benzo(a)pyrene has been researched along with Disease Exacerbation in 18 studies
Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have shown previously that naturally occurring isothiocyanates derived from cruciferous vegetables and their N-acetylcysteine conjugates inhibit lung adenoma formation induced by tobacco carcinogens in A/J mice at the post-initiation stage." | 7.73 | Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice. ( Chung, FL; Conaway, CC; Hecht, SS; McIntee, EJ; Pittman, B; Schwartz, JE; Tian, D; Wang, CX; Yang, YM, 2005) |
| "We have shown previously that naturally occurring isothiocyanates derived from cruciferous vegetables and their N-acetylcysteine conjugates inhibit lung adenoma formation induced by tobacco carcinogens in A/J mice at the post-initiation stage." | 3.73 | Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice. ( Chung, FL; Conaway, CC; Hecht, SS; McIntee, EJ; Pittman, B; Schwartz, JE; Tian, D; Wang, CX; Yang, YM, 2005) |
| "lipid accumulation) and steatohepatitis have been related to diverse etiologic factors, including alcohol, obesity, environmental pollutants." | 1.48 | Co-exposure to benzo[a]pyrene and ethanol induces a pathological progression of liver steatosis in vitro and in vivo. ( Bucher, S; Chevanne, M; Coulouarn, C; Fernier, M; Fromenty, B; Gallais, I; Hamdaoui, Q; Imran, M; Lagadic-Gossmann, D; Le Guillou, D; Liamin, M; Podechard, N; Robin, MA; Sergent, O; Tête, A, 2018) |
| "Using skin cancer model, we demonstrated that high levels of HMGB directly correlate with the extent of neoplastic changes, and it appears that HMGB is an effective stimulus for cell differentiation, tumor progression, and metastatic invasion." | 1.35 | Overexpression of high mobility group (HMG) B1 and B2 proteins directly correlates with the progression of squamous cell carcinoma in skin. ( Rajeswari, MR; Ray, R; Sharma, A, 2008) |
| "With the onset of metastasis, HABP1 overexpression was confined to metastatic islands, while it disappeared gradually from the surrounding mass." | 1.32 | Differential expression of Hyaluronic Acid Binding Protein 1 (HABP1)/P32/C1QBP during progression of epidermal carcinoma. ( Chowdhury, AR; Datta, K; Ghosh, I; Rajeswari, MR, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 8 (44.44) | 29.6817 |
| 2010's | 8 (44.44) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Farombi, EO | 1 |
| Ajayi, BO | 1 |
| Adedara, IA | 1 |
| Chen, L | 1 |
| Bao, BY | 1 |
| Chang, WC | 1 |
| Ho, JY | 1 |
| Cheng, BH | 1 |
| Wang, CL | 1 |
| Tang, Q | 1 |
| Cheng, WC | 1 |
| Chang, HW | 1 |
| Hung, YC | 1 |
| Ma, WL | 1 |
| Wang, Y | 2 |
| Jia, Y | 1 |
| Yan, L | 1 |
| Fu, J | 1 |
| Hao, M | 1 |
| Chen, W | 1 |
| Yao, B | 1 |
| Zhao, P | 1 |
| Zhou, Z | 1 |
| Bucher, S | 2 |
| Tête, A | 2 |
| Podechard, N | 2 |
| Liamin, M | 1 |
| Le Guillou, D | 2 |
| Chevanne, M | 2 |
| Coulouarn, C | 1 |
| Imran, M | 1 |
| Gallais, I | 2 |
| Fernier, M | 2 |
| Hamdaoui, Q | 1 |
| Robin, MA | 1 |
| Sergent, O | 3 |
| Fromenty, B | 2 |
| Lagadic-Gossmann, D | 3 |
| Allard, J | 1 |
| Pinon, G | 1 |
| Begriche, K | 1 |
| Ovesen, JL | 1 |
| Fan, Y | 1 |
| Chen, J | 1 |
| Medvedovic, M | 1 |
| Xia, Y | 1 |
| Puga, A | 1 |
| Hardonnière, K | 1 |
| Mograbi, B | 1 |
| Le Ferrec, E | 1 |
| Grova, N | 1 |
| Appenzeller, B | 1 |
| Burel, A | 1 |
| Huc, L | 1 |
| Bortoli, S | 1 |
| Sharma, A | 1 |
| Ray, R | 1 |
| Rajeswari, MR | 2 |
| Naveenkumar, C | 1 |
| Asokkumar, S | 1 |
| Raghunandhakumar, S | 1 |
| Jagan, S | 1 |
| Anandakumar, P | 1 |
| Augustine, TA | 1 |
| Kamaraj, S | 1 |
| Devaki, T | 1 |
| Malhotra, A | 1 |
| Nair, P | 1 |
| Dhawan, DK | 1 |
| Zhang, Z | 1 |
| Kastens, E | 1 |
| Lubet, RA | 1 |
| You, M | 1 |
| Estensen, RD | 1 |
| Jordan, MM | 1 |
| Wiedmann, TS | 1 |
| Galbraith, AR | 1 |
| Steele, VE | 1 |
| Wattenberg, LW | 1 |
| Ghosh, I | 1 |
| Chowdhury, AR | 1 |
| Datta, K | 1 |
| Calaf, GM | 1 |
| Alvarado, ME | 1 |
| Hei, TK | 1 |
| Conaway, CC | 1 |
| Wang, CX | 1 |
| Pittman, B | 1 |
| Yang, YM | 1 |
| Schwartz, JE | 1 |
| Tian, D | 1 |
| McIntee, EJ | 1 |
| Hecht, SS | 1 |
| Chung, FL | 1 |
| Yoshino, I | 1 |
| Maehara, Y | 1 |
| Mitsunaga, SI | 1 |
| Zhang, SY | 1 |
| Ruggeri, BA | 1 |
| Gimenez-Conti, I | 1 |
| Robles, AI | 1 |
| Conti, CJ | 1 |
| Klein-Szanto, AJ | 1 |
| Parsons, BL | 1 |
| Culp, SJ | 1 |
| Manjanatha, MG | 1 |
| Heflich, RH | 1 |
1 review available for benzo(a)pyrene and Disease Exacerbation
| Article | Year |
|---|---|
Impact of smoking status on the biological behavior of lung cancer.
Topics: Acid Anhydride Hydrolases; Basic Helix-Loop-Helix Transcription Factors; Benzo(a)pyrene; Biomarkers; | 2007 |
17 other studies available for benzo(a)pyrene and Disease Exacerbation
| Article | Year |
|---|---|
6-Gingerol delays tumorigenesis in benzo[a]pyrene and dextran sulphate sodium-induced colorectal cancer in mice.
Topics: Animals; Benzo(a)pyrene; beta Catenin; Catechols; Colorectal Neoplasms; Dextran Sulfate; Disease Pro | 2020 |
Short androgen receptor poly-glutamine-promoted endometrial cancer is associated with benzo[a]pyrene-mediated aryl hydrocarbon receptor activation.
Topics: Adult; Aged; Benzo(a)pyrene; Cell Line, Tumor; Cell Proliferation; Disease Progression; Endometrial | 2018 |
Clusterin and neuropilin-2 as potential biomarkers of tumor progression in benzo[a]pyrene-transformed 16HBE cells xenografted nude mouse model.
Topics: Animals; Area Under Curve; Benzo(a)pyrene; Biomarkers, Tumor; Carcinogens; Cell Line; Cell Transform | 2017 |
Co-exposure to benzo[a]pyrene and ethanol induces a pathological progression of liver steatosis in vitro and in vivo.
Topics: Animals; Benzo(a)pyrene; Biomarkers; Cell Line; Disease Models, Animal; Disease Progression; Environ | 2018 |
Possible Involvement of Mitochondrial Dysfunction and Oxidative Stress in a Cellular Model of NAFLD Progression Induced by Benzo[a]pyrene/Ethanol CoExposure.
Topics: Benzo(a)pyrene; Disease Progression; Ethanol; Humans; Mitochondria; Non-alcoholic Fatty Liver Diseas | 2018 |
Long-term exposure to low-concentrations of Cr(VI) induce DNA damage and disrupt the transcriptional response to benzo[a]pyrene.
Topics: Animals; Apoptosis; Benzo(a)pyrene; Carcinogens, Environmental; Cell Line, Tumor; Chromium; Colony-F | 2014 |
Role for the ATPase inhibitory factor 1 in the environmental carcinogen-induced Warburg phenotype.
Topics: Animals; Apoptosis; ATPase Inhibitory Protein; Benzo(a)pyrene; Carcinogens, Environmental; Carcinoma | 2017 |
Overexpression of high mobility group (HMG) B1 and B2 proteins directly correlates with the progression of squamous cell carcinoma in skin.
Topics: Animals; Benzo(a)pyrene; Carcinoma, Squamous Cell; Cell Differentiation; Disease Progression; DNA Re | 2008 |
Potent antitumor and antineoplastic efficacy of baicalein on benzo(a)pyrene-induced experimental pulmonary tumorigenesis.
Topics: Adenocarcinoma; Administration, Oral; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phyto | 2012 |
Curcumin and resveratrol synergistically stimulate p21 and regulate cox-2 by maintaining adequate zinc levels during lung carcinogenesis.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzo(a)pyrene; Blotting, Western; Body Wei | 2011 |
Mice with alterations in both p53 and Ink4a/Arf display a striking increase in lung tumor multiplicity and progression: differential chemopreventive effect of budesonide in wild-type and mutant A/J mice.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Budesonide; Carcinogens; Cyclin-De | 2003 |
Effect of chemopreventive agents on separate stages of progression of benzo[alpha]pyrene induced lung tumors in A/J mice.
Topics: Adenoma; Aerosols; Animals; Anti-Inflammatory Agents; Benzo(a)pyrene; Budesonide; Carcinogens; Disea | 2004 |
Differential expression of Hyaluronic Acid Binding Protein 1 (HABP1)/P32/C1QBP during progression of epidermal carcinoma.
Topics: Animals; Benzo(a)pyrene; Carcinogens; Carcinoma; Disease Progression; Gene Expression Profiling; Gen | 2004 |
Beta catenin is associated with breast cancer progression in vitro.
Topics: Benzo(a)pyrene; beta Catenin; Breast Neoplasms; Cell Transformation, Neoplastic; Cytoskeletal Protei | 2005 |
Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice.
Topics: Acetylcysteine; Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Body Weig | 2005 |
Positive immunohistochemical staining of p53 and cyclin D in advanced mouse skin tumors, but not in precancerous lesions produced by benzo[a]pyrene.
Topics: Animals; Benzo(a)pyrene; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cyclins; Disease Progression; | 1995 |
Occurrence of H-ras codon 61 CAA to AAA mutation during mouse liver tumor progression.
Topics: Adenine; Animals; Benzo(a)pyrene; Carcinogens; Coal Tar; Codon; Cytosine; Disease Progression; Genes | 2002 |