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benzo(a)pyrene and Choriocarcinoma

benzo(a)pyrene has been researched along with Choriocarcinoma in 5 studies

Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.

Choriocarcinoma: A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, SM1
Lee, HM1
Hwang, KA1
Choi, KC1
Karttunen, V1
Myllynen, P1
Prochazka, G1
Pelkonen, O1
Segerbäck, D1
Vähäkangas, K1
Drukteinis, JS1
Medrano, T1
Ablordeppey, EA1
Kitzman, JM1
Shiverick, KT3
Zhang, L2
Connor, EE1
Chegini, N1

Other Studies

5 other studies available for benzo(a)pyrene and Choriocarcinoma

ArticleYear
Benzo(a)pyrene induced cell cycle arrest and apoptosis in human choriocarcinoma cancer cells through reactive oxygen species-induced endoplasmic reticulum-stress pathway.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2017, Volume: 107, Issue:Pt A

    Topics: Apoptosis; Benzo(a)pyrene; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Choriocarc

2017
Placental transfer and DNA binding of benzo(a)pyrene in human placental perfusion.
    Toxicology letters, 2010, Aug-16, Volume: 197, Issue:2

    Topics: Benzo(a)pyrene; Cell Line, Tumor; Choriocarcinoma; Cytochrome P-450 CYP1A1; DNA; DNA Adducts; Dose-R

2010
Benzo[a]pyrene, but not 2,3,7,8-TCDD, induces G2/M cell cycle arrest, p21CIP1 and p53 phosphorylation in human choriocarcinoma JEG-3 cells: a distinct signaling pathway.
    Placenta, 2005, Volume: 26 Suppl A

    Topics: Antioxidants; Benzo(a)pyrene; CDC2 Protein Kinase; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor

2005
Modulation by benzo[a]pyrene of epidermal growth factor receptors, cell proliferation, and secretion of human chorionic gonadotropin in human placental cell lines.
    Biochemical pharmacology, 1995, Oct-12, Volume: 50, Issue:8

    Topics: Benzo(a)pyrene; Carcinogens; Cell Division; Choriocarcinoma; Chorionic Gonadotropin; Cytochrome P-45

1995
Benzo(a)pyrene, but not 2,3,7,8-tetrachlorodibenzo-p-dioxin, alters cell proliferation and c-myc and growth factor expression in human placental choriocarcinoma JEG-3 cells.
    Biochemical and biophysical research communications, 1997, Feb-03, Volume: 231, Issue:1

    Topics: Benzo(a)pyrene; Cell Division; Choriocarcinoma; Cytochrome P-450 CYP1A1; ErbB Receptors; Gene Expres

1997