benzo(a)pyrene has been researched along with Hyperplasia in 24 studies
Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Application of rosemary to mouse skin also inhibited TPA-induced ornithine decarboxylase activity, TPA-induced inflammation, arachidonic acid-induced inflammation, TPA-induced hyperplasia, and TPA-induced tumor promotion." | 3.69 | Inhibition of skin tumorigenesis by rosemary and its constituents carnosol and ursolic acid. ( Conney, AH; Ferraro, T; Georgiadis, C; Ho, CT; Huang, MT; Laskin, JD; Lou, YR; Ma, W; Stauber, K; Wang, ZY, 1994) |
| "Lung cancer has emerged as one of the leading causes of cancer death in most developed and many developing countries of the world." | 1.33 | Black tea extract can modulate protein expression of H-ras, c-Myc, p53, and Bcl-2 genes during pulmonary hyperplasia, dysplasia, and carcinoma in situ. ( Banerjee, S; Das, S; Ganguly, C; Manna, S; Panda, CK; Saha, P, 2005) |
| "Incidence of tumors (predominantly squamous carcinomas) and mortality was 100% by 36 weeks in all environments in the high-dose group." | 1.26 | Effect of temperature on benzo[a]pyrene-induced hyperplastic and neoplastic skin lesions in mice. ( Weisbrode, SE; Weiss, HS, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (37.50) | 18.7374 |
| 1990's | 8 (33.33) | 18.2507 |
| 2000's | 6 (25.00) | 29.6817 |
| 2010's | 1 (4.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Burnett-Hartman, AN | 1 |
| Newcomb, PA | 1 |
| Mandelson, MT | 1 |
| Adams, SV | 1 |
| Wernli, KJ | 1 |
| Shadman, M | 1 |
| Wurscher, MA | 1 |
| Makar, KW | 1 |
| Estensen, RD | 1 |
| Jordan, MM | 1 |
| Wiedmann, TS | 1 |
| Galbraith, AR | 1 |
| Steele, VE | 1 |
| Wattenberg, LW | 1 |
| Bae, JS | 1 |
| Jang, KH | 1 |
| Yim, H | 1 |
| Park, SC | 1 |
| Jin, HK | 1 |
| Saha, P | 1 |
| Banerjee, S | 2 |
| Ganguly, C | 1 |
| Manna, S | 1 |
| Panda, CK | 2 |
| Das, S | 2 |
| Yuen, BB | 1 |
| Wong, CK | 1 |
| Woo, NY | 1 |
| Au, DW | 1 |
| Weisbrode, SE | 1 |
| Weiss, HS | 1 |
| Hasegawa, R | 2 |
| Tatematsu, M | 2 |
| Tsuda, H | 2 |
| Shirai, T | 1 |
| Hagiwara, A | 1 |
| Ito, N | 2 |
| Imaida, K | 1 |
| Wang, CJ | 1 |
| Lee, MJ | 1 |
| Chang, MC | 1 |
| Lin, JK | 1 |
| Huang, MT | 3 |
| Ho, CT | 2 |
| Wang, ZY | 2 |
| Ferraro, T | 2 |
| Lou, YR | 3 |
| Stauber, K | 1 |
| Ma, W | 1 |
| Georgiadis, C | 1 |
| Laskin, JD | 2 |
| Conney, AH | 2 |
| Silva, RA | 2 |
| Muñoz, SE | 2 |
| Guzmán, CA | 1 |
| Eynard, AR | 2 |
| Evnard, AR | 1 |
| Mitsunaga, S | 1 |
| Clapper, M | 1 |
| Litwin, S | 2 |
| Watts, P | 1 |
| Bauer, B | 1 |
| Klein-Szanto, AJ | 2 |
| Hakura, A | 1 |
| Sonoda, J | 1 |
| Tsutsui, Y | 1 |
| Mikami, T | 1 |
| Imade, T | 1 |
| Shimada, M | 1 |
| Yaguchi, S | 1 |
| Yamanaka, M | 1 |
| Tomimatsu, M | 1 |
| Tsukidate, K | 1 |
| Wei, SJ | 1 |
| Chang, RL | 1 |
| Merkler, KA | 1 |
| Gwynne, M | 1 |
| Cui, XX | 1 |
| Murthy, B | 1 |
| Xie, JG | 1 |
| Lu, YP | 1 |
| Jerina, DM | 1 |
| Perez, CA | 1 |
| Ura, H | 1 |
| Momiki, S | 1 |
| Bonfil, D | 1 |
| Finnegan-Olive, T | 1 |
| Mitchell, JM | 1 |
| Newmark, H | 1 |
| Yang, CS | 1 |
| Jia, XS | 1 |
| Ren, J | 1 |
| He, MC | 1 |
| Hun, SM | 1 |
| Zhang, L | 1 |
| Lian, CH | 1 |
| Lasnitzki, I | 1 |
| Bollag, W | 1 |
| Marchok, AC | 1 |
| Arnseth, LM | 1 |
| Reynders, JB | 1 |
| Immel, HR | 1 |
| Scherrenberg, PM | 1 |
| Feron, VJ | 1 |
| Beems, RB | 1 |
24 other studies available for benzo(a)pyrene and Hyperplasia
| Article | Year |
|---|---|
Colorectal polyp type and the association with charred meat consumption, smoking, and microsomal epoxide hydrolase polymorphisms.
Topics: Adult; Aged; Animals; Benzo(a)pyrene; Colonic Polyps; Colonoscopy; Colorectal Neoplasms; Cooking; Ep | 2011 |
Effect of chemopreventive agents on separate stages of progression of benzo[alpha]pyrene induced lung tumors in A/J mice.
Topics: Adenoma; Aerosols; Animals; Anti-Inflammatory Agents; Benzo(a)pyrene; Budesonide; Carcinogens; Disea | 2004 |
Inhibitory effects of polysaccharides isolated from Phellinus gilvus on benzo(a)pyrene-induced forestomach carcinogenesis in mice.
Topics: Agaricales; Animals; Antineoplastic Agents; Benzo(a)pyrene; Down-Regulation; Female; Gene Expression | 2005 |
Black tea extract can modulate protein expression of H-ras, c-Myc, p53, and Bcl-2 genes during pulmonary hyperplasia, dysplasia, and carcinoma in situ.
Topics: Animals; Animals, Newborn; Anticarcinogenic Agents; Apoptosis; Benzo(a)pyrene; Biflavonoids; Carcino | 2005 |
Clove (Syzygium aromaticum L.), a potential chemopreventive agent for lung cancer.
Topics: Animals; Animals, Newborn; Apoptosis; bcl-2-Associated X Protein; Benzo(a)pyrene; Carcinoma in Situ; | 2006 |
Induction and recovery of morphofunctional changes in the intestine of juvenile carnivorous fish (Epinephelus coioides) upon exposure to foodborne benzo[a]pyrene.
Topics: Animal Feed; Animals; Bass; Benzo(a)pyrene; Body Weight; Bromodeoxyuridine; Cell Death; Cell Prolife | 2007 |
Effect of temperature on benzo[a]pyrene-induced hyperplastic and neoplastic skin lesions in mice.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; F | 1981 |
Induction of hyperplastic liver nodules in hepatectomized rats treated with 3'-methyl-4-dimethylaminoazobenzene, benzo[a]pyrene or phenobarbital before or after exposure to N-2-fluorenylacetamide.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Benzopyrenes; Carbon Tetrachloride; Hepatectomy; Hyp | 1982 |
Survey of various chemicals for initiating and promoting activities in a short-term in vivo system based on generation of hyperplastic liver nodules in rats.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Drug Evaluation, Preclinical; Ethionine; Hyperpl | 1983 |
Inhibition of tumor promotion in benzo[a]pyrene-initiated CD-1 mouse skin by crocetin.
Topics: Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carotenoids; Edema; Enzyme Induction; Female; Hydr | 1995 |
Inhibition of skin tumorigenesis by rosemary and its constituents carnosol and ursolic acid.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Abietanes; Animals; Anticarcinogenic Agents; Antioxidants; Arachid | 1994 |
Effects of dietary n-3, n-6 and n-9 polyunsaturated fatty acids on benzo(a)pyrene-induced forestomach tumorigenesis in C57BL6J mice.
Topics: Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carcinoma, Squamous Cell; Cod Liver Oil; Corn Oil; | 1995 |
Chemopreventive effect of difluoromethylornithine (DFMO) on mouse skin squamous cell carcinomas induced by benzo(a)pyrene.
Topics: Animals; Benzo(a)pyrene; Carcinogens; Carcinoma, Squamous Cell; Eflornithine; Female; Hyperplasia; M | 1997 |
Toxicity profile of benzo[a]pyrene in the male LacZ transgenic mouse (MutaMouse) following oral administration for 5 consecutive days.
Topics: Administration, Oral; Animals; Benzo(a)pyrene; Body Weight; Carcinogenicity Tests; Carcinogens; Carc | 1998 |
Dose-dependent mutation profile in the c-Ha-ras proto-oncogene of skin tumors in mice initiated with benzo[a]pyrene.
Topics: Administration, Cutaneous; Amino Acid Substitution; Animals; Benzo(a)pyrene; Carcinogens; Carcinoma | 1999 |
Effects of dietary fat on benz-a-pyrene-induced forestomach tumorigenesis in mice chronically exposed to arsenic.
Topics: Animals; Arsenic; Benzo(a)pyrene; Carcinogens; Dietary Fats; Disease Models, Animal; Drug Interactio | 2000 |
Effects of formaldehyde on xenotransplanted human respiratory epithelium.
Topics: Animals; Benzo(a)pyrene; Bronchi; Cocarcinogenesis; Dose-Response Relationship, Drug; Epithelium; Fo | 1992 |
Inhibitory effect of topical application of a green tea polyphenol fraction on tumor initiation and promotion in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Benzo(a)pyrene; Edema; Enzyme In | 1992 |
[Ultrastructural and histogenetic studies on experimental pulmonary carcinoma].
Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Animals; Benzo(a)pyrene; Carcinoma, Squamous Ce | 1987 |
[Ultrastructural study on the tracheal epithelium of hamsters induced by chemical carcinogen].
Topics: Animals; Benzo(a)pyrene; Cell Transformation, Neoplastic; Cricetinae; Culture Techniques; Epithelium | 1987 |
In vitro alterations of tracheal epithelium of hamsters by carcinogens in organ culture.
Topics: Animals; Benzo(a)pyrene; Carcinogens; Cocarcinogenesis; Cricetinae; Epithelium; Hyperplasia; Mesocri | 1987 |
Prevention and reversal by a non-polar arotinoid (Ro 15-0778) of 3,4-benzpyrene- and cigarette smoke condensate-induced hyperplasia and metaplasia of rodent respiratory epithelia grown in vitro.
Topics: Animals; Benzo(a)pyrene; Epithelium; Hyperplasia; Lung; Metaplasia; Mice; Naphthalenes; Nicotiana; O | 1987 |
Quantitation of growth-altered cell populations (tumor-initiation sites) induced in open-ended rat tracheal implants by split doses of benzo[a]pyrene.
Topics: Animals; Benzo(a)pyrene; Cell Transformation, Neoplastic; Cells, Cultured; Dose-Response Relationshi | 1987 |
Respiratory tract tumors in hamsters after severe focal injury to the trachea and intratracheal instillation of benzo[a]pyrene.
Topics: Animals; Benzo(a)pyrene; Body Weight; Bronchial Neoplasms; Cocarcinogenesis; Cricetinae; Electrocoag | 1985 |