benzo(a)pyrene has been researched along with Chromosome-Defective Micronuclei in 46 studies
Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Reports of the ability of estrogenic agents such as 17beta-estradiol (E2), estriol (E3) and bisphenol A (BPA) to induce micronuclei (MN) in MCF-7 breast cancer cells have prompted us to investigate whether these effects are linked to activation of the estrogen receptor (ER) alpha." | 3.74 | Estrogens and genomic instability in human breast cancer cells--involvement of Src/Raf/Erk signaling in micronucleus formation by estrogenic chemicals. ( Kabil, A; Kortenkamp, A; Silva, E, 2008) |
| "Rutin is a flavonoid with antioxidant, vasodilatory, anti-inflammatory and immune-stimulating activities." | 1.37 | Investigation of cytotoxic, apoptosis-inducing, genotoxic and protective effects of the flavonoid rutin in HTC hepatic cells. ( Beatriz Hoffmann-Campo, C; Cabral Luiz, R; Cristina Marcarini, J; Ferreira Tsuboy, MS; Regina Ribeiro, L; Ségio Mantovani, M, 2011) |
| " Muta™Mouse were dosed daily for 28 days with benzo[a]pyrene (BaP; 0, 25, 50 and 75 mg/kg body weight/day) by oral gavage." | 1.37 | Simultaneous measurement of benzo[a]pyrene-induced Pig-a and lacZ mutations, micronuclei and DNA adducts in Muta™ Mouse. ( Arlt, VM; Dertinger, SD; Douglas, GR; Gingerich, J; Lemieux, CL; Phillips, DH; Phonethepswath, S; Torous, DK; White, PA, 2011) |
| " Adverse effects of B(a)P were tested by cytokinesis-block micronucleus (CBMN) cytome assays." | 1.36 | [Cytotoxicity and genomic damage of benzo[a]pyrene in gene transformed cell model]. ( Bin, P; Chen, W; Dai, YF; Duan, HW; Liu, Q; Liu, QJ; Niu, Y; Wang, YD; Zheng, YX, 2010) |
| " However, the toxic effects and related mechanism of co-exposure to BaP and PCB126 remain unknown." | 1.35 | PCB126 enhanced the genotoxicity of BaP in HepG2 cells by modulating metabolic enzyme and DNA repair activities. ( Chen, XM; Liu, AL; Lu, WQ; Wei, W; Xie, SH; Zhang, C, 2009) |
| "Pretreatment with lupeol (1 mg/animal) and MPE (1 mL, 20%) was given through oral intubation for 7 days prior to B[a]P administration." | 1.35 | Protective effects of lupeol against benzo[a]pyrene induced clastogenicity in mouse bone marrow cells. ( Kumar Yadav, V; Prasad, S; Shukla, Y; Srivastava, S, 2008) |
| "The induction of BaP and CP induced chromosomal aberrations, micronuclei formation, and sister chromatid exchanges (SCEs) were found to be inhibited in a dose-dependent manner by DAS, I3C, CUR, and BTP." | 1.32 | Antigenotoxic potential of certain dietary constituents. ( Arora, A; Shukla, Y; Taneja, P, 2003) |
| " Inhibition of genotoxicity by spinach and peaches was not caused by any delay in maturation of micronucleated erythrocytes as shown by experiments with sampling times of 24, 48, and 72 h after dosing of BaP." | 1.32 | Inhibition of clastogenicity of benzo[a]pyrene and of its trans-7,8-dihydrodiol in mice in vivo by fruits, vegetables, and flavonoids. ( Edenharder, R; Köttgen, V; Krieg, H; Platt, KL, 2003) |
| "Occasionally, B[a]P induced chromosomal aberrations and micronuclei, and diMeDBC induced micronuclei, but not chromosomal aberrations." | 1.31 | Effect of dietary intake of vitamin A or E on the level of DNA damage, chromosomal aberrations, and micronuclei induced in freshly isolated rat hepatocytes by different carcinogens. ( Bacová, G; Barancoková, M; Bezek, S; Bresgen, N; Chalupa, I; Eckl, P; Farkasová, T; Gábelová, A; Hrusovská, L; Kazimírová, A; Navarová, J; Robichová, S; Schneider, P; Sebová, L; Slamenová, D; Wsólová, L; Zeitheim, P, 2002) |
| " A dose-response relationship was observed after exposing RTG-2 cells to vincristine sulfate and benzo(a)pyrene." | 1.31 | Flow cytometric detection of micronuclei and cell cycle alterations in fish-derived cells after exposure to three model genotoxic agents: mitomycin C, vincristine sulfate and benzo(a)pyrene. ( Castaño, A; Llorente, MT; Sánchez, P, 2000) |
| "Coumarin treatment alone did not induce micronuclei in either sex." | 1.28 | Coumarin inhibits micronuclei formation induced by benzo(a)pyrene in male but not female ICR mice. ( Morris, DL; Ward, JB, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 14 (30.43) | 18.2507 |
| 2000's | 17 (36.96) | 29.6817 |
| 2010's | 12 (26.09) | 24.3611 |
| 2020's | 3 (6.52) | 2.80 |
| Authors | Studies |
|---|---|
| Vivarelli, F | 1 |
| Canistro, D | 1 |
| Cirillo, S | 1 |
| Papi, A | 1 |
| Spisni, E | 1 |
| Vornoli, A | 1 |
| Croce, CMD | 1 |
| Longo, V | 1 |
| Franchi, P | 1 |
| Filippi, S | 1 |
| Lucarini, M | 1 |
| Zanzi, C | 1 |
| Rotondo, F | 1 |
| Lorenzini, A | 1 |
| Marchionni, S | 1 |
| Paolini, M | 1 |
| Motwani, HV | 1 |
| Westberg, E | 1 |
| Lindh, C | 1 |
| Abramsson-Zetterberg, L | 1 |
| Törnqvist, M | 1 |
| Smart, DJ | 1 |
| Helbling, FR | 1 |
| Verardo, M | 1 |
| Huber, A | 1 |
| McHugh, D | 1 |
| Vanscheeuwijck, P | 1 |
| Liu, W | 1 |
| Xi, J | 1 |
| Cao, Y | 1 |
| You, X | 1 |
| Chen, R | 1 |
| Zhang, X | 1 |
| Han, L | 1 |
| Pan, G | 1 |
| Luan, Y | 1 |
| Hori, H | 1 |
| Shimoyoshi, S | 1 |
| Tanaka, Y | 1 |
| Momonami, A | 1 |
| Masumura, K | 1 |
| Yamada, M | 1 |
| Fujii, W | 1 |
| Kitagawa, Y | 1 |
| Zhu, N | 1 |
| Hu, K | 1 |
| Li, Z | 1 |
| Chen, Y | 1 |
| Liu, Y | 1 |
| Gábelová, A | 2 |
| Poláková, V | 1 |
| Prochazka, G | 1 |
| Kretová, M | 1 |
| Poloncová, K | 1 |
| Regendová, E | 1 |
| Luciaková, K | 1 |
| Segerbäck, D | 1 |
| Kabil, A | 1 |
| Silva, E | 1 |
| Kortenkamp, A | 1 |
| Wei, W | 2 |
| Zhang, C | 2 |
| Liu, AL | 2 |
| Xie, SH | 2 |
| Chen, XM | 2 |
| Lu, WQ | 2 |
| Angeli, JP | 1 |
| Barcelos, GR | 1 |
| Serpeloni, JM | 1 |
| Barbosa, F | 1 |
| Nersesyan, A | 1 |
| Mantovani, MS | 1 |
| Cristina Marcarini, J | 1 |
| Ferreira Tsuboy, MS | 1 |
| Cabral Luiz, R | 1 |
| Regina Ribeiro, L | 1 |
| Beatriz Hoffmann-Campo, C | 1 |
| Ségio Mantovani, M | 1 |
| Duan, HW | 1 |
| Bin, P | 1 |
| Liu, QJ | 1 |
| Wang, YD | 1 |
| Niu, Y | 1 |
| Liu, Q | 1 |
| Dai, YF | 1 |
| Chen, W | 1 |
| Zheng, YX | 1 |
| Rossnerova, A | 1 |
| Spatova, M | 1 |
| Pastorkova, A | 1 |
| Tabashidze, N | 1 |
| Veleminsky, M | 1 |
| Balascak, I | 1 |
| Solansky, I | 1 |
| Sram, RJ | 1 |
| Lemieux, CL | 1 |
| Douglas, GR | 1 |
| Gingerich, J | 1 |
| Phonethepswath, S | 1 |
| Torous, DK | 1 |
| Dertinger, SD | 2 |
| Phillips, DH | 1 |
| Arlt, VM | 1 |
| White, PA | 1 |
| Sehgal, A | 1 |
| Kumar, M | 1 |
| Jain, M | 1 |
| Dhawan, DK | 2 |
| Madrigal-Santillán, E | 1 |
| Fragoso-Antonio, S | 1 |
| Valadez-Vega, C | 1 |
| Solano-Solano, G | 1 |
| Pérez, CZ | 1 |
| Sánchez-Gutiérrez, M | 1 |
| Izquierdo-Vega, JA | 1 |
| Gutiérrez-Salinas, J | 1 |
| Esquivel-Soto, J | 1 |
| Esquivel-Chirino, C | 1 |
| Sumaya-Martínez, T | 1 |
| Fregoso-Aguilar, T | 1 |
| Mendoza-Pérez, J | 1 |
| Morales-González, JA | 1 |
| Malhotra, A | 1 |
| Nair, P | 1 |
| Davis, C | 1 |
| Bhana, S | 1 |
| Shorrocks, AJ | 1 |
| Martin, FL | 2 |
| Slamenová, D | 1 |
| Chalupa, I | 1 |
| Robichová, S | 1 |
| Farkasová, T | 1 |
| Hrusovská, L | 1 |
| Bacová, G | 1 |
| Sebová, L | 1 |
| Eckl, P | 1 |
| Bresgen, N | 1 |
| Zeitheim, P | 1 |
| Schneider, P | 1 |
| Wsólová, L | 1 |
| Barancoková, M | 1 |
| Kazimírová, A | 1 |
| Navarová, J | 1 |
| Bezek, S | 1 |
| Shukla, Y | 2 |
| Arora, A | 1 |
| Taneja, P | 1 |
| Cho, YH | 1 |
| Chung, HW | 1 |
| Edenharder, R | 1 |
| Krieg, H | 1 |
| Köttgen, V | 1 |
| Platt, KL | 1 |
| Stoncius, D | 1 |
| Lazutka, JR | 1 |
| Selvendiran, K | 1 |
| Padmavathi, R | 1 |
| Magesh, V | 1 |
| Sakthisekaran, D | 1 |
| Khan, TH | 1 |
| Prasad, L | 1 |
| Sultana, S | 1 |
| Lewińska, D | 1 |
| Arkusz, J | 1 |
| Stańczyk, M | 1 |
| Palus, J | 1 |
| Dziubałtowska, E | 1 |
| Stepnik, M | 1 |
| Hewitt, R | 1 |
| Forero, A | 1 |
| Luncsford, PJ | 1 |
| Prasad, S | 1 |
| Kumar Yadav, V | 1 |
| Srivastava, S | 1 |
| Warshawsky, D | 1 |
| Livingston, GK | 1 |
| Fonouni-Fard, M | 1 |
| LaDow, K | 1 |
| Vienneau, DS | 1 |
| DeBoni, U | 1 |
| Wells, PG | 2 |
| Konopacka, M | 1 |
| De Flora, S | 1 |
| Izzotti, A | 1 |
| D'Agostini, F | 1 |
| Rossi, GA | 1 |
| Balansky, RM | 1 |
| Marks, HS | 1 |
| Anderson, JA | 1 |
| Stoewsand, GS | 1 |
| Canova, S | 1 |
| Viezzer, C | 1 |
| Venier, P | 1 |
| Navazio, L | 1 |
| Revoltella, R | 1 |
| Celotti, L | 1 |
| Kim, PM | 1 |
| van Agen, B | 1 |
| Maas, LM | 1 |
| Zwingmann, IH | 1 |
| Van Schooten, FJ | 1 |
| Kleinjans, JC | 1 |
| Han, C | 1 |
| Jing, JX | 1 |
| Sun, GX | 1 |
| Surh, YJ | 1 |
| Kim, SG | 1 |
| Liem, A | 1 |
| Lee, JW | 1 |
| Miller, JA | 1 |
| Sánchez, P | 1 |
| Llorente, MT | 1 |
| Castaño, A | 1 |
| Nazarenko, DA | 1 |
| Silverstone, AE | 1 |
| Gasiewicz, TA | 1 |
| Onaran, I | 1 |
| Güven, G | 1 |
| Ozaydin, A | 1 |
| Ulutin, T | 1 |
| Wang, G | 1 |
| Jia, M | 1 |
| Zhao, S | 1 |
| Li, J | 1 |
| Heo, MY | 1 |
| Yu, KS | 1 |
| Kim, KH | 1 |
| Kim, HP | 1 |
| Au, WW | 1 |
| Lo Jacono, F | 1 |
| Stecca, C | 1 |
| Duverger, M | 1 |
| Morris, DL | 1 |
| Ward, JB | 1 |
46 other studies available for benzo(a)pyrene and Chromosome-Defective Micronuclei
| Article | Year |
|---|---|
Co-carcinogenic effects of vitamin E in prostate.
Topics: 3T3 Cells; Animals; Benzo(a)pyrene; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cytochr | 2019 |
Serum albumin adducts, DNA adducts and micronuclei frequency measured in benzo[a]pyrene-exposed mice for estimation of genotoxic potency.
Topics: Animals; Benzo(a)pyrene; Biotransformation; Carcinogens; DNA Adducts; Epoxy Compounds; Injections, I | 2020 |
Development of an integrated assay in human TK6 cells to permit comprehensive genotoxicity analysis in vitro.
Topics: 4-Nitroquinoline-1-oxide; Benzo(a)pyrene; Cell Line, Tumor; Cyclophosphamide; Diclofenac; DNA; DNA D | 2020 |
An Adaption of Human-Induced Hepatocytes to In Vitro Genetic Toxicity Tests.
Topics: Aflatoxin B1; Benzo(a)pyrene; Cells, Cultured; Comet Assay; Cyclophosphamide; Cytochrome P-450 Enzym | 2019 |
Integration of micronucleus tests with a gene mutation assay in F344 gpt delta transgenic rats using benzo[a]pyrene.
Topics: Animals; Benzo(a)pyrene; Bone Marrow; Carcinogens; Colon; Liver; Male; Micronuclei, Chromosome-Defec | 2019 |
Micronuclei Formation by Promutagens in Metabolism-Incompetent V79 Cells Interacting With Activation-Proficient Cells in Various Experimental Settings.
Topics: Aflatoxin B1; Animals; Arylsulfotransferase; Benzo(a)pyrene; Cell Line; Cricetinae; Cytochrome P-450 | 2020 |
Sustained induction of cytochrome P4501A1 in human hepatoma cells by co-exposure to benzo[a]pyrene and 7H-dibenzo[c,g]carbazole underlies the synergistic effects on DNA adduct formation.
Topics: Animals; Benzo(a)pyrene; Carbazoles; Carcinogens; Carcinoma, Hepatocellular; Cell Line; Cricetinae; | 2013 |
Estrogens and genomic instability in human breast cancer cells--involvement of Src/Raf/Erk signaling in micronucleus formation by estrogenic chemicals.
Topics: Benzhydryl Compounds; Benzo(a)pyrene; Breast Neoplasms; Cell Line, Tumor; Estradiol; Estrogens; Extr | 2008 |
Effect of PCB153 on BaP-induced genotoxicity in HepG2 cells via modulation of metabolic enzymes.
Topics: Benzo(a)pyrene; Benzoflavones; Cell Line, Tumor; Cytochrome P-450 CYP1A1; Dose-Response Relationship | 2009 |
PCB126 enhanced the genotoxicity of BaP in HepG2 cells by modulating metabolic enzyme and DNA repair activities.
Topics: Benzo(a)pyrene; Cell Line, Tumor; Cytochrome P-450 CYP1A1; DNA Repair; DNA-Binding Proteins; Dose-Re | 2009 |
Evaluation of the genotoxic and anti-genotoxic activities of silybin in human hepatoma cells (HepG2).
Topics: Aflatoxin B1; Benzo(a)pyrene; Bleomycin; Carcinoma, Hepatocellular; Cell Death; Cell Division; Cell | 2010 |
Investigation of cytotoxic, apoptosis-inducing, genotoxic and protective effects of the flavonoid rutin in HTC hepatic cells.
Topics: Animals; Antimutagenic Agents; Apoptosis; Benzo(a)pyrene; Cell Line, Tumor; Cell Proliferation; Cell | 2011 |
[Cytotoxicity and genomic damage of benzo[a]pyrene in gene transformed cell model].
Topics: Apoptosis; Benzo(a)pyrene; Cell Division; Cell Line, Transformed; DNA Damage; Humans; Micronuclei, C | 2010 |
Micronuclei levels in mothers and their newborns from regions with different types of air pollution.
Topics: Adolescent; Adult; Air Pollutants; Benzene; Benzo(a)pyrene; Body Mass Index; Czech Republic; Female; | 2011 |
Simultaneous measurement of benzo[a]pyrene-induced Pig-a and lacZ mutations, micronuclei and DNA adducts in Muta™ Mouse.
Topics: Animals; Benzo(a)pyrene; CD24 Antigen; Data Interpretation, Statistical; DNA Adducts; Dose-Response | 2011 |
Piperine as an adjuvant increases the efficacy of curcumin in mitigating benzo(a)pyrene toxicity.
Topics: Alkaloids; Animals; Antimutagenic Agents; Antioxidants; Benzo(a)pyrene; Benzodioxoles; Carcinogens; | 2012 |
Investigation on the protective effects of cranberry against the DNA damage induced by benzo[a]pyrene.
Topics: Animals; Antioxidants; Benzo(a)pyrene; DNA Damage; Dose-Response Relationship, Drug; Male; Mice; Mic | 2012 |
Curcumin and resveratrol in combination modulates benzo(a)pyrene-induced genotoxicity during lung carcinogenesis.
Topics: Animals; Antimutagenic Agents; Apoptosis; Benzo(a)pyrene; Carcinogens; Curcumin; Disease Models, Ani | 2012 |
Oestrogens induce G(1) arrest in benzo[a]pyrene-treated MCF-7 breast cells whilst enhancing genotoxicity and clonogenic survival.
Topics: Benzo(a)pyrene; Breast Neoplasms; Cell Division; Cell Survival; Colony-Forming Units Assay; DNA Dama | 2002 |
Effect of dietary intake of vitamin A or E on the level of DNA damage, chromosomal aberrations, and micronuclei induced in freshly isolated rat hepatocytes by different carcinogens.
Topics: Animals; Benzo(a)pyrene; Carbazoles; Carcinogens; Cells, Cultured; Chromosome Aberrations; DNA Damag | 2002 |
Antigenotoxic potential of certain dietary constituents.
Topics: Allyl Compounds; Animals; Antimutagenic Agents; Benzo(a)pyrene; Bone Marrow Cells; Chromosome Aberra | 2003 |
The effect of extremely low frequency electromagnetic fields (ELF-EMF) on the frequency of micronuclei and sister chromatid exchange in human lymphocytes induced by benzo(a)pyrene.
Topics: Benzo(a)pyrene; Cells, Cultured; Dose-Response Relationship, Drug; Dose-Response Relationship, Radia | 2003 |
Inhibition of clastogenicity of benzo[a]pyrene and of its trans-7,8-dihydrodiol in mice in vivo by fruits, vegetables, and flavonoids.
Topics: Administration, Oral; Animals; Antimutagenic Agents; Benzo(a)pyrene; Bone Marrow Cells; Cytochrome P | 2003 |
Spontaneous and benzo[a]pyrene-induced micronuclei in the embryos of the black-headed gull (Larus ridibundus L.).
Topics: Animals; Benzo(a)pyrene; Birds; Embryo, Nonmammalian; Environmental Monitoring; Erythrocytes; Lithua | 2003 |
Preliminary study on inhibition of genotoxicity by piperine in mice.
Topics: Alkaloids; Animals; Antimutagenic Agents; Benzo(a)pyrene; Benzodioxoles; Cyclophosphamide; Dose-Resp | 2005 |
Soy isoflavones inhibits the genotoxicity of benzo(a)pyrene in Swiss albino mice.
Topics: Animals; Antimutagenic Agents; Benzo(a)pyrene; Bone Marrow Cells; Chemoprevention; Cytochrome P-450 | 2005 |
Comparison of the effects of arsenic and cadmium on benzo(a)pyrene-induced micronuclei in mouse bone-marrow.
Topics: Animals; Arsenic; Benzo(a)pyrene; Bone Marrow; Cadmium; Drug Interactions; Male; Mice; Mice, Inbred | 2007 |
Enhanced micronucleus formation and modulation of BCL-2:BAX in MCF-7 cells after exposure to binary mixtures.
Topics: bcl-2-Associated X Protein; Benzo(a)pyrene; Breast Neoplasms; Cell Line, Tumor; Cyclin-Dependent Kin | 2007 |
Protective effects of lupeol against benzo[a]pyrene induced clastogenicity in mouse bone marrow cells.
Topics: Animals; Antimutagenic Agents; Antineoplastic Agents, Phytogenic; Benzo(a)pyrene; Bone Marrow Cells; | 2008 |
Induction of micronuclei and sister chromatid exchanges by polycyclic and N-heterocyclic aromatic hydrocarbons in cultured human lymphocytes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult; Benz(a)Anthracenes; Benzo(a)pyrene; Carbazoles; Carcinogens | 1995 |
Potential genoprotective role for UDP-glucuronosyltransferases in chemical carcinogenesis: initiation of micronuclei by benzo(a)pyrene and benzo(e)pyrene in UDP-glucuronosyltransferase-deficient cultured rat skin fibroblasts.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Bilirubin; Cells, Cultured; Cocarcinogenesis; Fibroblasts; Gl | 1995 |
Evaluation of frequency of micronuclei in exfoliated cells from bladder of mice treated with benzo(a) pyrene, 2-acetylaminofluorene and cyclophosphamide.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Cell Count; Cyclophosphamide; Epithelium; Male; Mice | 1994 |
Pulmonary alveolar macrophages in molecular epidemiology and chemoprevention of cancer.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Acetylcysteine; Adolescent; Adult; Aged; Animals | 1993 |
Effect of S-methyl cysteine sulphoxide and its metabolite methyl methane thiosulphinate, both occurring naturally in Brassica vegetables, on mouse genotoxicity.
Topics: Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Bone Marrow; Brassica; Corn Oil; Cysteine; Dose-Re | 1993 |
Metabolic activation of benzo[a]pyrene in two fetal mouse hepatocyte lines: induction of DNA adducts and micronuclei.
Topics: Animals; Autoradiography; Benzo(a)pyrene; Biotransformation; Cell Line; CHO Cells; Chromatography, T | 1996 |
Genoprotection by UDP-glucuronosyltransferases in peroxidase-dependent, reactive oxygen species-mediated micronucleus initiation by the carcinogens 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and benzo[a]pyrene.
Topics: Animals; Benzo(a)pyrene; Carcinogens; Cells, Cultured; Cytochrome P-450 Enzyme System; Glucuronosylt | 1996 |
B[a]P-DNA adduct formation and induction of human epithelial lung cell transformation.
Topics: Benzo(a)pyrene; Cell Cycle; Cell Division; Cell Line; Cell Transformation, Neoplastic; DNA Adducts; | 1997 |
[Study of environmental pollution and damage of cytogenetic materials in urban residents].
Topics: Benzo(a)pyrene; Cells, Cultured; China; Chromosome Aberrations; Environmental Pollution; Female; Hum | 1997 |
Inhibitory effects of isopropyl-2-(1,3-dithietane-2-ylidene)-2- [N-(4-methylthiazol-2-yl)carbamoyl]acetate (YH439) on benzo[a]pyrene-induced skin carcinogenesis and micronucleated reticulocyte formation in mice.
Topics: Animals; Anticarcinogenic Agents; Antimutagenic Agents; Antineoplastic Agents; Benzo(a)pyrene; Cross | 1999 |
Flow cytometric detection of micronuclei and cell cycle alterations in fish-derived cells after exposure to three model genotoxic agents: mitomycin C, vincristine sulfate and benzo(a)pyrene.
Topics: Animals; Benzo(a)pyrene; Cell Cycle; Cell Line; Flow Cytometry; Micronuclei, Chromosome-Defective; M | 2000 |
Aryl hydrocarbon receptor signaling plays a significant role in mediating benzo[a]pyrene- and cigarette smoke condensate-induced cytogenetic damage in vivo.
Topics: Animals; Benzo(a)pyrene; Chromosomes; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2 Inhibitors; D | 2001 |
The influence of GSTM1 null genotype on susceptibility to in vitro oxidative stress.
Topics: Adolescent; Adult; Benzene Derivatives; Benzo(a)pyrene; Cells, Cultured; Female; Genotype; Glutathio | 2001 |
[A study on the relationship between lymphocyte micronucleus rates and blood plasma benzo(a)pyrene levels in coking workers].
Topics: Adult; Benzo(a)pyrene; Coke; Female; Humans; Lymphocytes; Male; Micronuclei, Chromosome-Defective; M | 1999 |
Anticlastogenic effect of flavonoids against mutagen-induced micronuclei in mice.
Topics: Animals; Benzo(a)pyrene; DNA Damage; Dose-Response Relationship, Drug; Drug Antagonism; Flavonoids; | 1992 |
Mutagenic activation of benzo[a]pyrene by human red blood cells.
Topics: Benzo(a)pyrene; Biotransformation; Cells, Cultured; Chromatography, High Pressure Liquid; Dose-Respo | 1992 |
Coumarin inhibits micronuclei formation induced by benzo(a)pyrene in male but not female ICR mice.
Topics: Animals; Benzo(a)pyrene; Bone Marrow; Coumarins; Drug Administration Schedule; Drug Tolerance; Femal | 1992 |