benzo(a)pyrene has been researched along with Cardiotoxicity in 3 studies
Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Cardiotoxicity: Damage to the HEART or its function secondary to exposure to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that mediates many of the toxic effects of dioxin-like compounds (DLCs) and some polycyclic aromatic hydrocarbons (PAHs)." | 1.42 | Zebrafish cardiotoxicity: the effects of CYP1A inhibition and AHR2 knockdown following exposure to weak aryl hydrocarbon receptor agonists. ( Brown, DR; Clark, BW; Di Giulio, RT; Garner, LV, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| You, Y | 1 |
| Kim, HS | 1 |
| Bae, IH | 1 |
| Lee, SG | 1 |
| Jee, MH | 1 |
| Keum, G | 1 |
| Jang, SK | 1 |
| Kim, BM | 1 |
| Jayasundara, N | 1 |
| Van Tiem Garner, L | 1 |
| Meyer, JN | 1 |
| Erwin, KN | 1 |
| Di Giulio, RT | 2 |
| Brown, DR | 1 |
| Clark, BW | 1 |
| Garner, LV | 1 |
3 other studies available for benzo(a)pyrene and Cardiotoxicity
| Article | Year |
|---|---|
New potent biaryl sulfate-based hepatitis C virus inhibitors.
Topics: Amides; Antiviral Agents; Cardiotoxicity; Drug Discovery; Drug Interactions; ERG1 Potassium Channel; | 2017 |
AHR2-Mediated transcriptomic responses underlying the synergistic cardiac developmental toxicity of PAHs.
Topics: Animals; Benzo(a)pyrene; Calcium; Cardiotoxicity; Drug Synergism; Embryo, Nonmammalian; Embryonic De | 2015 |
Zebrafish cardiotoxicity: the effects of CYP1A inhibition and AHR2 knockdown following exposure to weak aryl hydrocarbon receptor agonists.
Topics: Animals; Benzo(a)pyrene; Cardiotoxicity; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Em | 2015 |