Compounds > benzo(a)pyrene
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benzo(a)pyrene and Carcinoma, Anaplastic

benzo(a)pyrene has been researched along with Carcinoma, Anaplastic in 32 studies

Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.

Research Excerpts

ExcerptRelevanceReference
" Here, we present our results on the expression of HMGA1 in murine skin carcinoma as detected by acid-urea electrophoresis, reverse-phase high-performance liquid chromatography and Western blot."3.71Elevated levels of high-mobility-group chromosomal proteins, HMGA1, in murine skin carcinoma. ( Jain, A; Rajeswari, MR; Ray, R; Singh, D, 2001)
"Lung cancer is the leading cause of cancer mortality in the United States and worldwide."1.36A dominant-negative c-jun mutant inhibits lung carcinogenesis in mice. ( Anderson, MW; Colburn, NH; Estensen, RD; Goodin, C; Tan, Q; Tichelaar, JW; Wang, Y; Yan, Y; Yin, H; You, M; Young, MR, 2010)
"With the onset of metastasis, HABP1 overexpression was confined to metastatic islands, while it disappeared gradually from the surrounding mass."1.32Differential expression of Hyaluronic Acid Binding Protein 1 (HABP1)/P32/C1QBP during progression of epidermal carcinoma. ( Chowdhury, AR; Datta, K; Ghosh, I; Rajeswari, MR, 2004)
" Dose-response studies were conducted at low doses in mouse skin by initiation-promotion and repeated application to compare its activity to that of 7,12-dimethylbenz[a]anthracene (DMBA), benzo[a]pyrene (B[a]P), DB[a,l]P-8,9-dihydrodiol and DB[a,l]P-11,12-dihydrodiol."1.29Tumor-initiating activity and carcinogenicity of dibenzo[a,l]pyrene versus 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene at low doses in mouse skin. ( Cavalieri, EL; Higginbotham, S; Johansson, SL; RamaKrishna, NV; Rogan, EG, 1993)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199010 (31.25)18.7374
1990's5 (15.63)18.2507
2000's13 (40.63)29.6817
2010's2 (6.25)24.3611
2020's2 (6.25)2.80

Authors

AuthorsStudies
V, SK1
S, J1
S, S1
K, P1
S, N1
T, D1
Hýžďalová, M1
Procházková, J1
Strapáčová, S1
Svržková, L1
Vacek, O1
Fedr, R1
Andrysík, Z1
Hrubá, E2
Líbalová, H2
Kléma, J1
Topinka, J2
Mašek, J1
Souček, K2
Vondráček, J3
Machala, M3
Chen, YL1
Fang, JH1
Lai, MD1
Shan, YS1
Gu, Q1
Hu, C1
Chen, Q1
Xia, Y1
Feng, J1
Yang, H1
Chang, JS1
Bae, JT1
Oh, EJ1
Kim, JY1
Park, SH1
Lee, KR2
Tichelaar, JW1
Yan, Y1
Tan, Q1
Wang, Y1
Estensen, RD1
Young, MR1
Colburn, NH1
Yin, H1
Goodin, C1
Anderson, MW1
You, M1
Bryja, V1
N'Guyen, QB1
Fallone, F1
Seree, E1
Fina, F1
Villard, PH1
Guigal, N1
De Meo, M1
Lacarelle, B1
Martin, PM1
Barra, Y1
Lee, BM1
Kim, HS1
Kim, IS1
Ahn, MY1
Chun, SA1
Yoo, SD1
Park, YA1
Choi, SM1
Kim, KB1
Han, SY1
Park, KL1
Kwack, SJ1
Song, HS1
Bae, HJ1
Cho, MH1
PRINA, C1
MAGRASSI, B1
ROVETA, G1
HERROLD, KM2
DUNHAM, LJ1
BAUDYSOVA, M1
HOLECKOVA, E1
SEKLA, B1
THIERY, M1
VANGIJSEGEM, M1
Plísková, M1
Vojtesek, B1
Kozubík, A1
Ghosh, I1
Chowdhury, AR1
Rajeswari, MR2
Datta, K1
Weng, MW1
Lai, JC1
Hsu, CP1
Yu, KY1
Chen, CY1
Lin, TS1
Lai, WW1
Lee, H1
Ko, JL1
Nwagbara, O1
Darling-Reed, SF1
Tucker, A1
Harris, C1
Abazinge, M1
Thomas, RD1
Gragg, RD1
Guarini, A1
Acero, R1
Alessio, G1
Donati, MB1
Semeraro, N1
Mantovani, A1
Kimizuka, G1
Azuma, M1
Ishibashi, M1
Shinozaki, K1
Hayashi, Y1
Higginbotham, S1
RamaKrishna, NV1
Johansson, SL1
Rogan, EG1
Cavalieri, EL1
Culp, SJ1
Gaylor, DW1
Sheldon, WG1
Goldstein, LS1
Beland, FA1
Przygodzki, RM1
Koss, MN1
O'Leary, TJ1
Singh, D1
Jain, A1
Ray, R1
Kammann, U1
Bunke, M1
Steinhart, H1
Theobald, N1
Mello, ML1
Lareef, MH1
Vidal, BC1
Russo, J1
Chagnaud, JL2
Faiderbe, S2
Geffard, M2
Bourême, D1
Yamasaki, H1
Hollstein, M1
Martel, N1
Cabral, JR1
Galendo, D1
Tomatis, L1
Pruess-Schwartz, D1
Baird, WM1
Nikbakht, A1
Merrick, BA1
Selkirk, JK1
Upadhyay, RR1
Ghanayat, P1
Benbehani, AN1
Sanayen, HD1
DePass, LR1
Weil, CS1
Ballantyne, B1
Lewis, SC1
Losco, PE1
Reid, JB1
Simon, GS1

Other Studies

32 other studies available for benzo(a)pyrene and Carcinoma, Anaplastic

ArticleYear
Vanillic acid attenuates cell proliferation, xenobiotic enzyme activity, and the status of pulmonary mitochondrial enzymes in lung carcinoma.
    Journal of food biochemistry, 2022, Volume: 46, Issue:10

    Topics: Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carcinogenesis; Carcinoma; Cell Proliferation; Lun

2022
A prolonged exposure of human lung carcinoma epithelial cells to benzo[a]pyrene induces p21-dependent epithelial-to-mesenchymal transition (EMT)-like phenotype.
    Chemosphere, 2021, Volume: 263

    Topics: Benzo(a)pyrene; Carcinoma; Epithelial Cells; Humans; Lung; Lung Neoplasms; Phenotype; Receptors, Ary

2021
Depletion of CD4(+)CD25(+) regulatory T cells can promote local immunity to suppress tumor growth in benzo[a]pyrene-induced forestomach carcinoma.
    World journal of gastroenterology, 2008, Oct-14, Volume: 14, Issue:38

    Topics: Animals; Antibodies, Monoclonal; Apoptosis; Benzo(a)pyrene; Carcinoma; Cell Proliferation; Female; F

2008
Development of a rat model by 3,4-benzopyrene intra-pulmonary injection and evaluation of the effect of green tea drinking on p53 and bcl-2 expression in lung carcinoma.
    Cancer detection and prevention, 2009, Volume: 32, Issue:5-6

    Topics: Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carcinoma; Chemoprevention; Disease Models, Animal

2009
Cancer preventive potential of methanol extracts of Hypsizigus marmoreus.
    Journal of medicinal food, 2009, Volume: 12, Issue:3

    Topics: Agaricales; Animals; Antimutagenic Agents; Antioxidants; Benzo(a)pyrene; Carcinoma; Cell Line, Tumor

2009
A dominant-negative c-jun mutant inhibits lung carcinogenesis in mice.
    Cancer prevention research (Philadelphia, Pa.), 2010, Volume: 3, Issue:9

    Topics: Animals; Benzo(a)pyrene; Carcinogens; Carcinoma; Cell Transformation, Neoplastic; Cytoprotection; Do

2010
Gene expression changes in human prostate carcinoma cells exposed to genotoxic and nongenotoxic aryl hydrocarbon receptor ligands.
    Toxicology letters, 2011, Oct-10, Volume: 206, Issue:2

    Topics: Benzo(a)pyrene; Carcinogens, Environmental; Carcinoma; Cell Cycle; Cell Line, Tumor; DNA Repair; DNA

2011
Serum increases CYP1A1 induction by 3-methylcholanthrene.
    Biochemical and biophysical research communications, 2002, Sep-20, Volume: 297, Issue:2

    Topics: Adenocarcinoma; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Blood Proteins; Carcinoma; Cattle; Colo

2002
Ras transgene expression in TG-AC mice treated with benzo[a]pyrene.
    Biological & pharmaceutical bulletin, 2003, Volume: 26, Issue:5

    Topics: Animals; Benzo(a)pyrene; Carcinogens; Carcinoma; Female; In Situ Hybridization; Mice; Mice, Transgen

2003
[Complexes of 3,4-benzopyrene and various substances in aqueous solution. Action in vitro and in vivo on Ehrlich's ascites cancer cells].
    Bollettino della Societa italiana di biologia sperimentale, 1962, Dec-15, Volume: 38

    Topics: Animals; Ascites; Benzo(a)pyrene; Benzopyrenes; Caffeine; Carcinoma; Carcinoma, Ehrlich Tumor; Hista

1962
Induction of carcinoma and papilloma of the Syrian hamster by intratracheal instillation of benzo[a]-pyrene.
    Journal of the National Cancer Institute, 1962, Volume: 28

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Bronchi; Carcinoma; Cricetinae; Humans; Mesocricetus; Papillo

1962
THE EFFECTS OF BENZO(A)PYRENE, CIGARETTE SMOKE CONDENSATE AND ATMOSPHERIC POLLUTANTS ON THE RESPIRATORY SYSTEM OF SYRIAN HAMSTERS.
    Acta - Unio Internationalis Contra Cancrum, 1963, Volume: 19

    Topics: Air Pollution; Animals; Benzo(a)pyrene; Benzopyrenes; Bronchial Neoplasms; Carcinogens; Carcinoma; C

1963
THE RESISTANCE OF TWO LINES OF RATS TO TUMOUR INDUCTION BY 3,4-BENZPYRENE.
    Neoplasma, 1964, Volume: 11

    Topics: Animals; Antigens; Benzo(a)pyrene; Benzopyrenes; Carcinoma; Carcinoma 256, Walker; Mortality; Neopla

1964
SPECIES AND STRAIN DIFFERENCES IN THE SUSCEPTIBILITY OF THE CERVICO-VAGINAL SQUAMOUS EPITHELIUM TO 3,4-BENZO(A)PYRENE.
    British journal of cancer, 1965, Volume: 19

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinoma; Carcinoma, Squamous Cell; Cricetinae; Female; Gene

1965
Deregulation of cell proliferation by polycyclic aromatic hydrocarbons in human breast carcinoma MCF-7 cells reflects both genotoxic and nongenotoxic events.
    Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 83, Issue:2

    Topics: Benz(a)Anthracenes; Benzo(a)pyrene; Benzothiazoles; Breast Neoplasms; Bromodeoxyuridine; Carcinogens

2005
Differential expression of Hyaluronic Acid Binding Protein 1 (HABP1)/P32/C1QBP during progression of epidermal carcinoma.
    Molecular and cellular biochemistry, 2004, Volume: 267, Issue:1-2

    Topics: Animals; Benzo(a)pyrene; Carcinogens; Carcinoma; Disease Progression; Gene Expression Profiling; Gen

2004
Alternative splicing of MDM2 mRNA in lung carcinomas and lung cell lines.
    Environmental and molecular mutagenesis, 2005, Volume: 46, Issue:1

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Aged; Alternative Splicing; Benzo(a)pyrene; Carc

2005
Induction of cell death, DNA strand breaks, and cell cycle arrest in DU145 human prostate carcinoma cell line by benzo[a]pyrene and benzo[a]pyrene-7,8-diol-9,10-epoxide.
    International journal of environmental research and public health, 2007, Volume: 4, Issue:1

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benzo(a)pyrene; Carcinogens; Carcinoma; Cell Cyc

2007
Procoagulant activity of macrophages associated with different murine neoplasms.
    International journal of cancer, 1984, Oct-15, Volume: 34, Issue:4

    Topics: Animals; Ascitic Fluid; Benzo(a)pyrene; Blood Coagulation; Carcinoma; Endotoxins; Macrophages; Male;

1984
Co-carcinogenic effect of chrysotile and amosite asbestos with benzo(a)pyrene in the lung of hamsters.
    Acta pathologica japonica, 1993, Volume: 43, Issue:4

    Topics: Adenoma; Animals; Asbestos; Asbestos, Amosite; Asbestos, Serpentine; Benzo(a)pyrene; Carcinogenicity

1993
Tumor-initiating activity and carcinogenicity of dibenzo[a,l]pyrene versus 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene at low doses in mouse skin.
    Carcinogenesis, 1993, Volume: 14, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Carci

1993
A comparison of the tumors induced by coal tar and benzo[a]pyrene in a 2-year bioassay.
    Carcinogenesis, 1998, Volume: 19, Issue:1

    Topics: Adenoma; Animals; Benzo(a)pyrene; Biological Assay; Carcinoma; Coal Tar; Diet; Female; Industrial Wa

1998
Pleomorphic (giant and/or spindle cell) carcinoma of lung shows a high percentage of variant CYP1A12.
    Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology, 2001, Volume: 6, Issue:2

    Topics: Alleles; Benzo(a)pyrene; Carcinogens; Carcinoma; Carcinoma, Giant Cell; Cytochrome P-450 CYP1A1; Exo

2001
Elevated levels of high-mobility-group chromosomal proteins, HMGA1, in murine skin carcinoma.
    Cancer letters, 2001, Nov-08, Volume: 173, Issue:1

    Topics: Acetic Acid; Animals; Benzo(a)pyrene; Biomarkers, Tumor; Blotting, Western; Carcinoma; Chromatograph

2001
A permanent fish cell line (EPC) for genotoxicity testing of marine sediments with the comet assay.
    Mutation research, 2001, Nov-15, Volume: 498, Issue:1-2

    Topics: Animals; Benzo(a)pyrene; Biological Assay; Carcinoma; Carps; Cell Survival; Comet Assay; Dose-Respon

2001
RNA relocation and persistence of nucleolus-like bodies at mitosis in benzo[a]pyrene-transformed human breast epithelial cells after microcell-mediated transfer of chromosomes 11 and 17.
    Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology, 2001, Volume: 23, Issue:3-4

    Topics: Benzo(a)pyrene; Breast Neoplasms; Carcinoma; Cell Line, Transformed; Cell Nucleolus; Chromosomes, Hu

2001
Identification and immunochemical characterization of IgA in sera of patients with mammary tumors.
    International journal of cancer, 1992, Feb-01, Volume: 50, Issue:3

    Topics: Age Factors; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Antibody Affinity; Antibody Specifi

1992
Visualization of a protein involved in seric immune complexes of patients with epithelial tumors having elevated levels of anti-'benzo[a]pyrene-like' IgA.
    Cancer letters, 1991, Dec-01, Volume: 60, Issue:3

    Topics: Antibodies, Monoclonal; Antigen-Antibody Complex; Autoantibodies; Benzo(a)pyrene; Biomarkers, Tumor;

1991
Transplacental induction of a specific mutation in fetal Ha-ras and its critical role in post-natal carcinogenesis.
    International journal of cancer, 1987, Dec-15, Volume: 40, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinoma; Cocarcinogenesis; DNA, Neoplas

1987
Benzo(a)pyrene:DNA adduct formation in normal human mammary epithelial cell cultures and the human mammary carcinoma T47D cell line.
    Cancer research, 1986, Volume: 46, Issue:6

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benzo(a)pyrene; Benzopyrenes; Breast; Breast Neo

1986
Presence of benz(a)pyrene in soil, room dust & in water samples of Azarbaijan Province of Iran & the carcinogenic activity on back skin of NMRI mice.
    Indian journal of cancer, 1987, Volume: 24, Issue:1

    Topics: Animals; Benzo(a)pyrene; Carcinoma; Dust; Environmental Pollutants; Housing; Iran; Mice; Mice, Inbre

1987
Influence of housing conditions for mice on the results of a dermal oncogenicity bioassay.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1986, Volume: 7, Issue:4

    Topics: Animals; Benzo(a)pyrene; Body Weight; Carcinoma; Dental Cements; Male; Mice; Mice, Inbred C3H; Papil

1986