benzo(a)pyrene has been researched along with Pancreatic Neoplasms in 11 studies
Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "A number of bladder cancer case-control studies have noted an association with work as a machinist." | 2.40 | Oils and cancer. ( Tolbert, PE, 1997) |
| "STZ (65 mg/kg)-induced type 2 diabetes mellitus animals showed reduced plasma BDNF and LXA4 levels (P < 0." | 1.51 | PUFAs, BDNF and lipoxin A4 inhibit chemical-induced cytotoxicity of RIN5F cells in vitro and streptozotocin-induced type 2 diabetes mellitus in vivo. ( Bathina, S; Das, UN, 2019) |
| "Significant elevations in pancreatic cancer risk were found in upper quintiles of MAI, and individual mutagens 2-amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline (DiMeIQx) and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)." | 1.38 | Pancreatic cancer risk: associations with meat-derived carcinogen intake in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO) cohort. ( Anderson, KE; Church, TR; Gross, MD; Kazin, SS; Mabie, JE; Mongin, SJ; Risch, A; Sinha, R; Stolzenberg-Solomon, R; Ziegler, RG, 2012) |
| "Incident cases of pancreatic cancer and hospital controls were prospectively identified and interviewed during the hospital stay." | 1.31 | Risk of pancreatic cancer and occupational exposures in Spain. PANKRAS II Study Group. ( Alguacil, J; Benavides, FG; Bernal, F; Carrato, A; Kauppinen, T; Kogevinas, M; Malats, N; Obiols, J; Partanen, T; Porta, M; Rifà, J, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bathina, S | 1 |
| Das, UN | 1 |
| Wang, Y | 1 |
| Wang, H | 1 |
| Gao, H | 1 |
| Xu, B | 1 |
| Zhai, W | 1 |
| Li, J | 1 |
| Zhang, C | 1 |
| Kang, HJ | 1 |
| Hong, YB | 1 |
| Kim, HJ | 1 |
| Yi, YW | 1 |
| Nath, RG | 1 |
| Chang, YS | 1 |
| Cho, HC | 1 |
| Bae, I | 1 |
| Anderson, KE | 2 |
| Mongin, SJ | 1 |
| Sinha, R | 3 |
| Stolzenberg-Solomon, R | 1 |
| Gross, MD | 1 |
| Ziegler, RG | 1 |
| Mabie, JE | 1 |
| Risch, A | 1 |
| Kazin, SS | 1 |
| Church, TR | 1 |
| Kadlubar, FF | 1 |
| Kulldorff, M | 1 |
| Harnack, L | 1 |
| Gross, M | 1 |
| Lang, NP | 1 |
| Barber, C | 1 |
| Rothman, N | 1 |
| Eguchi, H | 1 |
| Nakachi, K | 1 |
| Li, D | 1 |
| Day, RS | 1 |
| Bondy, ML | 1 |
| Nguyen, NT | 1 |
| Evans, DB | 1 |
| Abbruzzese, JL | 1 |
| Hassan, MM | 1 |
| Trethewie, ER | 1 |
| Van Cauteren, H | 1 |
| Jacqmin, P | 1 |
| Coussement, W | 1 |
| Meuldermans, W | 1 |
| Lampo, A | 1 |
| Lammens, L | 1 |
| Tolbert, PE | 1 |
| Alguacil, J | 1 |
| Kauppinen, T | 1 |
| Porta, M | 1 |
| Partanen, T | 1 |
| Malats, N | 1 |
| Kogevinas, M | 1 |
| Benavides, FG | 1 |
| Obiols, J | 1 |
| Bernal, F | 1 |
| Rifà, J | 1 |
| Carrato, A | 1 |
2 reviews available for benzo(a)pyrene and Pancreatic Neoplasms
| Article | Year |
|---|---|
[Smoking as a risk factor for pancreatic cancer].
Topics: Benzo(a)pyrene; Carcinogens; Cohort Studies; Cytochrome P-450 CYP1A1; Glutathione Transferase; Human | 2006 |
Oils and cancer.
Topics: 2-Naphthylamine; Benzo(a)pyrene; Carcinogens; Chlorine Compounds; Esophageal Neoplasms; Ethanolamine | 1997 |
9 other studies available for benzo(a)pyrene and Pancreatic Neoplasms
| Article | Year |
|---|---|
PUFAs, BDNF and lipoxin A4 inhibit chemical-induced cytotoxicity of RIN5F cells in vitro and streptozotocin-induced type 2 diabetes mellitus in vivo.
Topics: Alloxan; Animals; Arachidonic Acid; Benzo(a)pyrene; Brain-Derived Neurotrophic Factor; Cell Death; C | 2019 |
Elevated expression of TGIF is involved in lung carcinogenesis.
Topics: Animals; Apoptosis; Benzo(a)pyrene; Bronchi; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; G | 2015 |
A novel in vitro pancreatic carcinogenesis model.
Topics: Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; BRCA1 Protein; Carcinogenicity Tests; Carcinogens; Ce | 2011 |
Pancreatic cancer risk: associations with meat-derived carcinogen intake in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO) cohort.
Topics: Aged; Amines; Benzo(a)pyrene; Carcinogens; Colorectal Neoplasms; Cooking; Diet; Early Detection of C | 2012 |
Dietary intake of heterocyclic amines and benzo(a)pyrene: associations with pancreatic cancer.
Topics: Aged; Benzo(a)pyrene; Biogenic Amines; Case-Control Studies; Cooking; Diet; Female; Heterocyclic Com | 2005 |
Dietary mutagen exposure and risk of pancreatic cancer.
Topics: Aged; Analysis of Variance; Benzo(a)pyrene; Case-Control Studies; Cooking; Diet; Female; Humans; Mal | 2007 |
Coffee and the pancreas.
Topics: Benzo(a)pyrene; Benzopyrenes; Coffee; Humans; Pancreatic Neoplasms | 1984 |
Commentary on "Hydroxypropyl cyclodextrins: potential synergism with carcinogens".
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; Benzo(a)pyrene; beta-Cyclodextrins; Bile Acids and Salts | 1997 |
Risk of pancreatic cancer and occupational exposures in Spain. PANKRAS II Study Group.
Topics: Aged; Benzo(a)pyrene; Carcinogens; Case-Control Studies; Coloring Agents; Female; Humans; Incidence; | 2000 |