Page last updated: 2024-10-23

benzo(a)pyrene and Neoplasm Metastasis

benzo(a)pyrene has been researched along with Neoplasm Metastasis in 11 studies

Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.

Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.

Research Excerpts

ExcerptRelevanceReference
"Our review of hallmarks of cancer and their temporal sequence, based on mutational spectra in biopsies from different cancer sites, allowed us to propose a hypothetical temporal sequence of the hallmarks."2.58Filling the gap between chemical carcinogenesis and the hallmarks of cancer: A temporal perspective. ( Degli Esposti, D; Demetriou, CA; Pullen Fedinick, K; Robinson, O; Russo, F; Vineis, P, 2018)
"Metastasis is the leading cause of deaths in patients with breast cancer."1.42Effects of exposure to benzo[a]pyrene on metastasis of breast cancer are mediated through ROS-ERK-MMP9 axis signaling. ( Dai, C; Guo, J; Ji, W; Song, L; Xu, Y; Zhan, L, 2015)
"With the onset of metastasis, HABP1 overexpression was confined to metastatic islands, while it disappeared gradually from the surrounding mass."1.32Differential expression of Hyaluronic Acid Binding Protein 1 (HABP1)/P32/C1QBP during progression of epidermal carcinoma. ( Chowdhury, AR; Datta, K; Ghosh, I; Rajeswari, MR, 2004)
"None of the mutations found only in metastases were located in exon 8."1.29Lack of concordant p53 mutations in some paired primary and metastatic mouse squamous cell carcinomas induced by chemical carcinogenesis. ( Bauer, B; Goodrow, TL; Klein-Szanto, AJ; Mitsunaga, S; Zhang, SY, 1995)
"Spontaneous metastasis incidence was low for both controls and treated cells; however, almost all animals (15/16) injected i."1.28Induction of invasive and experimental metastasis potential in BALB/c 3T3 cells by benzo(a)pyrene transformation. ( Albini, A; Carlone, S; Colacci, A; De Giovanni, C; Grilli, S; Lollini, PL; Melchiori, A; Parodi, S, 1992)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's3 (27.27)18.2507
2000's1 (9.09)29.6817
2010's5 (45.45)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Li, L1
Chen, J1
Wang, Y1
Zhou, C1
Ma, X1
Fu, J1
Yao, B1
Zhao, P1
Demetriou, CA1
Degli Esposti, D1
Pullen Fedinick, K1
Russo, F1
Robinson, O1
Vineis, P1
Jungnickel, H1
Potratz, S1
Baumann, S1
Tarnow, P1
von Bergen, M1
Luch, A1
Guo, J1
Xu, Y1
Ji, W1
Song, L1
Dai, C1
Zhan, L1
Wei, Y1
Zhao, L1
He, W1
Yang, J1
Geng, C1
Chen, Y1
Liu, T1
Chen, H2
Li, Y1
Ramya, D1
Manjamalai, A1
Berlin Grace, VM1
Ghosh, I1
Chowdhury, AR1
Rajeswari, MR1
Datta, K1
Honn, KV1
Bockman, RS1
Marnett, LJ1
Zhang, SY1
Bauer, B1
Mitsunaga, S1
Goodrow, TL1
Klein-Szanto, AJ1
Melchiori, A1
Colacci, A1
Lollini, PL1
De Giovanni, C1
Carlone, S1
Grilli, S1
Parodi, S1
Albini, A1
Gensler, HL1

Reviews

2 reviews available for benzo(a)pyrene and Neoplasm Metastasis

ArticleYear
Filling the gap between chemical carcinogenesis and the hallmarks of cancer: A temporal perspective.
    European journal of clinical investigation, 2018, Volume: 48, Issue:6

    Topics: Benzo(a)pyrene; Carcinogenesis; Carcinogens; Cell Death; Cell Proliferation; Cell Survival; Humans;

2018
Prostaglandins and cancer: a review of tumor initiation through tumor metastasis.
    Prostaglandins, 1981, Volume: 21, Issue:5

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Differentiation; Cell Division; Cell Transf

1981

Other Studies

9 other studies available for benzo(a)pyrene and Neoplasm Metastasis

ArticleYear
MicroRNA expression profiling and the role of ALCAM modulating tumor growth and metastasis in benzo[a]pyrene-transformed 16HBE cells.
    Toxicology, 2020, Volume: 442

    Topics: Animals; Antigens, CD; Benzo(a)pyrene; Carcinogens; Cell Adhesion Molecules, Neuronal; Cell Line, Tu

2020
Identification of lipidomic biomarkers for coexposure to subtoxic doses of benzo[a]pyrene and cadmium: the toxicological cascade biomarker approach.
    Environmental science & technology, 2014, Sep-02, Volume: 48, Issue:17

    Topics: Benzo(a)pyrene; Biomarkers, Tumor; Cadmium; Carcinogenesis; Humans; Lipid Metabolism; MCF-7 Cells; N

2014
Effects of exposure to benzo[a]pyrene on metastasis of breast cancer are mediated through ROS-ERK-MMP9 axis signaling.
    Toxicology letters, 2015, May-05, Volume: 234, Issue:3

    Topics: Animals; Benzo(a)pyrene; Breast Neoplasms; Carcinogens; Cell Movement; Female; Humans; Mammary Neopl

2015
Benzo[a]pyrene promotes gastric cancer cell proliferation and metastasis likely through the Aryl hydrocarbon receptor and ERK-dependent induction of MMP9 and c-myc.
    International journal of oncology, 2016, Volume: 49, Issue:5

    Topics: Basic Helix-Loop-Helix Transcription Factors; Benzo(a)pyrene; Blotting, Western; Cell Movement; Cell

2016
Chemoprotective effect of all-trans retinoic acid (ATRA) on oxidative stress and lung metastasis induced by benzo(a)pyrene.
    Immunopharmacology and immunotoxicology, 2012, Volume: 34, Issue:2

    Topics: Animals; Ascorbic Acid; Behavior, Animal; Benzo(a)pyrene; Catalase; Chemoprevention; Glutathione; Gl

2012
Differential expression of Hyaluronic Acid Binding Protein 1 (HABP1)/P32/C1QBP during progression of epidermal carcinoma.
    Molecular and cellular biochemistry, 2004, Volume: 267, Issue:1-2

    Topics: Animals; Benzo(a)pyrene; Carcinogens; Carcinoma; Disease Progression; Gene Expression Profiling; Gen

2004
Lack of concordant p53 mutations in some paired primary and metastatic mouse squamous cell carcinomas induced by chemical carcinogenesis.
    Molecular carcinogenesis, 1995, Volume: 12, Issue:2

    Topics: Animals; Base Sequence; Benzo(a)pyrene; Carcinoma, Squamous Cell; DNA Primers; DNA, Neoplasm; Genes,

1995
Induction of invasive and experimental metastasis potential in BALB/c 3T3 cells by benzo(a)pyrene transformation.
    Invasion & metastasis, 1992, Volume: 12, Issue:1

    Topics: 3T3 Cells; Animals; Benzo(a)pyrene; Cell Division; Cell Transformation, Neoplastic; Chemotaxis; Clon

1992
Enhanced growth and experimental metastasis of chemically induced tumor in ultraviolet irradiated syngeneic mice.
    Photochemistry and photobiology, 1991, Volume: 53, Issue:5

    Topics: Animals; Benzo(a)pyrene; Cell Division; Female; Fibrosarcoma; Lung Neoplasms; Mice; Mice, Inbred BAL

1991