benzo(a)pyrene has been researched along with Non-alcoholic Fatty Liver Disease in 6 studies
Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Non-alcoholic Fatty Liver Disease: Fatty liver finding without excessive ALCOHOL CONSUMPTION.
Excerpt | Relevance | Reference |
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"Non-alcoholic fatty liver disease (NAFLD) is a progressive disorder of liver metabolism and has become the most common chronic liver disease worldwide." | 3.01 | Low-dose benzo[a]pyrene exposure induces hepatic lipid deposition through LCMT1/PP2Ac-mediated autophagy inhibition. ( Chen, M; Ding, H; Du, B; Feng, M; Huang, Y; Lan, C; Lei, Y; Li, X; Li, Y; Liang, N; Liao, S; Lu, C; Mo, J; Tang, S; Tang, T; Wang, X; Wu, Y; Zhang, N; Zheng, Z, 2023) |
"Non-alcoholic fatty liver disease (NAFLD) is a worldwide epidemic for which environmental contaminants are increasingly recognized as important etiological factors." | 1.91 | Transcriptomic analysis in zebrafish larvae identifies iron-dependent mitochondrial dysfunction as a possible key event of NAFLD progression induced by benzo[a]pyrene/ethanol co-exposure. ( Bescher, M; Bucher, S; Chalmel, F; Dupont, A; Evrard, B; Fromenty, B; Huc, L; Imran, M; Lagadic-Gossmann, D; Le Mentec, H; Legrand, A; Podechard, N; Sergent, O; Sparfel, L, 2023) |
"Nonalcoholic fatty liver disease (NAFLD) is a chronic hepatic disease associated with the excessive accumulation of lipids in the liver." | 1.56 | In vitro and in vivo approaches for identifying the role of aryl hydrocarbon receptor in the development of nonalcoholic fatty liver disease. ( Jiang, HY; Jin, R; Jin, Y; Li, B; Li, DL; Wang, ZH; Xia, HG; Zhu, XY, 2020) |
"The Western diet contributes to nonalcoholic fatty liver disease (NAFLD) pathogenesis." | 1.48 | Cytochrome P450 1A1 (CYP1A1) protects against nonalcoholic fatty liver disease caused by Western diet containing benzo[a]pyrene in mice. ( Makishima, M; Nebert, DW; Uno, S, 2018) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 3 (50.00) | 24.3611 |
2020's | 3 (50.00) | 2.80 |
Authors | Studies |
---|---|
Imran, M | 1 |
Chalmel, F | 1 |
Sergent, O | 2 |
Evrard, B | 1 |
Le Mentec, H | 1 |
Legrand, A | 1 |
Dupont, A | 1 |
Bescher, M | 1 |
Bucher, S | 2 |
Fromenty, B | 2 |
Huc, L | 1 |
Sparfel, L | 1 |
Lagadic-Gossmann, D | 2 |
Podechard, N | 1 |
Li, Y | 1 |
Liang, N | 1 |
Tang, T | 1 |
Zheng, Z | 1 |
Chen, M | 1 |
Mo, J | 1 |
Zhang, N | 1 |
Liao, S | 1 |
Lei, Y | 1 |
Wu, Y | 1 |
Lan, C | 1 |
Ding, H | 1 |
Du, B | 1 |
Feng, M | 1 |
Wang, X | 1 |
Li, X | 2 |
Huang, Y | 1 |
Lu, C | 1 |
Tang, S | 1 |
Zhu, XY | 1 |
Xia, HG | 1 |
Wang, ZH | 1 |
Li, B | 1 |
Jiang, HY | 1 |
Li, DL | 1 |
Jin, R | 1 |
Jin, Y | 1 |
Uno, S | 1 |
Nebert, DW | 1 |
Makishima, M | 1 |
Le Guillou, D | 1 |
Allard, J | 1 |
Pinon, G | 1 |
Begriche, K | 1 |
Tête, A | 1 |
Neuschäfer-Rube, F | 1 |
Schraplau, A | 1 |
Schewe, B | 1 |
Lieske, S | 1 |
Krützfeldt, JM | 1 |
Ringel, S | 1 |
Henkel, J | 1 |
Birkenfeld, AL | 1 |
Püschel, GP | 1 |
1 review available for benzo(a)pyrene and Non-alcoholic Fatty Liver Disease
Article | Year |
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Low-dose benzo[a]pyrene exposure induces hepatic lipid deposition through LCMT1/PP2Ac-mediated autophagy inhibition.
Topics: Animals; Autophagy; Benzo(a)pyrene; Lipids; Liver; Mice; Non-alcoholic Fatty Liver Disease; Phosphop | 2023 |
5 other studies available for benzo(a)pyrene and Non-alcoholic Fatty Liver Disease
Article | Year |
---|---|
Transcriptomic analysis in zebrafish larvae identifies iron-dependent mitochondrial dysfunction as a possible key event of NAFLD progression induced by benzo[a]pyrene/ethanol co-exposure.
Topics: Animals; Benzo(a)pyrene; Ethanol; Heme; Humans; Larva; Mitochondria; Non-alcoholic Fatty Liver Disea | 2023 |
In vitro and in vivo approaches for identifying the role of aryl hydrocarbon receptor in the development of nonalcoholic fatty liver disease.
Topics: Adipogenesis; Animals; Benzo(a)pyrene; Cytochrome P-450 CYP1A1; Estradiol; Estrogens; Female; Lipid | 2020 |
Cytochrome P450 1A1 (CYP1A1) protects against nonalcoholic fatty liver disease caused by Western diet containing benzo[a]pyrene in mice.
Topics: Animals; Benzo(a)pyrene; Bile Acids and Salts; Cytochrome P-450 CYP1A1; Diet, Western; Dietary Expos | 2018 |
Possible Involvement of Mitochondrial Dysfunction and Oxidative Stress in a Cellular Model of NAFLD Progression Induced by Benzo[a]pyrene/Ethanol CoExposure.
Topics: Benzo(a)pyrene; Disease Progression; Ethanol; Humans; Mitochondria; Non-alcoholic Fatty Liver Diseas | 2018 |
Arylhydrocarbon receptor-dependent mIndy (Slc13a5) induction as possible contributor to benzo[a]pyrene-induced lipid accumulation in hepatocytes.
Topics: Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; Benzo(a)pyrene; Carcinogens; Chromatin Immu | 2015 |