benzo(a)pyrene has been researched along with Non-alcoholic Fatty Liver Disease in 6 studies
Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Non-alcoholic Fatty Liver Disease: Fatty liver finding without excessive ALCOHOL CONSUMPTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Non-alcoholic fatty liver disease (NAFLD) is a progressive disorder of liver metabolism and has become the most common chronic liver disease worldwide." | 3.01 | Low-dose benzo[a]pyrene exposure induces hepatic lipid deposition through LCMT1/PP2Ac-mediated autophagy inhibition. ( Chen, M; Ding, H; Du, B; Feng, M; Huang, Y; Lan, C; Lei, Y; Li, X; Li, Y; Liang, N; Liao, S; Lu, C; Mo, J; Tang, S; Tang, T; Wang, X; Wu, Y; Zhang, N; Zheng, Z, 2023) |
| "Non-alcoholic fatty liver disease (NAFLD) is a worldwide epidemic for which environmental contaminants are increasingly recognized as important etiological factors." | 1.91 | Transcriptomic analysis in zebrafish larvae identifies iron-dependent mitochondrial dysfunction as a possible key event of NAFLD progression induced by benzo[a]pyrene/ethanol co-exposure. ( Bescher, M; Bucher, S; Chalmel, F; Dupont, A; Evrard, B; Fromenty, B; Huc, L; Imran, M; Lagadic-Gossmann, D; Le Mentec, H; Legrand, A; Podechard, N; Sergent, O; Sparfel, L, 2023) |
| "Nonalcoholic fatty liver disease (NAFLD) is a chronic hepatic disease associated with the excessive accumulation of lipids in the liver." | 1.56 | In vitro and in vivo approaches for identifying the role of aryl hydrocarbon receptor in the development of nonalcoholic fatty liver disease. ( Jiang, HY; Jin, R; Jin, Y; Li, B; Li, DL; Wang, ZH; Xia, HG; Zhu, XY, 2020) |
| "The Western diet contributes to nonalcoholic fatty liver disease (NAFLD) pathogenesis." | 1.48 | Cytochrome P450 1A1 (CYP1A1) protects against nonalcoholic fatty liver disease caused by Western diet containing benzo[a]pyrene in mice. ( Makishima, M; Nebert, DW; Uno, S, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 3 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Imran, M | 1 |
| Chalmel, F | 1 |
| Sergent, O | 2 |
| Evrard, B | 1 |
| Le Mentec, H | 1 |
| Legrand, A | 1 |
| Dupont, A | 1 |
| Bescher, M | 1 |
| Bucher, S | 2 |
| Fromenty, B | 2 |
| Huc, L | 1 |
| Sparfel, L | 1 |
| Lagadic-Gossmann, D | 2 |
| Podechard, N | 1 |
| Li, Y | 1 |
| Liang, N | 1 |
| Tang, T | 1 |
| Zheng, Z | 1 |
| Chen, M | 1 |
| Mo, J | 1 |
| Zhang, N | 1 |
| Liao, S | 1 |
| Lei, Y | 1 |
| Wu, Y | 1 |
| Lan, C | 1 |
| Ding, H | 1 |
| Du, B | 1 |
| Feng, M | 1 |
| Wang, X | 1 |
| Li, X | 2 |
| Huang, Y | 1 |
| Lu, C | 1 |
| Tang, S | 1 |
| Zhu, XY | 1 |
| Xia, HG | 1 |
| Wang, ZH | 1 |
| Li, B | 1 |
| Jiang, HY | 1 |
| Li, DL | 1 |
| Jin, R | 1 |
| Jin, Y | 1 |
| Uno, S | 1 |
| Nebert, DW | 1 |
| Makishima, M | 1 |
| Le Guillou, D | 1 |
| Allard, J | 1 |
| Pinon, G | 1 |
| Begriche, K | 1 |
| Tête, A | 1 |
| Neuschäfer-Rube, F | 1 |
| Schraplau, A | 1 |
| Schewe, B | 1 |
| Lieske, S | 1 |
| Krützfeldt, JM | 1 |
| Ringel, S | 1 |
| Henkel, J | 1 |
| Birkenfeld, AL | 1 |
| Püschel, GP | 1 |
1 review available for benzo(a)pyrene and Non-alcoholic Fatty Liver Disease
| Article | Year |
|---|---|
Low-dose benzo[a]pyrene exposure induces hepatic lipid deposition through LCMT1/PP2Ac-mediated autophagy inhibition.
Topics: Animals; Autophagy; Benzo(a)pyrene; Lipids; Liver; Mice; Non-alcoholic Fatty Liver Disease; Phosphop | 2023 |
5 other studies available for benzo(a)pyrene and Non-alcoholic Fatty Liver Disease
| Article | Year |
|---|---|
Transcriptomic analysis in zebrafish larvae identifies iron-dependent mitochondrial dysfunction as a possible key event of NAFLD progression induced by benzo[a]pyrene/ethanol co-exposure.
Topics: Animals; Benzo(a)pyrene; Ethanol; Heme; Humans; Larva; Mitochondria; Non-alcoholic Fatty Liver Disea | 2023 |
In vitro and in vivo approaches for identifying the role of aryl hydrocarbon receptor in the development of nonalcoholic fatty liver disease.
Topics: Adipogenesis; Animals; Benzo(a)pyrene; Cytochrome P-450 CYP1A1; Estradiol; Estrogens; Female; Lipid | 2020 |
Cytochrome P450 1A1 (CYP1A1) protects against nonalcoholic fatty liver disease caused by Western diet containing benzo[a]pyrene in mice.
Topics: Animals; Benzo(a)pyrene; Bile Acids and Salts; Cytochrome P-450 CYP1A1; Diet, Western; Dietary Expos | 2018 |
Possible Involvement of Mitochondrial Dysfunction and Oxidative Stress in a Cellular Model of NAFLD Progression Induced by Benzo[a]pyrene/Ethanol CoExposure.
Topics: Benzo(a)pyrene; Disease Progression; Ethanol; Humans; Mitochondria; Non-alcoholic Fatty Liver Diseas | 2018 |
Arylhydrocarbon receptor-dependent mIndy (Slc13a5) induction as possible contributor to benzo[a]pyrene-induced lipid accumulation in hepatocytes.
Topics: Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; Benzo(a)pyrene; Carcinogens; Chromatin Immu | 2015 |