benzo(a)pyrene has been researched along with Neoplasms in 153 studies
Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cancer is believed to arise through the perturbation of pathways and the order of pathway perturbation events can enhance understanding and evaluation of carcinogenicity." | 2.58 | Filling the gap between chemical carcinogenesis and the hallmarks of cancer: A temporal perspective. ( Degli Esposti, D; Demetriou, CA; Pullen Fedinick, K; Robinson, O; Russo, F; Vineis, P, 2018) |
| "Additionally, we allude to some of the cancer types where there is molecular epidemiological evidence that these agents are aetiological risk factors." | 2.58 | Carcinogens and DNA damage. ( Barnes, JL; John, K; Martin, FL; Poirier, MC; Zubair, M, 2018) |
| " We found that toxicogenomics provided rich mechanistic data applicable to hazard identification, dose-response analysis, and quantitative RA of BaP." | 2.52 | Integrating toxicogenomics into human health risk assessment: lessons learned from the benzo[a]pyrene case study. ( Bourdon-Lacombe, J; Buick, JK; Chepelev, NL; Halappanavar, S; Kuo, B; Labib, S; Lemieux, F; Malik, AI; Moffat, ID; Williams, A; Yauk, CL, 2015) |
| " Carcinogenicity studies of coal tar mixtures, considered to be representative of the genotoxic and carcinogenic PAH in food, have been used for dose-response modelling." | 2.46 | Application of the margin-of-exposure (MoE) approach to substances in food that are genotoxic and carcinogenic e.g.: benzo[a]pyrene and polycyclic aromatic hydrocarbons. ( Benford, D; Dinovi, M; Setzer, RW, 2010) |
| "The studies on the etiology of cancer show that 60-90% of human cancer are caused by the carcinogens in ambient environment." | 2.42 | [Environmental carcinogens and p53 gene mutation]. ( Jin, Y; Xu, Z, 2004) |
| "A number of bladder cancer case-control studies have noted an association with work as a machinist." | 2.40 | Oils and cancer. ( Tolbert, PE, 1997) |
| " The guinea pig is the most susceptible mammal known, with an LD50 in the range 1-2 micrograms TCDD/kg, whereas the hamster is the most resistant species with an LD50 greater than 3000 micrograms/kg." | 2.40 | Interspecies differences in cancer susceptibility and toxicity. ( Hengstler, JG; Oesch, F; Steinberg, P; Van der Burg, B, 1999) |
| "Regarding cancer risks, benzo[a]pyrene levels in all the groups indicated a potential risk." | 1.91 | Risk characterization of human exposure to polycyclic aromatic hydrocarbons in vulnerable groups. ( Barbosa, F; Campíglia, AD; Cruz, JC; Domingo, JL; Palir, N; Rocha, BA; Souza, MCO, 2023) |
| "Associated cancer risks following soil ingestion were also evaluated." | 1.51 | In vitro gastrointestinal mobilization and oral bioaccessibility of PAHs in contrasting soils and associated cancer risks: Focus on PAH nonextractable residues. ( Duan, L; Esposito, M; Naidu, R; Semple, KT; Umeh, AC, 2019) |
| "The mean cancer risk for students (3." | 1.48 | Assessment of Polycyclic Aromatic Hydrocarbons in School Playground Soils in Urban Gwangju, South Korea. ( Chung, SY; Islam, MN; Jo, YT; Park, JH, 2018) |
| "Lack of observed malignancy might be explained by the fact that tattooing is only a single dose exposure." | 1.46 | Search for Internal Cancers in Mice Tattooed with Inks of High Contents of Potential Carcinogens: A One-Year Autopsy Study of Red and Black Tattoo Inks Banned in the Market. ( Hutton Carlsen, K; Lerche, CM; Sepehri, M; Serup, J, 2017) |
| "The incremental lifetime cancer risk (ILCR) exposed to particulate PAHs ranged from 10(-4) to 10(-3) indicating high potential of carcinogenic risk, and the ILCR exposed to soil PAHs was from 10(-7) to 10(-6) indicating virtual safety." | 1.42 | Polycyclic aromatic hydrocarbons associated with total suspended particles and surface soils in Kunming, China: distribution, possible sources, and cancer risks. ( Chen, R; Huang, B; Li, X; Lin, C; Pan, X; Ren, D; Sun, W; Yang, X, 2015) |
| "Bladder cancer incidence was not increased at B(a)P exposures below 40 μg/m·yr." | 1.40 | Mortality and cancer incidence in aluminum smelter workers: a 5-year update. ( Busque, MA; Duguay, P; Gibbs, GW; Labrèche, F, 2014) |
| "Genetic mutations are known to drive cancer progression and certain tumors have mutation signatures that reflect exposures to environmental carcinogens." | 1.40 | Exome-wide mutation profile in benzo[a]pyrene-derived post-stasis and immortal human mammary epithelial cells. ( Futscher, BW; Severson, PL; Stampfer, MR; Vrba, L, 2014) |
| "The index of additive cancer risk (IACR) values in almost one third of urban soil samples were more than the safe value of 1." | 1.39 | Polycyclic aromatic hydrocarbons (PAHs) in urban soils of the megacity Shanghai: occurrence, source apportionment and potential human health risk. ( Li, YC; Miao, Y; Wang, XT; Wu, MH; Yu, G; Zhang, Y, 2013) |
| "In this study, cancer and noncancer human health risks from exposure to (PAHs) in street dust in the Tamale metropolis, Ghana were assessed in accordance with the USEPA risk assessment guidelines." | 1.39 | Assessment of cancer and noncancer health risks from exposure to PAHs in street dust in the Tamale Metropolis, Ghana. ( Armah, FA; Cobbina, SJ; Luginaah, I; Obiri, S, 2013) |
| "T-16HBE-C1∼5 cells can form tumors subcutaneously in nude mice." | 1.38 | In vitro malignant transformation of human bronchial epithelial cells induced by benzo(a)pyrene. ( Fu, J; Hao, W; Li, Z; Mi, L; Shang, L; Song, Y; Yao, B; Zhao, P; Zhou, Z, 2012) |
| "Finally, lifetime cancer risk via inhalation of indoor particulate PAHs may be greater than the cancer risk guideline value (10(-6)), depending on specific assumptions used in this risk assessment." | 1.38 | Calculated respiratory exposure to indoor size-fractioned polycyclic aromatic hydrocarbons in an urban environment. ( Li, SM; Wong, CS; Zeng, EY; Zhang, BZ; Zhang, K, 2012) |
| "Cancer is a multistep process characterized by altered signal transduction, cell growth, and metabolism." | 1.36 | Information-theoretic analysis of phenotype changes in early stages of carcinogenesis. ( Kravchenko-Balasha, N; Levine, RD; Levitzki, A; Remacle, F, 2010) |
| "For melting shop workers, cancer risks from exposure to dioxins and PCBs ranged from 2." | 1.35 | Exposure assessment of workers to airborne PCDD/Fs, PCBs and PAHs at an electric arc furnace steelmaking plant in the UK. ( Anderson, DR; Aries, E; Fisher, R, 2008) |
| "The dietary BaP-related cancer risk using carcinogenic potency factor of BaP as 7." | 1.34 | Dietary exposure estimation of benzo[a]pyrene and cancer risk assessment. ( Lee, BM; Shim, GA, 2007) |
| "Cancer is a complex, multi-step process characterized by misregulated signal transduction and altered metabolism." | 1.34 | Optimization of energy-consuming pathways towards rapid growth in HPV-transformed cells. ( Ben-Bassat, H; Klein, S; Kravchenko-Balasha, N; Levitzki, A; Mizrachy-Schwartz, S, 2007) |
| "In contrast with the lack of lung tumors in controls, MCS-exposed mice developed microscopically detectable tumors, starting only 75 days after birth and reaching an overall incidence of 78." | 1.34 | Potent carcinogenicity of cigarette smoke in mice exposed early in life. ( Balansky, R; D'Agostini, F; De Flora, S; Ganchev, G; Iltcheva, M; Steele, VE, 2007) |
| "SIRs from lung cancer have greatly diminished whereas bladder cancer SIRs remain elevated in all but one cohort." | 1.34 | Mortality and cancer experience of Quebec aluminum reduction plant workers, part 4: cancer incidence. ( Gibbs, GW; Sevigny, M, 2007) |
| "This in vitro cancer model can be used as a valuable model in the study of breast carcinogenesis." | 1.33 | Oncoprotein expression and morphological phenotypes of human breast epithelial cells transformed by the c-Ha-ras oncogene. ( Alvarado, ME; Calaf, GM; Hei, TK, 2005) |
| "Total cancer risk across agencies varied by two orders of magnitude, with exposure to air and plant and animal products contributing most to total cancer risk, while the air contribution showed the greatest variability (1-99%)." | 1.33 | An interagency comparison of screening-level risk assessment approaches. ( Diamond, ML; Jones-Otazo, HA; Richardson, GM, 2005) |
| " Based in part on the emerging benchmark dose (BMD) method, the modified BMD method we used involves applying a suite of conventional mathematical models to tumor dose-response data." | 1.32 | Application of benzo(a)pyrene and coal tar tumor dose-response data to a modified benchmark dose method of guideline development. ( Fitzgerald, DJ; Pester, BA; Robinson, NI, 2004) |
| "Benzo(a)pyrene increased neoplasia in the thymus, spleen, stomach, and hematopoietic system after 28 weeks." | 1.32 | Tumor profile of novel p53 heterozygous Tg.AC (v-Ha-ras) bitransgenic mice treated with benzo(a)pyrene and fed dietary N-acetyl-L-cysteine (NAC). ( Barrett, JC; French, JE; Honeycutt, HP; Jokinen, MP; Kari, FW; Martin, KR; Quinn, A, 2004) |
| " A "relative risk index" (RRI) was developed to account for the combined effects of compound-specific bioavailability and toxic potency in estimating excess cancer risk." | 1.32 | Combined effects of contaminant desorption and toxicity on risk from PAH contaminated sediments. ( Kosson, DS; Rockne, KJ; Shor, LM; Taghon, GL; Young, LY, 2004) |
| " The dose-response relationship between biomarker and exposure dose was further incorporated into a dose-tumor response equation, obtained from 2-yr bioassay, to predict cancer risk." | 1.31 | A proposed methodology of cancer risk assessment modeling using biomarkers. ( Kim, S; Lee, BM; Yoo, SD, 2002) |
| "The traditional multistage (MS) model of carcinogenesis implies several empirically testable properties for dose-response functions." | 1.29 | An exact analysis of the multistage model explaining dose-response concavity. ( Cox, LA, 1995) |
| "In patients with cancers known to be related to smoking, 46% (n = 50) showed higher levels of glutathione S-transferase class mu." | 1.29 | Human leukocyte glutathione S-transferase isozyme (class mu) and susceptibility to smoking-related cancers. ( Krishna, TP; Krishnaswamy, K; Soni, MG, 1995) |
| "Incidence of cancer in a cohort of 8391 members of the Finnish Locomotive Drivers' Association, 1953-91, was analysed." | 1.29 | Past exposure to asbestos and combustion products and incidence of cancer among Finnish locomotive drivers. ( Nokso-Koivisto, P; Pukkala, E, 1994) |
| "The excess cancer risk estimates for food ingestion were consistently greater than those for personal air, reflecting both the predominantly higher BaP exposures through the diet and the higher carcinogenic potency value for oral exposure." | 1.29 | Assessment of carcinogenic risk from personal exposure to benzo(a)pyrene in the Total Human Environmental Exposure Study (THEES). ( Butler, JP; Greenberg, A; Lioy, PJ; Post, GB; Waldman, JM, 1993) |
| "Mortality and cancer incidence were investigated among 901 workers at a Swedish company manufacturing graphite electrodes." | 1.29 | Surveillance of mortality and cancer incidence among Swedish graphite electrode workers. ( Bellander, T; Gustavsson, P; Johansson, L; Salmonsson, S, 1995) |
| "The author discussed problems arising from the use of different mathematical dose-response models for extrapolation of cancer risk from high to low doses." | 1.29 | [Methods of extrapolating risk from from high to low doses and their effect on determining MAC values]. ( Szymczak, W, 1996) |
| "In lung and liver cancers, p53 mutations are mostly G:C to T:A transversions." | 1.28 | Selective targeting of p53 gene mutational hotspots in human cancers by etiologically defined carcinogens. ( Groopman, J; Lim, S; Ozturk, M; Puisieux, A, 1991) |
| "In the case of low-risk cancer agents, the examination of potential exposure should follow a sequence that prioritizes the major media and routes of concern." | 1.28 | Exposure analysis and assessment for low-risk cancer agents. ( Lioy, PJ, 1990) |
| " The tumor incidence exhibited a clear cut dose-response relationship." | 1.27 | The contribution of polycyclic aromatic hydrocarbons to the carcinogenic impact of emission condensate from coal-fired residential furnaces evaluated by topical application to the skin of mice. ( Abel, U; Brune, H; Dettbarn, G; Deutsch-Wenzel, R; Grimmer, G; Misfeld, J; Timm, J, 1984) |
| "A large proportion of cancers are initiated by environmental factors which should be discoverable and removable." | 1.27 | The 1984 Association Lecture of the Hospital Physicists' Association. Man and his environment. ( Fremlin, JH, 1985) |
| "This work is a graphical study of all known dose-response data for neoplasia induced by B(a)P, benzene, benzidine, and chromium administered to test animals." | 1.27 | Animal studies and prediction of human tumors can be aided by graphical sorting of animal data: neoplastic risk from B(a)P, benzene, benzidine, and chromium. ( Jones, TD; Walsh, PJ, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 52 (33.99) | 18.7374 |
| 1990's | 25 (16.34) | 18.2507 |
| 2000's | 36 (23.53) | 29.6817 |
| 2010's | 32 (20.92) | 24.3611 |
| 2020's | 8 (5.23) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, R | 1 |
| Elf, S | 1 |
| Shan, C | 1 |
| Kang, HB | 1 |
| Ji, Q | 1 |
| Zhou, L | 1 |
| Hitosugi, T | 1 |
| Zhang, L | 1 |
| Zhang, S | 1 |
| Seo, JH | 1 |
| Xie, J | 1 |
| Tucker, M | 1 |
| Gu, TL | 1 |
| Sudderth, J | 1 |
| Jiang, L | 1 |
| Mitsche, M | 1 |
| DeBerardinis, RJ | 1 |
| Wu, S | 1 |
| Li, Y | 1 |
| Mao, H | 1 |
| Chen, PR | 1 |
| Wang, D | 1 |
| Chen, GZ | 1 |
| Hurwitz, SJ | 1 |
| Lonial, S | 1 |
| Arellano, ML | 1 |
| Khoury, HJ | 1 |
| Khuri, FR | 1 |
| Lee, BH | 1 |
| Lei, Q | 1 |
| Brat, DJ | 1 |
| Ye, K | 1 |
| Boggon, TJ | 1 |
| He, C | 1 |
| Kang, S | 1 |
| Fan, J | 1 |
| Chen, J | 2 |
| Mohammed, AB | 1 |
| Goran, SMA | 1 |
| Tarafdar, A | 1 |
| Zarei, R | 1 |
| Moghadam, D | 1 |
| Sarabi, MM | 1 |
| Naghibalhossaini, F | 1 |
| Lagunas-Rangel, FA | 1 |
| Liu, W | 1 |
| Schiöth, HB | 1 |
| Souza, MCO | 1 |
| Rocha, BA | 1 |
| Cruz, JC | 1 |
| Palir, N | 1 |
| Campíglia, AD | 1 |
| Domingo, JL | 1 |
| Barbosa, F | 1 |
| Umeh, AC | 1 |
| Duan, L | 1 |
| Naidu, R | 1 |
| Esposito, M | 1 |
| Semple, KT | 1 |
| Sharma, D | 1 |
| Jain, S | 1 |
| Km, E | 1 |
| C, H | 1 |
| Mj, K | 1 |
| Gc, P | 1 |
| Ka, K | 1 |
| Gao, M | 1 |
| Zheng, A | 1 |
| Chen, L | 1 |
| Dang, F | 1 |
| Liu, X | 1 |
| Gao, J | 1 |
| Li, L | 1 |
| Wang, Y | 2 |
| Zhou, C | 1 |
| Ma, X | 1 |
| Fu, J | 3 |
| Yao, B | 3 |
| Zhao, P | 3 |
| Sepehri, M | 1 |
| Lerche, CM | 1 |
| Hutton Carlsen, K | 1 |
| Serup, J | 1 |
| Jia, Y | 1 |
| Yan, L | 1 |
| Hao, M | 1 |
| Chen, W | 1 |
| Zhou, Z | 2 |
| Srivastava, P | 1 |
| Sreekrishnan, TR | 1 |
| Nema, AK | 1 |
| Islam, MN | 1 |
| Jo, YT | 1 |
| Chung, SY | 1 |
| Park, JH | 1 |
| Shi, Q | 1 |
| Godschalk, RWL | 1 |
| van Schooten, FJ | 1 |
| Demetriou, CA | 1 |
| Degli Esposti, D | 1 |
| Pullen Fedinick, K | 1 |
| Russo, F | 1 |
| Robinson, O | 1 |
| Vineis, P | 1 |
| Barnes, JL | 1 |
| Zubair, M | 1 |
| John, K | 1 |
| Poirier, MC | 2 |
| Martin, FL | 1 |
| Jakobsen, LS | 1 |
| Georgiadis, S | 1 |
| Nielsen, BF | 1 |
| Bokkers, BGH | 1 |
| Boriani, E | 1 |
| Duedahl-Olesen, L | 1 |
| Hald, T | 1 |
| Nauta, MJ | 1 |
| Stockmarr, A | 1 |
| Pires, SM | 1 |
| Lagadic-Gossmann, D | 1 |
| Hardonnière, K | 1 |
| Mograbi, B | 1 |
| Sergent, O | 1 |
| Huc, L | 1 |
| Gibbs, GW | 2 |
| Labrèche, F | 1 |
| Busque, MA | 1 |
| Duguay, P | 1 |
| Yang, X | 1 |
| Ren, D | 1 |
| Sun, W | 1 |
| Li, X | 1 |
| Huang, B | 1 |
| Chen, R | 1 |
| Lin, C | 1 |
| Pan, X | 1 |
| Severson, PL | 1 |
| Vrba, L | 1 |
| Stampfer, MR | 1 |
| Futscher, BW | 1 |
| Chepelev, NL | 1 |
| Moffat, ID | 1 |
| Labib, S | 1 |
| Bourdon-Lacombe, J | 1 |
| Kuo, B | 1 |
| Buick, JK | 1 |
| Lemieux, F | 1 |
| Malik, AI | 1 |
| Halappanavar, S | 1 |
| Williams, A | 1 |
| Yauk, CL | 1 |
| Perera, RT | 1 |
| Fleming, AM | 1 |
| Johnson, RP | 1 |
| Burrows, CJ | 1 |
| White, HS | 1 |
| Lee, JW | 1 |
| Won, EJ | 1 |
| Raisuddin, S | 1 |
| Lee, JS | 1 |
| Fujioka, N | 1 |
| Fritz, V | 1 |
| Upadhyaya, P | 1 |
| Kassie, F | 1 |
| Hecht, SS | 1 |
| Liu, L | 1 |
| Liu, R | 1 |
| Yu, W | 1 |
| Xu, F | 1 |
| Men, C | 1 |
| Wang, Q | 1 |
| Shen, Z | 1 |
| Zhou, Y | 1 |
| Levy, JI | 1 |
| Bode, AM | 1 |
| Dong, Z | 1 |
| Zhou, SF | 1 |
| Liu, JP | 1 |
| Chowbay, B | 1 |
| Bolotina, NA | 1 |
| Sharovskaia, IuIu | 1 |
| Kobliakov, VA | 1 |
| Benford, D | 1 |
| Dinovi, M | 1 |
| Setzer, RW | 1 |
| Szyfter, K | 1 |
| Kiwerska, K | 1 |
| Rydzanicz, M | 1 |
| Kruszyna, Ł | 1 |
| Zemleduch, T | 1 |
| Jagodziński, P | 1 |
| Urso, P | 1 |
| Wirsiy, YG | 1 |
| Cohen, MD | 1 |
| Adkins, B | 1 |
| Remacle, F | 1 |
| Kravchenko-Balasha, N | 2 |
| Levitzki, A | 2 |
| Levine, RD | 1 |
| Morselli, L | 1 |
| Passarini, F | 1 |
| Piccari, L | 1 |
| Vassura, I | 1 |
| Bernardi, E | 1 |
| ALLSOPP, CB | 1 |
| DICKENS, F | 1 |
| WEIL-MALHERBE, H | 1 |
| Delgado-Saborit, JM | 1 |
| Stark, C | 1 |
| Harrison, RM | 1 |
| Klarer, AC | 1 |
| McGregor, W | 1 |
| Song, Y | 1 |
| Mi, L | 1 |
| Li, Z | 1 |
| Shang, L | 1 |
| Hao, W | 1 |
| Paget, V | 1 |
| Lechevrel, M | 1 |
| André, V | 1 |
| Goff, JL | 1 |
| Pottier, D | 1 |
| Billet, S | 1 |
| Garçon, G | 1 |
| Shirali, P | 1 |
| Sichel, F | 1 |
| Zhang, K | 1 |
| Zhang, BZ | 1 |
| Li, SM | 1 |
| Wong, CS | 1 |
| Zeng, EY | 1 |
| Giri, SK | 1 |
| Yadav, A | 1 |
| Kumar, A | 1 |
| Dev, K | 1 |
| Gulati, S | 1 |
| Gupta, R | 1 |
| Aggarwal, N | 1 |
| Gautam, SK | 1 |
| Wang, XT | 1 |
| Miao, Y | 1 |
| Zhang, Y | 1 |
| Li, YC | 1 |
| Wu, MH | 1 |
| Yu, G | 1 |
| Obiri, S | 1 |
| Cobbina, SJ | 1 |
| Armah, FA | 1 |
| Luginaah, I | 1 |
| Rodriguez, JW | 1 |
| Kohan, MJ | 1 |
| King, LC | 1 |
| Kirlin, WG | 1 |
| KULCSAR, S | 1 |
| AGATE, FJ | 1 |
| ANTOPOL, W | 1 |
| GLAUBACH, S | 1 |
| AGATE, F | 1 |
| GRAFF, S | 1 |
| KOLOMAZNIK, L | 1 |
| ZDRAZIL, J | 2 |
| PICHA, F | 2 |
| GRANT, G | 1 |
| ROE, FJ | 2 |
| HERROLD, KM | 1 |
| ROVATI, L | 1 |
| RAGAGLIA, G | 1 |
| DELUCA, F | 1 |
| MILLER, JF | 1 |
| GRANT, GA | 1 |
| ARGUS, MF | 1 |
| ARCOS, JC | 1 |
| SULA, JP | 1 |
| ALFRED, LJ | 2 |
| GLOBERSON, A | 2 |
| BERWALD, Y | 1 |
| PREHN, RT | 1 |
| SKRAMOVSKY, V | 1 |
| JACQUIER, A | 1 |
| DAUDEL, P | 1 |
| BAUDYSOVA, M | 1 |
| HOLECKOVA, E | 1 |
| SEKLA, B | 1 |
| FELDMAN, M | 1 |
| MARTYNIUK, VA | 1 |
| KOCH, R | 1 |
| SCHENCK, GO | 1 |
| THIERY, M | 1 |
| VANGIJSEGEM, M | 1 |
| PYLEV, LN | 1 |
| RIGDON, RH | 1 |
| NEAL, J | 1 |
| MALLET, L | 1 |
| HEROS, M | 1 |
| Uno, S | 1 |
| Dalton, TP | 1 |
| Derkenne, S | 1 |
| Curran, CP | 1 |
| Miller, ML | 1 |
| Shertzer, HG | 1 |
| Nebert, DW | 2 |
| Xu, Z | 1 |
| Jin, Y | 1 |
| Martin, KR | 1 |
| Jokinen, MP | 1 |
| Honeycutt, HP | 1 |
| Quinn, A | 1 |
| Kari, FW | 1 |
| Barrett, JC | 1 |
| French, JE | 1 |
| Fitzgerald, DJ | 1 |
| Robinson, NI | 1 |
| Pester, BA | 1 |
| Shor, LM | 1 |
| Kosson, DS | 1 |
| Rockne, KJ | 1 |
| Young, LY | 1 |
| Taghon, GL | 1 |
| Luch, A | 1 |
| Mooney, LA | 1 |
| Madsen, AM | 1 |
| Tang, D | 2 |
| Orjuela, MA | 1 |
| Tsai, WY | 1 |
| Garduno, ER | 1 |
| Perera, FP | 3 |
| Rowe, CA | 1 |
| Nantz, MP | 1 |
| Deniera, C | 1 |
| Green, K | 1 |
| Talcott, ST | 1 |
| Percival, SS | 1 |
| Perera, F | 1 |
| Whyatt, R | 1 |
| Lederman, SA | 1 |
| Jedrychowski, W | 1 |
| Inomata, K | 1 |
| Oga, A | 1 |
| Kawauchi, S | 1 |
| Furuya, T | 1 |
| Sasaki, K | 1 |
| Calaf, GM | 1 |
| Alvarado, ME | 1 |
| Hei, TK | 1 |
| Jones-Otazo, HA | 1 |
| Diamond, ML | 1 |
| Richardson, GM | 1 |
| Liao, CM | 2 |
| Chiang, KC | 1 |
| Chen, SC | 1 |
| Balansky, R | 2 |
| D'Agostini, F | 3 |
| Ganchev, G | 2 |
| Izzotti, A | 2 |
| Di Marco, B | 1 |
| Lubet, RA | 1 |
| Zanesi, N | 1 |
| Croce, CM | 1 |
| De Flora, S | 3 |
| Lee, YJ | 1 |
| Kao, ES | 1 |
| Chu, CY | 1 |
| Lin, WL | 1 |
| Chiou, YH | 1 |
| Tseng, TH | 1 |
| Ma, Q | 1 |
| Lu, AY | 1 |
| Iltcheva, M | 1 |
| Steele, VE | 1 |
| Mizrachy-Schwartz, S | 1 |
| Ben-Bassat, H | 1 |
| Klein, S | 1 |
| Lee, BM | 2 |
| Shim, GA | 1 |
| Lavoué, J | 1 |
| Gérin, M | 1 |
| Côté, J | 1 |
| Lapointe, R | 1 |
| Sevigny, M | 1 |
| Cogliano, VJ | 1 |
| Baan, RA | 1 |
| Straif, K | 1 |
| Grosse, Y | 1 |
| Secretan, B | 1 |
| El Ghissassi, F | 1 |
| Aries, E | 1 |
| Anderson, DR | 1 |
| Fisher, R | 1 |
| Aust, AE | 1 |
| Antczak, MR | 1 |
| Maher, VM | 1 |
| McCormick, JJ | 1 |
| Sparnins, VL | 1 |
| Venegas, PL | 1 |
| Wattenberg, LW | 1 |
| Estabrook, RW | 1 |
| Saeki, Y | 1 |
| Chacos, N | 1 |
| Capdevila, J | 1 |
| Prough, RA | 1 |
| Honn, KV | 1 |
| Bockman, RS | 1 |
| Marnett, LJ | 1 |
| Weinstein, IB | 2 |
| Pelkonen, O | 1 |
| Lindstedt, G | 1 |
| Sollenberg, J | 1 |
| Teichmann, B | 1 |
| Grimmer, G | 1 |
| Brune, H | 1 |
| Deutsch-Wenzel, R | 1 |
| Dettbarn, G | 1 |
| Misfeld, J | 1 |
| Abel, U | 1 |
| Timm, J | 1 |
| Rämet, M | 1 |
| Castrén, K | 1 |
| Järvinen, K | 1 |
| Pekkala, K | 1 |
| Turpeenniemi-Hujanen, T | 1 |
| Soini, Y | 1 |
| Pääkkö, P | 1 |
| Vähäkangas, K | 1 |
| Cox, LA | 1 |
| Soni, MG | 1 |
| Krishna, TP | 1 |
| Krishnaswamy, K | 2 |
| Han, CZ | 1 |
| Guo, Y | 1 |
| Jing, JX | 2 |
| Nokso-Koivisto, P | 1 |
| Pukkala, E | 1 |
| Pangrekar, J | 1 |
| Jagadeesan, V | 1 |
| Rossi, GA | 1 |
| Balansky, RM | 1 |
| Butler, JP | 1 |
| Post, GB | 1 |
| Lioy, PJ | 2 |
| Waldman, JM | 1 |
| Greenberg, A | 1 |
| Attias, L | 1 |
| Bucchi, AR | 1 |
| Maranghi, F | 1 |
| Holt, S | 1 |
| Marcello, I | 1 |
| Zapponi, GA | 1 |
| Gustavsson, P | 1 |
| Bellander, T | 1 |
| Johansson, L | 1 |
| Salmonsson, S | 1 |
| Szymczak, W | 1 |
| Tolbert, PE | 1 |
| Pfeifer, GP | 1 |
| Denissenko, MF | 1 |
| Han, C | 1 |
| Sun, GX | 1 |
| Hussain, SP | 1 |
| Harris, CC | 1 |
| Hengstler, JG | 1 |
| Van der Burg, B | 1 |
| Steinberg, P | 1 |
| Oesch, F | 1 |
| Garcia-Closas, M | 1 |
| Rothman, N | 1 |
| Lubin, J | 1 |
| Khalili, H | 1 |
| Zhang, FJ | 1 |
| Harvey, RG | 1 |
| Dipple, A | 1 |
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| Dikun, PP | 1 |
| Tyndyk, ML | 1 |
| Savochkina, IV | 1 |
| Yermilov, VB | 1 |
| Zabezhinski, MA | 1 |
| Adlkofer, F | 1 |
| Hoffmann, D | 1 |
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| Puisieux, A | 1 |
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| Coffing, SL | 1 |
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| Morioka, T | 1 |
| Fremlin, JH | 1 |
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| Reed, E | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized, Double-Blinded, Placebo-Controlled Study With Immunotype Specific Dietary Supplements to Improve Inflammatory Age® by Edifice Health[NCT04983017] | 750 participants (Anticipated) | Interventional | 2021-08-10 | Recruiting | |||
| Determining Levels of [D10] Phenanthrene Tetraol in Smokers' Urine[NCT01092650] | Phase 1 | 30 participants (Anticipated) | Interventional | 2007-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
34 reviews available for benzo(a)pyrene and Neoplasms
| Article | Year |
|---|---|
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; | 2015 |
Can Exposure to Environmental Pollutants Be Associated with Less Effective Chemotherapy in Cancer Patients?
Topics: Benzo(a)pyrene; Environmental Exposure; Environmental Pollutants; Humans; Neoplasms; Particulate Mat | 2022 |
Inflammation and the chemical carcinogen benzo[a]pyrene: Partners in crime.
Topics: Animals; Benzo(a)pyrene; Carcinogens; Humans; Inflammation; Neoplasms | 2017 |
Filling the gap between chemical carcinogenesis and the hallmarks of cancer: A temporal perspective.
Topics: Benzo(a)pyrene; Carcinogenesis; Carcinogens; Cell Death; Cell Proliferation; Cell Survival; Humans; | 2018 |
Carcinogens and DNA damage.
Topics: Amines; Animals; Aristolochic Acids; Benzo(a)pyrene; Carcinogens; Cross-Linking Reagents; Diet; DNA; | 2018 |
Disturbances in H
Topics: Animals; Benzo(a)pyrene; Carcinogenesis; Carcinogens; Environmental Exposure; Humans; Liver; Neoplas | 2019 |
Integrating toxicogenomics into human health risk assessment: lessons learned from the benzo[a]pyrene case study.
Topics: Animals; Benzo(a)pyrene; Carcinogens; Dose-Response Relationship, Drug; Humans; Neoplasms; Risk Asse | 2015 |
Significance of adverse outcome pathways in biomarker-based environmental risk assessment in aquatic organisms.
Topics: Animals; Aquatic Organisms; Benzo(a)pyrene; Biomarkers; Environmental Exposure; Environmental Monito | 2015 |
Research on cruciferous vegetables, indole-3-carbinol, and cancer prevention: A tribute to Lee W. Wattenberg.
Topics: Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Biomarkers; Brassicaceae; Carcinogens; Cell Line, | 2016 |
Epigallocatechin 3-gallate and green tea catechins: United they work, divided they fail.
Topics: Adenoma; Aerosols; Animals; Anticarcinogenic Agents; Antioxidants; Benzo(a)pyrene; Biological Availa | 2009 |
Polymorphism of human cytochrome P450 enzymes and its clinical impact.
Topics: Alleles; Animals; Benzo(a)pyrene; Chromosome Mapping; Cytochrome P-450 Enzyme System; Enzyme Inducti | 2009 |
Application of the margin-of-exposure (MoE) approach to substances in food that are genotoxic and carcinogenic e.g.: benzo[a]pyrene and polycyclic aromatic hydrocarbons.
Topics: Animals; Benzo(a)pyrene; Carcinogens; Data Interpretation, Statistical; Diet; Dose-Response Relation | 2010 |
Replication of damaged genomes.
Topics: Animals; Benzo(a)pyrene; Cloning, Molecular; DNA; DNA Damage; DNA Repair; DNA Replication; DNA-Direc | 2011 |
THE CARCINOGEN 3,4-BENZPYRENE IN THE LIVING ENVIRONMENT AND HUMAN ORGANISM.
Topics: Air Pollution; Anthracosilicosis; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Food Preservation; Lung | 1963 |
[Environmental carcinogens and p53 gene mutation].
Topics: Aflatoxin B1; Animals; Benzo(a)pyrene; Carcinogens, Environmental; Genes, p53; Humans; Mutation; Neo | 2004 |
Nature and nurture - lessons from chemical carcinogenesis.
Topics: Animals; Benzo(a)pyrene; Carcinogens; DNA; DNA Adducts; DNA, Complementary; Environment; Humans; Hyd | 2005 |
CYP1A induction and human risk assessment: an evolving tale of in vitro and in vivo studies.
Topics: Amines; Animals; Anti-Ulcer Agents; Benzo(a)pyrene; Biotransformation; Carcinogens; Cell Transformat | 2007 |
Use of mechanistic data in IARC evaluations.
Topics: Animals; Benzo(a)pyrene; Carcinogens; Humans; International Agencies; Marine Toxins; Microcystins; N | 2008 |
Prostaglandins and cancer: a review of tumor initiation through tumor metastasis.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Differentiation; Cell Division; Cell Transf | 1981 |
Metabolism of polycyclic aromatic hydrocarbons: etiologic role in carcinogenesis.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Carcinogens; Cytochrome P-450 Enzyme Syste | 1982 |
Polycyclic aromatic hydrocarbons in the occupational environment: with special reference to benzo[a]pyrene measurements in Swedish industry.
Topics: Air Pollutants; Air Pollutants, Occupational; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Fossil Fuel | 1982 |
Oils and cancer.
Topics: 2-Naphthylamine; Benzo(a)pyrene; Carcinogens; Chlorine Compounds; Esophageal Neoplasms; Ethanolamine | 1997 |
Formation and repair of DNA lesions in the p53 gene: relation to cancer mutations?
Topics: 5-Methylcytosine; Animals; Benzo(a)pyrene; Breast Neoplasms; Carcinogens, Environmental; Colonic Neo | 1998 |
p53 mutation spectrum and load: the generation of hypotheses linking the exposure of endogenous or exogenous carcinogens to human cancer.
Topics: Aflatoxin B1; Benzo(a)pyrene; Carcinogens; Carcinogens, Environmental; Codon; Genes, p53; Humans; Mo | 1999 |
Interspecies differences in cancer susceptibility and toxicity.
Topics: Aflatoxin B1; Animals; Antineoplastic Agents, Hormonal; Benzo(a)pyrene; Cardiotonic Agents; Cricetin | 1999 |
Protection by dietary compounds against mutation in a transgenic rodent.
Topics: Aflatoxin B1; Animals; Animals, Genetically Modified; Bacterial Proteins; Benzo(a)pyrene; Carcinogen | 2001 |
Synergistic mechanisms in carcinogenesis by polycyclic aromatic hydrocarbons and by tobacco smoke: a bio-historical perspective with updates.
Topics: Animals; Benzo(a)pyrene; Carcinogens; Cell Transformation, Neoplastic; DNA; DNA Damage; Drug Synergi | 2001 |
Epidemiologic evidence of cancer in aluminum reduction plant workers.
Topics: Aluminum; Benzo(a)pyrene; Canada; Cross-Cultural Comparison; Cross-Sectional Studies; Humans; Incide | 1992 |
Relevance of quantitation of benzo(a)pyrene metabolites in animal excretes to evaluate individual human cancer risk.
Topics: Animals; Benzo(a)pyrene; Carcinogenicity Tests; Humans; Male; Metabolic Clearance Rate; Neoplasms; N | 1992 |
Use of human epidermal cells in the study of carcinogenesis.
Topics: Benzo(a)pyrene; Carcinogens; Cell Differentiation; Cells, Cultured; DNA; Epidermal Cells; ErbB Recep | 1989 |
Epidemiological and experimental applications to occupational cancer prevention.
Topics: Animals; Benzo(a)pyrene; Carcinogenicity Tests; Carcinogens; Cohort Studies; DNA; DNA Adducts; Envir | 1989 |
Determination of carcinogen-DNA adducts by immunoassay.
Topics: Antibodies, Monoclonal; Antigens; Benzo(a)pyrene; Blood Cells; Carcinogens; Cell Nucleus; Cisplatin; | 1989 |
Genetic targets in multistage carcinogenesis.
Topics: Animals; Benzo(a)pyrene; Cell Transformation, Neoplastic; DNA; DNA Replication; Genes, Viral; Mice; | 1985 |
[Problems of the maximum permissible exposure level of benzo(a)pyrene in the air of the work area (a review of the literature)].
Topics: Air Pollutants, Occupational; Benzo(a)pyrene; Chemical Industry; Dose-Response Relationship, Drug; H | 1988 |
1 trial available for benzo(a)pyrene and Neoplasms
| Article | Year |
|---|---|
Antioxidant vitamin supplementation reduces benzo(a)pyrene-DNA adducts and potential cancer risk in female smokers.
Topics: Adult; Antioxidants; Ascorbic Acid; Benzo(a)pyrene; Chromatography, High Pressure Liquid; Cotinine; | 2005 |
118 other studies available for benzo(a)pyrene and Neoplasms
| Article | Year |
|---|---|
Profiling of seasonal variation in and cancer risk assessment of benzo(a)pyrene and heavy metals in drinking water from Kirkuk city, Iraq.
Topics: Adult; Benzo(a)pyrene; Child; Drinking Water; Environmental Monitoring; Humans; Iraq; Metals, Heavy; | 2022 |
The effect of benzo[alpha]pyrene on DNA methylation and telomerase activity in human normal and cancer cells.
Topics: Benzo(a)pyrene; Cell Line; Cell Proliferation; DNA Methylation; Environmental Pollutants; Gene Expre | 2022 |
Risk characterization of human exposure to polycyclic aromatic hydrocarbons in vulnerable groups.
Topics: Benzo(a)pyrene; Carcinogenesis; Carcinogens; Child; Environmental Monitoring; Environmental Pollutan | 2023 |
In vitro gastrointestinal mobilization and oral bioaccessibility of PAHs in contrasting soils and associated cancer risks: Focus on PAH nonextractable residues.
Topics: Benzo(a)pyrene; Eating; Gastrointestinal Tract; Humans; Neoplasms; Polycyclic Aromatic Hydrocarbons; | 2019 |
Carcinogenic risk from exposure to PM
Topics: Air Pollutants; Air Pollution, Indoor; Benzo(a)pyrene; Carcinogens; Coal; Cooking; Environmental Exp | 2020 |
Comparative risk estimates of an expanded list of PAHs from community and source-influenced air sampling.
Topics: Air Pollutants; Benzo(a)pyrene; Carcinogens; Environmental Monitoring; Fluorenes; Humans; Minnesota; | 2020 |
Benzo(a)pyrene affects proliferation with reference to metabolic genes and ROS/HIF-1α/HO-1 signaling in A549 and MCF-7 cancer cells.
Topics: Benzo(a)pyrene; Cell Proliferation; Humans; MCF-7 Cells; Neoplasms; Reactive Oxygen Species; Signal | 2022 |
MicroRNA expression profiling and the role of ALCAM modulating tumor growth and metastasis in benzo[a]pyrene-transformed 16HBE cells.
Topics: Animals; Antigens, CD; Benzo(a)pyrene; Carcinogens; Cell Adhesion Molecules, Neuronal; Cell Line, Tu | 2020 |
Search for Internal Cancers in Mice Tattooed with Inks of High Contents of Potential Carcinogens: A One-Year Autopsy Study of Red and Black Tattoo Inks Banned in the Market.
Topics: Aniline Compounds; Animals; Benzo(a)pyrene; Carcinogens; Cocarcinogenesis; Ink; Mice; Neoplasms; Tat | 2017 |
Clusterin and neuropilin-2 as potential biomarkers of tumor progression in benzo[a]pyrene-transformed 16HBE cells xenografted nude mouse model.
Topics: Animals; Area Under Curve; Benzo(a)pyrene; Biomarkers, Tumor; Carcinogens; Cell Line; Cell Transform | 2017 |
Human health risk assessment and PAHs in a stretch of river Ganges near Kanpur.
Topics: Adolescent; Adult; Benzo(a)pyrene; Carcinogens; Child; Environmental Exposure; Environmental Monitor | 2017 |
Assessment of Polycyclic Aromatic Hydrocarbons in School Playground Soils in Urban Gwangju, South Korea.
Topics: Benzo(a)pyrene; Cities; Environmental Exposure; Environmental Monitoring; Humans; Neoplasms; Polycyc | 2018 |
Probabilistic approach for assessing cancer risk due to benzo[a]pyrene in barbecued meat: Informing advice for population groups.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Benzo(a)pyrene; Body Weight; Carcinogens; Child; Child, | 2018 |
Mortality and cancer incidence in aluminum smelter workers: a 5-year update.
Topics: Aluminum; Benzo(a)pyrene; Female; Humans; Incidence; Male; Metallurgy; Middle Aged; Neoplasms; Occup | 2014 |
Polycyclic aromatic hydrocarbons associated with total suspended particles and surface soils in Kunming, China: distribution, possible sources, and cancer risks.
Topics: Air Pollutants; Benzo(a)pyrene; Carcinogens; China; Chrysenes; Cities; Coal; Fluorenes; Fluorine; Hu | 2015 |
Exome-wide mutation profile in benzo[a]pyrene-derived post-stasis and immortal human mammary epithelial cells.
Topics: Benzo(a)pyrene; Carcinogens, Environmental; Cells, Cultured; Chromosome Aberrations; Epithelial Cell | 2014 |
Detection of benzo[a]pyrene-guanine adducts in single-stranded DNA using the α-hemolysin nanopore.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Alkylating Agents; Benzo(a)pyrene; DNA Adducts; | 2015 |
Risk assessment and uncertainty analysis of PAHs in the sediments of the Yangtze River Estuary, China.
Topics: Benzo(a)pyrene; China; Environmental Monitoring; Estuaries; Geography; Geologic Sediments; Humans; M | 2016 |
Between-airport heterogeneity in air toxics emissions associated with individual cancer risk thresholds and population risks.
Topics: Air Pollutants; Air Pollution; Benzene; Benzo(a)pyrene; Butadienes; Environmental Exposure; Humans; | 2009 |
[Ah receptor-independent inhibition of gap junction intercellular communications in hepatoma cell culture 27 by polycyclic aromatic hydrocarbons].
Topics: Animals; Benzo(a)pyrene; Carcinogens; Cell Line, Tumor; Cytochrome P-450 Enzyme System; Down-Regulat | 2009 |
[Mutations of tumor suppressor gemne TP53 in tobacco smoke-associated tumors].
Topics: Benzo(a)pyrene; Carcinogens; Cell Cycle; Cell Proliferation; Genes, p53; Humans; Neoplasms; Point Mu | 2009 |
Changes in biologic and/or immunologic parameters induced by intratracheal instillation of pregnant mice with benzo(a)pyrene are potentially confounded by anesthesia.
Topics: Anesthesia; Animals; Animals, Newborn; Benzo(a)pyrene; Cells, Cultured; Female; Intubation, Intratra | 2010 |
Information-theoretic analysis of phenotype changes in early stages of carcinogenesis.
Topics: Animals; Benzo(a)pyrene; Cell Line, Transformed; Cell Transformation, Neoplastic; Cell Transformatio | 2010 |
Risk assessment applied to air emissions from a medium-sized Italian MSW incinerator.
Topics: Adult; Air Pollutants; Benzo(a)pyrene; Child; Dose-Response Relationship, Drug; Humans; Incineration | 2011 |
Effects of ultraviolet radiation on 3,4-benzpyrene and other polycyclic aromatic hydrocarbons; carcinogenic activity of aqueous extracts from irradiated 3,4-benzpyrene.
Topics: Benzo(a)pyrene; Benzopyrenes; Carcinogens; Humans; Neoplasms; Polycyclic Aromatic Hydrocarbons; Ultr | 1946 |
Factors affecting carcinogenesis; the effect of hydrogenation of lipid solvents on carcinogenesis by 3,4-benzpyrene.
Topics: Benzo(a)pyrene; Benzopyrenes; Carcinogenesis; Humans; Hydrogenation; Lipids; Neoplasms; Solvents | 1946 |
Carcinogenic potential, levels and sources of polycyclic aromatic hydrocarbon mixtures in indoor and outdoor environments and their implications for air quality standards.
Topics: Air Pollutants; Air Pollution, Indoor; Benzo(a)pyrene; Carcinogens, Environmental; Environmental Exp | 2011 |
Polycyclic aromatic hydrocarbons: 15 Listings - benz[a]anthracene, benzo[b]fluoranthene, benzo[j]fluoranthene, benzo[k]fluoranthene, benzo[a]pyrene, dibenz[a,h]acridine, dibenz[a,j]acridine, dibenz[a,h]anthracene, 7H-dibenzo[c,g]carbazole, dibenzo[a,e]pyr
Topics: Acridines; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Carbazoles; Carcinogens, Envir | 2011 |
In vitro malignant transformation of human bronchial epithelial cells induced by benzo(a)pyrene.
Topics: Animals; Benzo(a)pyrene; Bronchi; Carcinogens; Cell Line; Cell Movement; Cell Transformation, Neopla | 2012 |
Benzo[a]pyrene, aflatoxine B₁ and acetaldehyde mutational patterns in TP53 gene using a functional assay: relevance to human cancer aetiology.
Topics: Acetaldehyde; Aflatoxin B1; Benzo(a)pyrene; Carcinogens; Fibroblasts; Humans; Mutagens; Mutation; Ne | 2012 |
Calculated respiratory exposure to indoor size-fractioned polycyclic aromatic hydrocarbons in an urban environment.
Topics: Air Pollutants; Air Pollution, Indoor; Benzo(a)pyrene; China; Environmental Exposure; Humans; Neopla | 2012 |
CYP1A1 gene polymorphisms: modulator of genetic damage in coal-tar workers.
Topics: Adult; Benzo(a)pyrene; Chemical Industry; Coal Tar; Cytochrome P-450 CYP1A1; DNA Damage; Epithelial | 2012 |
Polycyclic aromatic hydrocarbons (PAHs) in urban soils of the megacity Shanghai: occurrence, source apportionment and potential human health risk.
Topics: Benzo(a)pyrene; Carcinogens; China; Cities; Coal; Environmental Monitoring; Groundwater; Humans; Mod | 2013 |
Assessment of cancer and noncancer health risks from exposure to PAHs in street dust in the Tamale Metropolis, Ghana.
Topics: Administration, Inhalation; Adult; Air Pollutants; Anthracenes; Benzo(a)pyrene; Child; Chrysenes; Ci | 2013 |
Detection of DNA adducts in developing CD4+ CD8+ thymocytes and splenocytes following in utero exposure to benzo[a]pyrene.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; Carcinogens, Environmen | 2002 |
[Experimental testicular neoplasms induced by 3,4-benzpyrene].
Topics: Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Humans; Male; Neoplasms; Neoplasms, Exper | 1953 |
The nonessentiality of the hypophysis for the induction of tumors with 3,4-benzpyrene.
Topics: Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Neoplasms; Pituitary Gland; Polycyclic Compounds | 1955 |
[Incidence of benign, precancerous and cancerous tumors in the respiratory tract of foundry workers employed in areas containing large amounts of atmospheric 3,4-benzpyrenes].
Topics: Benzo(a)pyrene; Benzopyrenes; Humans; Incidence; Neoplasms; Occupational Diseases; Respiratory Syste | 1963 |
THE EFFECT OF PHENANTHRENE ON TUMOUR INDUCTION BY 3,4-BENZOPYRENE ADMINISTERED TO NEWLY BORN MICE.
Topics: Animals; Animals, Newborn; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Carcinoma, Hepatocellular; Liv | 1963 |
THE EFFECTS OF BENZO(A)PYRENE, CIGARETTE SMOKE CONDENSATE AND ATMOSPHERIC POLLUTANTS ON THE RESPIRATORY SYSTEM OF SYRIAN HAMSTERS.
Topics: Air Pollution; Animals; Benzo(a)pyrene; Benzopyrenes; Bronchial Neoplasms; Carcinogens; Carcinoma; C | 1963 |
[EXPERIMENTAL RESEARCH ON CARCINOGENESIS IN THE GALLBLADDER INDUCED WITH 3,4-BENZOPYRENE].
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogenesis; Gallbladder Neoplasms; Neoplasms; Neoplasms, | 1963 |
EFFECT OF THYMECTOMY ON THE INDUCTION OF SKIN TUMOURS BY 3,4-BENZOPYRENE.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Mice; Neoplasm Regression, Spontaneous; Neoplasm | 1963 |
FAILURE OF MONO-CHLOROACETONE TO INFLUENCE 3,4-BENZPYRENE MOUSE SKIN TUMORIGENESIS.
Topics: Acetone; Animals; Antineoplastic Agents; Benzo(a)pyrene; Benzopyrenes; Cell Transformation, Neoplast | 1963 |
DIFFERENTIAL TOXICITY RESPONSE OF NORMAL AND NEOPLASTIC CELLS IN VITRO TO 3,4-BENZOPYRENE AND 3-METHYLCHOLANTHRENE.
Topics: Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cricetinae; Embryo, Mammalian; Embryo, Nonmammalian; Fetu | 1964 |
[DETERMINATION OF 3,4-BENZPYRENE IN THE PRAGUE ATMOSPHERE].
Topics: Air Pollution; Atmosphere; Benzo(a)pyrene; Benzopyrenes; Chromatography; Czechoslovakia; Lung Neopla | 1963 |
[ON THE INTERACTION IN VIVO OF 3,4-BENZOPYRENE AND MOUSE SKIN DESOXYRIBONUCLEIC ACID].
Topics: Benzo(a)pyrene; Benzopyrenes; DNA; Mice; Neoplasms; Research; Skin Neoplasms; Toxicology | 1964 |
THE RESISTANCE OF TWO LINES OF RATS TO TUMOUR INDUCTION BY 3,4-BENZPYRENE.
Topics: Animals; Antigens; Benzo(a)pyrene; Benzopyrenes; Carcinoma; Carcinoma 256, Walker; Mortality; Neopla | 1964 |
[PRESENCE OF 3,4-BENZOPYRENE IN GLASSWORKS AND FOUNDRIES].
Topics: Air Pollution; Benzo(a)pyrene; Benzopyrenes; Czechoslovakia; Humans; Neoplasms; Occupational Disease | 1964 |
ANTIGENIC SPECIFICITY OF BENZO(A)PYRENE-INDUCED SARCOMAS.
Topics: Animals; Antigens; Benzo(a)pyrene; Benzopyrenes; Epitopes; Mice; Neoplasms; Radiation Effects; Resea | 1964 |
INTERACTION OF SOLUBLE COMPLEXES OF TRITIATED 3,4-BENZOPYRENE AND ANIMAL CELLS IN VITRO.
Topics: Benzo(a)pyrene; Benzopyrenes; Caffeine; In Vitro Techniques; Metabolism; Mice; Neoplasms; Research; | 1964 |
[REACTIVE CHANGES IN THE LINGUAL EPITHELIUM OF WHITE MICE INDUCED BY 3,4-BENZOPYRENE].
Topics: Benzo(a)pyrene; Benzopyrenes; Epithelium; Mice; Neoplasms; Neoplasms, Experimental; Pathology; Pharm | 1964 |
[POSSIBILITIES OF THE EFFECT OF SENSITIZED AND DESENSITIZED SUPPLEMENTS IN RADIOCHEMISTRY AND RADIOBIOLOGY. VI. THE EFFECT OF IRRADIATION ON TUMOR FORMATION AFTER 3,4-BENZOPYRENE].
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Gold Colloid; Gold Colloid, Radioactive; Gold Isotopes; Mice; | 1965 |
SPECIES AND STRAIN DIFFERENCES IN THE SUSCEPTIBILITY OF THE CERVICO-VAGINAL SQUAMOUS EPITHELIUM TO 3,4-BENZO(A)PYRENE.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinoma; Carcinoma, Squamous Cell; Cricetinae; Female; Gene | 1965 |
[ON EXPERIMENTAL PRODUCTION OF PULMONARY CANCER WITH THE USE OF 3,4-BENZOPYRENE IN RATS].
Topics: Benzo(a)pyrene; Benzopyrenes; Lung Neoplasms; Neoplasms; Neoplasms, Experimental; Research | 1964 |
EFFECT OF INTRATRACHEAL INJECTION OF BENZO (A) PYRENE ON DUCKS.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carbon; Carcinogens; Cysts; Ducks; Lung Neoplasms; Metaplasia | 1965 |
[Research on the fixation of polybenzene hydrocarbons of the 3,4-benzopyrene type by microorganisms and their roles as vectors of cancer-ogenic substances].
Topics: Benzo(a)pyrene; Benzopyrenes; Genetic Vectors; Hydrocarbons; Mycobacterium tuberculosis; Neoplasms; | 1961 |
Oral exposure to benzo[a]pyrene in the mouse: detoxication by inducible cytochrome P450 is more important than metabolic activation.
Topics: Administration, Oral; Alanine Transaminase; Animals; Aspartate Aminotransferases; Benzo(a)pyrene; Bi | 2004 |
Tumor profile of novel p53 heterozygous Tg.AC (v-Ha-ras) bitransgenic mice treated with benzo(a)pyrene and fed dietary N-acetyl-L-cysteine (NAC).
Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Antioxidants; Benzo(a)pyrene; Carcinogens; Diet; F | 2004 |
Application of benzo(a)pyrene and coal tar tumor dose-response data to a modified benchmark dose method of guideline development.
Topics: Animals; Benchmarking; Benzo(a)pyrene; Carcinogens, Environmental; Coal Tar; Dose-Response Relations | 2004 |
Combined effects of contaminant desorption and toxicity on risk from PAH contaminated sediments.
Topics: Benzo(a)pyrene; Biological Availability; Carcinogens, Environmental; Geologic Sediments; Humans; Mod | 2004 |
Inhibition of neoplastic transformation of benzo[alpha]pyrene-treated BALB/c 3T3 murine cells by a phytochemical extract of passionfruit juice.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Apoptosis; Benzo(a)pyrene; Caspase 3; Caspases; Cell Divi | 2004 |
DNA damage from polycyclic aromatic hydrocarbons measured by benzo[a]pyrene-DNA adducts in mothers and newborns from Northern Manhattan, the World Trade Center Area, Poland, and China.
Topics: Adult; Benzo(a)pyrene; Biomarkers; Carcinogens; China; Cohort Studies; DNA Adducts; DNA Damage; Envi | 2005 |
Global genomic changes induced by two-stage carcinogen exposure are precancerous alterations in non-transformed human liver epithelial THLE-3 cells.
Topics: Benzo(a)pyrene; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Chromosomes, Human, Pair 11 | 2005 |
Oncoprotein expression and morphological phenotypes of human breast epithelial cells transformed by the c-Ha-ras oncogene.
Topics: Benzo(a)pyrene; Breast Neoplasms; Carcinogens; Cell Differentiation; Cell Line, Transformed; Cell Li | 2005 |
An interagency comparison of screening-level risk assessment approaches.
Topics: Benzo(a)pyrene; Environmental Exposure; Environmental Pollutants; Humans; International Agencies; Mo | 2005 |
Probabilistic risk assessment for personal exposure to carcinogenic polycyclic aromatic hydrocarbons in Taiwanese temples.
Topics: Adolescent; Adult; Air Pollutants; Benzo(a)pyrene; Carcinogens, Environmental; Child; Humans; Inhala | 2006 |
Health risk assessment on human exposed to environmental polycyclic aromatic hydrocarbons pollution sources.
Topics: Adolescent; Adult; Age Factors; Aged; Benzo(a)pyrene; California; Child; Child, Preschool; Dose-Resp | 2006 |
Influence of FHIT on benzo[a]pyrene-induced tumors and alopecia in mice: chemoprevention by budesonide and N-acetylcysteine.
Topics: Acetylcysteine; Acid Anhydride Hydrolases; Alopecia Areata; Animals; Anti-Inflammatory Agents; Benzo | 2006 |
Inhibitory effect of ailanthoidol on 12-O-tetradecanoyl-phorbol-13-acetate-induced tumor promotion in mouse skin.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Benzo(a)pyrene; Benzofurans; Carcinogens; | 2006 |
Potent carcinogenicity of cigarette smoke in mice exposed early in life.
Topics: Animals; Animals, Newborn; Benzo(a)pyrene; Body Weight; Carcinogens; Environmental Exposure; Female; | 2007 |
Optimization of energy-consuming pathways towards rapid growth in HPV-transformed cells.
Topics: Adenylate Kinase; Benzo(a)pyrene; Carcinogens; Cell Division; Cell Size; CSK Tyrosine-Protein Kinase | 2007 |
Dietary exposure estimation of benzo[a]pyrene and cancer risk assessment.
Topics: Benzo(a)pyrene; Chromatography, High Pressure Liquid; Cooking; Food Analysis; Food Contamination; Hu | 2007 |
Mortality and cancer experience of Quebec aluminum reduction plant workers. Part I: The reduction plants and coal tar pitch volatile (CTPV) exposure assessment.
Topics: Air Pollutants, Occupational; Aluminum; Benzene; Benzo(a)pyrene; Coal Tar; Cohort Studies; Humans; M | 2007 |
Mortality and cancer experience of Quebec aluminum reduction plant workers, part 4: cancer incidence.
Topics: Aluminum; Benzo(a)pyrene; Cohort Studies; Female; Humans; Incidence; Male; Metallurgy; Neoplasms; Oc | 2007 |
Exposure assessment of workers to airborne PCDD/Fs, PCBs and PAHs at an electric arc furnace steelmaking plant in the UK.
Topics: Air Pollutants, Occupational; Benzo(a)pyrene; Dioxins; England; Environmental Monitoring; Humans; In | 2008 |
Identifying human cells capable of metabolizing various classes of carcinogens.
Topics: Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Line; Cells, Cultured; DNA Replication; Epithelium; | 1981 |
Glutathione S-transferase activity: enhancement by compounds inhibiting chemical carcinogenesis and by dietary constituents.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Diet; Female; Glutathione Transferase; Intestina | 1982 |
Polycyclic hydrocarbon metabolism: a plethora of phenomena.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Cytochrome P-450 Enzyme System; Intracellular Membranes; Lung | 1980 |
Molecular epidemiology and carcinogen-DNA adduct detection: new approaches to studies of human cancer causation.
Topics: Benzo(a)pyrene; Benzopyrenes; Body Fluids; Carcinogens; Disease Susceptibility; DNA; Humans; Immunoa | 1982 |
[Significance of chemical carcinogens in the atmosphere for carcinogenesis].
Topics: Air Pollution; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens, Environmental; Environmental Expo | 1983 |
The contribution of polycyclic aromatic hydrocarbons to the carcinogenic impact of emission condensate from coal-fired residential furnaces evaluated by topical application to the skin of mice.
Topics: Administration, Topical; Air Pollutants; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinoma, Squamous | 1984 |
Coke production.
Topics: Air Pollutants, Occupational; Animals; Benzo(a)pyrene; Carcinogens; Coal; Coke; Humans; Industry; Mi | 1984 |
p53 protein expression is correlated with benzo[a]pyrene-DNA adducts in carcinoma cell lines.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adenocarcinoma; Benzo(a)pyrene; Biotransformatio | 1995 |
An exact analysis of the multistage model explaining dose-response concavity.
Topics: Algorithms; Benzo(a)pyrene; Butadienes; Carcinogens; Cell Transformation, Neoplastic; Chloroform; Do | 1995 |
Human leukocyte glutathione S-transferase isozyme (class mu) and susceptibility to smoking-related cancers.
Topics: Adult; Animals; Benzo(a)pyrene; Biomarkers; Disease Susceptibility; Female; Glutathione Transferase; | 1995 |
[A study on the relationship between malignant tumour mortality and environmental pollution in Beicun countryside of Datong City].
Topics: Benzo(a)pyrene; China; Copper; Digestive System Neoplasms; Environmental Pollution; Food Contaminati | 1995 |
Past exposure to asbestos and combustion products and incidence of cancer among Finnish locomotive drivers.
Topics: Asbestos; Benzo(a)pyrene; Coal; Cohort Studies; Creosote; Dust; Finland; Humans; Incidence; Industry | 1994 |
Effects of riboflavin deficiency and riboflavin administration on carcinogen-DNA binding.
Topics: Animals; Benzo(a)pyrene; Biomarkers; Carcinogenicity Tests; DNA; Male; Neoplasms; Protein Binding; R | 1993 |
Pulmonary alveolar macrophages in molecular epidemiology and chemoprevention of cancer.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Acetylcysteine; Adolescent; Adult; Aged; Animals | 1993 |
Assessment of carcinogenic risk from personal exposure to benzo(a)pyrene in the Total Human Environmental Exposure Study (THEES).
Topics: Air Pollutants; Benzo(a)pyrene; Environmental Exposure; Female; Food Contamination; Humans; Longitud | 1993 |
Crude oil spill in sea water: an assessment of the risk for bathers correlated to benzo(a)pyrene exposure.
Topics: Administration, Inhalation; Administration, Oral; Adult; Benzo(a)pyrene; Child; Disasters; Humans; I | 1995 |
Surveillance of mortality and cancer incidence among Swedish graphite electrode workers.
Topics: Benzo(a)pyrene; Cohort Studies; Electrodes; Female; Graphite; Humans; Incidence; Laryngeal Neoplasms | 1995 |
[Methods of extrapolating risk from from high to low doses and their effect on determining MAC values].
Topics: Air Pollutants; Benzo(a)pyrene; Carcinogens; Chemical Industry; Coke; Dose-Response Relationship, Dr | 1996 |
[Study of environmental pollution and damage of cytogenetic materials in urban residents].
Topics: Benzo(a)pyrene; Cells, Cultured; China; Chromosome Aberrations; Environmental Pollution; Female; Hum | 1997 |
Misclassification in case-control studies of gene-environment interactions: assessment of bias and sample size.
Topics: Benzo(a)pyrene; Bias; Body Mass Index; Breast Neoplasms; Case-Control Studies; Cocarcinogenesis; Eff | 1999 |
Mutagenicity of benzo[a]pyrene-deoxyadenosine adducts in a sequence context derived from the p53 gene.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Base Sequence; Benzo(a)pyrene; Carcinogens; Codo | 2000 |
Susceptibility of proliferating cells to benzo[a]pyrene-induced homologous recombination in mice.
Topics: Animals; Animals, Newborn; Benzo(a)pyrene; Carcinogens; Cell Division; Eye Color; Gene Deletion; Mic | 2001 |
[Need for studies aimed at the prevention of oncologic diseases].
Topics: Aged; Amino Acids; Benzo(a)pyrene; Carcinogens; Electromagnetic Fields; Humans; Laser Therapy; Neopl | 2001 |
A proposed methodology of cancer risk assessment modeling using biomarkers.
Topics: Animals; Benzo(a)pyrene; Biomarkers; Carcinogens; DNA Adducts; Dose-Response Relationship, Drug; Kin | 2002 |
[Endogenous factors next to exogenous ones should not be overlooked in carcinogenesis].
Topics: Animals; Benzo(a)pyrene; Carcinogens; Humans; Neoplasms; Neoplasms, Experimental; Nitrosamines; Poly | 1991 |
Studies in tobacco carcinogenesis.
Topics: Animals; Benzo(a)pyrene; Catechols; Humans; Neoplasms; Nicotiana; Nitrosamines; Plants, Toxic; Smoke | 1991 |
Selective targeting of p53 gene mutational hotspots in human cancers by etiologically defined carcinogens.
Topics: Aflatoxin B1; Base Sequence; Benzo(a)pyrene; DNA; DNA Fingerprinting; Genes, p53; Humans; Molecular | 1991 |
Effects of biochanin A on metabolism, DNA binding and mutagenicity of benzo[a]pyrene in mammalian cell cultures.
Topics: Animals; Benzo(a)pyrene; Cells, Cultured; Chromatography, High Pressure Liquid; Cricetinae; DNA; DNA | 1991 |
Exposure analysis and assessment for low-risk cancer agents.
Topics: Benzo(a)pyrene; Dose-Response Relationship, Drug; Environmental Exposure; Epidemiologic Methods; Hum | 1990 |
Risk assessment of drinking water in a reservoir contaminated by PAH's originated from road traffic.
Topics: Benz(a)Anthracenes; Benzo(a)pyrene; Humans; Japan; Models, Statistical; Neoplasms; Polycyclic Compou | 1990 |
The 1984 Association Lecture of the Hospital Physicists' Association. Man and his environment.
Topics: Adult; Air Pollutants; Air Pollutants, Radioactive; Benzo(a)pyrene; Carbon Dioxide; Environmental Po | 1985 |
[Evaluation of the carcinogenic hazard in the manufacture of graphite articles].
Topics: Adult; Air Pollutants, Occupational; Benzo(a)pyrene; Carbon; Chronic Disease; Dose-Response Relation | 1989 |
[Carcinogenic and nonspecific harmful factors in the rubber industry].
Topics: Acrylonitrile; Air Pollutants, Occupational; Benzo(a)pyrene; Humans; Neoplasms; Occupational Disease | 1989 |
[Oncohygienic evaluation of the possibility of using active sludge].
Topics: Animal Feed; Animals; Benzo(a)pyrene; Fishes; Food Contamination; Industrial Waste; Neoplasms; Paper | 1988 |
[Tar, bitumen, benzopyrene--an assessment of health risk at the work site].
Topics: Benzo(a)pyrene; Carcinogenicity Tests; Coal Tar; Environmental Exposure; Humans; Hydrocarbons; Neopl | 1988 |
Molecular cancer epidemiology: a new tool in cancer prevention.
Topics: Benzo(a)pyrene; Cisplatin; DNA; Dose-Response Relationship, Drug; Environmental Monitoring; Genetic | 1987 |
The role of metabolism in benzo(a)pyrene carcinogenesis.
Topics: Animals; Benzo(a)pyrene; Biotransformation; Cell Line; Chromatography, High Pressure Liquid; Genetic | 1986 |
[Analysis and evaluation of carcinogenic aromatic polycyclic hydrocarbons].
Topics: Benzo(a)pyrene; Food Contamination; Germany, East; Humans; Neoplasms | 1986 |
Coal-tars and derived products.
Topics: Animals; Benzo(a)pyrene; Carcinogens; Chemical Phenomena; Chemistry; Coal Tar; Hot Temperature; Huma | 1985 |
Animal studies and prediction of human tumors can be aided by graphical sorting of animal data: neoplastic risk from B(a)P, benzene, benzidine, and chromium.
Topics: Animals; Benzene; Benzidines; Benzo(a)pyrene; Chromium; Computers; Cricetinae; Dose-Response Relatio | 1985 |
[Metabolic mechanisms of long-term effects of environmental chemical factors--carcinogenic, embryotoxic, gonadotoxic, mutagenic and gerontologic effects].
Topics: Aging; Air Pollutants; Animals; Benzo(a)pyrene; Dimethylnitrosamine; Embryo Loss; Female; Humans; Ma | 1985 |
Evolution and cancer.
Topics: Adenoviruses, Human; Alkylation; Animals; Benzo(a)pyrene; Biological Evolution; Carcinogens; Cell Di | 1985 |
Formation and persistence of benzo(a)pyrene metabolite-DNA adducts.
Topics: Animals; Benzo(a)pyrene; Carcinogens; DNA; DNA Repair; Humans; Kinetics; Mice; Neoplasms; Polycyclic | 1985 |