benzo(a)pyrene has been researched along with Disease Models, Animal in 101 studies
Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study examined the influence of 3,4-benzopyrene (BaP), a compound found in cigarette smoke, on the formation of angiotensin II (Ang II)-induced abdominal aortic aneurysm (AAA) formation in mice and the underlying mechanisms." | 7.80 | Exploration of the mechanisms by which 3,4-benzopyrene promotes angiotensin II-induced abdominal aortic aneurysm formation in mice. ( Guo, H; Hu, J; Ji, K; Jiang, F; Liao, L; Qian, L; Tang, J; Zhang, Y, 2014) |
| "Chrysin treatment (250mg/kg body weight) significantly attenuated all these changes thereby showing potent anti lung cancer effect." | 5.43 | Chemopreventive effect of chrysin, a dietary flavone against benzo(a)pyrene induced lung carcinogenesis in Swiss albino mice. ( Barua, CC; Bodduluru, LN; Budhani, MK; Dahiya, V; Gogoi, R; Kasala, ER; Madhana, RM; Mallugari, RR; Maramreddy, SR, 2016) |
| "Ovalbumin (OVA) and BaP co-exposure were used to establish the aggravated asthma model." | 4.84 | Qufeng Xuanbi Formula inhibited benzo[a]pyrene-induced aggravated asthma airway mucus secretion by AhR/ROS/ERK pathway. ( Hu, J; Liu, CY; Liu, L; Shi, XL; Sun, XH; Tang, LL; Wang, BH; Wang, Y; Yang, Y; Yu, KY; Zhang, Q; Zhang, XN, 2024) |
| "This study examined the influence of 3,4-benzopyrene (BaP), a compound found in cigarette smoke, on the formation of angiotensin II (Ang II)-induced abdominal aortic aneurysm (AAA) formation in mice and the underlying mechanisms." | 3.80 | Exploration of the mechanisms by which 3,4-benzopyrene promotes angiotensin II-induced abdominal aortic aneurysm formation in mice. ( Guo, H; Hu, J; Ji, K; Jiang, F; Liao, L; Qian, L; Tang, J; Zhang, Y, 2014) |
| "We evaluated deguelin and silibinin in A/J mice treated with the tobacco-specific carcinogen benzo(a)pyrene (BP) for their ability to inhibit pulmonary adenoma formation and growth." | 3.73 | Efficacy of deguelin and silibinin on benzo(a)pyrene-induced lung tumorigenesis in A/J mice. ( Lubet, RA; Tan, Q; Wang, Y; Yan, Y; You, M, 2005) |
| "Stomach cancer was induced in experimental mice using BaP oral administration." | 1.62 | Chemopreventive effect of galangin against benzo(a)pyrene-induced stomach tumorigenesis through modulating aryl hydrocarbon receptor in Swiss albino mice. ( Cheng, M; Liu, S; Wang, L; Wei, F; Xue, J; Zheng, G, 2021) |
| "lipid accumulation) and steatohepatitis have been related to diverse etiologic factors, including alcohol, obesity, environmental pollutants." | 1.48 | Co-exposure to benzo[a]pyrene and ethanol induces a pathological progression of liver steatosis in vitro and in vivo. ( Bucher, S; Chevanne, M; Coulouarn, C; Fernier, M; Fromenty, B; Gallais, I; Hamdaoui, Q; Imran, M; Lagadic-Gossmann, D; Le Guillou, D; Liamin, M; Podechard, N; Robin, MA; Sergent, O; Tête, A, 2018) |
| "Our results indicate that pulmonary inflammation increased the genotoxicity of B[a]P via inhibition of both phase I and II metabolism." | 1.46 | Altered gene expression profiles in the lungs of benzo[a]pyrene-exposed mice in the presence of lipopolysaccharide-induced pulmonary inflammation. ( Arlt, VM; Fijten, RR; Godschalk, RW; Riffo Vasquez, Y; Shi, Q; Spina, D; Van Schooten, FJ, 2017) |
| "Chrysin treatment (250mg/kg body weight) significantly attenuated all these changes thereby showing potent anti lung cancer effect." | 1.43 | Chemopreventive effect of chrysin, a dietary flavone against benzo(a)pyrene induced lung carcinogenesis in Swiss albino mice. ( Barua, CC; Bodduluru, LN; Budhani, MK; Dahiya, V; Gogoi, R; Kasala, ER; Madhana, RM; Mallugari, RR; Maramreddy, SR, 2016) |
| " The colon tumor numbers showed a B(a)P dose-response relationship." | 1.43 | Western diet enhances benzo(a)pyrene-induced colon tumorigenesis in a polyposis in rat coli (PIRC) rat model of colon cancer. ( Adunyah, SE; Amos-Landgraf, JM; Guo, Z; Harris, KL; Okoro, E; Pulliam, SR; Ramesh, A; Washington, MK, 2016) |
| "Gut microbiota dysbiosis are associated with a wide range of human diseases, including inflammatory bowel diseases." | 1.43 | Oral exposure to environmental pollutant benzo[a]pyrene impacts the intestinal epithelium and induces gut microbial shifts in murine model. ( Barnich, N; Boucher, D; Darcha, C; Déchelotte, PJ; Parisot, N; Peyret, P; Peyretaillade, E; Ribière, C, 2016) |
| "Picropodophyllin (PPP) is a potent inhibitor of IGF-1R and has antitumor efficacy in several cancer types." | 1.42 | Targeting the insulin-like growth factor-1 receptor by picropodophyllin for lung cancer chemoprevention. ( Lubet, RA; Pan, J; Wang, Y; You, M; Zhang, Q, 2015) |
| "Curcumin and quercetin treatments to mice were able to decrease significantly the levels of LPO, ROS, as well as activities of SOD, GST." | 1.42 | Protective effects of curcumin and quercetin during benzo(a)pyrene induced lung carcinogenesis in mice. ( Liu, Y; Wu, YM; Zhang, PY, 2015) |
| "Lung cancer is one of the cancers that have the highest incidence and the highest mortality rate, and it is of great interest to identify ways to prevent its occurrence." | 1.39 | Tea polyphenols prevent lung from preneoplastic lesions and effect p53 and bcl-2 gene expression in rat lung tissues. ( Chen, Q; Gu, Q; Hu, C; Xia, Y, 2013) |
| "At 47 weeks, oral squamous cell carcinomas (OSCC) were found in 31% of the high-dose B6C3F1 group." | 1.38 | Mutagenesis and carcinogenesis induced by dibenzo[a,l]pyrene in the mouse oral cavity: a potential new model for oral cancer. ( Ahn, K; Aliaga, C; Amin, S; Bruggeman, R; Chen, KM; Cooper, T; DelTondo, J; El-Bayoumy, K; Guttenplan, JB; Jiang, K; Kosinska, W; Sharma, AK; Sun, YW; Zhang, SM; Zhao, ZL, 2012) |
| "Oral formulations of 5-fluorouracil (5-FU) with enhanced bioavailability were developed using microemulsion as a drug carrier system." | 1.38 | Development and evaluation of novel microemulsion based oral formulations of 5-fluorouracil using non-everted rat intestine sac model. ( Maheshwari, M, 2012) |
| "Treatments of curcumin and resveratrol were given orally in drinking water at a dose level of 60 mg/kg body weight and 5." | 1.38 | Premature mitochondrial senescence and related ultrastructural changes during lung carcinogenesis modulation by curcumin and resveratrol. ( Dhawan, DK; Malhotra, A; Nair, P, 2012) |
| " Both S-29606 and S-30621 were dosed via nose-only inhalation 5 days a week, for 16 weeks, whereas Zileuton was administered orally." | 1.34 | Effects of novel 5-lipoxygenase inhibitors on the incidence of pulmonary adenomas in the A/J murine model when administered via nose-only inhalation. ( Angersbach, BS; Karlage, K; Kuehl, PJ; Merrill, BA; Myrdal, PB; Wightman, PD, 2007) |
| "Ischemia was induced by femoral artery occlusion in wild-type and AHR-null mice." | 1.34 | A role for the aryl hydrocarbon receptor in regulation of ischemia-induced angiogenesis. ( Gonzalez, FJ; Ichihara, G; Ichihara, S; Kondo, T; Li, P; Murohara, T; Nakajima, T; Yamada, Y, 2007) |
| "Lung cancer has emerged as one of the leading causes of cancer death in most developed and many developing countries of the world." | 1.33 | Black tea extract can modulate protein expression of H-ras, c-Myc, p53, and Bcl-2 genes during pulmonary hyperplasia, dysplasia, and carcinoma in situ. ( Banerjee, S; Das, S; Ganguly, C; Manna, S; Panda, CK; Saha, P, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (5.94) | 18.7374 |
| 1990's | 15 (14.85) | 18.2507 |
| 2000's | 32 (31.68) | 29.6817 |
| 2010's | 36 (35.64) | 24.3611 |
| 2020's | 12 (11.88) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, X | 1 |
| Guan, S | 1 |
| Sun, L | 2 |
| Dai, Z | 1 |
| Adachi, K | 1 |
| Ishizawa, M | 1 |
| Uno, S | 1 |
| Kubota, H | 1 |
| Henmi, T | 1 |
| Koshinaga, T | 1 |
| Makishima, M | 1 |
| Sakurai, K | 1 |
| Elsheikh, AM | 1 |
| M Roshdy, T | 1 |
| Hassan, SA | 1 |
| A Hussein, M | 1 |
| M Fayed, A | 1 |
| Fueldner, C | 1 |
| Riemschneider, S | 1 |
| Haupt, J | 1 |
| Jungnickel, H | 1 |
| Schulze, F | 1 |
| Zoldan, K | 1 |
| Esser, C | 1 |
| Hauschildt, S | 1 |
| Knauer, J | 1 |
| Luch, A | 1 |
| Kalkhof, S | 1 |
| Lehmann, J | 1 |
| Luo, M | 1 |
| Luo, D | 1 |
| Liu, J | 1 |
| Wang, H | 1 |
| Liu, X | 3 |
| Yang, M | 1 |
| Tian, F | 1 |
| Qin, S | 1 |
| Li, Y | 3 |
| Wang, BH | 1 |
| Tang, LL | 1 |
| Sun, XH | 1 |
| Zhang, Q | 3 |
| Liu, CY | 1 |
| Zhang, XN | 1 |
| Yu, KY | 1 |
| Yang, Y | 1 |
| Hu, J | 2 |
| Shi, XL | 1 |
| Wang, Y | 4 |
| Liu, L | 1 |
| Harris, KJ | 1 |
| Subbiah, S | 1 |
| Tabatabai, M | 1 |
| Archibong, AE | 1 |
| Singh, KP | 1 |
| Anderson, TA | 1 |
| Adunyah, SE | 4 |
| Ramesh, A | 7 |
| Tajima, H | 2 |
| Tajiki-Nishino, R | 2 |
| Watanabe, Y | 2 |
| Kurata, K | 1 |
| Fukuyama, T | 2 |
| Liu, D | 1 |
| Zhao, Y | 3 |
| Qi, Y | 1 |
| Gao, Y | 1 |
| Tu, D | 1 |
| Gao, HM | 1 |
| Zhou, H | 1 |
| Abbass, M | 1 |
| Chen, Y | 1 |
| Arlt, VM | 3 |
| Stürzenbaum, SR | 1 |
| Wang, L | 1 |
| Xue, J | 2 |
| Wei, F | 1 |
| Zheng, G | 1 |
| Cheng, M | 1 |
| Liu, S | 1 |
| Yoshikawa, Y | 1 |
| Izawa, T | 1 |
| Hamada, Y | 1 |
| Takenaga, H | 1 |
| Wang, Z | 2 |
| Ishimaru, N | 1 |
| Kamioka, H | 1 |
| Yeo, CD | 2 |
| Kim, YA | 1 |
| Lee, HY | 1 |
| Kim, JW | 2 |
| Kim, SJ | 2 |
| Lee, SH | 2 |
| Kim, YK | 2 |
| Shi, Q | 2 |
| Fijten, RR | 1 |
| Spina, D | 2 |
| Riffo Vasquez, Y | 1 |
| Godschalk, RW | 2 |
| Van Schooten, FJ | 4 |
| Li, C | 1 |
| Wang, J | 4 |
| Su, Q | 1 |
| Yang, K | 1 |
| Chen, C | 1 |
| Jiang, X | 1 |
| Han, T | 1 |
| Cheng, S | 1 |
| Mo, T | 1 |
| Zhang, R | 1 |
| Peng, B | 1 |
| Guo, Y | 1 |
| Baker, PN | 1 |
| Tu, B | 1 |
| Xia, Y | 3 |
| Bucher, S | 1 |
| Tête, A | 1 |
| Podechard, N | 1 |
| Liamin, M | 1 |
| Le Guillou, D | 1 |
| Chevanne, M | 1 |
| Coulouarn, C | 1 |
| Imran, M | 1 |
| Gallais, I | 1 |
| Fernier, M | 1 |
| Hamdaoui, Q | 1 |
| Robin, MA | 1 |
| Sergent, O | 1 |
| Fromenty, B | 1 |
| Lagadic-Gossmann, D | 1 |
| Ajayi, BO | 1 |
| Adedara, IA | 1 |
| Ajani, OS | 1 |
| Oyeyemi, MO | 1 |
| Farombi, EO | 1 |
| Huderson, AC | 1 |
| Rekha Devi, PV | 1 |
| Niaz, MS | 3 |
| Viswanathan, S | 1 |
| Berlin Grace, VM | 1 |
| Danisha, JP | 1 |
| Sun, H | 1 |
| Zhou, Y | 2 |
| Huang, K | 1 |
| Que, J | 1 |
| Peng, Y | 1 |
| Lin, C | 1 |
| Xue, Y | 1 |
| Ji, K | 2 |
| Wang, GZ | 1 |
| Zhang, L | 1 |
| Zhao, XC | 1 |
| Gao, SH | 1 |
| Qu, LW | 1 |
| Yu, H | 2 |
| Fang, WF | 1 |
| Zhou, YC | 1 |
| Liang, F | 1 |
| Zhang, C | 1 |
| Huang, YC | 1 |
| Liu, Z | 2 |
| Fu, YX | 1 |
| Zhou, GB | 1 |
| Huang, L | 1 |
| Zhang, P | 1 |
| Duan, S | 1 |
| Shao, H | 1 |
| Gao, M | 1 |
| Feng, F | 1 |
| Wang, E | 1 |
| Tu, W | 1 |
| Do, DC | 1 |
| Yang, L | 1 |
| Xu, D | 1 |
| Huang, SK | 1 |
| Yang, P | 1 |
| Ran, P | 1 |
| Gao, PS | 1 |
| Zhang, Y | 3 |
| Jiang, F | 1 |
| Qian, L | 1 |
| Guo, H | 1 |
| Liao, L | 1 |
| Tang, J | 1 |
| Iqbal, J | 1 |
| Cao, J | 1 |
| Yuen, T | 1 |
| Lu, P | 1 |
| Bab, I | 1 |
| Leu, NA | 1 |
| Srinivasan, S | 1 |
| Wagage, S | 1 |
| Hunter, CA | 1 |
| Nebert, DW | 1 |
| Zaidi, M | 1 |
| Avadhani, NG | 1 |
| Gu, Q | 2 |
| Hu, C | 2 |
| Chen, Q | 2 |
| Diggs, DL | 2 |
| Myers, JN | 1 |
| Banks, LD | 2 |
| Hood, DB | 1 |
| Roberts, LJ | 2 |
| Pan, J | 1 |
| Lubet, RA | 2 |
| You, M | 2 |
| Ha, JH | 1 |
| Kim, IK | 1 |
| Liu, Y | 1 |
| Wu, YM | 1 |
| Zhang, PY | 1 |
| Koyama, N | 1 |
| Hakura, A | 1 |
| Toritsuka, N | 1 |
| Sonoda, J | 1 |
| Seki, Y | 1 |
| Tohyama, O | 1 |
| Asakura, S | 1 |
| Nakano-Ito, K | 1 |
| Hosokawa, S | 1 |
| Haenen, GR | 1 |
| Maas, L | 1 |
| Vasquez, YR | 1 |
| Moonen, E | 1 |
| Veith, C | 1 |
| Godschalk, RWL | 1 |
| Fujioka, N | 1 |
| Fritz, V | 1 |
| Upadhyaya, P | 1 |
| Kassie, F | 1 |
| Hecht, SS | 1 |
| Amoah, P | 1 |
| Washington, MK | 2 |
| Kasala, ER | 1 |
| Bodduluru, LN | 1 |
| Barua, CC | 1 |
| Madhana, RM | 1 |
| Dahiya, V | 1 |
| Budhani, MK | 1 |
| Mallugari, RR | 1 |
| Maramreddy, SR | 1 |
| Gogoi, R | 1 |
| Harris, KL | 2 |
| Pulliam, SR | 1 |
| Okoro, E | 1 |
| Guo, Z | 2 |
| Amos-Landgraf, JM | 1 |
| Ribière, C | 1 |
| Peyret, P | 1 |
| Parisot, N | 1 |
| Darcha, C | 1 |
| Déchelotte, PJ | 1 |
| Barnich, N | 1 |
| Peyretaillade, E | 1 |
| Boucher, D | 1 |
| Zhao, Q | 1 |
| Sharma, V | 1 |
| Nguyen, LP | 1 |
| Lee, YN | 1 |
| Pham, KL | 1 |
| Edderkaoui, M | 1 |
| Pandol, SJ | 1 |
| Park, W | 1 |
| Habtezion, A | 1 |
| Gangar, SC | 1 |
| Koul, A | 2 |
| Ramos, KS | 1 |
| Tanwar, L | 1 |
| Arora, N | 1 |
| Yang, H | 2 |
| Zhou, L | 1 |
| Lin, X | 1 |
| Feng, J | 1 |
| Arafa, HM | 1 |
| Aly, HA | 1 |
| Abd-Ellah, MF | 1 |
| El-Refaey, HM | 1 |
| Brandon, JL | 1 |
| Conti, CJ | 1 |
| Goldstein, LS | 2 |
| DiGiovanni, J | 2 |
| Gimenez-Conti, IB | 1 |
| Chevillard, G | 1 |
| Paquet, M | 1 |
| Blank, V | 1 |
| Kung, MH | 1 |
| Yukata, K | 1 |
| O'Keefe, RJ | 1 |
| Zuscik, MJ | 1 |
| Chen, Z | 1 |
| Yang, J | 1 |
| Jin, M | 1 |
| Wang, XW | 1 |
| Shen, ZQ | 1 |
| Qiu, Z | 1 |
| Zhao, G | 1 |
| Li, JW | 1 |
| Guttenplan, JB | 1 |
| Kosinska, W | 1 |
| Zhao, ZL | 1 |
| Chen, KM | 1 |
| Aliaga, C | 1 |
| DelTondo, J | 1 |
| Cooper, T | 1 |
| Sun, YW | 1 |
| Zhang, SM | 1 |
| Jiang, K | 1 |
| Bruggeman, R | 1 |
| Sharma, AK | 1 |
| Amin, S | 1 |
| Ahn, K | 1 |
| El-Bayoumy, K | 1 |
| Maheshwari, M | 1 |
| Bassi, DE | 1 |
| Klein-Szanto, AJ | 1 |
| Chandrashekar, N | 1 |
| Selvamani, A | 1 |
| Subramanian, R | 1 |
| Pandi, A | 1 |
| Thiruvengadam, D | 1 |
| Rekhadevi, PV | 1 |
| Malhotra, A | 2 |
| Nair, P | 2 |
| Dhawan, DK | 2 |
| Tchou-Wong, KM | 2 |
| Jiang, Y | 1 |
| Yee, H | 1 |
| LaRosa, J | 1 |
| Lee, TC | 1 |
| Pellicer, A | 1 |
| Jagirdar, J | 1 |
| Gordon, T | 1 |
| Goldberg, JD | 1 |
| Rom, WN | 2 |
| Rajeswari, MR | 1 |
| Jain, A | 1 |
| Sharma, A | 1 |
| Singh, D | 1 |
| Jagannathan, NR | 1 |
| Sharma, U | 1 |
| Degaonkar, MN | 1 |
| Degonkar, MN | 1 |
| Curfs, DM | 1 |
| Beckers, L | 1 |
| Gijbels, MJ | 1 |
| Godschalk, R | 1 |
| Curfs, D | 1 |
| Bartsch, H | 1 |
| Nair, J | 1 |
| Selvendiran, K | 2 |
| Senthilnathan, P | 2 |
| Magesh, V | 1 |
| Sakthisekaran, D | 3 |
| Dasgupta, T | 1 |
| Banerjee, S | 2 |
| Yadava, PK | 1 |
| Rao, AR | 2 |
| Banu, SM | 2 |
| Inyang, F | 1 |
| Knuckles, ME | 1 |
| Rowe, CA | 1 |
| Nantz, MP | 1 |
| Deniera, C | 1 |
| Green, K | 1 |
| Talcott, ST | 1 |
| Percival, SS | 1 |
| Saha, P | 1 |
| Ganguly, C | 1 |
| Manna, S | 1 |
| Panda, CK | 1 |
| Das, S | 1 |
| Yan, Y | 1 |
| Tan, Q | 1 |
| Padmavathi, R | 1 |
| Umemura, T | 1 |
| Kodama, Y | 1 |
| Nishikawa, A | 1 |
| Hioki, K | 1 |
| Nomura, T | 1 |
| Kanki, K | 1 |
| Kuroiwa, Y | 1 |
| Ishii, Y | 1 |
| Kurokawa, Y | 1 |
| Hirose, M | 1 |
| Deep, G | 1 |
| Dhiman, M | 1 |
| Kale, RK | 1 |
| Myrdal, PB | 1 |
| Karlage, K | 1 |
| Kuehl, PJ | 1 |
| Angersbach, BS | 1 |
| Merrill, BA | 1 |
| Wightman, PD | 1 |
| Ichihara, S | 1 |
| Yamada, Y | 1 |
| Ichihara, G | 1 |
| Nakajima, T | 1 |
| Li, P | 1 |
| Kondo, T | 1 |
| Gonzalez, FJ | 1 |
| Murohara, T | 1 |
| Benfield, JR | 3 |
| Shors, EC | 2 |
| Hammond, WG | 3 |
| Paladugu, RR | 1 |
| Cohen, AH | 1 |
| Jensen, T | 1 |
| Fu, PC | 1 |
| Pak, HY | 2 |
| Teplitz, RL | 2 |
| Neumann, OG | 1 |
| Kmoch, N | 1 |
| Ketkar, M | 1 |
| Paladugu, R | 1 |
| Luo, S | 1 |
| Wang, C | 1 |
| Zhu, H | 1 |
| Trush, MA | 1 |
| Schaeffer, DJ | 1 |
| Wolterbeek, AP | 1 |
| Schoevers, EJ | 1 |
| Rutten, AA | 1 |
| Feron, VJ | 1 |
| Heinrich, U | 1 |
| Roller, M | 1 |
| Pott, F | 1 |
| Dragan, YP | 1 |
| Laufer, C | 1 |
| Koleske, AJ | 1 |
| Drinkwater, N | 1 |
| Pitot, HC | 1 |
| Varga, C | 1 |
| Horváth, G | 1 |
| Timbrell, V | 1 |
| Badary, OA | 1 |
| Al-Shabanah, OA | 1 |
| Nagi, MN | 1 |
| Al-Rikabi, AC | 1 |
| Elmazar, MM | 1 |
| Silva, RA | 1 |
| Muñoz, SE | 1 |
| Perez, CA | 1 |
| Eynard, AR | 1 |
| Ramos-Gomez, M | 1 |
| Kwak, MK | 1 |
| Dolan, PM | 1 |
| Itoh, K | 1 |
| Yamamoto, M | 1 |
| Talalay, P | 1 |
| Kensler, TW | 1 |
| Chen, XG | 1 |
| Yan, CH | 1 |
| Li, LN | 1 |
| Han, R | 1 |
| de Boer, JG | 1 |
| Wu, K | 1 |
| Shan, YJ | 1 |
| Yu, JW | 1 |
| Liu, BH | 1 |
| Cavin, C | 1 |
| Holzhaeuser, D | 1 |
| Scharf, G | 1 |
| Constable, A | 1 |
| Huber, WW | 1 |
| Schilter, B | 1 |
| Faiderbe, S | 1 |
| Chagnaud, JL | 1 |
| De Seze, R | 1 |
| Geffard, M | 1 |
| Aruna, K | 1 |
| Sivaramakrishnan, VM | 1 |
| Shandala, MG | 1 |
| Ianysheva, NIa | 3 |
| Balenko, NV | 2 |
| Chernichenko, IA | 3 |
| Babiĭ, VF | 2 |
| Bakanova, GN | 1 |
| Lemeshko, LP | 1 |
| Grigor'eva, LV | 1 |
| Vinogradov, GI | 1 |
| Kroes, R | 1 |
| Beems, RB | 1 |
| Bosland, MC | 1 |
| Bunnik, GS | 1 |
| Sinkeldam, EJ | 1 |
| Matsumoto, RM | 1 |
| Jusko, WJ | 1 |
| Corcoran, GB | 1 |
| Nesnow, S | 1 |
| Bergman, H | 1 |
| Slaga, TJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized, Double-Blinded, Placebo-Controlled Study With Immunotype Specific Dietary Supplements to Improve Inflammatory Age® by Edifice Health[NCT04983017] | 750 participants (Anticipated) | Interventional | 2021-08-10 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for benzo(a)pyrene and Disease Models, Animal
| Article | Year |
|---|---|
Research on cruciferous vegetables, indole-3-carbinol, and cancer prevention: A tribute to Lee W. Wattenberg.
Topics: Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Biomarkers; Brassicaceae; Carcinogens; Cell Line, | 2016 |
Planarians as a model system for in vivo tumorigenesis studies.
Topics: Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Cadmium; Carcinogenicity Tests; Disease Models, Animal; | 1993 |
A critical appraisal of intratracheal instillation of benzo[a]pyrene to Syrian golden hamsters as a model in respiratory tract carcinogenesis.
Topics: Animals; Benzo(a)pyrene; Cricetinae; Disease Models, Animal; Female; Ferric Compounds; Instillation, | 1995 |
Protection by dietary compounds against mutation in a transgenic rodent.
Topics: Aflatoxin B1; Animals; Animals, Genetically Modified; Bacterial Proteins; Benzo(a)pyrene; Carcinogen | 2001 |
Cafestol and kahweol, two coffee specific diterpenes with anticarcinogenic activity.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Ce | 2002 |
Modification of multistage skin carcinogenesis in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Cocarcinogenesis; Disease Models, Animal; | 1991 |
Nutritional factors in lung, colon, and prostate carcinogenesis in animal models.
Topics: 1,2-Dimethylhydrazine; Androgens; Animals; Benzo(a)pyrene; Colonic Neoplasms; Diet; Dietary Fats; Di | 1986 |
94 other studies available for benzo(a)pyrene and Disease Models, Animal
| Article | Year |
|---|---|
The impact of benzo[a]pyrene on murine allergic airway inflammation via epigenetic remodeling.
Topics: Airway Remodeling; Animals; Asthma; Benzo(a)pyrene; Disease Models, Animal; DNA Methylation; Epigene | 2022 |
Oral benzo[a]pyrene administration attenuates dextran sulfate sodium-induced colitis in mice.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Benzo(a)pyrene; Colitis; Dextran Sulfate; D | 2022 |
Resveratrol: A Potential Protector Against Benzo[a]pyrene- Induced Lung Toxicity.
Topics: Animals; Antioxidants; Benzo(a)pyrene; Disease Models, Animal; Egypt; Lung; Oxidative Stress; Protec | 2022 |
Aryl Hydrocarbon Receptor Activation by Benzo[
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Benzo(a)pyrene; Disease Models, Animal; Mice; | 2022 |
Ameliorative effect of the probiotic peptide against benzo(α)pyrene-induced inflammatory damages in enterocytes.
Topics: Animals; Benzo(a)pyrene; Caco-2 Cells; Cytokines; Disease Models, Animal; Enterocytes; Heme Oxygenas | 2022 |
Qufeng Xuanbi Formula inhibited benzo[a]pyrene-induced aggravated asthma airway mucus secretion by AhR/ROS/ERK pathway.
Topics: Air Pollutants; Animals; Asthma; Benzo(a)pyrene; Disease Models, Animal; Extracellular Signal-Regula | 2024 |
Pressurized liquid extraction followed by liquid chromatography coupled to a fluorescence detector and atmospheric pressure chemical ionization mass spectrometry for the determination of benzo(a)pyrene metabolites in liver tissue of an animal model of col
Topics: Animals; Atmospheric Pressure; Benzo(a)pyrene; Chromatography, Liquid; Colonic Neoplasms; Disease Mo | 2020 |
Activation of aryl hydrocarbon receptor by benzo[a]pyrene increases interleukin 33 expression and eosinophil infiltration in a mouse model of allergic airway inflammation.
Topics: A549 Cells; Animals; Basic Helix-Loop-Helix Transcription Factors; Benzo(a)pyrene; Chemotaxis, Leuko | 2020 |
Benzo(a)pyrene exposure induced neuronal loss, plaque deposition, and cognitive decline in APP/PS1 mice.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Behavior, Animal; Benzo(a)pyrene; Cognit | 2020 |
Benzo[a]pyrene and Caenorhabditis elegans: defining the genotoxic potential in an organism lacking the classical CYP1A1 pathway.
Topics: Animals; Benzo(a)pyrene; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Comet Assay; Cytoc | 2021 |
Chemopreventive effect of galangin against benzo(a)pyrene-induced stomach tumorigenesis through modulating aryl hydrocarbon receptor in Swiss albino mice.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Benzo(a)pyrene; Carcinogenesis; Cell Transfor | 2021 |
Roles for B[a]P and FICZ in subchondral bone metabolism and experimental temporomandibular joint osteoarthritis via the AhR/Cyp1a1 signaling axis.
Topics: Animals; Benzo(a)pyrene; Bone Resorption; Carbazoles; Cytochrome P-450 CYP1A1; Disease Models, Anima | 2021 |
Roflumilast treatment inhibits lung carcinogenesis in benzo(a)pyrene-induced murine lung cancer model.
Topics: Aminopyridines; Animals; Benzamides; Benzo(a)pyrene; Biomarkers, Tumor; Carcinogenesis; Cell Line, T | 2017 |
Altered gene expression profiles in the lungs of benzo[a]pyrene-exposed mice in the presence of lipopolysaccharide-induced pulmonary inflammation.
Topics: Animals; Benzo(a)pyrene; Disease Models, Animal; DNA Adducts; Gene Expression Profiling; Gene Regula | 2017 |
Postnatal Subacute Benzo(a)Pyrene Exposure Caused Neurobehavioral Impairment and Metabolomic Changes of Cerebellum in the Early Adulthood Period of Sprague-Dawley Rats.
Topics: Animals; Animals, Newborn; Benzo(a)pyrene; Cerebellum; Disease Models, Animal; Exploratory Behavior; | 2018 |
Co-exposure to benzo[a]pyrene and ethanol induces a pathological progression of liver steatosis in vitro and in vivo.
Topics: Animals; Benzo(a)pyrene; Biomarkers; Cell Line; Disease Models, Animal; Disease Progression; Environ | 2018 |
[6]-Gingerol modulates spermatotoxicity associated with ulcerative colitis and benzo[a]pyrene exposure in BALB/c mice.
Topics: Animals; Benzo(a)pyrene; Catechols; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Fa | 2018 |
Alteration of benzo(a)pyrene biotransformation by resveratrol in Apc
Topics: Animals; Antioxidants; Apoptosis; Benzo(a)pyrene; Biotransformation; Carcinogenesis; Carcinogens, En | 2019 |
Enhancement of tumor suppressor RAR-β protein expression by cationic liposomal-ATRA treatment in benzo(a)pyrene-induced lung cancer mice model.
Topics: Animals; Antineoplastic Agents; Benzo(a)pyrene; Cholesterol; Disease Models, Animal; Fatty Acids, Mo | 2019 |
Circular RNA microarray expression profile in 3,4-benzopyrene/angiotensin II-induced abdominal aortic aneurysm in mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Benzo(a)pyrene; Disease Models, Animal; Gene On | 2019 |
Direct activation of aryl hydrocarbon receptor by benzo[a]pyrene elicits T-helper 2-driven proinflammatory responses in a mouse model of allergic dermatitis.
Topics: Animals; Benzo(a)pyrene; Cell Proliferation; Cells, Cultured; Cytokines; Dendritic Cells; Dermatitis | 2019 |
The Aryl hydrocarbon receptor mediates tobacco-induced PD-L1 expression and is associated with response to immunotherapy.
Topics: Animals; Antibodies, Monoclonal; B7-H1 Antigen; Benzo(a)pyrene; Benzoflavones; Carcinogens; Cell Lin | 2019 |
The comparison of two mouse models of inflammation-related lung tumorigenesis induced by benzo(a)pyrene and lipopolysaccharide.
Topics: Animals; Benzo(a)pyrene; Carcinogenesis; Carcinogens; Disease Models, Animal; Female; Inflammation; | 2019 |
Benzo(a)pyrene facilitates dermatophagoides group 1 (Der f 1)-induced epithelial cytokine release through aryl hydrocarbon receptor in asthma.
Topics: Allergens; Animals; Antigens, Dermatophagoides; Arthropod Proteins; Asthma; Benzo(a)pyrene; Cysteine | 2019 |
Exploration of the mechanisms by which 3,4-benzopyrene promotes angiotensin II-induced abdominal aortic aneurysm formation in mice.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apoptosis; Benzo(a)pyrene; Di | 2014 |
Smoke carcinogens cause bone loss through the aryl hydrocarbon receptor and induction of Cyp1 enzymes.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Bone Resorption; Carcinogens; Cytochrome P-4 | 2013 |
Tea polyphenols prevent lung from preneoplastic lesions and effect p53 and bcl-2 gene expression in rat lung tissues.
Topics: Animals; Benzo(a)pyrene; Carcinogens; Disease Models, Animal; Lung; Lung Neoplasms; Male; Polyphenol | 2013 |
Influence of dietary fat type on benzo(a)pyrene [B(a)P] biotransformation in a B(a)P-induced mouse model of colon cancer.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Biotransformation; Carcinogens; Chromatograp | 2013 |
Targeting the insulin-like growth factor-1 receptor by picropodophyllin for lung cancer chemoprevention.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Benzo(a)pyrene; Carcinogens; Cell Line, Tumor; Cell Pro | 2015 |
Chemopreventive effect of phosphodieasterase-4 inhibition in benzo(a)pyrene-induced murine lung cancer model.
Topics: Animals; Benzo(a)pyrene; Cadherins; Carcinogenesis; Chemoprevention; Disease Models, Animal; Female; | 2014 |
Protective effects of curcumin and quercetin during benzo(a)pyrene induced lung carcinogenesis in mice.
Topics: Animals; Antioxidants; Benzo(a)pyrene; Curcumin; Disease Models, Animal; Lung; Lung Neoplasms; Male; | 2015 |
Wif1 and Ifitm3 gene expression preferentially altered in the colon mucosa of benzo[a]pyrene pre-treated mice following exposure to dextran sulfate sodium.
Topics: Adaptor Proteins, Signal Transducing; Animals; Benzo(a)pyrene; Colitis; Colonic Neoplasms; Dextran S | 2015 |
Inflammation-associated extracellular β-glucuronidase alters cellular responses to the chemical carcinogen benzo[a]pyrene.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Benzo(a)pyrene; Biotransformation; Carcinogen | 2016 |
Olive oil prevents benzo(a)pyrene [B(a)P]-induced colon carcinogenesis through altered B(a)P metabolism and decreased oxidative damage in Apc(Min) mouse model.
Topics: Animals; Benzo(a)pyrene; Carcinogens; Colonic Neoplasms; Disease Models, Animal; Genes, APC; Mice; O | 2016 |
Chemopreventive effect of chrysin, a dietary flavone against benzo(a)pyrene induced lung carcinogenesis in Swiss albino mice.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Ascorbic Acid; Benzo(a)pyrene; Carcinogenesis; Catal | 2016 |
Western diet enhances benzo(a)pyrene-induced colon tumorigenesis in a polyposis in rat coli (PIRC) rat model of colon cancer.
Topics: Animals; Benzo(a)pyrene; Carcinogens; Colonic Neoplasms; Diet, Western; Disease Models, Animal; Male | 2016 |
Oral exposure to environmental pollutant benzo[a]pyrene impacts the intestinal epithelium and induces gut microbial shifts in murine model.
Topics: Administration, Oral; Animals; Benzo(a)pyrene; Disease Models, Animal; Dysbiosis; Environmental Expo | 2016 |
Aryl Hydrocarbon Receptor Ligands in Cigarette Smoke Induce Production of Interleukin-22 to Promote Pancreatic Fibrosis in Models of Chronic Pancreatitis.
Topics: Actins; Animals; Antibodies; Benzo(a)pyrene; CD4-Positive T-Lymphocytes; Cells, Cultured; Ceruletide | 2016 |
Histochemical, ultrastructural, and biochemical evidences for Azadirachta indica-induced apoptosis in benzo(a)pyrene-induced murine forestomach tumors.
Topics: Animals; Antineoplastic Agents; Apoptosis; Azadirachta; Benzo(a)pyrene; Carcinogens; Cardia; Disease | 2008 |
The development of abdominal aortic aneurysms in mice is enhanced by benzo(a)pyrene.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Aortic Rupture; Benzo(a)pyrene; Disease | 2008 |
Celecoxib administration exhibits tissue specific effect on 3H-benzo(a)pyrene-DNA adduct formation in cigarette smoke inhaling mice.
Topics: Administration, Oral; Animals; Benzo(a)pyrene; Body Weight; Celecoxib; Cytochrome P-450 Enzyme Syste | 2009 |
Overexpression of antioxidant enzymes in ApoE-deficient mice suppresses benzo(a)pyrene-accelerated atherosclerosis.
Topics: Animals; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Benzo(a)pyrene; Catalase; Cell Adhesio | 2009 |
Development of a rat model by 3,4-benzopyrene intra-pulmonary injection and evaluation of the effect of green tea drinking on p53 and bcl-2 expression in lung carcinoma.
Topics: Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carcinoma; Chemoprevention; Disease Models, Animal | 2009 |
Hesperidin attenuates benzo[alpha] pyrene-induced testicular toxicity in rats via regulation of oxidant/antioxidant balance.
Topics: Animals; Antioxidants; Benzo(a)pyrene; Carcinogens; Disease Models, Animal; Glutathione; Glutathione | 2009 |
Carcinogenic effects of MGP-7 and B[a]P on the hamster cheek pouch.
Topics: Animals; Benzo(a)pyrene; Carcinogenicity Tests; Carcinoma, Squamous Cell; Cell Proliferation; Cheek; | 2009 |
Nfe2l3 (Nrf3) deficiency predisposes mice to T-cell lymphoblastic lymphoma.
Topics: Animals; Basic-Leucine Zipper Transcription Factors; Benzo(a)pyrene; Disease Models, Animal; Disease | 2011 |
Aryl hydrocarbon receptor-mediated impairment of chondrogenesis and fracture healing by cigarette smoke and benzo(a)pyrene.
Topics: Animals; Benzo(a)pyrene; Cell Survival; Chondrocytes; Chondrogenesis; Disease Models, Animal; Femora | 2012 |
Estrogen promotes benzo[a]pyrene-induced lung carcinogenesis through oxidative stress damage and cytochrome c-mediated caspase-3 activation pathways in female mice.
Topics: Animals; Benzo(a)pyrene; Caspase 3; Cytochromes c; Disease Models, Animal; DNA Damage; Drug Synergis | 2011 |
Mutagenesis and carcinogenesis induced by dibenzo[a,l]pyrene in the mouse oral cavity: a potential new model for oral cancer.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogenicity Tests; Carcinogens; Carcinoma, Squamous Cell; | 2012 |
Development and evaluation of novel microemulsion based oral formulations of 5-fluorouracil using non-everted rat intestine sac model.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Benzo(a)pyrene; Biological Availabil | 2012 |
Carcinogen-induced animal models of head and neck squamous cell carcinoma.
Topics: Animals; Benzo(a)pyrene; Carcinoma, Squamous Cell; Cricetinae; Disease Models, Animal; Female; Head | 2007 |
Baicalein inhibits pulmonary carcinogenesis-associated inflammation and interferes with COX-2, MMP-2 and MMP-9 expressions in-vivo.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Benzo(a)pyrene; Cyclooxygenase 2; Cytokines; Diseas | 2012 |
Tumor microsomal metabolism of the food toxicant, benzo(a)pyrene, in ApcMin mouse model of colon cancer.
Topics: Adenomatous Polyposis Coli Protein; Analysis of Variance; Animals; Benzo(a)pyrene; Biotransformation | 2012 |
Curcumin and resveratrol in combination modulates benzo(a)pyrene-induced genotoxicity during lung carcinogenesis.
Topics: Animals; Antimutagenic Agents; Apoptosis; Benzo(a)pyrene; Carcinogens; Curcumin; Disease Models, Ani | 2012 |
Premature mitochondrial senescence and related ultrastructural changes during lung carcinogenesis modulation by curcumin and resveratrol.
Topics: Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carcinogens; Cellular Senescence; Curcumin; Diseas | 2012 |
Lung-specific expression of dominant-negative mutant p53 in transgenic mice increases spontaneous and benzo(a)pyrene-induced lung cancer.
Topics: Adenocarcinoma; Animals; Benzo(a)pyrene; Carcinogens; Disease Models, Animal; GADD45 Proteins; Genes | 2002 |
Lung-specific expression of mutant p53 as mouse model for lung cancer.
Topics: Adenocarcinoma; Animals; Benzo(a)pyrene; Carcinogens; Disease Models, Animal; Genes, p53; Humans; In | 2003 |
Evaluation of skin tumors by magnetic resonance imaging.
Topics: Animals; Benzo(a)pyrene; Carcinogens; Carcinoma, Squamous Cell; Disease Models, Animal; Female; Magn | 2003 |
Modulation of plasma lipid levels affects benzo[a]pyrene-induced DNA damage in tissues of two hyperlipidemic mouse models.
Topics: Animals; Apolipoprotein E3; Apolipoproteins E; Benzo(a)pyrene; Carcinogens; Disease Models, Animal; | 2003 |
Benzo[a]pyrene enhances lipid peroxidation induced DNA damage in aorta of apolipoprotein E knockout mice.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Aorta; Apolipoproteins E; Benzo(a)pyren | 2003 |
Modulatory effect of Piperine on mitochondrial antioxidant system in Benzo(a)pyrene-induced experimental lung carcinogenesis.
Topics: Alkaloids; Animals; Antineoplastic Agents; Antioxidants; Benzo(a)pyrene; Benzodioxoles; Disease Mode | 2004 |
Chemopreventive potential of Azadirachta indica (Neem) leaf extract in murine carcinogenesis model systems.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Anticarcinogenic Agents; Antioxidan | 2004 |
Protective effect of piperine on benzo(a)pyrene-induced lung carcinogenesis in Swiss albino mice.
Topics: Animals; Antioxidants; Benzo(a)pyrene; Cell Division; Disease Models, Animal; Lipid Peroxidation; Lu | 2004 |
Modulation of adult rat benzo(a)pyrene (BaP) metabolism and DNA adduct formation by neonatal diethylstilbestrol (DES) exposure.
Topics: Animals; Animals, Newborn; Benzo(a)pyrene; Carcinogens; Chromatography, High Pressure Liquid; Diethy | 2004 |
Inhibition of neoplastic transformation of benzo[alpha]pyrene-treated BALB/c 3T3 murine cells by a phytochemical extract of passionfruit juice.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Apoptosis; Benzo(a)pyrene; Caspase 3; Caspases; Cell Divi | 2004 |
Black tea extract can modulate protein expression of H-ras, c-Myc, p53, and Bcl-2 genes during pulmonary hyperplasia, dysplasia, and carcinoma in situ.
Topics: Animals; Animals, Newborn; Anticarcinogenic Agents; Apoptosis; Benzo(a)pyrene; Biflavonoids; Carcino | 2005 |
Efficacy of deguelin and silibinin on benzo(a)pyrene-induced lung tumorigenesis in A/J mice.
Topics: Adenoma; Administration, Oral; Animals; Benzo(a)pyrene; Disease Models, Animal; Lung Neoplasms; Mice | 2005 |
Enhancement of antitumor effect of paclitaxel in combination with immunomodulatory Withania somnifera on benzo(a)pyrene induced experimental lung cancer.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzo(a)pyrene; Dise | 2006 |
Nine-week detection of six genotoxic lung carcinogens using the rasH2/BHT mouse model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkylating Agents; Animals; Antioxidants; Benzo(a)pyrene; Butylate | 2006 |
Chemopreventive potential of Triphala (a composite Indian drug) on benzo(a)pyrene induced forestomach tumorigenesis in murine tumor model system.
Topics: Animals; Antioxidants; Benzo(a)pyrene; Disease Models, Animal; Dose-Response Relationship, Drug; Lip | 2005 |
Effects of novel 5-lipoxygenase inhibitors on the incidence of pulmonary adenomas in the A/J murine model when administered via nose-only inhalation.
Topics: Adenoma; Administration, Inhalation; Administration, Oral; Animals; Benzo(a)pyrene; Disease Models, | 2007 |
A role for the aryl hydrocarbon receptor in regulation of ischemia-induced angiogenesis.
Topics: Angiogenic Proteins; Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; Basic Helix-Loop-Helix | 2007 |
A clinically relevant canine lung cancer model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Delayed-Action | 1981 |
[Benzopyrene (BaP) implants into the glottic mucous membrane of hamsters].
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Cricetinae; Disease Models, Animal; Drug Implants; Epithelium | 1983 |
A family of epidermoid lung cancer models.
Topics: Animals; Benzo(a)pyrene; Bronchial Neoplasms; Carcinoma, Squamous Cell; Cell Transformation, Neoplas | 1984 |
[Co-carcinogenic effect of crocidolite plus benzo(a)pyrene on the lungs of rats].
Topics: Animals; Asbestos, Crocidolite; Benzo(a)pyrene; Carcinogens; Cocarcinogenesis; Disease Models, Anima | 1995 |
Characterization of benzo[a]pyrene quinone-induced toxicity to primary cultured bone marrow stromal cells from DBA/2 mice: potential role of mitochondrial dysfunction.
Topics: Adenosine Triphosphate; Anemia, Aplastic; Animals; Antimetabolites, Antineoplastic; Antineoplastic A | 1995 |
Estimation of a lifetime unit lung cancer risk for benzo(a)pyrene based on tumour rates in rats exposed to coal tar/pitch condensation aerosol.
Topics: Administration, Inhalation; Aerosols; Animals; Benzo(a)pyrene; Coal Tar; Disease Models, Animal; Dos | 1994 |
Quantitative comparison of initiation and mutation phenotypes in hepatocytes of the analbuminemic rat.
Topics: Albumins; Animals; Benzo(a)pyrene; Cocarcinogenesis; Disease Models, Animal; Female; Glutathione Tra | 1993 |
On the mechanism of cogenotoxic action between ingested amphibole asbestos fibres and benzo[a]pyrene: II. Tissue specificity studies using comet assay.
Topics: Animals; Asbestos, Amphibole; Benzo(a)pyrene; Carcinogens; Cocarcinogenesis; Disease Models, Animal; | 1999 |
Inhibition of benzo(a)pyrene-induced forestomach carcinogenesis in mice by thymoquinone.
Topics: Analysis of Variance; Animals; Antineoplastic Agents; Benzo(a)pyrene; Benzoquinones; Carcinoma, Squa | 1999 |
Effects of dietary fat on benz-a-pyrene-induced forestomach tumorigenesis in mice chronically exposed to arsenic.
Topics: Animals; Arsenic; Benzo(a)pyrene; Carcinogens; Dietary Fats; Disease Models, Animal; Drug Interactio | 2000 |
Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice.
Topics: Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carcinogenicity Tests; Carcinogens; Cell Nucleus; | 2001 |
Cancer chemopreventive activities of S-3-1, a synthetic derivative of danshinone.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Benzofurans; Bep | 2001 |
To BaP or not to BaP? That is the question.
Topics: Administration, Inhalation; Administration, Oral; Administration, Topical; Animals; Benzo(a)pyrene; | 2001 |
Inhibitory effects of RRR-alpha-tocopheryl succinate on benzo(a)pyrene (B(a)P)-induced forestomach carcinogenesis in female mice.
Topics: Animals; Antineoplastic Agents; Benzo(a)pyrene; Carcinogenicity Tests; Disease Models, Animal; Femal | 2001 |
Curative effects of all-trans-retinoic acid on rat sarcomas.
Topics: Animals; Anticarcinogenic Agents; Autoantibodies; Benzo(a)pyrene; Cell Division; Disease Models, Ani | 1992 |
Anticarcinogenic effects of some Indian plant products.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Body Weight; Carcinoma, Squamous C | 1992 |
Bronchial and pulmonary carcinogenesis at focal sites in dogs and hamsters.
Topics: Animals; Benzo(a)pyrene; Bronchial Neoplasms; Bronchoscopy; Carcinogens; Cricetinae; Disease Models, | 1992 |
[The role of toxic modifying substances in chemical carcinogenesis].
Topics: Animals; Benzo(a)pyrene; Cocarcinogenesis; Disease Models, Animal; Dose-Response Relationship, Drug; | 1991 |
[Experimental study of combined effects of benzo(a)pyrene and ortho-cresol on the body].
Topics: Animals; Benzo(a)pyrene; Cocarcinogenesis; Cresols; Disease Models, Animal; Dose-Response Relationsh | 1990 |
[Modeling of the interactions of biological and chemical environmental factors in experimental animals].
Topics: Animals; Benzo(a)pyrene; Carbon Disulfide; Disease Models, Animal; Drug Synergism; Escherichia coli; | 1990 |
Hepatic cytochrome P-450 and in vitro drug metabolism in an overfed rat model of obesity.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Cytochrome P-450 Enzyme System; Disease Mode | 1988 |
Comparison of the tumorigenic response of SENCAR and C57BL/6 mice to benzo(a)pyrene and the inter-experimental variability over a three-year period.
Topics: Animals; Benzo(a)pyrene; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Male; Mice; M | 1986 |