benzo(a)pyrene has been researched along with Intestinal Neoplasms in 6 studies
Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Intestinal Neoplasms: Tumors or cancer of the INTESTINES.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Following high dosage of oral BaP (125 mg/kg/day), ablation of the mouse Cyp1a1 gene causes immunosuppression and death within ∼28 days, whereas Cyp1(+/+) wild-type mice remain healthy for >12 months on this regimen." | 1.36 | Oral benzo[a]pyrene-induced cancer: two distinct types in different target organs depend on the mouse Cyp1 genotype. ( Chen, J; Dragin, N; Gonzalez, FJ; Johansson, E; Miller, ML; Nebert, DW; Rubio, CA; Shi, Z; Stringer, KF; Uno, S, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nebert, DW | 2 |
| Shi, Z | 2 |
| Gálvez-Peralta, M | 1 |
| Uno, S | 2 |
| Dragin, N | 2 |
| Halberg, RB | 1 |
| Larsen, MC | 1 |
| Elmergreen, TL | 1 |
| Ko, AY | 1 |
| Irving, AA | 1 |
| Clipson, L | 1 |
| Jefcoate, CR | 1 |
| Miller, ML | 1 |
| Stringer, KF | 1 |
| Johansson, E | 1 |
| Chen, J | 1 |
| Gonzalez, FJ | 1 |
| Rubio, CA | 1 |
| Katiyar, SK | 1 |
| Agarwal, R | 1 |
| Zaim, MT | 1 |
| Mukhtar, H | 1 |
| Patel, HR | 1 |
| Hewer, A | 1 |
| Phillips, DH | 1 |
| Hayes, JD | 1 |
| Wolf, CR | 1 |
| Campbell, FC | 1 |
| Culp, SJ | 1 |
| Gaylor, DW | 1 |
| Sheldon, WG | 1 |
| Goldstein, LS | 1 |
| Beland, FA | 1 |
1 review available for benzo(a)pyrene and Intestinal Neoplasms
| Article | Year |
|---|---|
Oral benzo[a]pyrene: understanding pharmacokinetics, detoxication, and consequences--Cyp1 knockout mouse lines as a paradigm.
Topics: Administration, Oral; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Carcinogens, Environme | 2013 |
5 other studies available for benzo(a)pyrene and Intestinal Neoplasms
| Article | Year |
|---|---|
Cyp1b1 exerts opposing effects on intestinal tumorigenesis via exogenous and endogenous substrates.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; beta Caten | 2008 |
Oral benzo[a]pyrene-induced cancer: two distinct types in different target organs depend on the mouse Cyp1 genotype.
Topics: Adenocarcinoma; Administration, Oral; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Carcin | 2010 |
Protection against N-nitrosodiethylamine and benzo[a]pyrene-induced forestomach and lung tumorigenesis in A/J mice by green tea.
Topics: Animals; Benzo(a)pyrene; Diethylnitrosamine; Female; Intestinal Neoplasms; Lung Neoplasms; Mice; Mic | 1993 |
Metabolic competence and susceptibility of intestinal epithelium to genotoxic injury during regeneration.
Topics: Animals; Benzo(a)pyrene; DNA Adducts; Intestinal Neoplasms; Intestines; Male; Mutagens; Rats; Rats, | 1997 |
A comparison of the tumors induced by coal tar and benzo[a]pyrene in a 2-year bioassay.
Topics: Adenoma; Animals; Benzo(a)pyrene; Biological Assay; Carcinoma; Coal Tar; Diet; Female; Industrial Wa | 1998 |