benzo(a)pyrene has been researched along with Glucosephosphate Dehydrogenase Deficiency in 6 studies
Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Glucosephosphate Dehydrogenase Deficiency: A disease-producing enzyme deficiency subject to many variants, some of which cause a deficiency of GLUCOSE-6-PHOSPHATE DEHYDROGENASE activity in erythrocytes, leading to hemolytic anemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In contrast, no difference between the normal and the deficient fibroblasts exists as regards the toxic effect of methylnitrosourea, a carcinogen that does not need metabolic activation." | 1.27 | Modulatory effect of glucose-6-phosphate dehydrogenase deficiency on benzo(a)pyrene toxicity and transforming activity for in vitro-cultured human skin fibroblasts. ( Daino, L; Feo, F; Frassetto, S; Garcea, R; Gaspa, L; Pascale, R; Pirisi, L, 1984) |
| " No differences were observed in the toxic effects of methylnitrosourea, a carcinogen that does not need metabolic activation, on normal and variant fibroblasts." | 1.26 | Effect of glucose-6-phosphate dehydrogenase deficiency on the benz(a)pyrene toxicity for in vitro cultured human skin fibroblasts. ( Daino, L; Feo, F; Frassetto, S; Garcea, R; Gaspa, L; La Spina, V; Ledda, GM; Pascale, R; Pirisi, L; Zanetti, S, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pirisi, L | 4 |
| Pascale, R | 6 |
| Daino, L | 5 |
| Frassetto, S | 4 |
| La Spina, V | 1 |
| Zanetti, S | 2 |
| Gaspa, L | 3 |
| Ledda, GM | 1 |
| Garcea, R | 5 |
| Feo, F | 6 |
| Ruggiu, ME | 3 |
| Simile, MM | 1 |
| Vannini, G | 1 |
| Seddaiu, MA | 1 |
| Satta, G | 1 |
| Lenzerini, L | 1 |
| Addis, V | 1 |
6 other studies available for benzo(a)pyrene and Glucosephosphate Dehydrogenase Deficiency
| Article | Year |
|---|---|
Effect of glucose-6-phosphate dehydrogenase deficiency on the benz(a)pyrene toxicity for in vitro cultured human skin fibroblasts.
Topics: Benzo(a)pyrene; Benzopyrenes; Cells, Cultured; Drug Resistance; Fibroblasts; Glucosephosphate Dehydr | 1982 |
Modulatory effect of glucose-6-phosphate dehydrogenase deficiency on benzo(a)pyrene toxicity and transforming activity for in vitro-cultured human skin fibroblasts.
Topics: Benzo(a)pyrene; Benzopyrenes; Biotransformation; Carcinogens; Cell Transformation, Neoplastic; Cells | 1984 |
Modulatory mechanisms of chemical carcinogenesis: the role of the NADPH pool in the benzo(a)pyrene activation.
Topics: Benzo(a)pyrene; Biotransformation; Female; Fibroblasts; Glucosephosphate Dehydrogenase Deficiency; H | 1984 |
Dependence of benzo(a)pyrene metabolism on NADPH pool in normal and glucose-6-phosphate dehydrogenase deficient human fibroblasts.
Topics: Adult; Benzo(a)pyrene; Cytochrome P-450 Enzyme System; Fibroblasts; Glucosephosphate Dehydrogenase D | 1990 |
Benzo(a)pyrene metabolism by lymphocytes from normal individuals and individuals carrying the Mediterranean variant of glucose-6-phosphate dehydrogenase.
Topics: Benzo(a)pyrene; Cells, Cultured; DNA; Glucosephosphate Dehydrogenase; Glucosephosphate Dehydrogenase | 1987 |
Control of glucose-6-phosphate dehydrogenase deficiency on the formation of mutagenic and carcinogenic metabolites derived from benzo(a)pyrene.
Topics: Benzo(a)pyrene; Biotransformation; Chromatography, High Pressure Liquid; DNA; Glucosephosphate Dehyd | 1987 |