benzo(a)pyrene has been researched along with Carcinoma, Non-Small Cell Lung in 18 studies
Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Osteoclastogenesis and bone resorption activity of H460 cells were increased by BaP‑H460‑CM." | 1.42 | Tricetin, a dietary flavonoid, suppresses benzo(a)pyrene‑induced human non‑small cell lung cancer bone metastasis. ( Chang, WA; Chiang, HH; Chou, SH; Hsu, YL; Huang, MS; Hung, JY; Kuo, PL; Tsai, YM, 2015) |
| "Surprisingly, the incidence of second primary cancer in locally advanced non-small cell lung cancer at 10 years, following cisplatin-based chemotherapy with concurrent radiotherapy, increases to 61%." | 1.34 | Point mutation of K-ras gene in cisplatin-induced lung tumours in A/J mice. ( Hisamoto, A; Hosokawa, S; Kiura, K; Kondo, E; Mimoto, J; Okada, T; Tabata, M; Takigawa, N; Tanimoto, M, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (16.67) | 18.2507 |
| 2000's | 3 (16.67) | 29.6817 |
| 2010's | 9 (50.00) | 24.3611 |
| 2020's | 3 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Ling, J | 1 |
| Wang, Y | 1 |
| Ma, L | 3 |
| Zheng, Y | 2 |
| Tang, H | 1 |
| Meng, L | 1 |
| Zhang, L | 1 |
| Wu, Y | 2 |
| Niu, Y | 1 |
| Leng, J | 1 |
| Xu, J | 1 |
| Chen, H | 1 |
| Li, H | 1 |
| Wang, L | 1 |
| Hu, J | 1 |
| Xia, D | 1 |
| Garg, R | 1 |
| Cooke, M | 1 |
| Benavides, F | 1 |
| Abba, MC | 1 |
| Cicchini, M | 1 |
| Feldser, DM | 1 |
| Kazanietz, MG | 1 |
| Tu, CY | 1 |
| Cheng, FJ | 1 |
| Chen, CM | 1 |
| Wang, SL | 1 |
| Hsiao, YC | 1 |
| Chen, CH | 1 |
| Hsia, TC | 1 |
| He, YH | 1 |
| Wang, BW | 1 |
| Hsieh, IS | 1 |
| Yeh, YL | 1 |
| Tang, CH | 1 |
| Chen, YJ | 1 |
| Huang, WC | 1 |
| Sanchala, D | 1 |
| Bhatt, LK | 1 |
| Pethe, P | 1 |
| Shelat, R | 1 |
| Kulkarni, YA | 1 |
| Ulasli, SS | 1 |
| Celik, S | 1 |
| Gunay, E | 1 |
| Ozdemir, M | 1 |
| Hazman, O | 1 |
| Ozyurek, A | 1 |
| Koyuncu, T | 1 |
| Unlu, M | 1 |
| Sikdar, S | 1 |
| Mukherjee, A | 1 |
| Ghosh, S | 1 |
| Khuda-Bukhsh, AR | 1 |
| Hung, JY | 1 |
| Chang, WA | 1 |
| Tsai, YM | 1 |
| Hsu, YL | 1 |
| Chiang, HH | 1 |
| Chou, SH | 1 |
| Huang, MS | 1 |
| Kuo, PL | 1 |
| Urman, A | 1 |
| Dean Hosgood, H | 1 |
| Yu, XJ | 1 |
| Yang, MJ | 1 |
| Zhou, B | 1 |
| Wang, GZ | 1 |
| Huang, YC | 1 |
| Wu, LC | 1 |
| Cheng, X | 1 |
| Wen, ZS | 1 |
| Huang, JY | 1 |
| Zhang, YD | 1 |
| Gao, XH | 1 |
| Li, GF | 1 |
| He, SW | 1 |
| Gu, ZH | 1 |
| Pan, CM | 1 |
| Wang, P | 1 |
| Chen, HB | 1 |
| Hong, ZP | 1 |
| Wang, XL | 1 |
| Mao, WJ | 1 |
| Jin, XL | 1 |
| Kang, H | 1 |
| Chen, ST | 1 |
| Zhu, YQ | 1 |
| Gu, WY | 1 |
| Liu, Z | 1 |
| Dong, H | 1 |
| Tian, LW | 1 |
| Chen, SJ | 1 |
| Cao, Y | 1 |
| Wang, SY | 1 |
| Zhou, GB | 1 |
| Tang, SC | 1 |
| Sheu, GT | 1 |
| Wong, RH | 1 |
| Huang, CY | 1 |
| Weng, MW | 1 |
| Lee, LW | 1 |
| Hsu, CP | 1 |
| Ko, JL | 1 |
| Li, D | 1 |
| Wang, Q | 1 |
| Liu, C | 1 |
| Duan, H | 1 |
| Zeng, X | 1 |
| Zhang, B | 1 |
| Li, X | 1 |
| Zhao, J | 1 |
| Tang, S | 1 |
| Li, Z | 1 |
| Xing, X | 1 |
| Yang, P | 1 |
| Chen, L | 1 |
| Zeng, J | 1 |
| Zhu, X | 1 |
| Zhang, S | 1 |
| Zhang, Z | 1 |
| He, Z | 1 |
| Wang, E | 1 |
| Xiao, Y | 1 |
| Chen, W | 1 |
| Port, JL | 1 |
| Yamaguchi, K | 1 |
| Du, B | 1 |
| De Lorenzo, M | 1 |
| Chang, M | 1 |
| Heerdt, PM | 1 |
| Kopelovich, L | 1 |
| Marcus, CB | 1 |
| Altorki, NK | 1 |
| Subbaramaiah, K | 1 |
| Dannenberg, AJ | 1 |
| Yohena, T | 1 |
| Yoshino, I | 1 |
| Takenaka, T | 1 |
| Ohba, T | 1 |
| Kouso, H | 1 |
| Osoegawa, A | 1 |
| Hamatake, M | 1 |
| Oda, S | 1 |
| Kuniyoshi, Y | 1 |
| Maehara, Y | 1 |
| Hisamoto, A | 1 |
| Kondo, E | 1 |
| Kiura, K | 1 |
| Okada, T | 1 |
| Hosokawa, S | 1 |
| Mimoto, J | 1 |
| Takigawa, N | 1 |
| Tabata, M | 1 |
| Tanimoto, M | 1 |
| Hammond, WG | 2 |
| Tesluk, H | 1 |
| Benfield, JR | 2 |
| Sawyer, RW | 1 |
| Teplitz, RL | 1 |
| Goto, I | 1 |
| Yoneda, S | 1 |
| Yamamoto, M | 1 |
| Kawajiri, K | 1 |
18 other studies available for benzo(a)pyrene and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
KIF11, a plus end-directed kinesin, as a key gene in benzo(a)pyrene-induced non-small cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Benzo(a)pyrene; Benzopyrans; Carcinogenesis; Carcinoma, Non-Small-Ce | 2022 |
Benzo(a)pyrene regulated A549 cell migration, invasion and epithelial-mesenchymal transition by up-regulating long non-coding RNA linc00673.
Topics: A549 Cells; Antigens, CD; Basic Helix-Loop-Helix Transcription Factors; Benzo(a)pyrene; Cadherins; C | 2020 |
PKC
Topics: Adenocarcinoma of Lung; Animals; Benzo(a)pyrene; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; C | 2020 |
Cigarette smoke enhances oncogene addiction to c-MET and desensitizes EGFR-expressing non-small cell lung cancer to EGFR TKIs.
Topics: Benzo(a)pyrene; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; ErbB Receptors; HEK293 Cells; Huma | 2018 |
Anticancer activity of methylene blue via inhibition of heat shock protein 70.
Topics: A549 Cells; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzo(a)pyrene; Biom | 2018 |
Anticancer effects of thymoquinone, caffeic acid phenethyl ester and resveratrol on A549 non-small cell lung cancer cells exposed to benzo(a)pyrene.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Benzo(a)pyrene; Benzoquinones; Caffeic Acids; Carcinom | 2013 |
Condurango glycoside-rich components stimulate DNA damage-induced cell cycle arrest and ROS-mediated caspase-3 dependent apoptosis through inhibition of cell-proliferation in lung cancer, in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzo(a)pyrene; Carcinogens; Carcinoma, Non-Small-Cell Lu | 2014 |
Tricetin, a dietary flavonoid, suppresses benzo(a)pyrene‑induced human non‑small cell lung cancer bone metastasis.
Topics: Antineoplastic Agents; Benzo(a)pyrene; Bone Neoplasms; Bone Resorption; Carcinoma, Non-Small-Cell Lu | 2015 |
Lung Cancer Risk, Genetic Variation, and Air Pollution.
Topics: Air Pollutants; Air Pollution; Benzo(a)pyrene; Carcinoma, Non-Small-Cell Lung; Female; Humans; Lung | 2015 |
Characterization of Somatic Mutations in Air Pollution-Related Lung Cancer.
Topics: Aged; Air Pollutants; Air Pollution; Base Sequence; Benzo(a)pyrene; Carcinoma, Non-Small-Cell Lung; | 2015 |
Expression of glutathione S-transferase M2 in stage I/II non-small cell lung cancer and alleviation of DNA damage exposure to benzo[a]pyrene.
Topics: Benzo(a)pyrene; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; DNA Damage; DNA | 2010 |
Aberrant expression of miR-638 contributes to benzo(a)pyrene-induced human cell transformation.
Topics: Benzo(a)pyrene; Biomarkers; Biotransformation; BRCA1 Protein; Carcinogens; Carcinoma, Non-Small-Cell | 2012 |
Tobacco smoke induces CYP1B1 in the aerodigestive tract.
Topics: Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cyt | 2004 |
Relationship between the loss of heterozygosity and tobacco smoking in pulmonary adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Benzo(a)pyrene; Carcinoma, Non-Small-Cell Lung; Cell | 2007 |
Point mutation of K-ras gene in cisplatin-induced lung tumours in A/J mice.
Topics: Adenocarcinoma; Animals; Benzo(a)pyrene; Carcinogens; Carcinoma, Non-Small-Cell Lung; Cisplatin; Cod | 2007 |
Histogenesis of adenosquamous bronchogenic carcinoma.
Topics: Adenocarcinoma; Animals; Benzo(a)pyrene; Carcinogens; Carcinoma, Adenosquamous; Carcinoma, Bronchoge | 1995 |
Regression of bronchial epithelial cancer in hamsters.
Topics: Animals; Benzo(a)pyrene; Carcinoma, Non-Small-Cell Lung; Cricetinae; Female; Lung Neoplasms; Male; M | 1993 |
Prognostic significance of germ line polymorphisms of the CYP1A1 and glutathione S-transferase genes in patients with non-small cell lung cancer.
Topics: Adult; Aged; Benzo(a)pyrene; Carcinoma, Non-Small-Cell Lung; Cytochrome P-450 Enzyme System; Female; | 1996 |