benzo(a)pyrene has been researched along with Genome Instability in 8 studies
Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Reports of the ability of estrogenic agents such as 17beta-estradiol (E2), estriol (E3) and bisphenol A (BPA) to induce micronuclei (MN) in MCF-7 breast cancer cells have prompted us to investigate whether these effects are linked to activation of the estrogen receptor (ER) alpha." | 3.74 | Estrogens and genomic instability in human breast cancer cells--involvement of Src/Raf/Erk signaling in micronucleus formation by estrogenic chemicals. ( Kabil, A; Kortenkamp, A; Silva, E, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thaiparambil, J | 1 |
| Mansour, O | 1 |
| El-Zein, R | 1 |
| Šrut, M | 1 |
| Štambuk, A | 1 |
| Bourdineaud, JP | 1 |
| Klobučar, GI | 1 |
| Stellas, D | 1 |
| Souliotis, VL | 1 |
| Bekyrou, M | 1 |
| Smirlis, D | 1 |
| Kirsch-Volders, M | 1 |
| Degrassi, F | 1 |
| Cundari, E | 1 |
| Kyrtopoulos, SA | 1 |
| Li, X | 2 |
| Zhu, Z | 1 |
| Huang, P | 1 |
| Zhuang, Z | 1 |
| Liu, J | 1 |
| Gao, W | 1 |
| Liu, Y | 1 |
| Huang, H | 1 |
| Kabil, A | 1 |
| Silva, E | 1 |
| Kortenkamp, A | 1 |
| Klarer, AC | 1 |
| McGregor, W | 1 |
| Huang, HY | 1 |
| Cai, JF | 1 |
| Liu, QC | 1 |
| Hu, GH | 1 |
| Xia, B | 1 |
| Mao, JY | 1 |
| Wu, DS | 1 |
| Liu, JJ | 1 |
| Zhuang, ZX | 1 |
| Polyzos, A | 1 |
| Parfett, C | 1 |
| Healy, C | 1 |
| Douglas, GR | 1 |
| Yauk, CL | 1 |
1 review available for benzo(a)pyrene and Genome Instability
| Article | Year |
|---|---|
Replication of damaged genomes.
Topics: Animals; Benzo(a)pyrene; Cloning, Molecular; DNA; DNA Damage; DNA Repair; DNA Replication; DNA-Direc | 2011 |
7 other studies available for benzo(a)pyrene and Genome Instability
| Article | Year |
|---|---|
Effect of Benzo[a]Pyrene on Spindle Misorientation and Fidelity of Chromosome Segregation in Lung Epithelial BEAS-2B Cells.
Topics: Benzo(a)pyrene; Carcinogens, Environmental; Cell Line; Chromosome Segregation; DNA Damage; Epithelia | 2018 |
Zebrafish genome instability after exposure to model genotoxicants.
Topics: Amplified Fragment Length Polymorphism Analysis; Animals; Benzo(a)pyrene; Comet Assay; DNA Damage; E | 2015 |
Benzo[a]pyrene-induced cell cycle arrest in HepG2 cells is associated with delayed induction of mitotic instability.
Topics: Benzo(a)pyrene; Carcinogens, Environmental; Cell Cycle; Cell Cycle Checkpoints; DNA Adducts; DNA Dam | 2014 |
Poly(ADP-Ribose) Glycohydrolase (PARG) Silencing Suppresses Benzo(a)pyrene Induced Cell Transformation.
Topics: Animals; Benzo(a)pyrene; Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; DNA Damage; DNA R | 2016 |
Estrogens and genomic instability in human breast cancer cells--involvement of Src/Raf/Erk signaling in micronucleus formation by estrogenic chemicals.
Topics: Benzhydryl Compounds; Benzo(a)pyrene; Breast Neoplasms; Cell Line, Tumor; Estradiol; Estrogens; Extr | 2008 |
Role of poly(ADP-ribose) glycohydrolase in the regulation of cell fate in response to benzo(a)pyrene.
Topics: Apoptosis; Ataxia Telangiectasia Mutated Proteins; Benzo(a)pyrene; Cell Cycle; Cell Cycle Proteins; | 2012 |
Instability of expanded simple tandem repeats is induced in cell culture by a variety of agents: N-Nitroso-N-ethylurea, benzo(a)pyrene, etoposide and okadaic acid.
Topics: Animals; Benzo(a)pyrene; Cell Division; Cell Line; Ethylnitrosourea; Etoposide; Genomic Instability; | 2006 |