cui, XX | 1 |
Murthy, B | 1 |
Huang, MT | 1 |
Xie, JG | 1 |
Lu, YP | 1 |
Lou, YR | 1 |
Shimizu, Y | 1 |
Nakatsuru, Y | 1 |
Ichinose, M | 1 |
Takahashi, Y | 1 |
Kume, H | 1 |
Mimura, J | 1 |
Fujii-Kuriyama, Y | 1 |
Ishikawa, T | 1 |
Perez, CA | 1 |
Chen, XG | 1 |
Li, Y | 1 |
Yan, CH | 1 |
Li, LN | 1 |
Han, R | 1 |
Shamberger, RJ | 1 |
Dasgupta, T | 1 |
Banejee, S | 1 |
Yadav, PK | 1 |
Rao, AR | 1 |
Warshawsky, D | 1 |
Barkley, W | 1 |
LaDow, K | 1 |
Andringa, A | 1 |
Yamasaki, H | 1 |
Hollstein, M | 1 |
Martel, N | 1 |
Cabral, JR | 1 |
Galendo, D | 1 |
Tomatis, L | 1 |
Sawyer, TW | 2 |
Fisher, EP | 1 |
Chang, K | 1 |
Reiners, JJ | 1 |
Colby, AB | 1 |
Mehrotra, NK | 1 |
Kumar, S | 1 |
Antony, M | 1 |
Upadhyay, RR | 1 |
Ghanayat, P | 1 |
Benbehani, AN | 1 |
Sanayen, HD | 1 |
Bergman, H | 1 |
Carlson, GP | 1 |
Fossa, AA | 1 |
Morse, MA | 1 |
Weaver, PM | 1 |
DePass, LR | 1 |
Weil, CS | 1 |
Ballantyne, B | 1 |
Lewis, SC | 1 |
Losco, PE | 1 |
Reid, JB | 1 |
Simon, GS | 1 |
Yamamoto, A | 1 |
Hisanaga, A | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Determining Levels of [D10] Phenanthrene Tetraol in Smokers' Urine[NCT01092650] | Phase 1 | 30 participants (Anticipated) | Interventional | 2007-09-30 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
1 trial available for benzo(a)pyrene and Papilloma, Squamous Cell
Article | Year |
---|---|
Chemopreventive Effect of Cardamom (Elettaria cardamomum L.) Against Benzo(α)Pyrene-Induced Forestomach Papillomagenesis in Swiss Albino Mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Benzo(a)pyrene; Elettaria; Glutathione; L- | 2015 |
56 other studies available for benzo(a)pyrene and Papilloma, Squamous Cell
Article | Year |
---|---|
Depletion of CD4(+)CD25(+) regulatory T cells can promote local immunity to suppress tumor growth in benzo[a]pyrene-induced forestomach carcinoma.
Topics: Animals; Antibodies, Monoclonal; Apoptosis; Benzo(a)pyrene; Carcinoma; Cell Proliferation; Female; F | 2008 |
Chemomodulatory effect of Trachyspermum ammi on murine skin and forestomach papillomagenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antioxidants; Apiaceae; Benzo(a) | 2010 |
Asphalt fume dermal carcinogenicity potential: I. dermal carcinogenicity evaluation of asphalt (bitumen) fume condensates.
Topics: Administration, Cutaneous; Air Pollutants, Occupational; Animals; Benzo(a)pyrene; Carcinogenicity Te | 2011 |
Effect of phenanthrene on tumour-initiation by 3,4-benzopyrene.
Topics: Benzo(a)pyrene; Benzopyrenes; Croton Oil; Papilloma; Phenanthrenes | 1962 |
Induction of carcinoma and papilloma of the Syrian hamster by intratracheal instillation of benzo[a]-pyrene.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Bronchi; Carcinoma; Cricetinae; Humans; Mesocricetus; Papillo | 1962 |
THE EFFECTS OF BENZO(A)PYRENE, CIGARETTE SMOKE CONDENSATE AND ATMOSPHERIC POLLUTANTS ON THE RESPIRATORY SYSTEM OF SYRIAN HAMSTERS.
Topics: Air Pollution; Animals; Benzo(a)pyrene; Benzopyrenes; Bronchial Neoplasms; Carcinogens; Carcinoma; C | 1963 |
EFFECT OF THYMECTOMY ON THE INDUCTION OF SKIN TUMOURS BY 3,4-BENZOPYRENE.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Mice; Neoplasm Regression, Spontaneous; Neoplasm | 1963 |
Tumor profile of novel p53 heterozygous Tg.AC (v-Ha-ras) bitransgenic mice treated with benzo(a)pyrene and fed dietary N-acetyl-L-cysteine (NAC).
Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Antioxidants; Benzo(a)pyrene; Carcinogens; Diet; F | 2004 |
Differential expression of Hyaluronic Acid Binding Protein 1 (HABP1)/P32/C1QBP during progression of epidermal carcinoma.
Topics: Animals; Benzo(a)pyrene; Carcinogens; Carcinoma; Disease Progression; Gene Expression Profiling; Gen | 2004 |
Induction of invasive mouse skin carcinomas in transgenic mice with mutations in both H-ras and p53.
Topics: Animals; Benzo(a)pyrene; Carcinogens; Carcinoma, Squamous Cell; Cocarcinogenesis; Female; Genes, p53 | 2005 |
Modulatory effects of Azadirachta indica on benzo(a)pyrene-induced forestomach tumorigenesis in mice.
Topics: Animals; Anticarcinogenic Agents; Azadirachta; Benzo(a)pyrene; Chemoprevention; Female; Incidence; M | 2006 |
Differential effects of retinoic acid and 7,8-benzoflavone on the induction of mouse skin tumors by the complete carcinogenesis process and by the initiation-promotion regimen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzoflavones; Benzop | 1982 |
Metabolism and tumorigenicity of 7-, 8-, 9-, and 10-fluorobenzo(a)pyrenes.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Carcinogens; Female; Mice; Mice, Inbred St | 1982 |
Relationship of benign papillomas to cancer induction in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Dose-Response Relationship, | 1981 |
Fluorine substitution as a probe for the role of the 6-position of benzo[a]pyrene in carcinogenesis.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Female; Liver Neoplasms, Experimental; Lung Neop | 1983 |
Influence of 13-cis-retinoic acid on mouse skin tumor initiation and promotion.
Topics: Animals; Anthralin; Benzo(a)pyrene; Benzopyrenes; Female; Isotretinoin; Methylnitronitrosoguanidine; | 1984 |
Modifying effect of dietary fat on benzo[a]pyrene-induced respiratory tract tumours in hamsters.
Topics: Adenocarcinoma; Adenoma; Animals; Benzo(a)pyrene; Benzopyrenes; Body Weight; Carcinogens; Carcinoma, | 1984 |
The contribution of polycyclic aromatic hydrocarbons to the carcinogenic impact of emission condensate from coal-fired residential furnaces evaluated by topical application to the skin of mice.
Topics: Administration, Topical; Air Pollutants; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinoma, Squamous | 1984 |
"Tumour suppressor gene" concept of carcinogenesis.
Topics: Alleles; Animals; Benzo(a)pyrene; Cell Division; Gene Expression Regulation, Neoplastic; Genes, Tumo | 1995 |
2-year carcinogenicity study in the male NMRI mouse with 2-ethylhexyl acrylate by epicutaneous administration.
Topics: Acrylates; Administration, Cutaneous; Air Pollutants, Occupational; Animals; Benzo(a)pyrene; Carcino | 1994 |
Effects of krestin (PSK) on tumorigenesis induced by two-stage and complete chemical carcinogenesis.
Topics: Adjuvants, Immunologic; Animals; Antibiotics, Antineoplastic; Benzo(a)pyrene; Carcinoma, Squamous Ce | 1994 |
Mouse skin tumor-initiating activity of benz[j]aceanthrylene in SENCAR mice.
Topics: Animals; Benzo(a)pyrene; Carcinogens; Dose-Response Relationship, Drug; Female; Methylcholanthrene; | 1993 |
Characterization of benzo[a]pyrene-initiated mouse skin papillomas for Ha-ras mutations and protein kinase C levels.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Base Sequence; Benzo(a)pyrene; Codon; DNA, Neopl | 1993 |
Dose- and time-dependent expression of transforming growth factor-beta 1 mRNA and protein in mouse epidermis and papillomas after repeated topical application of benzo[a]pyrene.
Topics: Administration, Topical; Animals; Benzo(a)pyrene; Dose-Response Relationship, Drug; Epidermis; Femal | 1993 |
Further analysis of c-Ha-ras mutations in papillomas initiated by several polycyclic aromatic hydrocarbons and papillomas from uninitiated, promoter-treated skin in SENCAR mice.
Topics: Animals; Base Sequence; Benz(a)Anthracenes; Benzo(a)pyrene; Carcinogens; Codon; DNA, Neoplasm; Femal | 1993 |
Benzo[a]pyrene-induced murine skin tumors exhibit frequent and characteristic G to T mutations in the p53 gene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinoma, Squamous Cell; Genes, Tumor Su | 1993 |
Tumor-initiating activity and carcinogenicity of dibenzo[a,l]pyrene versus 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene at low doses in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Carci | 1993 |
Effect of dietary vitamin A on forestomach tumorigenesis during the total and postinitiation stages in mice treated with high- or low-dose benzo(a)pyrene.
Topics: Animals; Benzo(a)pyrene; Carcinogens; Carcinoma, Squamous Cell; Chi-Square Distribution; Food, Forti | 1995 |
Effects of dietary n-3, n-6 and n-9 polyunsaturated fatty acids on benzo(a)pyrene-induced forestomach tumorigenesis in C57BL6J mice.
Topics: Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carcinoma, Squamous Cell; Cod Liver Oil; Corn Oil; | 1995 |
Effect of free fatty acids on two-stage skin carcinogenesis in mice.
Topics: Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carcinogens; Cell Division; Cocarcinogenesis; Crot | 1996 |
Increased expression of G1 cyclins and cyclin-dependent kinases during tumor progression of chemically induced mouse skin neoplasms.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Carcinoma, Squamous Cell; Ce | 1997 |
Inhibitory effects of curcumin-free aqueous turmeric extract on benzo[a]pyrene-induced forestomach papillomas in mice.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Benzo(a)pyrene; Carcinogens; Curcuma; Curcumin; Dose | 1997 |
A comparison of the tumors induced by coal tar and benzo[a]pyrene in a 2-year bioassay.
Topics: Adenoma; Animals; Benzo(a)pyrene; Biological Assay; Carcinoma; Coal Tar; Diet; Female; Industrial Wa | 1998 |
Toxicity profile of benzo[a]pyrene in the male LacZ transgenic mouse (MutaMouse) following oral administration for 5 consecutive days.
Topics: Administration, Oral; Animals; Benzo(a)pyrene; Body Weight; Carcinogenicity Tests; Carcinogens; Carc | 1998 |
Effect of evening primrose and fish oils on two stage skin carcinogenesis in mice.
Topics: Animals; Benzo(a)pyrene; Carcinogens; DNA; Fatty Acids; Fatty Acids, Essential; Fish Oils; gamma-Lin | 1998 |
Inhibitory effects of isopropyl-2-(1,3-dithietane-2-ylidene)-2- [N-(4-methylthiazol-2-yl)carbamoyl]acetate (YH439) on benzo[a]pyrene-induced skin carcinogenesis and micronucleated reticulocyte formation in mice.
Topics: Animals; Anticarcinogenic Agents; Antimutagenic Agents; Antineoplastic Agents; Benzo(a)pyrene; Cross | 1999 |
Multiple organ mutation in the lacZ transgenic mouse (Muta mouse) 6 months after oral treatment (5 days) with benzo[a]pyrene.
Topics: Administration, Oral; Animals; Benzo(a)pyrene; Carcinoma, Squamous Cell; Lac Operon; Lung; Male; Mic | 1999 |
Dose-dependent mutation profile in the c-Ha-ras proto-oncogene of skin tumors in mice initiated with benzo[a]pyrene.
Topics: Administration, Cutaneous; Amino Acid Substitution; Animals; Benzo(a)pyrene; Carcinogens; Carcinoma | 1999 |
Benzo[a]pyrene carcinogenicity is lost in mice lacking the aryl hydrocarbon receptor.
Topics: Animals; Benzo(a)pyrene; Carcinogens; Carcinoma, Squamous Cell; Female; Fibrosarcoma; Gene Expressio | 2000 |
Effects of dietary fat on benz-a-pyrene-induced forestomach tumorigenesis in mice chronically exposed to arsenic.
Topics: Animals; Arsenic; Benzo(a)pyrene; Carcinogens; Dietary Fats; Disease Models, Animal; Drug Interactio | 2000 |
Cancer chemopreventive activities of S-3-1, a synthetic derivative of danshinone.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Benzofurans; Bep | 2001 |
Relationship of selenium to cancer. I. Inhibitory effect of selenium on carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antioxidants; Benzo(a)pyrene; Carci | 1970 |
Chemomodulation of carcinogen metabolising enzymes, antioxidant profiles and skin and forestomach papillomagenesis by Spirulina platensis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Benzo(a)pyrene; Body Weight; Carcinogens; C | 2001 |
Immunohistochemical characterization of cellular infiltrates in epidermal tumors induced by two-stage and complete chemical carcinogenesis in mouse skin.
Topics: Animals; Benzo(a)pyrene; Carcinoma, Squamous Cell; Female; Killer Cells, Natural; Lymphocytes, Tumor | 1992 |
Comparative tumor-initiating ability of 7H-dibenzo(c,g)carbazole and dibenz(a,j)acridine in mouse skin.
Topics: Acetone; Acridines; Animals; Benzo(a)pyrene; Carbazoles; Carcinogens; Female; Mice; Papilloma; Skin; | 1992 |
Mouse skin papillomas as a stage in cancer progression.
Topics: Animals; Benzo(a)pyrene; Cell Division; Cocarcinogenesis; Mice; Papilloma; Skin Neoplasms; Tetradeca | 1989 |
Transplacental induction of a specific mutation in fetal Ha-ras and its critical role in post-natal carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinoma; Cocarcinogenesis; DNA, Neoplas | 1987 |
Correlation between formation of a specific hydrocarbon-deoxyribonucleoside adduct and tumor-initiating activity of 7,12-dimethylbenz(a)anthracene and its 9- and 10-monofluoroderivatives in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenine; Animals; Benzo(a)pyrene; Biotransformation; Carcinogens; | 1986 |
Further investigations into the effect of non-benzo ring bay-region methyl substituents on tumor-initiating activity of polycyclic hydrocarbons.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Carcino | 1987 |
Survey of cytotoxicities and antimutagenic and antitumor initiating activities of Cu(II)(3,5-diisopropylsalicylate)2 and its analogs in a keratinocyte-mediated mutation assay and the murine skin multistage carcinogenesis model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Benzo(a)pyrene; Cell Line; Cell Su | 1988 |
Carcinogenic property of JBO(P) variety of jute batching oil.
Topics: Animals; Benzo(a)pyrene; Carcinogens; Carcinoma, Squamous Cell; Female; Keratoacanthoma; Mice; Miner | 1988 |
Presence of benz(a)pyrene in soil, room dust & in water samples of Azarbaijan Province of Iran & the carcinogenic activity on back skin of NMRI mice.
Topics: Animals; Benzo(a)pyrene; Carcinoma; Dust; Environmental Pollutants; Housing; Iran; Mice; Mice, Inbre | 1987 |
Comparison of the tumorigenic response of SENCAR and C57BL/6 mice to benzo(a)pyrene and the inter-experimental variability over a three-year period.
Topics: Animals; Benzo(a)pyrene; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Male; Mice; M | 1986 |
Binding and distribution studies in the SENCAR mouse of compounds demonstrating a route-dependent tumorigenic effect.
Topics: Acrylamide; Acrylamides; Administration, Oral; Administration, Topical; Animals; Benzo(a)pyrene; Car | 1986 |
Influence of housing conditions for mice on the results of a dermal oncogenicity bioassay.
Topics: Animals; Benzo(a)pyrene; Body Weight; Carcinoma; Dental Cements; Male; Mice; Mice, Inbred C3H; Papil | 1986 |
Comparative study on the carcinogenicity of N-nitrosodiethylamine and benzo[a]pyrene to the lung of Syrian golden hamsters induced by intermittent instillations to the trachea.
Topics: Adenoma; Administration, Topical; Animals; Benzo(a)pyrene; Carcinoma, Squamous Cell; Cricetinae; Die | 1985 |