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benzo(a)pyrene and Cancer of Skin

benzo(a)pyrene has been researched along with Cancer of Skin in 199 studies

Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.

Research Excerpts

ExcerptRelevanceReference
"55 mumol) with the dose-response relationship indicating a saturation of tumor multiplicity at approximately 7 tumors/animal."5.27Dose-response relationships of the tumorigenicity of cyclopenta[cd]pyrene, benzo[a]pyrene and 6-nitrochrysene in a newborn mouse lung adenoma bioassay. ( Busby, WF; Cornelisse, J; Kellenbach, ER; Lugtenburg, J; Stevens, EK, 1988)
" Here, we present our results on the expression of HMGA1 in murine skin carcinoma as detected by acid-urea electrophoresis, reverse-phase high-performance liquid chromatography and Western blot."3.71Elevated levels of high-mobility-group chromosomal proteins, HMGA1, in murine skin carcinoma. ( Jain, A; Rajeswari, MR; Ray, R; Singh, D, 2001)
" Application of rosemary to mouse skin also inhibited TPA-induced ornithine decarboxylase activity, TPA-induced inflammation, arachidonic acid-induced inflammation, TPA-induced hyperplasia, and TPA-induced tumor promotion."3.69Inhibition of skin tumorigenesis by rosemary and its constituents carnosol and ursolic acid. ( Conney, AH; Ferraro, T; Georgiadis, C; Ho, CT; Huang, MT; Laskin, JD; Lou, YR; Ma, W; Stauber, K; Wang, ZY, 1994)
"A combination of antioxidants-anticarcinogens, consisting of vitamins C and E, selenium and 2-mercaptopropionyl glycine (2-MPG), was administered orally for the prevention (PRG) and treatment (TRG) of benzo(a)pyrene (BaP)-induced malignant tumors (leiomyosarcomas), in Wistar rats."3.69Dose-related preventive and therapeutic effects of antioxidants-anticarcinogens on experimentally induced malignant tumors in Wistar rats. ( Evangelou, A; Kallistratos, G; Kalpouzos, G; Karkabounas, S; Liasko, R; Nonni, A; Stefanou, D, 1997)
"A number of bladder cancer case-control studies have noted an association with work as a machinist."2.40Oils and cancer. ( Tolbert, PE, 1997)
"Non-melanoma skin cancer (NMSC) is the most common cancer in the world."1.91The environmental carcinogen benzo[a]pyrene regulates epigenetic reprogramming and metabolic rewiring in a two-stage mouse skin carcinogenesis model. ( Chou, P; Dina Kuo, HC; Kong, AN; Mary Peter, R; Ramirez, CN; Sargsyan, D; Sarwar, MS; Shannar, A; Su, X; Wang, Y; Wu, R; Yang, Y; Yin, R, 2023)
"Excess skin cancer risks and hazard quotients for neurobehavioral effects calculated with the daily dose of total PAHs from the combined diaper core and top sheet averaged 1."1.72Health Risk Assessment of Dermal Exposure to Polycyclic Aromatic Hydrocarbons from the Use of Infant Diapers. ( Bernard, A; Dudler, V, 2022)
"Skin cancer is increasing at an alarming rate and becoming resistant to conventional chemotherapy necessitating improved drug delivery system."1.39Efficacy of PLGA-loaded apigenin nanoparticles in Benzo[a]pyrene and ultraviolet-B induced skin cancer of mice: mitochondria mediated apoptotic signalling cascades. ( Das, J; Das, S; Khuda-Bukhsh, AR; Paul, A; Samadder, A, 2013)
"An extension of this work resulted in a skin cancer slope factor derived on a per unit skin surface area basis of 3."1.37Development and application of a skin cancer slope factor for exposures to benzo[a]pyrene in soil. ( Campbell, J; Knafla, A; Petrovic, S; Richardson, M; Rowat, C, 2011)
"In the skin cancer tests, each substance was applied twice weekly for 104 weeks to the clipped backs of groups of 50 male C3H mice."1.37Paving asphalt products exhibit a lack of carcinogenic and mutagenic activity. ( Daughtrey, WC; Freeman, JJ; Goyak, KO; McGowan, C; McKee, RH; Minsavage, GD, 2011)
"Using skin cancer model, we demonstrated that high levels of HMGB directly correlate with the extent of neoplastic changes, and it appears that HMGB is an effective stimulus for cell differentiation, tumor progression, and metastatic invasion."1.35Overexpression of high mobility group (HMG) B1 and B2 proteins directly correlates with the progression of squamous cell carcinoma in skin. ( Rajeswari, MR; Ray, R; Sharma, A, 2008)
"Melatonin 20 mg/l was followed by shorter survival after tumor development whereas 2 mg/l produced the opposite effect."1.34[Melatonin suppresses benz(a)pyrene-induced carcinogenesis in mice]. ( Anisimov, VN; Plotnikova, NA; Vesnushkin, GM, 2007)
"Imperatorin was an effective inhibitor of skin tumor initiation by DMBA and also inhibited complete carcinogenesis by this PAH."1.30Effect of naturally occurring coumarins on the formation of epidermal DNA adducts and skin tumors induced by benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in SENCAR mice. ( Bostic, S; Cai, Y; DiGiovanni, J; Dubowski, A; Ivie, W; Johnston, D; Kleiner, H, 1997)
" Dose-response studies were conducted at low doses in mouse skin by initiation-promotion and repeated application to compare its activity to that of 7,12-dimethylbenz[a]anthracene (DMBA), benzo[a]pyrene (B[a]P), DB[a,l]P-8,9-dihydrodiol and DB[a,l]P-11,12-dihydrodiol."1.29Tumor-initiating activity and carcinogenicity of dibenzo[a,l]pyrene versus 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene at low doses in mouse skin. ( Cavalieri, EL; Higginbotham, S; Johansson, SL; RamaKrishna, NV; Rogan, EG, 1993)
"None of the mutations found only in metastases were located in exon 8."1.29Lack of concordant p53 mutations in some paired primary and metastatic mouse squamous cell carcinomas induced by chemical carcinogenesis. ( Bauer, B; Goodrow, TL; Klein-Szanto, AJ; Mitsunaga, S; Zhang, SY, 1995)
"Acetone-, TPA- or BaP-treated animals were used as negative and positive controls, respectively."1.28Comparative tumor-initiating ability of 7H-dibenzo(c,g)carbazole and dibenz(a,j)acridine in mouse skin. ( Andringa, A; Barkley, W; LaDow, K; Miller, ML; Warshawsky, D, 1992)
"Indomethacin was found to delay the onset and reduce the size of tumours in BP- but not DMBA-treated mice."1.28A role for prostaglandins in the suppression of cutaneous cellular immunity and tumour development in benzo(a)pyrene- but not dimethylbenz(a)anthracene-treated mice. ( Andrews, J; Halliday, GM; Muller, HK, 1991)
" The substantial cell killing and regenerative proliferation, and the correspondence between the dose-response patterns for epidermal damage and tumors, together with the initial appearance of tumors in the benign form, a characteristic of the action of promoting agents, provided evidence that the tissue damage associated with the high dose levels of B[a]P used in this study reflected tumor-promoting activity in this mouse epidermal tumorigenesis model."1.28Benzo[a]pyrene-induced skin damage and tumor promotion in the mouse. ( Albert, RE; Andringa, A; Baxter, CS; Cody, T; Miller, ML; Shukla, R, 1991)
" Parallelism of dose-response curves of different materials and quantitative reproducibility of dermal carcinogenesis data were also examined."1.28Estimation of epidermal carcinogenic potency. ( Lewis, SC; McKee, RH; Nicolich, MJ; Scala, RA, 1990)
"Clotrimazole was also found to be a potent inhibitor of epoxide hydrolase activity in vitro with a 50% inhibition at 0."1.27Clotrimazole, an inhibitor of epidermal benzo(a)pyrene metabolism and DNA binding and carcinogenicity of the hydrocarbon. ( Bickers, DR; Cherniack, AD; Cherniack, EP; Das, M; Del Tito, BJ; Mukhtar, H, 1984)
" The tumor-initiating activity of B(a)P, its covalent binding to mouse epidermal DNA, and the formation of the major hydrocarbon/deoxyribonucleoside adduct showed approximately parallel dose-response curves."1.27Formation of benzo(a)pyrene/DNA adducts and their relationship to tumor initiation in mouse epidermis. ( Ashurst, SW; Cohen, GM; DiGiovanni, J; Nesnow, S; Slaga, TJ, 1983)
"Ellagic acid was the most potent antagonist of tumorigenesis since this compound is active, by i."1.27Protective effects of ellagic acid and other plant phenols on benzo[a]pyrene-induced neoplasia in mice. ( Lesca, P, 1983)
" The probit and Weibull analysis of the results showed a linear dose-response relationship for both tumor incidences and tumor induction times."1.27Investigation on the carcinogenicity of emission condensate from brown coal-fired residential furnaces applied to mouse skin. ( Brune, H; Dettbarn, G; Deutsch-Wenzel, RP; Grimmer, G; Misfeld, J; Timm, J, 1984)
" BP dose-response studies showed that, in cells of different maturation states, BP-DNA adduct levels were similar."1.27Benzo(a)pyrene-DNA adduct formation and removal in mouse epidermis in vivo and in vitro: relationship of DNA binding to initiation of skin carcinogenesis. ( Nakayama, J; Poirier, MC; Yuspa, SH, 1984)
" These results correlated closely with the dose-response relationships for tumor initiation by the two hydrocarbons."1.27Correlation between formation of a specific hydrocarbon-deoxyribonucleoside adduct and tumor-initiating activity of 7,12-dimethylbenz(a)anthracene and its 9- and 10-monofluoroderivatives in mice. ( DiGiovanni, J; Fisher, EP; Sawyer, TW, 1986)
" Analyses of dose-response curves suggest (i) CuDIPS preferentially inhibits BP mutagenesis; (ii) the antimutagenic activity of CuDIPS towards DMBA and the cytotoxicity of the copper complex are derived from the DIPS component of the chelate; (iii) the antimutagenic activity of CuDIPS towards BP requires both copper and DIPS; and (iv) DIPS and CuDIPS induced cytotoxicity is required for inhibition of mutagenesis."1.27Survey of cytotoxicities and antimutagenic and antitumor initiating activities of Cu(II)(3,5-diisopropylsalicylate)2 and its analogs in a keratinocyte-mediated mutation assay and the murine skin multistage carcinogenesis model. ( Colby, AB; Reiners, JJ, 1988)
"55 mumol) with the dose-response relationship indicating a saturation of tumor multiplicity at approximately 7 tumors/animal."1.27Dose-response relationships of the tumorigenicity of cyclopenta[cd]pyrene, benzo[a]pyrene and 6-nitrochrysene in a newborn mouse lung adenoma bioassay. ( Busby, WF; Cornelisse, J; Kellenbach, ER; Lugtenburg, J; Stevens, EK, 1988)
"Ellagic acid was found to be an effective inhibitor of tumor formation whether the tumor data are considered as percent mice with tumors, cumulative number of tumors, tumors per mouse or tumors per tumor bearing animal as a function of the number of weeks on test."1.27Protection against 3-methylcholanthrene-induced skin tumorigenesis in Balb/C mice by ellagic acid. ( Bickers, DR; Das, M; Del Tito, BJ; Mukhtar, H, 1984)
"Skin cancer has long been associated with industrial and environmental exposure to individual chemical compounds, complex chemical mixtures, X-irradiation and UV-irradiation."1.27Periodic response difference in mouse epidermis chronically exposed to crude-oils or BaP: males vs. females. ( Holland, LM; Wilson, JS, 1988)
" Similarly, the topical application of 2,500 nmol of ellagic acid at 2 h, 1 h and 5 min before and at 10 min after the application of 2 nmol of [3H]B[a]P did not inhibit the formation of DNA-bound adducts, but the same dosing regimen of 3-O-decylellagic acid (total dose of 10,000 nmol) resulted in a modest inhibition in the formation of DNA-bound adducts."1.27Effect of ellagic acid and 3-O-decylellagic acid on the formation of benzo[a]pyrene-derived DNA adducts in vivo and on the tumorigenicity of 3-methylcholanthrene in mice. ( Chang, RL; Conney, AH; Huang, MT; Jerina, DM; Sayer, JM; Smart, RC; Wood, AW, 1986)
" Dose-response relationships were obtained for NMU and NC as well as for BaP."1.27Local application to mouse skin as a carcinogen specific test system for non-volatile nitroso compounds. ( Brune, H; Deutsch-Wenzel, RP; Grimmer, G; Misfeld, J, 1985)
"Incidence of tumors (predominantly squamous carcinomas) and mortality was 100% by 36 weeks in all environments in the high-dose group."1.26Effect of temperature on benzo[a]pyrene-induced hyperplastic and neoplastic skin lesions in mice. ( Weisbrode, SE; Weiss, HS, 1981)
" This reverse dose-response may be due to the relatively high cytotoxicity of CPEP, BP, which was compared to CPEP at the low dose, elicited tumors in 100% of the mice."1.26Carcinogenicity of the environmental pollutants cyclopenteno-[cd]pyrene and cyclopentano[cd]pyrene in mouse skin. ( Cavalieri, E; Munhall, A; Rogan, E; Toth, B, 1981)
"Development and growth of skin cancer may be affected by various physical and chemical factors present in human environment."1.26Acceleration of the development of benzopyrene-induced skin cancer in mice by microwave radiation. ( Janiak, M; Kałczak, M; Pietraszek, A; Szmigielski, S; Szudziński, A; Wrembel, J, 1982)

Research

Studies (199)

TimeframeStudies, this research(%)All Research%
pre-199091 (45.73)18.7374
1990's61 (30.65)18.2507
2000's33 (16.58)29.6817
2010's11 (5.53)24.3611
2020's3 (1.51)2.80

Authors

AuthorsStudies
Bernard, A3
Dudler, V3
Sarwar, MS1
Ramirez, CN1
Dina Kuo, HC1
Chou, P1
Wu, R1
Sargsyan, D1
Yang, Y1
Shannar, A1
Mary Peter, R1
Yin, R1
Wang, Y3
Su, X1
Kong, AN1
Magee, BH1
Forsberg, ND1
Das, S1
Das, J1
Samadder, A1
Paul, A1
Khuda-Bukhsh, AR1
Singh, P1
Arora, D1
Shukla, Y5
Sharma, A3
Ray, R3
Rajeswari, MR4
Fingerle-Rowson, G1
Kaleswarapu, DR1
Schlander, C1
Kabgani, N1
Brocks, T1
Reinart, N1
Busch, R1
Schütz, A1
Lue, H1
Du, X1
Liu, A1
Xiong, H1
Chen, Y1
Nemajerova, A1
Hallek, M1
Bernhagen, J1
Leng, L1
Bucala, R1
Ramanjaneyulu, A1
Nigam, N1
George, J1
Srivastava, S1
Roy, P1
Bhui, K1
Singh, M1
Shi, S1
Yoon, DY1
Hodge-Bell, KC1
Bebenek, IG1
Whitekus, MJ1
Zhang, R1
Cochran, AJ1
Huerta-Yepez, S1
Yim, SH1
Gonzalez, FJ1
Jaiswal, AK6
Hankinson, O1
Singh, B1
Kale, RK1
Shen, J1
Barrios, RJ1
Knafla, A2
Petrovic, S2
Richardson, M2
Campbell, J1
Rowat, C1
Patrick, BA1
Gong, X1
Clark, CR1
Burnett, DM1
Parker, CM1
Arp, EW1
Swanson, MS1
Minsavage, GD2
Kriech, AJ1
Osborn, LV1
Freeman, JJ2
Barter, RA1
Newton, PE1
Beazley, SL1
Stewart, CW1
Goyak, KO1
McKee, RH2
McGowan, C1
Daughtrey, WC1
Bassi, DE1
Klein-Szanto, AJ7
Man'cheva, TA1
Demidov, DV1
Plotnikova, NA2
Kharitonova, TV1
Pashkevich, IV1
Anisimov, VN3
Siddens, LK1
Larkin, A1
Krueger, SK1
Bradfield, CA1
Waters, KM1
Tilton, SC1
Pereira, CB1
Löhr, CV1
Arlt, VM2
Phillips, DH3
Williams, DE1
Baird, WM5
Lesca, P2
Perrot, N1
Peryt, B1
Anikin, IV1
Kozlov, AP1
Popov, AV1
Zabezhinskiĭ, MA1
Tyndyk, ML1
Uleckiene, S1
Domkiene, V1
Lee, BM2
Kim, HS2
Kim, IS1
Ahn, MY1
Chun, SA1
Yoo, SD1
Park, YA1
Choi, SM1
Kim, KB1
Han, SY1
Park, KL1
Kwack, SJ1
Song, HS1
Lee, KR1
Bae, HJ1
Cho, MH1
MUZIK, F2
PRODI, G1
MALTONI, C1
Jain, A2
Singh, D2
Jagannathan, NR1
Sharma, U1
Degaonkar, MN1
Degonkar, MN1
MILLER, JF1
GRANT, GA1
ROE, FJ1
ARGUS, MF1
ARCOS, JC1
JACQUIER, A1
DAUDEL, P1
Dasgupta, T3
Rao, AR4
Yadava, PK2
Banerjee, S1
Pinkney, AE1
Harshbarger, JC1
May, EB1
Reichert, WL1
Iskander, K2
Paquet, M2
Brayton, C2
Gaikwad, A1
Long, DJ2
Barrios, R1
Gao, D1
Atencio, DP1
Perez, E1
Saladi, R1
Moore, J1
Guevara, D1
Rosenstein, BS1
Lebwohl, M1
Wei, H1
Zhang, Z1
Yao, R1
Li, J1
Boone, CW1
Lubet, RA1
You, M1
Phillipps, KA1
Brecher, RW1
Lee, YJ1
Kao, ES1
Chu, CY2
Lin, WL2
Chiou, YH1
Tseng, TH3
Courter, LA2
Musafia-Jeknic, T2
Fischer, K2
Bildfell, R2
Giovanini, J1
Pereira, C2
Vesnushkin, GM1
Hosoya, T1
Harada, N1
Mimura, J2
Motohashi, H1
Takahashi, S1
Nakajima, O1
Morita, M1
Kawauchi, S1
Yamamoto, M1
Fujii-Kuriyama, Y2
Luch, A1
Poirier, MC2
Mukhtar, H8
Del Tito, BJ2
Das, M7
Cherniack, EP1
Cherniack, AD1
Bickers, DR7
Nesnow, S6
Evans, C1
Stead, A1
Creason, J1
Slaga, TJ12
Triplett, LL2
Depass, LR2
Chen, KC1
Peterson, LG1
Santamaria, L3
Bianchi, A3
Arnaboldi, A3
Andreoni, L3
Weisbrode, SE1
Weiss, HS4
Logani, MK1
Austin, WA1
Davies, RE1
DiGiovanni, J11
Boutwell, RK3
Cavalieri, E5
Rogan, E5
Toth, B1
Munhall, A2
Ashurst, SW2
Cohen, GM2
Rymer, J1
Verma, AK1
Conrad, EA1
Buhler, DR2
Unlu, F1
Thakker, DR1
Newman, MS1
Levin, W2
Conney, AH8
Jerina, DM6
Ianysheva, NIa1
Voloshchenko, OI1
Chernichenko, IA1
Balenko, NV1
El-Bayoumy, K1
Hecht, SS3
Hoffmann, D3
Shugart, L1
Holland, JM1
Rahn, RO1
Szudziński, A1
Pietraszek, A1
Janiak, M1
Wrembel, J1
Kałczak, M1
Szmigielski, S1
Burns, FJ2
Albert, RE4
Salmasi, S4
Patil, K1
Lewis, SC3
Reiners, J1
Davidson, K1
Nelson, K1
Mamrack, M1
Slaga, T1
Mahlum, DD3
Buening, MK1
Wood, AW3
Chang, RL5
Agranat, I1
Rabinovitz, M1
Mah, HD1
Hernandez, O1
Simpson, RB1
Miller, EC1
Miller, JA2
O'Connell, JF2
Pitt, JF1
Miller, RE1
Graff, DE1
Bermond, P2
Gradiski, D1
Vinot, J1
Zissu, D1
Limasset, JC1
Lafontaine, M1
Gensler, H1
Bowden, GT1
Reiners, JJ3
Pashin, IuV2
Bakhitova, LM2
Kirso, UE2
Kiung, AI2
LaVoie, EJ2
Shigematsu, A1
Adams, EA1
Rigotty, J2
Pera, MF1
Gorman, PA1
Nakayama, J3
Yuspa, SH1
Deutsch-Wenzel, RP2
Brune, H2
Grimmer, G2
Dettbarn, G1
Misfeld, J2
Timm, J1
Pinsky, C1
Bose, R1
Mitsunaga, SI1
Zhang, SY5
Ruggeri, BA2
Gimenez-Conti, I1
Robles, AI1
Conti, CJ1
Bauer, B4
Mitsunaga, S2
Goodrow, TL1
Lawrence, JN1
Benford, DJ1
Wunderlich, V1
Rajewsky, MF1
Wang, CJ3
Lee, MJ3
Chang, MC2
Lin, JK1
Vienneau, DS1
DeBoni, U1
Wells, PG1
Warshawsky, D5
Barkley, W5
Miller, ML5
LaDow, K2
Andringa, A3
Shertzer, HG1
Sainsbury, M1
Reilman, R1
Mellert, W1
Kühborth, B1
Gembardt, C1
Munk, R1
Urabe, A2
Terao, H2
Moon, DC2
Hori, Y2
Kinoshita, N2
Lin, JM1
Amin, S1
Trushin, N1
Alldrick, AJ1
Jiang, H2
Yamamoto, S2
Kato, R2
Gold, A1
Sangaiah, R1
Colapietro, AM1
Goodell, AL1
Smart, RC2
Sherman, JH1
Baxter, CS2
Beltrán, L1
Rupp, A1
Harvey, RG2
Gill, RD1
Huang, MT6
Ho, CT2
Wang, ZY4
Ferraro, T2
Lou, YR3
Stauber, K1
Ma, W1
Georgiadis, C1
Laskin, JD3
He, ZM1
Meegalla, RL1
Weyand, EH1
Ruggeri, B1
DiRado, M1
Goodrow, T2
Pavone, A1
Maldve, R1
Fischer, SM2
Higginbotham, S4
RamaKrishna, NV2
Johansson, SL1
Rogan, EG2
Cavalieri, EL2
Bingham, E1
Park, KK1
Surh, YJ2
Ramesh, G2
Das, UN2
Köpf-Maier, P1
Flug, M1
Ozawa, S1
Shimada, M1
Yamazoe, Y1
Saran, A1
Bouthillier, Y1
Pioli, C1
Mouton, D1
Covelli, V1
Doria, G1
Neveu, T1
Biozzi, G1
Evangelou, A1
Kalpouzos, G1
Karkabounas, S1
Liasko, R1
Nonni, A1
Stefanou, D1
Kallistratos, G1
Liu, SC1
Morris, R1
O'Brien, TG1
Megosh, LC1
Gilliard, G1
Soler, AP1
Cai, Y1
Kleiner, H1
Johnston, D1
Dubowski, A1
Bostic, S1
Ivie, W1
Tolbert, PE1
Pfeifer, GP1
Denissenko, MF1
Clapper, M1
Litwin, S1
Watts, P1
Horikawa, K1
Sera, N1
Murakami, K1
Sano, N1
Izumi, K1
Tokiwa, H1
Hsu, JD1
Hsu, CL1
Lan, KP1
Singh, A2
Kim, SG1
Liem, A1
Lee, JW1
Wei, SJ2
Merkler, KA1
Gwynne, M1
Cui, XX2
Murthy, B1
Xie, JG1
Lu, YP1
Tsai, YY1
Hwang, JM1
Shimizu, Y1
Nakatsuru, Y1
Ichinose, M1
Takahashi, Y1
Kume, H1
Ishikawa, T1
van Steeg, H1
Mullenders, LH1
Vijg, J1
Jeohn, GH1
Waikel, RL1
Wang, XJ1
Perlaky, L1
Roop, DR1
Chen, XG1
Li, Y1
Yan, CH1
Li, LN1
Han, R1
Arora, A1
Shamberger, RJ1
Martin, KR1
Trempus, C1
Saulnier, M1
Kari, FW1
Barrett, JC1
French, JE1
Goldstein, LS1
Schiltz, M1
Yagi, H2
Banejee, S1
Yadav, PK1
Kurian, P1
Milo, GE1
Noyes, I1
Georgiadis, CA1
Antony, M2
Mehrotra, NK2
Azuine, MA1
Bhide, SV1
Finnegan-Olive, T1
Mitchell, JM1
Newmark, H1
Yang, CS1
Lasne, C2
Nguyen-Ba, G1
Oueslatti, R1
Chouroulinkov, I2
Alworth, WL1
Viaje, A1
Sandoval, A1
Warren, BS1
Andrews, J1
Halliday, GM2
Muller, HK2
Athas, WF1
Hedayati, MA1
Matanoski, GM1
Farmer, ER1
Grossman, L1
Devanesan, PD1
Todorovic, R1
Cody, TE1
Shukla, R2
Cody, T1
Marnett, LJ1
Reddy, A1
Pruess-Schwartz, D1
Ji, C1
Nicolich, MJ1
Scala, RA1
Klann, RC1
Fitzgerald, DJ1
Piccoli, C1
Yamasaki, H2
Springer, DL2
Mann, DB1
Dankovic, DA1
Thomas, BL1
Wright, CW1
Ruby, JC1
Athar, M1
Khan, WA2
Melikian, AA1
Jordan, KG1
Braley, J1
Meschter, CL1
Hollstein, M1
Martel, N1
Cabral, JR1
Galendo, D1
Tomatis, L1
Don, PS1
Berger, NA1
Hakaim, AG1
Jacoby, WT2
Sawyer, TW2
Fisher, EP3
Asokan, P1
Santella, RM1
Smolarek, TA1
Venegas, W1
Royer, R1
Chang, K1
Naito, M1
Naito, Y1
Bik, DP1
Colby, AB1
Ravetto, C1
Bianchi, L1
Pizzala, R1
Santagati, G1
Kosoĭ, GKh1
Parfenov, IuD2
Turusov, VS2
Gensler, HL1
Cremonesi, P2
Busby, WF1
Stevens, EK1
Kellenbach, ER1
Cornelisse, J1
Lugtenburg, J1
Sadhana, AS1
Kucheria, K1
Bijani, V1
Wilson, JS1
Holland, LM1
Kumar, S1
Upadhyay, RR1
Ghanayat, P1
Benbehani, AN1
Sanayen, HD1
Witschi, HP1
Smith, LH1
Frome, EL1
Pequet-Goad, ME1
Griest, WH1
Ho, CH1
Guerin, MR1
Kosoĭ, KKh1
Morris, RJ1
Van Cantfort, J1
Lorand, T1
Gielen, JE1
Lapière, CM1
Sayer, JM2
Bergman, H1
Sebti, SM1
Reinsvold, LA1
Carlson, GP1
Fossa, AA1
Morse, MA1
Weaver, PM1
Weil, CS1
Ballantyne, B1
Losco, PE1
Reid, JB1
Simon, GS1
Decina, PC1
Prichett, WP1
Aalfs, KK1
Wong, CQ1
Newmark, HL1
Reilly, CA1
Peraino, C1
Haugen, DA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Oral Supplementation With Curcumin on Insulin Sensitivity in Subjects With Prediabetes[NCT03917784]Phase 4142 participants (Anticipated)Interventional2019-02-25Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for benzo(a)pyrene and Cancer of Skin

ArticleYear
Testing the validity of a proposed dermal cancer slope factor for Benzo[a]pyrene.
    Regulatory toxicology and pharmacology : RTP, 2021, Volume: 120

    Topics: Benzo(a)pyrene; Environmental Monitoring; Humans; Reproducibility of Results; Risk Assessment; Skin;

2021
Development of a dermal cancer slope factor for benzo[a]pyrene.
    Regulatory toxicology and pharmacology : RTP, 2006, Volume: 45, Issue:2

    Topics: Administration, Cutaneous; Animals; Benzo(a)pyrene; Carcinogens, Environmental; Dose-Response Relati

2006
Oils and cancer.
    Cancer causes & control : CCC, 1997, Volume: 8, Issue:3

    Topics: 2-Naphthylamine; Benzo(a)pyrene; Carcinogens; Chlorine Compounds; Esophageal Neoplasms; Ethanolamine

1997
Formation and repair of DNA lesions in the p53 gene: relation to cancer mutations?
    Environmental and molecular mutagenesis, 1998, Volume: 31, Issue:3

    Topics: 5-Methylcytosine; Animals; Benzo(a)pyrene; Breast Neoplasms; Carcinogens, Environmental; Colonic Neo

1998
Dose-dependent differences in the profile of mutations induced by carcinogenic (R,S,S,R) bay- and fjord-region diol epoxides of polycyclic aromatic hydrocarbons.
    Advances in experimental medicine and biology, 2001, Volume: 500

    Topics: Acridines; Amino Acid Substitution; Animals; Base Sequence; Bay-Region, Polycyclic Aromatic Hydrocar

2001
Modification of multistage skin carcinogenesis in mice.
    Progress in experimental tumor research, 1991, Volume: 33

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Cocarcinogenesis; Disease Models, Animal;

1991

Trials

1 trial available for benzo(a)pyrene and Cancer of Skin

ArticleYear
Retardation of benzo[a]pyrene-induced epidermal tumor formation by the potent antioxidant 4b,5,9b,10-tetrahydroindeno[1,2-b]indole.
    Cancer letters, 1994, Nov-11, Volume: 86, Issue:2

    Topics: Administration, Topical; Animals; Antioxidants; Benzo(a)pyrene; Carcinogenicity Tests; Female; Indol

1994

Other Studies

192 other studies available for benzo(a)pyrene and Cancer of Skin

ArticleYear
Health Risk Assessment of Dermal Exposure to Polycyclic Aromatic Hydrocarbons from the Use of Infant Diapers.
    International journal of environmental research and public health, 2022, 11-10, Volume: 19, Issue:22

    Topics: Benzo(a)pyrene; Diapers, Infant; Female; Humans; Infant; Polycyclic Aromatic Hydrocarbons; Risk Asse

2022
Health Risk Assessment of Dermal Exposure to Polycyclic Aromatic Hydrocarbons from the Use of Infant Diapers.
    International journal of environmental research and public health, 2022, 11-10, Volume: 19, Issue:22

    Topics: Benzo(a)pyrene; Diapers, Infant; Female; Humans; Infant; Polycyclic Aromatic Hydrocarbons; Risk Asse

2022
Health Risk Assessment of Dermal Exposure to Polycyclic Aromatic Hydrocarbons from the Use of Infant Diapers.
    International journal of environmental research and public health, 2022, 11-10, Volume: 19, Issue:22

    Topics: Benzo(a)pyrene; Diapers, Infant; Female; Humans; Infant; Polycyclic Aromatic Hydrocarbons; Risk Asse

2022
Health Risk Assessment of Dermal Exposure to Polycyclic Aromatic Hydrocarbons from the Use of Infant Diapers.
    International journal of environmental research and public health, 2022, 11-10, Volume: 19, Issue:22

    Topics: Benzo(a)pyrene; Diapers, Infant; Female; Humans; Infant; Polycyclic Aromatic Hydrocarbons; Risk Asse

2022
Health Risk Assessment of Dermal Exposure to Polycyclic Aromatic Hydrocarbons from the Use of Infant Diapers.
    International journal of environmental research and public health, 2022, 11-10, Volume: 19, Issue:22

    Topics: Benzo(a)pyrene; Diapers, Infant; Female; Humans; Infant; Polycyclic Aromatic Hydrocarbons; Risk Asse

2022
Health Risk Assessment of Dermal Exposure to Polycyclic Aromatic Hydrocarbons from the Use of Infant Diapers.
    International journal of environmental research and public health, 2022, 11-10, Volume: 19, Issue:22

    Topics: Benzo(a)pyrene; Diapers, Infant; Female; Humans; Infant; Polycyclic Aromatic Hydrocarbons; Risk Asse

2022
Health Risk Assessment of Dermal Exposure to Polycyclic Aromatic Hydrocarbons from the Use of Infant Diapers.
    International journal of environmental research and public health, 2022, 11-10, Volume: 19, Issue:22

    Topics: Benzo(a)pyrene; Diapers, Infant; Female; Humans; Infant; Polycyclic Aromatic Hydrocarbons; Risk Asse

2022
Health Risk Assessment of Dermal Exposure to Polycyclic Aromatic Hydrocarbons from the Use of Infant Diapers.
    International journal of environmental research and public health, 2022, 11-10, Volume: 19, Issue:22

    Topics: Benzo(a)pyrene; Diapers, Infant; Female; Humans; Infant; Polycyclic Aromatic Hydrocarbons; Risk Asse

2022
Health Risk Assessment of Dermal Exposure to Polycyclic Aromatic Hydrocarbons from the Use of Infant Diapers.
    International journal of environmental research and public health, 2022, 11-10, Volume: 19, Issue:22

    Topics: Benzo(a)pyrene; Diapers, Infant; Female; Humans; Infant; Polycyclic Aromatic Hydrocarbons; Risk Asse

2022
The environmental carcinogen benzo[a]pyrene regulates epigenetic reprogramming and metabolic rewiring in a two-stage mouse skin carcinogenesis model.
    Carcinogenesis, 2023, 08-10, Volume: 44, Issue:5

    Topics: Animals; Benzo(a)pyrene; Carcinogenesis; Carcinogens, Environmental; Epigenesis, Genetic; Melatonin;

2023
Efficacy of PLGA-loaded apigenin nanoparticles in Benzo[a]pyrene and ultraviolet-B induced skin cancer of mice: mitochondria mediated apoptotic signalling cascades.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 62

    Topics: Animals; Anticarcinogenic Agents; Apigenin; Apoptosis; Benzo(a)pyrene; Drug Carriers; Lactic Acid; M

2013
Enhanced chemoprevention by the combined treatment of pterostilbene and lupeol in B[a]P-induced mouse skin tumorigenesis.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2017, Volume: 99

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Benzo(a)pyrene; Cell Cycle; Cell Transfo

2017
Overexpression of high mobility group (HMG) B1 and B2 proteins directly correlates with the progression of squamous cell carcinoma in skin.
    Cancer investigation, 2008, Volume: 26, Issue:8

    Topics: Animals; Benzo(a)pyrene; Carcinoma, Squamous Cell; Cell Differentiation; Disease Progression; DNA Re

2008
A tautomerase-null macrophage migration-inhibitory factor (MIF) gene knock-in mouse model reveals that protein interactions and not enzymatic activity mediate MIF-dependent growth regulation.
    Molecular and cellular biology, 2009, Volume: 29, Issue:7

    Topics: Alleles; Amino Acid Substitution; Animals; Benzo(a)pyrene; Cell Proliferation; Cell Transformation,

2009
Involvement of high mobility group B proteins in cisplatin-induced cytotoxicity in squamous cell carcinoma of skin.
    DNA and cell biology, 2009, Volume: 28, Issue:7

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzo(a)pyrene; Blotting, Western; Carcinoma, Squamous Ce

2009
Induction of apoptosis by [6]-gingerol associated with the modulation of p53 and involvement of mitochondrial signaling pathway in B[a]P-induced mouse skin tumorigenesis.
    Cancer chemotherapy and pharmacology, 2010, Volume: 65, Issue:4

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Benzo(a)pyrene; Blotting, Western; Caspases; Catecho

2010
The aryl hydrocarbon receptor nuclear translocator (Arnt) is required for tumor initiation by benzo[a]pyrene.
    Carcinogenesis, 2009, Volume: 30, Issue:11

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Aryl Hydrocarbon Receptor Nuclear Translocator; Benzo(a)pyre

2009
Chemomodulatory effect of Trachyspermum ammi on murine skin and forestomach papillomagenesis.
    Nutrition and cancer, 2010, Volume: 62, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antioxidants; Apiaceae; Benzo(a)

2010
Inactivation of the quinone oxidoreductases NQO1 and NQO2 strongly elevates the incidence and multiplicity of chemically induced skin tumors.
    Cancer research, 2010, Feb-01, Volume: 70, Issue:3

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Benz(a)Anthracenes; Benzo(a)pyrene; Blotting, Wester

2010
Development and application of a skin cancer slope factor for exposures to benzo[a]pyrene in soil.
    Regulatory toxicology and pharmacology : RTP, 2011, Volume: 59, Issue:1

    Topics: Administration, Cutaneous; Administration, Oral; Animals; Benzo(a)pyrene; Body Surface Area; Carcino

2011
Disruption of NAD(P)H:quinone oxidoreductase 1 gene in mice leads to 20S proteasomal degradation of p63 resulting in thinning of epithelium and chemical-induced skin cancer.
    Oncogene, 2011, Mar-03, Volume: 30, Issue:9

    Topics: Animals; Benzo(a)pyrene; Blotting, Western; Cell Differentiation; Epithelium; Fibroblasts; Immunopre

2011
Asphalt fume dermal carcinogenicity potential: I. dermal carcinogenicity evaluation of asphalt (bitumen) fume condensates.
    Regulatory toxicology and pharmacology : RTP, 2011, Volume: 61, Issue:1

    Topics: Administration, Cutaneous; Air Pollutants, Occupational; Animals; Benzo(a)pyrene; Carcinogenicity Te

2011
Paving asphalt products exhibit a lack of carcinogenic and mutagenic activity.
    International journal of toxicology, 2011, Volume: 30, Issue:5

    Topics: Animals; Benzo(a)pyrene; Carcinogens; Dimethyl Sulfoxide; Hydrocarbons; Male; Mice; Mice, Inbred C3H

2011
Carcinogen-induced animal models of head and neck squamous cell carcinoma.
    Current protocols in pharmacology, 2007, Volume: Chapter 14

    Topics: Animals; Benzo(a)pyrene; Carcinoma, Squamous Cell; Cricetinae; Disease Models, Animal; Female; Head

2007
Melatonin and metformin inhibit skin carcinogenesis and lipid peroxidation induced by benz(a)pyrene in female mice.
    Bulletin of experimental biology and medicine, 2011, Volume: 151, Issue:3

    Topics: Animals; Antioxidants; Benzo(a)pyrene; Cell Transformation, Neoplastic; Female; Lipid Peroxidation;

2011
Polycyclic aromatic hydrocarbons as skin carcinogens: comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse.
    Toxicology and applied pharmacology, 2012, Nov-01, Volume: 264, Issue:3

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens, Environmental; Gene Expression Regulation, Neopl

2012
Modulating effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on skin carcinogenesis initiated by the weak inducer 7,12-dimethylbenz(a)anthracene.
    Drug metabolism and drug interactions, 1994, Volume: 11, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Buffers; C

1994
[Susceptibility of wild and knockout p53 FVB/N line mice to benz(a)pyrene-induced subcutaneous sarcoma].
    Voprosy onkologii, 2002, Volume: 48, Issue:6

    Topics: Animals; Benzo(a)pyrene; Carcinogens; Fibrosarcoma; Genes, p53; Genetic Predisposition to Disease; H

2002
Investigation of ethyl alcohol and beta-carotene effect on two models of carcinogenesis.
    Acta biologica Hungarica, 2003, Volume: 54, Issue:1

    Topics: Animals; Benzo(a)pyrene; beta Carotene; Carcinogens; Ethanol; Liver; Lung Neoplasms; Mice; Mice, Inb

2003
Ras transgene expression in TG-AC mice treated with benzo[a]pyrene.
    Biological & pharmaceutical bulletin, 2003, Volume: 26, Issue:5

    Topics: Animals; Benzo(a)pyrene; Carcinogens; Carcinoma; Female; In Situ Hybridization; Mice; Mice, Transgen

2003
Influence of lanosterol and chicken embryonal extract upon the course of 3,4-benzpyrene induced skin carcinogenesis in mice.
    Ceskoslovenska onkologia, 1956, Volume: 3, Issue:4

    Topics: Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Carcinogenesis; Chickens; Embryo, Mammali

1956
Influence of lanosterol and chicken embryonal extract upon the course of 3,4-benzpyrene induced skin carcinogenesis in mice.
    Ceskoslovenska onkologia, 1956, Volume: 3, Issue:4

    Topics: Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Carcinogenesis; Chickens; Embryo, Mammali

1956
Influence of lanosterol and chicken embryonal extract upon the course of 3,4-benzpyrene induced skin carcinogenesis in mice.
    Ceskoslovenska onkologia, 1956, Volume: 3, Issue:4

    Topics: Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Carcinogenesis; Chickens; Embryo, Mammali

1956
Influence of lanosterol and chicken embryonal extract upon the course of 3,4-benzpyrene induced skin carcinogenesis in mice.
    Ceskoslovenska onkologia, 1956, Volume: 3, Issue:4

    Topics: Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Carcinogenesis; Chickens; Embryo, Mammali

1956
[Effect of ultraviolet rays on 9,10-dimethyl-1,2-benzanthracene- & 3,4-benzopyrene-induced skin carcinogenesis in the rat].
    Bollettino della Societa italiana di biologia sperimentale, 1959, Mar-31, Volume: 35, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyr

1959
Evaluation of skin tumors by magnetic resonance imaging.
    Laboratory investigation; a journal of technical methods and pathology, 2003, Volume: 83, Issue:9

    Topics: Animals; Benzo(a)pyrene; Carcinogens; Carcinoma, Squamous Cell; Disease Models, Animal; Female; Magn

2003
EFFECT OF THYMECTOMY ON THE INDUCTION OF SKIN TUMOURS BY 3,4-BENZOPYRENE.
    Nature, 1963, Aug-31, Volume: 199

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Mice; Neoplasm Regression, Spontaneous; Neoplasm

1963
FAILURE OF MONO-CHLOROACETONE TO INFLUENCE 3,4-BENZPYRENE MOUSE SKIN TUMORIGENESIS.
    Experientia, 1963, Nov-15, Volume: 19

    Topics: Acetone; Animals; Antineoplastic Agents; Benzo(a)pyrene; Benzopyrenes; Cell Transformation, Neoplast

1963
[ON THE INTERACTION IN VIVO OF 3,4-BENZOPYRENE AND MOUSE SKIN DESOXYRIBONUCLEIC ACID].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1964, Jun-08, Volume: 258

    Topics: Benzo(a)pyrene; Benzopyrenes; DNA; Mice; Neoplasms; Research; Skin Neoplasms; Toxicology

1964
Chemomodulatory efficacy of basil leaf (Ocimum basilicum) on drug metabolizing and antioxidant enzymes, and on carcinogen-induced skin and forestomach papillomagenesis.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2004, Volume: 11, Issue:2-3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Catalase; Glutat

2004
Chemopreventive potential of Azadirachta indica (Neem) leaf extract in murine carcinogenesis model systems.
    Journal of ethnopharmacology, 2004, Volume: 92, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Anticarcinogenic Agents; Antioxidan

2004
Tumor prevalence and biomarkers of exposure and response in brown bullhead (Ameiurus nebulosus) from the Anacostia River, Washington, DC and Tuckahoe River, Maryland, USA.
    Environmental toxicology and chemistry, 2004, Volume: 23, Issue:3

    Topics: Analysis of Variance; Animals; Benzo(a)pyrene; Bile; Catfishes; Chromatography, Gas; Chromatography,

2004
Deficiency of NRH:quinone oxidoreductase 2 increases susceptibility to 7,12-dimethylbenz(a)anthracene and benzo(a)pyrene-induced skin carcinogenesis.
    Cancer research, 2004, Sep-01, Volume: 64, Issue:17

    Topics: Animals; bcl-2-Associated X Protein; Benz(a)Anthracenes; Benzo(a)pyrene; Carcinogens; Cocarcinogenes

2004
Lower induction of p53 and decreased apoptosis in NQO1-null mice lead to increased sensitivity to chemical-induced skin carcinogenesis.
    Cancer research, 2005, Mar-15, Volume: 65, Issue:6

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Apoptosis; Benzo(a)pyrene; Carcinogens;

2005
Combined subcarcinogenic benzo[a]pyrene and UVA synergistically caused high tumor incidence and mutations in H-ras gene, but not p53, in SKH-1 hairless mouse skin.
    International journal of cancer, 2005, Aug-20, Volume: 116, Issue:2

    Topics: Animals; Benzo(a)pyrene; Codon; DNA Mutational Analysis; Female; Genes, p53; Genes, ras; Mice; Point

2005
Induction of invasive mouse skin carcinomas in transgenic mice with mutations in both H-ras and p53.
    Molecular cancer research : MCR, 2005, Volume: 3, Issue:10

    Topics: Animals; Benzo(a)pyrene; Carcinogens; Carcinoma, Squamous Cell; Cocarcinogenesis; Female; Genes, p53

2005
Inhibitory effect of ailanthoidol on 12-O-tetradecanoyl-phorbol-13-acetate-induced tumor promotion in mouse skin.
    Oncology reports, 2006, Volume: 16, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Benzo(a)pyrene; Benzofurans; Carcinogens;

2006
Urban dust particulate matter alters PAH-induced carcinogenesis by inhibition of CYP1A1 and CYP1B1.
    Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 95, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Transformati

2007
[Melatonin suppresses benz(a)pyrene-induced carcinogenesis in mice].
    Voprosy onkologii, 2007, Volume: 53, Issue:1

    Topics: Animals; Antioxidants; Benzo(a)pyrene; Catalase; Cell Transformation, Neoplastic; Female; Malondiald

2007
Inducibility of cytochrome P450 1A1 and chemical carcinogenesis by benzo[a]pyrene in AhR repressor-deficient mice.
    Biochemical and biophysical research communications, 2008, Jan-18, Volume: 365, Issue:3

    Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Benzo(a)pyrene; Cell Transformation, Neoplast

2008
The influence of diesel exhaust on polycyclic aromatic hydrocarbon-induced DNA damage, gene expression, and tumor initiation in Sencar mice in vivo.
    Cancer letters, 2008, Jun-28, Volume: 265, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Transformati

2008
Clotrimazole, an inhibitor of epidermal benzo(a)pyrene metabolism and DNA binding and carcinogenicity of the hydrocarbon.
    Cancer research, 1984, Volume: 44, Issue:10

    Topics: Animals; Animals, Newborn; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Carcinogens;

1984
Skin carcinogenesis studies of emission extracts.
    Developments in toxicology and environmental science, 1982, Volume: 10

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Coke; Dose-Response Relationship, Drug; Female;

1982
Dermal carcinogenesis bioassays of diesel particulates and dichloromethane extract of diesel particulates in C3H mice.
    Developments in toxicology and environmental science, 1982, Volume: 10

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Dose-Response Relationship, Drug; Male; Methylen

1982
Prevention of the benzo(a)pyrene photocarcinogenic effect by beta-carotene and canthaxanthine. Preliminary study.
    Bollettino chimico farmaceutico, 1980, Volume: 119, Issue:12

    Topics: Adult; Animals; Benzo(a)pyrene; Benzopyrenes; beta Carotene; Biotransformation; Canthaxanthin; Carot

1980
Effect of temperature on benzo[a]pyrene-induced hyperplastic and neoplastic skin lesions in mice.
    Journal of the National Cancer Institute, 1981, Volume: 66, Issue:5

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; F

1981
Light induced interactions of benzo[a]pyrene with carboxylic acids.
    Photochemistry and photobiology, 1981, Volume: 33, Issue:2

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carboxylic Acids; Humans; Light; Mice; Neoplasms, Experimenta

1981
Comparison of the tumor-initiating activity of 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene in female SENCAR and CS-1 mice.
    Carcinogenesis, 1980, Volume: 1, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Carcino

1980
Carcinogenicity of the environmental pollutants cyclopenteno-[cd]pyrene and cyclopentano[cd]pyrene in mouse skin.
    Carcinogenesis, 1981, Volume: 2, Issue:4

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cyclopentanes; Environmental Pollutants; Mice; N

1981
In vivo formation of benzo(alpha)pyrene diol epoxide-deoxyadenosine adducts in the skin of mice susceptible to benzo(alpha)pyrene-induced carcinogenesis.
    International journal of cancer, 1981, Mar-15, Volume: 27, Issue:3

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Deoxyadenosines; DNA; Female; Mice; Mice, Inbred

1981
Anticarcinogenic and cocarcinogenic effects of benzo[e]pyrene and dibenz[a,c]anthracene on skin tumor initiation by polycyclic hydrocarbons.
    Carcinogenesis, 1982, Volume: 3, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; DNA; Dr

1982
Differential effects of retinoic acid and 7,8-benzoflavone on the induction of mouse skin tumors by the complete carcinogenesis process and by the initiation-promotion regimen.
    Cancer research, 1982, Volume: 42, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzoflavones; Benzop

1982
Metabolism and tumorigenicity of 7-, 8-, 9-, and 10-fluorobenzo(a)pyrenes.
    Cancer research, 1982, Volume: 42, Issue:11

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Carcinogens; Female; Mice; Mice, Inbred St

1982
[Blastomogenic action of surface-active compounds, the components of synthetic detergents for the population].
    Gigiena i sanitariia, 1982, Issue:7

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinoma, Squamous Cell; Mice; Mice, Inbred C57BL; Mice, Inb

1982
Comparative tumor initiating activity on mouse skin of 6-nitrobenzo[a]pyrene, 6-nitrochrysene, 3-nitroperylene, 1-nitropyrene and their parent hydrocarbons.
    Cancer letters, 1982, Volume: 16, Issue:3

    Topics: Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Chrysenes; Female; Mice; Mic

1982
Formation of benzo(a)pyrene/DNA adducts and their relationship to tumor initiation in mouse epidermis.
    Cancer research, 1983, Volume: 43, Issue:3

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; DNA; Dose-Response Relationship, Drug; Epidermis; Half-Life;

1983
Dosimetry of PAH skin carcinogenesis: covalent binding of benzo[a]pyrene to mouse epidermal DNA.
    Carcinogenesis, 1983, Volume: 4, Issue:2

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Chromatography, High Pressure Liquid; DNA; Femal

1983
Acceleration of the development of benzopyrene-induced skin cancer in mice by microwave radiation.
    Archives of dermatological research, 1982, Volume: 274, Issue:3-4

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cocarcinogen

1982
Relationship of benign papillomas to cancer induction in mouse skin.
    Cancer detection and prevention, 1981, Volume: 4, Issue:1-4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Dose-Response Relationship,

1981
Syncarcinogenic effect of the environmental pollutants cyclopenteno[cd]pyrene and benzo[a]pyrene in mouse skin.
    Carcinogenesis, 1983, Volume: 4, Issue:4

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Drug Synergism; Environmental Pollution; Female;

1983
Crude petroleum and selected fractions. Skin cancer bioassays.
    Progress in experimental tumor research, 1983, Volume: 26

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Biological Assay; Male; Mice; Neoplasms, Experimental; Petrol

1983
Skin tumor promotion: a comparative study of several stocks and strains of mice.
    Basic life sciences, 1983, Volume: 24

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Mice; Mice, Inbred Strains; Neoplasms, Experimen

1983
Initiation/promotion studies with coal-derived liquids.
    Journal of applied toxicology : JAT, 1983, Volume: 3, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Coal; Male; Mice; Mice, Inb

1983
Fluorine substitution as a probe for the role of the 6-position of benzo[a]pyrene in carcinogenesis.
    Journal of the National Cancer Institute, 1983, Volume: 71, Issue:2

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Female; Liver Neoplasms, Experimental; Lung Neop

1983
Acceleration of skin tumorigenesis in mice by submandibular and sublingual gland excision.
    Carcinogenesis, 1983, Volume: 4, Issue:9

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Kinetics; Male; Mice; Neoplasms, Experimental; S

1983
Dietary carotenoids block photocarcinogenic enhancement by benzo (a)pyrene and inhibit its carcinogenesis in the dark.
    Experientia, 1983, Sep-15, Volume: 39, Issue:9

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; beta Carotene; Canthaxanthin; Carotenoids; Darkness; Diet; Fe

1983
The carcinogenic effect of a series of petroleum-derived oils on the skin of mice.
    Environmental research, 1983, Volume: 32, Issue:2

    Topics: Animals; Behavior, Animal; Benzo(a)pyrene; Benzopyrenes; Female; Mice; Mortality; Petroleum; Polycyc

1983
Protective effects of ellagic acid and other plant phenols on benzo[a]pyrene-induced neoplasia in mice.
    Carcinogenesis, 1983, Volume: 4, Issue:12

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Benzo(a)pyrene; Benzopyrans; Benzopyrenes; Carci

1983
Influence of 13-cis-retinoic acid on mouse skin tumor initiation and promotion.
    Cancer letters, 1984, Volume: 22, Issue:1

    Topics: Animals; Anthralin; Benzo(a)pyrene; Benzopyrenes; Female; Isotretinoin; Methylnitronitrosoguanidine;

1984
Murine susceptibility to two-stage skin carcinogenesis is influenced by the agent used for promotion.
    Carcinogenesis, 1984, Volume: 5, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Carcinog

1984
[Effect of phenols on the level of gene mutations and carcinogenesis induced by benzo(a)pyrene].
    Doklady Akademii nauk SSSR, 1984, Volume: 274, Issue:3

    Topics: Animals; Antioxidants; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Genes; Mice; Mutagens; Mutation; P

1984
Protection against 3-methylcholanthrene-induced skin tumorigenesis in Balb/C mice by ellagic acid.
    Biochemical and biophysical research communications, 1984, Mar-15, Volume: 119, Issue:2

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrans; Benzopyrenes; Carcinogens; DNA;

1984
Tumor-initiating activity of quinoline and methylated quinolines on the skin of SENCAR mice.
    Cancer letters, 1984, Volume: 22, Issue:3

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Cocarcinogenesis; Female; Mice; Mutagens; Quinaldines; Quinol

1984
In vitro analysis of multistage epidermal carcinogenesis: development of indefinite renewal capacity and reduced growth factor requirements in colony forming keratinocytes precedes malignant transformation.
    Carcinogenesis, 1984, Volume: 5, Issue:5

    Topics: Animals; Animals, Newborn; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Carcinoma, Squamous Cell; Cell

1984
Benzo(a)pyrene-DNA adduct formation and removal in mouse epidermis in vivo and in vitro: relationship of DNA binding to initiation of skin carcinogenesis.
    Cancer research, 1984, Volume: 44, Issue:9

    Topics: Animals; Animals, Newborn; Benzo(a)pyrene; Benzopyrenes; Carcinogens; DNA; Dose-Response Relationshi

1984
Investigation on the carcinogenicity of emission condensate from brown coal-fired residential furnaces applied to mouse skin.
    Cancer letters, 1984, Volume: 25, Issue:1

    Topics: Air Pollutants; Animals; Benzo(a)pyrene; Coal; Dose-Response Relationship, Drug; Female; Heating; Mi

1984
Pharmacological and toxicological investigations of cesium.
    Pharmacology, biochemistry, and behavior, 1984, Volume: 21 Suppl 1

    Topics: Animals; Avoidance Learning; Behavior, Animal; Benzo(a)pyrene; Blood Pressure; Catalepsy; Cesium; Dr

1984
Coke production.
    IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 1984, Volume: 34

    Topics: Air Pollutants, Occupational; Animals; Benzo(a)pyrene; Carcinogens; Coal; Coke; Humans; Industry; Mi

1984
Positive immunohistochemical staining of p53 and cyclin D in advanced mouse skin tumors, but not in precancerous lesions produced by benzo[a]pyrene.
    Carcinogenesis, 1995, Volume: 16, Issue:7

    Topics: Animals; Benzo(a)pyrene; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cyclins; Disease Progression;

1995
Lack of concordant p53 mutations in some paired primary and metastatic mouse squamous cell carcinomas induced by chemical carcinogenesis.
    Molecular carcinogenesis, 1995, Volume: 12, Issue:2

    Topics: Animals; Base Sequence; Benzo(a)pyrene; Carcinoma, Squamous Cell; DNA Primers; DNA, Neoplasm; Genes,

1995
Chemically-induced unscheduled DNA synthesis in cultures of adult human epidermal keratinocytes.
    Mutation research, 1993, Volume: 291, Issue:2

    Topics: Adult; Benzo(a)pyrene; Carcinogenicity Tests; Carcinoma, Squamous Cell; Cells, Cultured; DNA; DNA Da

1993
"Tumour suppressor gene" concept of carcinogenesis.
    Lancet (London, England), 1995, Jun-17, Volume: 345, Issue:8964

    Topics: Alleles; Animals; Benzo(a)pyrene; Cell Division; Gene Expression Regulation, Neoplastic; Genes, Tumo

1995
Inhibition of tumor promotion in benzo[a]pyrene-initiated CD-1 mouse skin by crocetin.
    Carcinogenesis, 1995, Volume: 16, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carotenoids; Edema; Enzyme Induction; Female; Hydr

1995
Potential genoprotective role for UDP-glucuronosyltransferases in chemical carcinogenesis: initiation of micronuclei by benzo(a)pyrene and benzo(e)pyrene in UDP-glucuronosyltransferase-deficient cultured rat skin fibroblasts.
    Cancer research, 1995, Mar-01, Volume: 55, Issue:5

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Bilirubin; Cells, Cultured; Cocarcinogenesis; Fibroblasts; Gl

1995
Carcinogenicity of 7H-dibenzo[c,g]carbazole, dibenz[a,j]acridine and benzo[a]pyrene in mouse skin and liver following topical application.
    Toxicology, 1994, Nov-11, Volume: 93, Issue:2-3

    Topics: Acridines; Administration, Topical; Animals; Benzo(a)pyrene; Carbazoles; Carcinogens; DNA Adducts; F

1994
Murine squamous cell carcinoma cell lines produced by a complete carcinogenesis protocol with benzo[a]pyrene exhibit characteristic p53 mutations and the absence of H-ras and cyl 1/cyclin D1 abnormalities.
    Carcinogenesis, 1994, Volume: 15, Issue:8

    Topics: Animals; Benzo(a)pyrene; Carcinoma, Squamous Cell; Cyclin D1; Cyclins; Genes, p53; Genes, ras; Mice;

1994
2-year carcinogenicity study in the male NMRI mouse with 2-ethylhexyl acrylate by epicutaneous administration.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1994, Volume: 32, Issue:3

    Topics: Acrylates; Administration, Cutaneous; Air Pollutants, Occupational; Animals; Benzo(a)pyrene; Carcino

1994
Effects of krestin (PSK) on tumorigenesis induced by two-stage and complete chemical carcinogenesis.
    The Journal of dermatology, 1994, Volume: 21, Issue:1

    Topics: Adjuvants, Immunologic; Animals; Antibiotics, Antineoplastic; Benzo(a)pyrene; Carcinoma, Squamous Ce

1994
Effects of isothiocyanates on tumorigenesis by benzo[a]pyrene in murine tumor models.
    Cancer letters, 1993, Nov-01, Volume: 74, Issue:3

    Topics: Animals; Benzo(a)pyrene; Drug Screening Assays, Antitumor; Female; Isothiocyanates; Lung Neoplasms;

1993
Tumorigenicity of a combination of psoriasis therapies.
    British journal of cancer, 1994, Volume: 69, Issue:6

    Topics: Adenosine Triphosphate; Administration, Topical; Animals; Anthralin; Benzo(a)pyrene; Carcinogens; Co

1994
Inhibition of two-stage skin carcinogenesis as well as complete skin carcinogenesis by oral administration of TMK688, a potent lipoxygenase inhibitor.
    Carcinogenesis, 1994, Volume: 15, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Administration, Topical; Animals; Anticarcin

1994
Mouse skin tumor-initiating activity of benz[j]aceanthrylene in SENCAR mice.
    Cancer letters, 1993, Sep-30, Volume: 73, Issue:2-3

    Topics: Animals; Benzo(a)pyrene; Carcinogens; Dose-Response Relationship, Drug; Female; Methylcholanthrene;

1993
Characterization of benzo[a]pyrene-initiated mouse skin papillomas for Ha-ras mutations and protein kinase C levels.
    Carcinogenesis, 1993, Volume: 14, Issue:11

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Base Sequence; Benzo(a)pyrene; Codon; DNA, Neopl

1993
Dose- and time-dependent expression of transforming growth factor-beta 1 mRNA and protein in mouse epidermis and papillomas after repeated topical application of benzo[a]pyrene.
    Molecular carcinogenesis, 1993, Volume: 8, Issue:4

    Topics: Administration, Topical; Animals; Benzo(a)pyrene; Dose-Response Relationship, Drug; Epidermis; Femal

1993
Further analysis of c-Ha-ras mutations in papillomas initiated by several polycyclic aromatic hydrocarbons and papillomas from uninitiated, promoter-treated skin in SENCAR mice.
    Molecular carcinogenesis, 1993, Volume: 8, Issue:4

    Topics: Animals; Base Sequence; Benz(a)Anthracenes; Benzo(a)pyrene; Carcinogens; Codon; DNA, Neoplasm; Femal

1993
Inhibition of skin tumorigenesis by rosemary and its constituents carnosol and ursolic acid.
    Cancer research, 1994, Feb-01, Volume: 54, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Abietanes; Animals; Anticarcinogenic Agents; Antioxidants; Arachid

1994
Exceptional tumor-initiating activity of 4-fluorobenzo[j]-fluoranthene on mouse skin: comparison with benzo[j]-fluoranthene, 10-fluoro-benzo[j]fluoranthene, benzo[a]pyrene, dibenzo[a,l]pyrene and 7,12-dimethylbenz[a]anthracene.
    Cancer letters, 1993, Jun-15, Volume: 70, Issue:1-2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Female; Fluorenes; Mice; Skin Neoplasms

1993
Benzo[a]pyrene-induced murine skin tumors exhibit frequent and characteristic G to T mutations in the p53 gene.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Feb-01, Volume: 90, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinoma, Squamous Cell; Genes, Tumor Su

1993
12-O-tetradecanoylphorbol-13-acetate-mediated systemic co-promotion in the murine skin multistage carcinogenesis protocol.
    Carcinogenesis, 1993, Volume: 14, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Female; Mice; Skin Neoplasms

1993
Tumor-initiating activity and carcinogenicity of dibenzo[a,l]pyrene versus 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene at low doses in mouse skin.
    Carcinogenesis, 1993, Volume: 14, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Carci

1993
Factors affecting carcinogenic potential of mixtures.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1993, Volume: 20, Issue:3

    Topics: Alkanes; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Carcinogens; Coal Tar; Dose-Response Relations

1993
Chemopreventive activity of chlorophyllin against mouse skin carcinogenesis by benzo[a]pyrene and benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide.
    Cancer letters, 1996, Apr-19, Volume: 102, Issue:1-2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Anticarcinogenic Agents; Benzo(a)pyrene

1996
Effect of free fatty acids on two-stage skin carcinogenesis in mice.
    Cancer letters, 1996, Feb-27, Volume: 100, Issue:1-2

    Topics: Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carcinogens; Cell Division; Cocarcinogenesis; Crot

1996
Behavior of the basement membrane during carcinoma cell invasion in chemically induced carcinomas of the skin.
    Acta anatomica, 1996, Volume: 155, Issue:1

    Topics: Animals; Basement Membrane; Benzo(a)pyrene; Collagen; Collagenases; Female; Immunohistochemistry; In

1996
Inhibitory effect of TMK688 on skin tumor initiation caused by 7,12-dimethylbenz[a]anthracene in relation to inhibition of aryl hydrocarbon hydroxylase activity and Cyp1a1 mRNA induction.
    Pharmacology, 1996, Volume: 53, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Administration, Topical; Animals; Anti-Infla

1996
Genetics of chemical carcinogenesis--III. Tissue-specificity of the genes controlling susceptibility and resistance to skin carcinogenesis in the mouse.
    Carcinogenesis, 1996, Volume: 17, Issue:11

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Cocarcinogenesis; Disease Su

1996
Dose-related preventive and therapeutic effects of antioxidants-anticarcinogens on experimentally induced malignant tumors in Wistar rats.
    Cancer letters, 1997, May-01, Volume: 115, Issue:1

    Topics: Administration, Oral; Animals; Anticarcinogenic Agents; Antioxidants; Benzo(a)pyrene; Leiomyosarcoma

1997
Increased expression of G1 cyclins and cyclin-dependent kinases during tumor progression of chemically induced mouse skin neoplasms.
    Molecular carcinogenesis, 1997, Volume: 18, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Carcinoma, Squamous Cell; Ce

1997
Ornithine decarboxylase overexpression is a sufficient condition for tumor promotion in mouse skin.
    Cancer research, 1997, Jul-01, Volume: 57, Issue:13

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Animals, Newborn; Benzo(a)pyrene; Hair Folli

1997
Effect of naturally occurring coumarins on the formation of epidermal DNA adducts and skin tumors induced by benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in SENCAR mice.
    Carcinogenesis, 1997, Volume: 18, Issue:8

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Coumarins; DNA Adducts; Dose-Response Rel

1997
Chemopreventive effect of difluoromethylornithine (DFMO) on mouse skin squamous cell carcinomas induced by benzo(a)pyrene.
    Journal of cellular biochemistry. Supplement, 1997, Volume: 28-29

    Topics: Animals; Benzo(a)pyrene; Carcinogens; Carcinoma, Squamous Cell; Eflornithine; Female; Hyperplasia; M

1997
Comparative tumorigenicity of 1- and 3-nitrobenzo[a]pyrenes, and 3,6- and 1,6-dinitrobenzo[a]pyrenes in F344/DuCrj rats.
    Toxicology letters, 1998, Sep-01, Volume: 98, Issue:1-2

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Body Weight; Carcinogenicity Tests; Carcinogens; Injections,

1998
Tumor promoting effect of N-nitroso-N-(2-hexanonyl)-3'-nitrotyramine (a nitrosated Maillard reaction product) in benzo(a)pyrene-initiated mouse skin carcinogenesis.
    Chemico-biological interactions, 1998, Aug-14, Volume: 115, Issue:1

    Topics: Animals; Benzo(a)pyrene; Carcinogens; Cocarcinogenesis; Dose-Response Relationship, Drug; Ear; Edema

1998
Effect of evening primrose and fish oils on two stage skin carcinogenesis in mice.
    Prostaglandins, leukotrienes, and essential fatty acids, 1998, Volume: 59, Issue:3

    Topics: Animals; Benzo(a)pyrene; Carcinogens; DNA; Fatty Acids; Fatty Acids, Essential; Fish Oils; gamma-Lin

1998
Antitumour activity of diallyl sulfide on polycyclic aromatic hydrocarbon-induced mouse skin carcinogenesis.
    Cancer letters, 1998, Sep-25, Volume: 131, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Allyl Compounds; Animals; Antineoplastic Agents; Benzo(a)pyrene; F

1998
Inhibitory effects of isopropyl-2-(1,3-dithietane-2-ylidene)-2- [N-(4-methylthiazol-2-yl)carbamoyl]acetate (YH439) on benzo[a]pyrene-induced skin carcinogenesis and micronucleated reticulocyte formation in mice.
    Mutation research, 1999, Jan-25, Volume: 423, Issue:1-2

    Topics: Animals; Anticarcinogenic Agents; Antimutagenic Agents; Antineoplastic Agents; Benzo(a)pyrene; Cross

1999
Dose-dependent mutation profile in the c-Ha-ras proto-oncogene of skin tumors in mice initiated with benzo[a]pyrene.
    Carcinogenesis, 1999, Volume: 20, Issue:9

    Topics: Administration, Cutaneous; Amino Acid Substitution; Animals; Benzo(a)pyrene; Carcinogens; Carcinoma

1999
Inhibitory effect of 12-O-tetradecanoylphorbol-13-acetate-caused tumor promotion in benzo[a]pyrene-initiated CD-1 mouse skin by baicalein.
    Nutrition and cancer, 1999, Volume: 34, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carcinogens; Drug Screening Assays, Antitumor; Fem

1999
Benzo[a]pyrene carcinogenicity is lost in mice lacking the aryl hydrocarbon receptor.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Jan-18, Volume: 97, Issue:2

    Topics: Animals; Benzo(a)pyrene; Carcinogens; Carcinoma, Squamous Cell; Female; Fibrosarcoma; Gene Expressio

2000
Mutagenesis and carcinogenesis in nucleotide excision repair-deficient XPA knock out mice.
    Mutation research, 2000, May-30, Volume: 450, Issue:1-2

    Topics: 2-Acetylaminofluorene; Animals; Base Sequence; Benzo(a)pyrene; Cocarcinogenesis; DNA Repair; DNA-Bin

2000
Inducible nitric oxide synthase mRNA is upregulated in skin tumors of v-ha-ras transgenic TG-AC mice treated with 12-o-tetradecanoylphorbol-13-acetate.
    Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:7

    Topics: Animals; Benzo(a)pyrene; Carcinogens; Female; Gene Expression Regulation, Enzymologic; Gene Expressi

2000
NAD(P)H:quinone oxidoreductase 1 deficiency increases susceptibility to benzo(a)pyrene-induced mouse skin carcinogenesis.
    Cancer research, 2000, Nov-01, Volume: 60, Issue:21

    Topics: Animals; Benzo(a)pyrene; Biotransformation; Carcinogens; Cocarcinogenesis; Disease Susceptibility; F

2000
Cancer chemopreventive activities of S-3-1, a synthetic derivative of danshinone.
    Journal of Asian natural products research, 2001, Volume: 3, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Benzofurans; Bep

2001
Tumourigenic studies on deltamethrin in Swiss albino mice.
    Toxicology, 2001, May-28, Volume: 163, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Benzo(a)pyrene; Carcinogenicity

2001
Relationship of selenium to cancer. I. Inhibitory effect of selenium on carcinogenesis.
    Journal of the National Cancer Institute, 1970, Volume: 44, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antioxidants; Benzo(a)pyrene; Carci

1970
Dietary N-acetyl-L-cysteine modulates benzo[a]pyrene-induced skin tumors in cancer-prone p53 haploinsufficient Tg.AC (v-Ha-ras) mice.
    Carcinogenesis, 2001, Volume: 22, Issue:9

    Topics: Acetylcysteine; Animals; Antioxidants; Benzo(a)pyrene; Carcinogens; Carcinoma, Squamous Cell; Cocarc

2001
To BaP or not to BaP? That is the question.
    Environmental health perspectives, 2001, Volume: 109, Issue:8

    Topics: Administration, Inhalation; Administration, Oral; Administration, Topical; Animals; Benzo(a)pyrene;

2001
Elevated levels of high-mobility-group chromosomal proteins, HMGA1, in murine skin carcinoma.
    Cancer letters, 2001, Nov-08, Volume: 173, Issue:1

    Topics: Acetic Acid; Animals; Benzo(a)pyrene; Biomarkers, Tumor; Blotting, Western; Carcinoma; Chromatograph

2001
Chemomodulation of carcinogen metabolising enzymes, antioxidant profiles and skin and forestomach papillomagenesis by Spirulina platensis.
    Molecular and cellular biochemistry, 2001, Volume: 226, Issue:1-2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Benzo(a)pyrene; Body Weight; Carcinogens; C

2001
Metabolism of benzo[a]pyrene in human skin xenografts.
    Cancer biochemistry biophysics, 1992, Volume: 13, Issue:1

    Topics: Animals; Benzo(a)pyrene; Humans; Infant, Newborn; Male; Mice; Mice, Inbred C57BL; Mice, Nude; Models

1992
Inhibitory effects of curcumin on tumor initiation by benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene.
    Carcinogenesis, 1992, Volume: 13, Issue:11

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Benzo(a)pyrene; Curcumin; DNA; D

1992
Carcinogenic and cocarcinogenic studies with carbaryl following topical exposure in mice.
    Cancer letters, 1992, Feb-29, Volume: 62, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Benzo(a)pyrene; Carbaryl; Carcin

1992
Chemopreventive effect of turmeric against stomach and skin tumors induced by chemical carcinogens in Swiss mice.
    Nutrition and cancer, 1992, Volume: 17, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Curcumin; Diet; Female; Glutathione Trans

1992
Inhibitory effect of topical application of a green tea polyphenol fraction on tumor initiation and promotion in mouse skin.
    Carcinogenesis, 1992, Volume: 13, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Benzo(a)pyrene; Edema; Enzyme In

1992
Immunohistochemical characterization of cellular infiltrates in epidermal tumors induced by two-stage and complete chemical carcinogenesis in mouse skin.
    The Journal of dermatology, 1992, Volume: 19, Issue:3

    Topics: Animals; Benzo(a)pyrene; Carcinoma, Squamous Cell; Female; Killer Cells, Natural; Lymphocytes, Tumor

1992
Comparative tumor-initiating ability of 7H-dibenzo(c,g)carbazole and dibenz(a,j)acridine in mouse skin.
    Toxicology, 1992, Volume: 71, Issue:3

    Topics: Acetone; Acridines; Animals; Benzo(a)pyrene; Carbazoles; Carcinogens; Female; Mice; Papilloma; Skin;

1992
Inhibition of chemically-induced skin carcinogenesis in mice by peanut oil preparations.
    Bulletin du cancer, 1991, Volume: 78, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Arachis; Benzo(a)pyrene; Female; Male; Mice; Mic

1991
Potent inhibitory effects of suicide inhibitors of P450 isozymes on 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene initiated skin tumors.
    Carcinogenesis, 1991, Volume: 12, Issue:7

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Cytochrome P-450 Enzyme Inhibitors; DNA;

1991
A role for prostaglandins in the suppression of cutaneous cellular immunity and tumour development in benzo(a)pyrene- but not dimethylbenz(a)anthracene-treated mice.
    Clinical and experimental immunology, 1991, Volume: 85, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigen-Presenti

1991
Development and field-test validation of an assay for DNA repair in circulating human lymphocytes.
    Cancer research, 1991, Nov-01, Volume: 51, Issue:21

    Topics: Adult; B-Lymphocytes; Benzo(a)pyrene; Carcinoma, Basal Cell; Cell Line; Cell Line, Transformed; Chlo

1991
Comparative dose-response tumorigenicity studies of dibenzo[alpha,l]pyrene versus 7,12-dimethylbenz[alpha]anthracene, benzo[alpha]pyrene and two dibenzo[alpha,l]pyrene dihydrodiols in mouse skin and rat mammary gland.
    Carcinogenesis, 1991, Volume: 12, Issue:10

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogenicity Tests; Carc

1991
Cell kinetics and benzo[a]pyrene-DNA adducts in mouse skin tumorigenesis.
    Progress in clinical and biological research, 1991, Volume: 369

    Topics: Animals; Benzo(a)pyrene; Carcinogens; Cell Division; DNA; DNA Adducts; Female; Keratinocytes; Kineti

1991
Benzo[a]pyrene-induced skin damage and tumor promotion in the mouse.
    Carcinogenesis, 1991, Volume: 12, Issue:7

    Topics: Animals; Benzo(a)pyrene; Cell Division; DNA; Dose-Response Relationship, Drug; Female; Mice; Mice, I

1991
Oxidation of polycyclic hydrocarbons by oxygen radicals.
    Princess Takamatsu symposia, 1990, Volume: 21

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; Cytochrome P-450 Enzyme

1990
Estimation of epidermal carcinogenic potency.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1990, Volume: 15, Issue:2

    Topics: Animals; Benzo(a)pyrene; Carcinogenicity Tests; Dose-Response Relationship, Drug; Male; Mice; Mice,

1990
Gap-junctional intercellular communication in epidermal cell lines from selected stages of SENCAR mouse skin carcinogenesis.
    Cancer research, 1989, Feb-01, Volume: 49, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Calcium; Cell Communication; Cell Line; E

1989
Influences of complex organic mixtures on tumor-initiating activity, DNA binding and adducts of benzo[a]pyrene.
    Carcinogenesis, 1989, Volume: 10, Issue:1

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; Biotransformation; Chem

1989
Differential effects of benzo[a]pyrene and dimethylbenz[a]-anthracene on Langerhans cell distribution and contact sensitization in murine epidermis.
    The Journal of investigative dermatology, 1989, Volume: 92, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Cell Count; Dermatitis, Cont

1989
Protection against chemically induced skin tumorigenesis in SENCAR mice by tannic acid.
    International journal of cancer, 1989, Mar-15, Volume: 43, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Cutaneous; Animals; Antineoplastic Agents, Phytoge

1989
Effect of dietary tannic acid on epidermal, lung, and forestomach polycyclic aromatic hydrocarbon metabolism and tumorigenicity in Sencar mice.
    Cancer research, 1989, Nov-01, Volume: 49, Issue:21

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Cytosol; D

1989
Effects of catechol on the induction of tumors in mouse skin by 7,8-dihydroxy-7,8-dihydrobenzo[a]pyrenes.
    Carcinogenesis, 1989, Volume: 10, Issue:10

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; Catechols; Dihydroxydih

1989
Mouse skin papillomas as a stage in cancer progression.
    Progress in clinical and biological research, 1989, Volume: 298

    Topics: Animals; Benzo(a)pyrene; Cell Division; Cocarcinogenesis; Mice; Papilloma; Skin Neoplasms; Tetradeca

1989
Transplacental induction of a specific mutation in fetal Ha-ras and its critical role in post-natal carcinogenesis.
    International journal of cancer, 1987, Dec-15, Volume: 40, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinoma; Cocarcinogenesis; DNA, Neoplas

1987
Benzo(a)pyrene metabolism, DNA-binding and UV-induced repair of DNA damage in cultured skin fibroblasts from a patient with unilateral multiple basal cell carcinoma.
    The British journal of dermatology, 1989, Volume: 120, Issue:2

    Topics: Benz(a)Anthracenes; Benzo(a)pyrene; Carcinoma, Basal Cell; Cells, Cultured; DNA; DNA Damage; DNA Rep

1989
Inhibitory effect of toluene on tumor promotion in mouse skin.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1986, Volume: 181, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Cocarcinogenesis; Drug Antag

1986
Correlation between formation of a specific hydrocarbon-deoxyribonucleoside adduct and tumor-initiating activity of 7,12-dimethylbenz(a)anthracene and its 9- and 10-monofluoroderivatives in mice.
    Cancer research, 1986, Volume: 46, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenine; Animals; Benzo(a)pyrene; Biotransformation; Carcinogens;

1986
Inhibition and enhancement of skin tumors in mice by dimethyl sulfoxide depending on method of application.
    Journal of the National Cancer Institute, 1986, Volume: 77, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Dimethyl Sulfoxide; Drug Interactions; Ma

1986
Benzo(a)pyrene diol epoxide-I-DNA adduct formation in the epidermis and lung of SENCAR mice following topical application of crude coal tar.
    Cancer letters, 1986, Volume: 33, Issue:3

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Administration, Topical; Animals; Benzo(a)pyrene

1986
Benzo(e)pyrene-induced alterations in the binding of benzo(a)pyrene and 7,12-dimethylbenz(a)anthracene to DNA in Sencar mouse epidermis.
    Cancer research, 1987, Jul-15, Volume: 47, Issue:14

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Cocarcinogenesis; DNA; Epid

1987
Initiating, promoting and carcinogenic activities of three naphthofurans in a mouse skin long-term study.
    Japanese journal of cancer research : Gann, 1987, Volume: 78, Issue:6

    Topics: Animals; Benzo(a)pyrene; Cocarcinogenesis; Furans; Mice; Nitrofurans; Skin Neoplasms; Structure-Acti

1987
Further investigations into the effect of non-benzo ring bay-region methyl substituents on tumor-initiating activity of polycyclic hydrocarbons.
    Cancer letters, 1987, Volume: 36, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Carcino

1987
Comparison of the histological changes in the skin of DBA/2 and C57BL/6 mice following exposure to various promoting agents.
    Carcinogenesis, 1987, Volume: 8, Issue:12

    Topics: Animals; Anthracenes; Benzo(a)pyrene; Carcinogens; Diterpenes; Lyngbya Toxins; Mast Cells; Mice; Mic

1987
Exceptional activity of tannic acid among naturally occurring plant phenols in protecting against 7,12-dimethylbenz(a)anthracene-, benzo(a)pyrene-, 3-methylcholanthrene-, and N-methyl-N-nitrosourea-induced skin tumorigenesis in mice.
    Cancer research, 1988, May-01, Volume: 48, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Anthraquinones; Benzo(a)pyrene;

1988
Survey of cytotoxicities and antimutagenic and antitumor initiating activities of Cu(II)(3,5-diisopropylsalicylate)2 and its analogs in a keratinocyte-mediated mutation assay and the murine skin multistage carcinogenesis model.
    Carcinogenesis, 1988, Volume: 9, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Benzo(a)pyrene; Cell Line; Cell Su

1988
Chemoprevention of indirect and direct chemical carcinogenesis by carotenoids as oxygen radical quenchers.
    Annals of the New York Academy of Sciences, 1988, Volume: 534

    Topics: Animals; Benzo(a)pyrene; beta Carotene; Canthaxanthin; Carcinogens; Carotenoids; Diet; Female; Free

1988
[Carcinogenic effect of benz(a)pyrene depending on its mode of application to the skin of mice].
    Eksperimental'naia onkologiia, 1988, Volume: 10, Issue:4

    Topics: Administration, Cutaneous; Animals; Benzo(a)pyrene; Dose-Response Relationship, Drug; Female; Mice;

1988
Enhancement of chemical carcinogenesis in mice by systemic effects of ultraviolet irradiation.
    Cancer research, 1988, Feb-01, Volume: 48, Issue:3

    Topics: Benzo(a)pyrene; DNA Damage; Dose-Response Relationship, Radiation; Neoplasms, Experimental; Neoplasm

1988
Tumorigenicity of 6-halogenated derivatives of benzo[a]pyrene in mouse skin and rat mammary gland.
    Journal of cancer research and clinical oncology, 1988, Volume: 114, Issue:1

    Topics: Animals; Benzo(a)pyrene; Free Radicals; Hydrocarbons, Halogenated; Mammary Neoplasms, Experimental;

1988
Tumor-initiating activity in mouse skin and carcinogenicity in rat mammary gland of fluorinated derivatives of benzo[a]pyrene and 3-methylcholanthrene.
    Journal of cancer research and clinical oncology, 1988, Volume: 114, Issue:1

    Topics: Animals; Benzo(a)pyrene; Biotransformation; Female; Hydrocarbons, Fluorinated; Mammary Neoplasms, Ex

1988
Dose-response relationships of the tumorigenicity of cyclopenta[cd]pyrene, benzo[a]pyrene and 6-nitrochrysene in a newborn mouse lung adenoma bioassay.
    Carcinogenesis, 1988, Volume: 9, Issue:5

    Topics: Adenoma; Animals; Animals, Newborn; Benzo(a)pyrene; Biological Assay; Carcinogens; Chrysenes; Dose-R

1988
Inhibitory action of garlic oil on the initiation of benzo[a]pyrene-induced skin carcinogenesis in mice.
    Cancer letters, 1988, Jun-15, Volume: 40, Issue:2

    Topics: Allyl Compounds; Animals; Benzo(a)pyrene; Female; Mice; Skin Neoplasms; Sulfides

1988
Periodic response difference in mouse epidermis chronically exposed to crude-oils or BaP: males vs. females.
    Toxicology, 1988, Volume: 50, Issue:1

    Topics: Administration, Cutaneous; Animals; Benzo(a)pyrene; Carcinogens; Female; Fuel Oils; Male; Mice; Mice

1988
Carcinogenic property of JBO(P) variety of jute batching oil.
    Drug and chemical toxicology, 1988, Volume: 11, Issue:2

    Topics: Animals; Benzo(a)pyrene; Carcinogens; Carcinoma, Squamous Cell; Female; Keratoacanthoma; Mice; Miner

1988
Presence of benz(a)pyrene in soil, room dust & in water samples of Azarbaijan Province of Iran & the carcinogenic activity on back skin of NMRI mice.
    Indian journal of cancer, 1987, Volume: 24, Issue:1

    Topics: Animals; Benzo(a)pyrene; Carcinoma; Dust; Environmental Pollutants; Housing; Iran; Mice; Mice, Inbre

1987
Skin tumorigenic potential of crude and refined coal liquids and analogous petroleum products.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1987, Volume: 9, Issue:2

    Topics: Animals; Benzo(a)pyrene; Carcinogens; Coal; Female; Male; Mice; Mice, Inbred C3H; Organ Size; Petrol

1987
Comparative carcinogenic potencies of 7H-dibenzo[c,g]carbazole, dibenz[a,j]acridine and benzo[a]pyrene in mouse skin.
    Cancer letters, 1987, Volume: 37, Issue:3

    Topics: Acridines; Animals; Benzo(a)pyrene; Carbazoles; Carcinogens; Mice; Neoplasms, Experimental; Skin Neo

1987
[Benzo(a)pyrene and the carcinogenic effect of coal tar].
    Voprosy onkologii, 1987, Volume: 33, Issue:10

    Topics: Animals; Benzo(a)pyrene; Coal Tar; Dose-Response Relationship, Drug; Female; Mice; Mutagenicity Test

1987
Evidence that a slowly cycling subpopulation of adult murine epidermal cells retains carcinogen.
    Cancer research, 1986, Volume: 46, Issue:6

    Topics: Animals; Autoradiography; Benzo(a)pyrene; Carbon Radioisotopes; Carcinogens; Cell Division; Epiderma

1986
Human epidermal blister: a convenient tissue for toxicological and genetic studies of benzo(a)pyrene metabolism.
    Archives of dermatological research, 1986, Volume: 278, Issue:4

    Topics: Aged; Benzo(a)pyrene; Blister; Carcinogens; Coal Tar; Culture Techniques; Humans; Male; Middle Aged;

1986
Pharmacological modification of epidermal detoxification systems.
    The British journal of dermatology, 1986, Volume: 115 Suppl 31

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Carcinogens; Clotrimazole; Cytochrome P-450

1986
Effect of ellagic acid and 3-O-decylellagic acid on the formation of benzo[a]pyrene-derived DNA adducts in vivo and on the tumorigenicity of 3-methylcholanthrene in mice.
    Carcinogenesis, 1986, Volume: 7, Issue:10

    Topics: Animals; Antineoplastic Agents; Benzo(a)pyrene; Benzopyrans; DNA; Dose-Response Relationship, Drug;

1986
Comparison of the tumorigenic response of SENCAR and C57BL/6 mice to benzo(a)pyrene and the inter-experimental variability over a three-year period.
    Environmental health perspectives, 1986, Volume: 68

    Topics: Animals; Benzo(a)pyrene; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Male; Mice; M

1986
Metabolic activation of benzo(a)pyrene in SENCAR and BALB/c mouse embryo cell cultures.
    Environmental health perspectives, 1986, Volume: 68

    Topics: Animals; Benzo(a)pyrene; Biotransformation; Cells, Cultured; DNA; Embryo, Mammalian; Mice; Mice, Inb

1986
Binding and distribution studies in the SENCAR mouse of compounds demonstrating a route-dependent tumorigenic effect.
    Environmental health perspectives, 1986, Volume: 68

    Topics: Acrylamide; Acrylamides; Administration, Oral; Administration, Topical; Animals; Benzo(a)pyrene; Car

1986
Influence of housing conditions for mice on the results of a dermal oncogenicity bioassay.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1986, Volume: 7, Issue:4

    Topics: Animals; Benzo(a)pyrene; Body Weight; Carcinoma; Dental Cements; Male; Mice; Mice, Inbred C3H; Papil

1986
Role of radical cations in aromatic hydrocarbon carcinogenesis.
    Environmental health perspectives, 1985, Volume: 64

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Carcinogens; DNA; Electrons; Female; Free

1985
Coal-tars and derived products.
    IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 1985, Volume: 35

    Topics: Animals; Benzo(a)pyrene; Carcinogens; Chemical Phenomena; Chemistry; Coal Tar; Hot Temperature; Huma

1985
Formation and disappearance of benzo[a]pyrene DNA-adducts in mouse epidermis.
    Carcinogenesis, 1985, Volume: 6, Issue:5

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; Benzopyrenes; DNA; Fema

1985
Effect of ellagic acid and hydroxylated flavonoids on the tumorigenicity of benzo[a]pyrene and (+/-)-7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene on mouse skin and in the newborn mouse.
    Carcinogenesis, 1985, Volume: 6, Issue:8

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Animals, Newborn; Benzo(a)pyrene; Benzo

1985
Local application to mouse skin as a carcinogen specific test system for non-volatile nitroso compounds.
    Cancer letters, 1985, Volume: 29, Issue:1

    Topics: Administration, Topical; Animals; Benzo(a)pyrene; Carbaryl; Carcinogens; Dose-Response Relationship,

1985
Studies on the tumor initiating, tumor promoting, and tumor co-initiating properties of respiratory carcinogens.
    Carcinogenesis; a comprehensive survey, 1985, Volume: 8

    Topics: Animals; Benzo(a)pyrene; Beryllium; Carcinogens; Cocarcinogenesis; Female; Fuel Oils; Male; Methylen

1985
[Effect of antioxidants on the carcinogenic and mutagenic activity of benzo[a]pyrene].
    Voprosy onkologii, 1985, Volume: 31, Issue:4

    Topics: Animals; Antioxidants; Benzo(a)pyrene; Biotransformation; Cell Line; Cell Survival; Cricetinae; Cric

1985
Promotion of preneoplastic changes in liver by coal-derived organic mixtures applied to skin.
    Cancer letters, 1985, Sep-15, Volume: 28, Issue:2

    Topics: Administration, Topical; Animals; Benzo(a)pyrene; Coal; Diethylnitrosamine; Female; Liver Neoplasms,

1985