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benzo(a)pyrene and Disease, Pulmonary

benzo(a)pyrene has been researched along with Disease, Pulmonary in 12 studies

Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.

Research Excerpts

ExcerptRelevanceReference
" Here, a new "Bottom-up" approach was proposed to identify miRNAs that are responsible for environmental exposure-induced adverse outcomes."1.72Identifying microRNAs that drive BaP-induced pulmonary effects: Multiple patterns of mechanisms underlying activation of the toxicity pathways. ( Chen, N; Du, C; Guan, H; Jin, Y; Li, C; Liu, Y; Luo, J; Ma, W; Shou, Y; Xu, L; Yu, D; Zhang, Q; Zhao, K; Zheng, Y, 2022)
" For both lung and stomach cancers, significant dose-response gradients were observed for exposure to total dust and benzo(a)pyrene, but not for specific chemical components of dust."1.29Cancer risks among iron and steel workers in Anshan, China, Part II: Case-control studies of lung and stomach cancer. ( Blot, WJ; Brown, LM; Cao, RM; Dosemeci, M; Fraumeni, JF; Gao, GS; Guan, DX; Liu, TF; Pan, GW; Sheng, JH; Stone, BJ; Xu, Z; Yan, ZS, 1996)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19903 (25.00)18.7374
1990's4 (33.33)18.2507
2000's2 (16.67)29.6817
2010's1 (8.33)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Jin, Y1
Zhang, Q1
Liu, Y1
Guan, H1
Shou, Y1
Du, C1
Luo, J1
Zhao, K1
Li, C1
Xu, L1
Ma, W1
Chen, N1
Zheng, Y1
Yu, D1
Khattab, SA1
Hussien, WF1
Raafat, N1
Ahmed Alaa El-Din, E1
Latif, IK1
Karim, AJ1
Zuki, AB1
Zamri-Saad, M1
Niu, JP1
Noordin, MM1
Godleski, JJ1
Melnicoff, MJ1
Sadri, S1
Garbeil, P1
Xu, Z1
Brown, LM1
Pan, GW1
Liu, TF1
Gao, GS1
Stone, BJ1
Cao, RM1
Guan, DX1
Sheng, JH1
Yan, ZS1
Dosemeci, M1
Fraumeni, JF1
Blot, WJ1
Shultz, MA1
Morin, D1
Chang, AM1
Buckpitt, A1
Garçon, G1
Garry, S1
Gosset, P1
Zerimech, F1
Martin, A1
Hannothiaux, M1
Shirali, P1
Alexandrov, K1
Rojas, M1
Geneste, O1
Castegnaro, M1
Camus, AM1
Petruzzelli, S1
Giuntini, C1
Bartsch, H1
Bluhm, C1
Cohen, GM1
McClellan, RO1
Mauderly, JL1
Jones, RK1
Cuddihy, RG1
Roth, RA1

Reviews

2 reviews available for benzo(a)pyrene and Disease, Pulmonary

ArticleYear
Pulmonary metabolism of foreign compounds: its role in metabolic activation.
    Environmental health perspectives, 1990, Volume: 85

    Topics: Animals; Benzo(a)pyrene; Epithelium; Humans; Hydrolysis; Lung Diseases; Microsomes; Oxidation-Reduct

1990
Biochemistry, physiology and drug metabolism--implications regarding the role of the lungs in drug disposition.
    Clinical physiology and biochemistry, 1985, Volume: 3, Issue:2-3

    Topics: Amines; Animals; Benzo(a)pyrene; Kinetics; Lung; Lung Diseases; Metabolic Clearance Rate; Pharmaceut

1985

Other Studies

10 other studies available for benzo(a)pyrene and Disease, Pulmonary

ArticleYear
Identifying microRNAs that drive BaP-induced pulmonary effects: Multiple patterns of mechanisms underlying activation of the toxicity pathways.
    Environment international, 2022, Volume: 170

    Topics: Benzo(a)pyrene; Cell Line; Epigenomics; Humans; Lung Diseases; MicroRNAs; RNA, Messenger

2022
Effects of catechin hydrate in benzo[
    Toxicology mechanisms and methods, 2021, Volume: 31, Issue:6

    Topics: Animals; Apoptosis; Benzo(a)pyrene; Catechin; DNA Damage; Lung; Lung Diseases; Male; Oxidative Stres

2021
Pulmonary modulation of benzo[a]pyrene-induced hemato- and hepatotoxicity in broilers.
    Poultry science, 2010, Volume: 89, Issue:7

    Topics: Air Pollutants; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Be

2010
Effects of inhaled ammonium sulfate on benzo[a]pyrene carcinogenesis.
    Journal of toxicology and environmental health, 1984, Volume: 14, Issue:2-3

    Topics: Ammonium Sulfate; Animals; Benzo(a)pyrene; Biotransformation; Body Weight; Cricetinae; Lung Diseases

1984
Cancer risks among iron and steel workers in Anshan, China, Part II: Case-control studies of lung and stomach cancer.
    American journal of industrial medicine, 1996, Volume: 30, Issue:1

    Topics: Adult; Aged; Benzo(a)pyrene; Case-Control Studies; China; Dust; Educational Status; Environmental Po

1996
Metabolic capabilities of CYP2F2 with various pulmonary toxicants and its relative abundance in mouse lung subcompartments.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:2

    Topics: Animals; Anthracenes; Benzo(a)pyrene; Biotransformation; Catalysis; Cytochrome P-450 Enzyme System;

2001
Benzo(a)pyrene-coated onto Fe(2)O(3) particles-induced lung tissue injury: role of free radicals.
    Cancer letters, 2001, Jun-10, Volume: 167, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Benzo(a)pyrene; Bronchoalveolar Lavage Fluid; Deoxyguanosine;

2001
An improved fluorometric assay for dosimetry of benzo(a)pyrene diol-epoxide-DNA adducts in smokers' lung: comparisons with total bulky adducts and aryl hydrocarbon hydroxylase activity.
    Cancer research, 1992, Nov-15, Volume: 52, Issue:22

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adult; Aged; Animals; Aryl Hydrocarbon Hydroxyla

1992
Effects of smoking on benzo(alpha)pyrene- and glutathione-metabolizing enzymes in human lung tissue.
    Klinische Wochenschrift, 1991, Nov-15, Volume: 69, Issue:18

    Topics: 7-Alkoxycoumarin O-Dealkylase; Adenocarcinoma; Adult; Aged; Benzo(a)pyrene; Carcinoma, Small Cell; C

1991
Health effects of diesel exhaust. A contemporary air pollution issue.
    Postgraduate medicine, 1985, Nov-01, Volume: 78, Issue:6

    Topics: Animals; Benzo(a)pyrene; Epidemiologic Methods; Fuel Oils; Humans; Lung Diseases; Lung Neoplasms; Mu

1985