benzo(a)pyrene has been researched along with Mouth Neoplasms in 25 studies
Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Mouth Neoplasms: Tumors or cancer of the MOUTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oral squamous cell carcinoma (OSCC) is usually preceded by the oral premalignant lesions, mainly oral leukoplakia (OLK) after repeated insults of carcinogens, tobacco." | 1.42 | Establishment of a new OSCC cell line derived from OLK and identification of malignant transformation-related proteins by differential proteomics approach. ( Chen, Z; Dong, L; Dong, Y; Fang, F; Fu, M; Guo, X; Li, J; Liu, C; Liu, X; Ma, G; Ma, X; Shao, S; Xiao, J; Xue, L; Yang, X; Yu, L; Zhan, Q; Zhang, L; Zhang, W; Zhang, Y; Zhao, Q, 2015) |
| "At 47 weeks, oral squamous cell carcinomas (OSCC) were found in 31% of the high-dose B6C3F1 group." | 1.38 | Mutagenesis and carcinogenesis induced by dibenzo[a,l]pyrene in the mouse oral cavity: a potential new model for oral cancer. ( Ahn, K; Aliaga, C; Amin, S; Bruggeman, R; Chen, KM; Cooper, T; DelTondo, J; El-Bayoumy, K; Guttenplan, JB; Jiang, K; Kosinska, W; Sharma, AK; Sun, YW; Zhang, SM; Zhao, ZL, 2012) |
| "Oral squamous cell carcinoma (OSCC) is the most common malignant tumor in the oral and maxillofacial region." | 1.35 | Characteristics of a cancerous cell line, HIOEC-B(a)P-96, induced by benzo(a)pyrene from human immortalized oral epithelial cell line. ( Chen, WT; Pan, HY; Yang, X; Ye, DX; Zhang, L; Zhang, ZY; Zhong, LP; Zhou, XJ, 2008) |
| "B(a)P may induce HIOEC cells to be oral squamous cell carcinoma (OSCC) carcinogenetic cells." | 1.33 | [The establishment of a carcinogenesis model of oral squamous cell carcinoma in vitro]. ( Chen, WT; He, RG; Li, J; Pan, HY; Zhang, ZY; Zhou, XJ, 2006) |
| " This study investigated whether HC modulates cigarette carcinogen benzo[a]pyrene (B[a]P)-mediated toxic effects." | 1.32 | Hydroxychavicol modulates benzo[a]pyrene-induced genotoxicity through induction of dihydrodiol dehydrogenase. ( Chang, KW; Chi, CW; Liu, TY; Tang, DW, 2004) |
| "In patients with cancers known to be related to smoking, 46% (n = 50) showed higher levels of glutathione S-transferase class mu." | 1.29 | Human leukocyte glutathione S-transferase isozyme (class mu) and susceptibility to smoking-related cancers. ( Krishna, TP; Krishnaswamy, K; Soni, MG, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (8.00) | 18.7374 |
| 1990's | 5 (20.00) | 18.2507 |
| 2000's | 12 (48.00) | 29.6817 |
| 2010's | 3 (12.00) | 24.3611 |
| 2020's | 3 (12.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, KM | 2 |
| Sun, YW | 2 |
| Krebs, NM | 1 |
| Sun, D | 1 |
| Krzeminski, J | 1 |
| Reinhart, L | 1 |
| Gowda, K | 1 |
| Amin, S | 2 |
| Mallery, S | 1 |
| Richie, JP | 2 |
| El-Bayoumy, K | 2 |
| He, H | 1 |
| Huang, Y | 1 |
| Lu, Y | 1 |
| Wang, X | 1 |
| Ni, H | 1 |
| Wu, Y | 1 |
| Xia, D | 1 |
| Ye, D | 1 |
| Ding, J | 1 |
| Mao, Y | 1 |
| Teng, Y | 1 |
| R, H | 1 |
| Ramani, P | 1 |
| Ramanathan, A | 1 |
| R, JM | 1 |
| S, G | 1 |
| Ramasubramanian, A | 1 |
| K, M | 1 |
| Dong, Y | 1 |
| Zhao, Q | 1 |
| Ma, X | 1 |
| Ma, G | 1 |
| Liu, C | 1 |
| Chen, Z | 1 |
| Yu, L | 1 |
| Liu, X | 1 |
| Zhang, Y | 1 |
| Shao, S | 1 |
| Xiao, J | 1 |
| Li, J | 3 |
| Zhang, W | 1 |
| Fu, M | 1 |
| Dong, L | 1 |
| Yang, X | 2 |
| Guo, X | 1 |
| Xue, L | 1 |
| Fang, F | 1 |
| Zhan, Q | 1 |
| Zhang, L | 2 |
| Li, JZ | 1 |
| Pan, HY | 4 |
| Zheng, JW | 1 |
| Zhou, XJ | 4 |
| Zhang, P | 2 |
| Chen, WT | 4 |
| Zhang, ZY | 4 |
| Chi, AC | 1 |
| Appleton, K | 1 |
| Henriod, JB | 1 |
| Krayer, JW | 1 |
| Marlow, NM | 1 |
| Bandyopadhyay, D | 1 |
| Sigmon, RC | 1 |
| Kurtz, DT | 1 |
| Brandon, JL | 1 |
| Conti, CJ | 1 |
| Goldstein, LS | 1 |
| DiGiovanni, J | 1 |
| Gimenez-Conti, IB | 1 |
| Warnakulasuriya, S | 1 |
| Dietrich, T | 1 |
| Bornstein, MM | 1 |
| Casals Peidró, E | 1 |
| Preshaw, PM | 1 |
| Walter, C | 1 |
| Wennström, JL | 1 |
| Bergström, J | 1 |
| Guttenplan, JB | 1 |
| Kosinska, W | 1 |
| Zhao, ZL | 1 |
| Aliaga, C | 1 |
| DelTondo, J | 1 |
| Cooper, T | 1 |
| Zhang, SM | 1 |
| Jiang, K | 1 |
| Bruggeman, R | 1 |
| Sharma, AK | 1 |
| Ahn, K | 1 |
| Hung, KF | 1 |
| Lin, SC | 1 |
| Liu, CJ | 1 |
| Chang, CS | 1 |
| Chang, KW | 2 |
| Kao, SY | 1 |
| Almahmeed, T | 1 |
| Boyle, JO | 1 |
| Cohen, EG | 1 |
| Carew, JF | 1 |
| Du, B | 1 |
| Altorki, NK | 1 |
| Kopelovich, L | 1 |
| Fang, JL | 1 |
| Lazarus, P | 2 |
| Subbaramaiah, K | 1 |
| Dannenberg, AJ | 1 |
| Tang, DW | 1 |
| Chi, CW | 1 |
| Liu, TY | 1 |
| Wen, X | 1 |
| Walle, T | 3 |
| Walle, UK | 2 |
| Sedmera, D | 1 |
| Klausner, M | 1 |
| He, RG | 1 |
| Zhong, LP | 1 |
| Ye, DX | 1 |
| Rao, AR | 1 |
| Soni, MG | 1 |
| Krishna, TP | 1 |
| Krishnaswamy, K | 1 |
| Park, NH | 1 |
| Gujuluva, CN | 1 |
| Baek, JH | 1 |
| Cherrick, HM | 1 |
| Shin, KH | 1 |
| Min, BM | 1 |
| Azuine, MA | 1 |
| Bhide, SV | 1 |
| Sheikh, SN | 1 |
| Ren, Q | 1 |
| Schantz, SP | 1 |
| Stern, JC | 1 |
| Park, JY | 1 |
| Meng, CL | 1 |
| Shyu, KW | 1 |
| Hoffmann, D | 1 |
| Harley, NH | 1 |
| Fisenne, I | 1 |
| Adams, JD | 1 |
| Brunnemann, KD | 1 |
1 review available for benzo(a)pyrene and Mouth Neoplasms
| Article | Year |
|---|---|
Oral health risks of tobacco use and effects of cessation.
Topics: Benzo(a)pyrene; Carcinogens; Dental Caries; DNA Damage; Humans; Leukoplakia, Oral; Mouth Neoplasms; | 2010 |
24 other studies available for benzo(a)pyrene and Mouth Neoplasms
| Article | Year |
|---|---|
Detection of DNA adducts derived from the tobacco carcinogens, benzo[a]pyrene and dibenzo[def,p]chrysene in human oral buccal cells.
Topics: Benzo(a)pyrene; Carcinogens; Chromatography, Liquid; Chrysenes; DNA Adducts; Humans; Mouth Mucosa; M | 2022 |
Effect of benzo[a]pyrene on proliferation and metastasis of oral squamous cell carcinoma cells: A transcriptome analysis based on RNA-seq.
Topics: Benzo(a)pyrene; Carcinogens; Cell Proliferation; Dimethyl Sulfoxide; Gene Expression Profiling; Huma | 2022 |
CYP2 C9 polymorphism among patients with oral squamous cell carcinoma and its role in altering the metabolism of benzo[a]pyrene.
Topics: Alleles; Benzo(a)pyrene; Carcinoma, Squamous Cell; Case-Control Studies; Humans; Molecular Docking S | 2020 |
Establishment of a new OSCC cell line derived from OLK and identification of malignant transformation-related proteins by differential proteomics approach.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Apoptosis; Benzo(a)pyrene; Biomarkers, Tumor; Carcinogens; Carcino | 2015 |
Benzo (a) pyrene induced tumorigenesity of human immortalized oral epithelial cells: transcription profiling.
Topics: Benzo(a)pyrene; Cell Transformation, Neoplastic; Cells, Cultured; Connexin 43; Gene Expression Profi | 2008 |
Differential induction of CYP1A1 and CYP1B1 by benzo[a]pyrene in oral squamous cell carcinoma cell lines and by tobacco smoking in oral mucosa.
Topics: Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Carcinoma, Squamous Cell; Cytochrome P-450 CYP1A1; Cy | 2009 |
Carcinogenic effects of MGP-7 and B[a]P on the hamster cheek pouch.
Topics: Animals; Benzo(a)pyrene; Carcinogenicity Tests; Carcinoma, Squamous Cell; Cell Proliferation; Cheek; | 2009 |
Mutagenesis and carcinogenesis induced by dibenzo[a,l]pyrene in the mouse oral cavity: a potential new model for oral cancer.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogenicity Tests; Carcinogens; Carcinoma, Squamous Cell; | 2012 |
The biphasic differential expression of the cellular membrane protein, caveolin-1, in oral carcinogenesis.
Topics: Adult; Age Factors; Aged; Areca; Benzo(a)pyrene; Biomarkers, Tumor; Carcinoma, Squamous Cell; Caveol | 2003 |
Benzo[a]pyrene phenols are more potent inducers of CYP1A1, CYP1B1 and COX-2 than benzo[a]pyrene glucuronides in cell lines derived from the human aerodigestive tract.
Topics: Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Carcinoma, Squamous Cell; Cell Line; Cyclooxygenase 2 | 2004 |
Hydroxychavicol modulates benzo[a]pyrene-induced genotoxicity through induction of dihydrodiol dehydrogenase.
Topics: Areca; Benzo(a)pyrene; Blotting, Western; Carcinogens; Carcinoma, Squamous Cell; Cyclooxygenase 2; D | 2004 |
Preferential induction of CYP1B1 by benzo[a]pyrene in human oral epithelial cells: impact on DNA adduct formation and prevention by polyphenols.
Topics: Anticarcinogenic Agents; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Carcinoma, Squamous Cell; Ce | 2005 |
Benzo[A]pyrene-induced oral carcinogenesis and chemoprevention: studies in bioengineered human tissue.
Topics: Anticarcinogenic Agents; Benzo(a)pyrene; Carcinogens; Cytochrome P-450 Enzyme System; DNA Adducts; F | 2006 |
[The establishment of a carcinogenesis model of oral squamous cell carcinoma in vitro].
Topics: Animals; Benzo(a)pyrene; Carcinoma, Squamous Cell; Cell Line, Transformed; Cell Line, Tumor; Cell Tr | 2006 |
[The establishment of B(a)P and TPA transformed cell line and its biological characteristics].
Topics: Benzo(a)pyrene; Carcinogens; Carcinoma, Squamous Cell; Cell Line; Cell Line, Transformed; Cell Line, | 2006 |
Novel methoxylated flavone inhibitors of cytochrome P450 1B1 in SCC-9 human oral cancer cells.
Topics: Analysis of Variance; Anticarcinogenic Agents; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Carcin | 2007 |
Characteristics of a cancerous cell line, HIOEC-B(a)P-96, induced by benzo(a)pyrene from human immortalized oral epithelial cell line.
Topics: Animals; Benzo(a)pyrene; Blotting, Western; Carcinogens; Carcinoma, Squamous Cell; Cell Line, Transf | 2008 |
Modifying influences of betel quid ingredients on B(a)P-induced carcinogenesis in the buccal pouch of hamster.
Topics: Animals; Areca; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cheek; Cricetinae; Female; Mesocricetus; | 1984 |
Human leukocyte glutathione S-transferase isozyme (class mu) and susceptibility to smoking-related cancers.
Topics: Adult; Animals; Benzo(a)pyrene; Biomarkers; Disease Susceptibility; Female; Glutathione Transferase; | 1995 |
Combined oral carcinogenicity of HPV-16 and benzo(a)pyrene: an in vitro multistep carcinogenesis model.
Topics: Animals; Base Sequence; Benzo(a)pyrene; Carcinoma, Squamous Cell; Cell Division; Cell Line, Transfor | 1995 |
Adjuvant chemoprevention of experimental cancer: catechin and dietary turmeric in forestomach and oral cancer models.
Topics: Adjuvants, Pharmaceutic; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Catechin; Cricetinae; Cur | 1994 |
p53, but not p16 mutations in oral squamous cell carcinomas are associated with specific CYP1A1 and GSTM1 polymorphic genotypes and patient tobacco use.
Topics: Benzo(a)pyrene; Carcinoma, Squamous Cell; Cyclin-Dependent Kinase Inhibitor p16; Cytochrome P-450 CY | 1998 |
Inhibition of experimental carcinogenesis by painting with garlic extract.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Analysis of Variance; Animals; Benzo(a)pyrene; Cheek; Cricetinae; | 1990 |
Carcinogenic agents in snuff.
Topics: Benzo(a)pyrene; Carcinogens; Humans; Mouth Neoplasms; Nicotiana; Nitrosamines; Pharyngeal Neoplasms; | 1986 |