benzo(a)pyrene has been researched along with Breast Neoplasms in 91 studies
Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (8.79) | 18.7374 |
| 1990's | 20 (21.98) | 18.2507 |
| 2000's | 42 (46.15) | 29.6817 |
| 2010's | 16 (17.58) | 24.3611 |
| 2020's | 5 (5.49) | 2.80 |
| Authors | Studies |
|---|---|
| Lao, QF | 3 |
| Zhang, QQ | 3 |
| Qiao, ZP | 3 |
| Li, SL | 3 |
| Liu, L | 5 |
| Martin, FL | 6 |
| Pang, WY | 3 |
| Hong, S | 2 |
| Song, JM | 1 |
| Pedersen, JE | 1 |
| Hansen, J | 1 |
| Malik, DE | 2 |
| David, RM | 2 |
| Gooderham, NJ | 2 |
| Nese, M | 1 |
| Riboli, G | 1 |
| Brighetti, G | 1 |
| Sassi, V | 1 |
| Camela, E | 1 |
| Caselli, G | 1 |
| Sassaroli, S | 1 |
| Borlimi, R | 1 |
| Aucoin, M | 1 |
| Cooley, K | 1 |
| Saunders, PR | 1 |
| Carè, J | 1 |
| Anheyer, D | 1 |
| Medina, DN | 1 |
| Cardozo, V | 1 |
| Remy, D | 1 |
| Hannan, N | 1 |
| Garber, A | 1 |
| Velayos, M | 1 |
| Muñoz-Serrano, AJ | 1 |
| Estefanía-Fernández, K | 1 |
| Sarmiento Caldas, MC | 1 |
| Moratilla Lapeña, L | 1 |
| López-Santamaría, M | 1 |
| López-Gutiérrez, JC | 1 |
| Li, J | 1 |
| Zhang, J | 1 |
| Shen, S | 1 |
| Zhang, B | 2 |
| Yu, WW | 1 |
| Toyoda, H | 1 |
| Huang, DQ | 1 |
| Le, MH | 1 |
| Nguyen, MH | 1 |
| Huang, R | 1 |
| Zhu, L | 1 |
| Wang, J | 6 |
| Xue, L | 1 |
| Yan, X | 2 |
| Huang, S | 1 |
| Li, Y | 6 |
| Xu, T | 1 |
| Li, C | 2 |
| Ji, F | 1 |
| Ming, F | 1 |
| Zhao, Y | 2 |
| Cheng, J | 1 |
| Wang, Y | 3 |
| Zhao, H | 1 |
| Chen, K | 2 |
| Zhao, XA | 1 |
| Zou, L | 1 |
| Sang, D | 1 |
| Shao, H | 1 |
| Guan, X | 1 |
| Chen, X | 2 |
| Chen, Y | 5 |
| Wei, J | 1 |
| Zhu, C | 1 |
| Wu, C | 1 |
| Moore, HB | 1 |
| Barrett, CD | 1 |
| Moore, EE | 1 |
| Jhunjhunwala, R | 1 |
| McIntyre, RC | 1 |
| Moore, PK | 1 |
| Hajizadeh, N | 1 |
| Talmor, DS | 1 |
| Sauaia, A | 1 |
| Yaffe, MB | 1 |
| Liu, C | 3 |
| Lin, Y | 1 |
| Dong, Y | 1 |
| Wu, Y | 1 |
| Bao, Y | 1 |
| Yan, H | 2 |
| Ma, J | 1 |
| Fernández-Cuadros, ME | 1 |
| Albaladejo-Florín, MJ | 1 |
| Álava-Rabasa, S | 1 |
| Usandizaga-Elio, I | 1 |
| Martinez-Quintanilla Jimenez, D | 1 |
| Peña-Lora, D | 1 |
| Neira-Borrajo, I | 1 |
| López-Muñoz, MJ | 1 |
| Rodríguez-de-Cía, J | 1 |
| Pérez-Moro, OS | 1 |
| Abdallah, M | 1 |
| Alsaleh, H | 1 |
| Baradwan, A | 1 |
| Alfawares, R | 1 |
| Alobaid, A | 1 |
| Rasheed, A | 1 |
| Soliman, I | 1 |
| Wendel Garcia, PD | 1 |
| Fumeaux, T | 1 |
| Guerci, P | 1 |
| Heuberger, DM | 1 |
| Montomoli, J | 2 |
| Roche-Campo, F | 1 |
| Schuepbach, RA | 1 |
| Hilty, MP | 1 |
| Poloni, TE | 1 |
| Carlos, AF | 1 |
| Cairati, M | 1 |
| Cutaia, C | 1 |
| Medici, V | 1 |
| Marelli, E | 1 |
| Ferrari, D | 1 |
| Galli, A | 1 |
| Bognetti, P | 1 |
| Davin, A | 1 |
| Cirrincione, A | 1 |
| Ceretti, A | 1 |
| Cereda, C | 1 |
| Ceroni, M | 1 |
| Tronconi, L | 1 |
| Vitali, S | 1 |
| Guaita, A | 1 |
| Leeds, JS | 1 |
| Raviprakash, V | 1 |
| Jacques, T | 1 |
| Scanlon, N | 1 |
| Cundall, J | 1 |
| Leeds, CM | 1 |
| Riva, A | 1 |
| Gray, EH | 1 |
| Azarian, S | 1 |
| Zamalloa, A | 1 |
| McPhail, MJW | 1 |
| Vincent, RP | 1 |
| Williams, R | 1 |
| Chokshi, S | 1 |
| Patel, VC | 1 |
| Edwards, LA | 1 |
| Alqarawi, W | 1 |
| Birnie, DH | 1 |
| Golian, M | 1 |
| Nair, GM | 1 |
| Nery, PB | 1 |
| Klein, A | 1 |
| Davis, DR | 1 |
| Sadek, MM | 1 |
| Neilipovitz, D | 1 |
| Johnson, CB | 1 |
| Green, MS | 1 |
| Redpath, C | 1 |
| Miller, DC | 1 |
| Beamer, P | 1 |
| Billheimer, D | 1 |
| Subbian, V | 1 |
| Sorooshian, A | 1 |
| Campbell, BS | 1 |
| Mosier, JM | 1 |
| Novaretti, JV | 1 |
| Astur, DC | 1 |
| Cavalcante, ELB | 1 |
| Kaleka, CC | 1 |
| Amaro, JT | 1 |
| Cohen, M | 1 |
| Huang, W | 1 |
| Li, T | 1 |
| Ling, Y | 1 |
| Qian, ZP | 1 |
| Zhang, YY | 1 |
| Huang, D | 1 |
| Xu, SB | 1 |
| Liu, XH | 1 |
| Xia, L | 1 |
| Yang, Y | 3 |
| Lu, SH | 1 |
| Lu, HZ | 1 |
| Zhang, R | 2 |
| Ma, JX | 1 |
| Tang, S | 1 |
| Li, CM | 1 |
| Wan, J | 1 |
| Wang, JF | 1 |
| Ma, JQ | 1 |
| Luo, JJ | 1 |
| Chen, HY | 2 |
| Mi, SL | 1 |
| Chen, SY | 1 |
| Su, YG | 1 |
| Ge, JB | 1 |
| Milheiro, SA | 1 |
| Gonçalves, J | 1 |
| Lopes, RMRM | 1 |
| Madureira, M | 1 |
| Lobo, L | 1 |
| Lopes, A | 1 |
| Nogueira, F | 1 |
| Fontinha, D | 1 |
| Prudêncio, M | 1 |
| M Piedade, MF | 1 |
| Pinto, SN | 1 |
| Florindo, PR | 1 |
| Moreira, R | 1 |
| Castillo-Lora, J | 1 |
| Delley, MF | 1 |
| Laga, SM | 1 |
| Mayer, JM | 1 |
| Sutjarit, N | 1 |
| Thongon, N | 1 |
| Weerachayaphorn, J | 1 |
| Piyachaturawat, P | 1 |
| Suksamrarn, A | 1 |
| Suksen, K | 1 |
| Papachristou, DJ | 1 |
| Blair, HC | 1 |
| Hu, Y | 1 |
| Shen, P | 1 |
| Zeng, N | 1 |
| Wang, L | 3 |
| Yan, D | 1 |
| Cui, L | 1 |
| Yang, K | 2 |
| Zhai, C | 1 |
| Yang, M | 1 |
| Lao, X | 1 |
| Sun, J | 1 |
| Ma, N | 1 |
| Wang, S | 1 |
| Ye, W | 1 |
| Guo, P | 1 |
| Rahimi, S | 1 |
| Singh, MP | 1 |
| Gupta, J | 1 |
| Nakanishi, I | 1 |
| Ohkubo, K | 1 |
| Shoji, Y | 1 |
| Fujitaka, Y | 1 |
| Shimoda, K | 1 |
| Matsumoto, KI | 1 |
| Fukuhara, K | 1 |
| Hamada, H | 1 |
| van der Boom, T | 1 |
| Gruppen, EG | 1 |
| Lefrandt, JD | 1 |
| Connelly, MA | 1 |
| Links, TP | 1 |
| Dullaart, RPF | 1 |
| Berry, JD | 1 |
| Bedlack, R | 1 |
| Mathews, D | 1 |
| Agnese, W | 1 |
| Apple, S | 1 |
| Meloncelli, S | 1 |
| Divizia, M | 1 |
| Germani, G | 1 |
| Adefegha, SA | 1 |
| Bottari, NB | 1 |
| Leal, DB | 1 |
| de Andrade, CM | 1 |
| Schetinger, MR | 1 |
| Martínez-Velasco, A | 1 |
| Perez-Ortiz, AC | 1 |
| Antonio-Aguirre, B | 1 |
| Martínez-Villaseñor, L | 1 |
| Lira-Romero, E | 1 |
| Palacio-Pastrana, C | 1 |
| Zenteno, JC | 1 |
| Ramirez, I | 1 |
| Zepeda-Palacio, C | 1 |
| Mendoza-Velásquez, C | 1 |
| Camacho-Ordóñez, A | 1 |
| Ortiz Bibriesca, DM | 1 |
| Estrada-Mena, FJ | 1 |
| Martin, BL | 1 |
| Thompson, LC | 1 |
| Kim, YH | 2 |
| Snow, SJ | 1 |
| Schladweiler, MC | 1 |
| Phillips, P | 1 |
| Harmon, M | 1 |
| King, C | 1 |
| Richards, J | 1 |
| George, I | 1 |
| Haykal-Coates, N | 1 |
| Gilmour, MI | 1 |
| Kodavanti, UP | 1 |
| Hazari, MS | 1 |
| Farraj, AK | 1 |
| Shen, Z | 1 |
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| Gao, K | 1 |
| Lazar, S | 1 |
| Wurtzel, JGT | 1 |
| Ma, P | 1 |
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| Kyttaris, VC | 1 |
| Chen, R | 1 |
| Chen, J | 2 |
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| Steinhart, C | 1 |
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| Gaikwad, S | 1 |
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| Shaheen, MY | 1 |
| Basudan, AM | 1 |
| Niazy, AA | 1 |
| van den Beucken, JJJP | 1 |
| Jansen, JA | 1 |
| Alghamdi, HS | 1 |
| Gao, Q | 2 |
| Guo, X | 1 |
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| Jia, X | 1 |
| Xu, S | 1 |
| Lu, C | 2 |
| Zhu, H | 2 |
| Melku, M | 1 |
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| Teketel, A | 1 |
| Asrie, F | 1 |
| Yalew, A | 1 |
| Biadgo, B | 1 |
| Kassa, E | 1 |
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| Anlay, DZ | 1 |
| Ahmed, MFE | 1 |
| Ramadan, H | 1 |
| Seinige, D | 1 |
| Kehrenberg, C | 1 |
| Abd El-Wahab, A | 1 |
| Volkmann, N | 1 |
| Kemper, N | 1 |
| Schulz, J | 1 |
| Hu, MY | 1 |
| Wu, YN | 1 |
| McEvoy, MP | 1 |
| Wang, YF | 1 |
| Cong, WL | 1 |
| Liu, LP | 1 |
| Li, XX | 1 |
| Zhou, CL | 1 |
| Chen, WM | 1 |
| Wei, KL | 1 |
| Tung, SY | 1 |
| Shen, CH | 1 |
| Chang, TS | 1 |
| Yen, CW | 1 |
| Hsieh, YY | 1 |
| Chiu, WN | 1 |
| Hu, JH | 1 |
| Lu, SN | 1 |
| Hung, CH | 1 |
| Alakavuklar, MA | 1 |
| Fuqua, C | 1 |
| Luo, KL | 1 |
| Underwood, RS | 1 |
| Greenwald, I | 1 |
| Elashiry, MM | 1 |
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| Zeitoun, R | 1 |
| Elsayed, R | 1 |
| Tian, F | 1 |
| Saber, SE | 1 |
| Elashry, SH | 1 |
| Tay, FR | 1 |
| Cutler, CW | 1 |
| O'Dowd, A | 1 |
| Maciel, M | 1 |
| Poole, ST | 1 |
| Jobling, MG | 1 |
| Rollenhagen, JE | 1 |
| Woods, CM | 1 |
| Sincock, SA | 1 |
| McVeigh, AL | 1 |
| Gregory, MJ | 1 |
| Maves, RC | 1 |
| Prouty, MG | 1 |
| Holmes, RK | 1 |
| Savarino, SJ | 1 |
| Mor, MK | 1 |
| Palevsky, PM | 1 |
| Kaufman, JS | 1 |
| Thiessen Philbrook, H | 1 |
| Weisbord, SD | 1 |
| Parikh, CR | 1 |
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| Jarvis, GA | 1 |
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| Kilburn, S | 1 |
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| Gray, JE | 1 |
| Hoffman, AM | 1 |
| Li, X | 4 |
| Post, AK | 1 |
| Slette, IJ | 1 |
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| Luo, Y | 1 |
| Smith, MD | 1 |
| Temitayo, GI | 1 |
| Olawande, B | 1 |
| Emmanuel, YO | 1 |
| Timothy, AT | 1 |
| Kehinde, O | 1 |
| Susan, LF | 1 |
| Ezra, L | 1 |
| Joseph, OO | 1 |
| Lev, S | 1 |
| Desmarini, D | 1 |
| Liuwantara, D | 1 |
| Sorrell, TC | 1 |
| Hawthorne, WJ | 1 |
| Djordjevic, JT | 1 |
| Verso, MG | 1 |
| Costantino, C | 1 |
| Marrella, A | 1 |
| Immordino, P | 1 |
| Vitale, F | 1 |
| Amodio, E | 1 |
| Wang, YD | 1 |
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| Xin, ZM | 1 |
| Han, TT | 1 |
| Wang, ZG | 1 |
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| Zhang, Y | 4 |
| Ba, D | 1 |
| Wen, S | 1 |
| Tian, Q | 1 |
| Lv, W | 1 |
| Cheng, G | 1 |
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| Chen, Q | 1 |
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| Zhao, X | 3 |
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| Chhoker, S | 1 |
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| Hirata, K | 1 |
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| Suga, H | 1 |
| Shun, C | 1 |
| Yong-Yi, J | 1 |
| Mei-Li, C | 1 |
| Shi-Li, L | 1 |
| Jian-Bo, Z | 1 |
| Dan-Li, W | 1 |
| Zhi-Min, G | 1 |
| Ibrahim, AM | 1 |
| Zakhary, SY | 1 |
| Amin, SAW | 1 |
| Ugurlu, M | 1 |
| Fornari, VJ | 1 |
| Hartmann, MSM | 1 |
| Vanni, JR | 1 |
| Rodriguez, R | 1 |
| Langaro, MC | 1 |
| Pelepenko, LE | 1 |
| Zaia, AA | 1 |
| Nakanjako, D | 1 |
| Zalwango, F | 1 |
| Wairagala, P | 1 |
| Luboga, F | 1 |
| Andia Biraro, I | 1 |
| Bukirwa, VD | 1 |
| Mboowa, MG | 1 |
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| Wang, X | 2 |
| Qu, G | 1 |
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| Mayr, T | 1 |
| Liu, Y | 2 |
| Zhang, Q | 2 |
| Bigliardi, AP | 1 |
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| Pinto, EA | 1 |
| Dos Santos, M | 1 |
| Garcia, EM | 1 |
| Baisch, PRM | 1 |
| Soares, MCF | 1 |
| Muccillo-Baisch, AL | 1 |
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| Yu, W | 1 |
| Ju, C | 1 |
| Wang, K | 1 |
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| Gao, Y | 1 |
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| Moratalla-López, N | 1 |
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| Alonso, GL | 1 |
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| García-Campos, C | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Breath Test to Predict Breast Cancer and Outcome of Mammography[NCT04755829] | 1,000 participants (Anticipated) | Observational | 2021-03-31 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for benzo(a)pyrene and Breast Neoplasms
| Article | Year |
|---|---|
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; | 2022 |
Estradiol metabolism: an endocrine biomarker for modulation of human mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Anticarcinogenic Agents; Benzo(a)pyrene; Biomarkers; Breast; Breas | 1997 |
Formation and repair of DNA lesions in the p53 gene: relation to cancer mutations?
Topics: 5-Methylcytosine; Animals; Benzo(a)pyrene; Breast Neoplasms; Carcinogens, Environmental; Colonic Neo | 1998 |
Tobacco smoke carcinogens and breast cancer.
Topics: Animals; Benzo(a)pyrene; Breast Neoplasms; Carcinogens; Humans; Mutagens; Polycyclic Aromatic Hydroc | 2002 |
1 trial available for benzo(a)pyrene and Breast Neoplasms
87 other studies available for benzo(a)pyrene and Breast Neoplasms
| Article | Year |
|---|---|
Whole transcriptome sequencing and competitive endogenous RNA regulation network construction analysis in benzo[a]pyrene-treated breast cancer cells.
Topics: Benzo(a)pyrene; Breast Neoplasms; Exome Sequencing; Female; Gene Regulatory Networks; Humans; MicroR | 2023 |
Whole transcriptome sequencing and competitive endogenous RNA regulation network construction analysis in benzo[a]pyrene-treated breast cancer cells.
Topics: Benzo(a)pyrene; Breast Neoplasms; Exome Sequencing; Female; Gene Regulatory Networks; Humans; MicroR | 2023 |
Whole transcriptome sequencing and competitive endogenous RNA regulation network construction analysis in benzo[a]pyrene-treated breast cancer cells.
Topics: Benzo(a)pyrene; Breast Neoplasms; Exome Sequencing; Female; Gene Regulatory Networks; Humans; MicroR | 2023 |
Whole transcriptome sequencing and competitive endogenous RNA regulation network construction analysis in benzo[a]pyrene-treated breast cancer cells.
Topics: Benzo(a)pyrene; Breast Neoplasms; Exome Sequencing; Female; Gene Regulatory Networks; Humans; MicroR | 2023 |
High-Resolution In Situ High-Content Imaging of 3D-Bioprinted Single Breast Cancer Spheroids for Advanced Quantification of Benzo(
Topics: Benzo(a)pyrene; Breast Neoplasms; Carcinogens; Cell Line, Tumor; Female; Humans; Neoplastic Stem Cel | 2023 |
Parental occupational exposure to chemicals and risk of breast cancer in female offspring.
Topics: Benzo(a)pyrene; Breast Neoplasms; Case-Control Studies; Female; Humans; Male; Occupational Exposure; | 2023 |
Interleukin-6 selectively induces drug metabolism to potentiate the genotoxicity of dietary carcinogens in mammary cells.
Topics: Benzo(a)pyrene; Breast Neoplasms; Carcinogens; Cell Line, Tumor; Cytochrome P-450 CYP1B1; DNA Damage | 2019 |
Risk of breast cancer associated with long-term exposure to benzo[a]pyrene (BaP) air pollution: Evidence from the French E3N cohort study.
Topics: Air Pollution; Benzo(a)pyrene; Breast Neoplasms; Case-Control Studies; Cohort Studies; Female; Human | 2021 |
Mechanistic evidence that benzo[a]pyrene promotes an inflammatory microenvironment that drives the metastatic potential of human mammary cells.
Topics: Benzo(a)pyrene; Breast Neoplasms; Carcinogens; Cyclooxygenase 2; Female; Gene Expression Regulation, | 2018 |
Invasion and migration of MDA-MB-231 cells are inhibited by block of AhR and NFAT: role of AhR/NFAT1/β4 integrin signaling.
Topics: Benzo(a)pyrene; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Survival; Cyclosporine; Dose | 2019 |
Carvedilol suppresses malignant proliferation of mammary epithelial cells through inhibition of the ROS‑mediated PI3K/AKT signaling pathway.
Topics: Antioxidants; Benzo(a)pyrene; Breast; Breast Neoplasms; Carvedilol; Cell Line; Cell Proliferation; C | 2019 |
Adenomatous polyposis coli-mediated accumulation of abasic DNA lesions lead to cigarette smoke condensate-induced neoplastic transformation of normal breast epithelial cells.
Topics: Adenomatous Polyposis Coli Protein; Animals; Apurinic Acid; Benzo(a)pyrene; Breast; Breast Neoplasms | 2013 |
Chronic exposure to combined carcinogens enhances breast cell carcinogenesis with mesenchymal and stem-like cell properties.
Topics: Benzo(a)pyrene; Breast Neoplasms; Carcinogenesis; Carcinogens; DNA Damage; Drug Synergism; Epithelia | 2014 |
Effects of exposure to benzo[a]pyrene on metastasis of breast cancer are mediated through ROS-ERK-MMP9 axis signaling.
Topics: Animals; Benzo(a)pyrene; Breast Neoplasms; Carcinogens; Cell Movement; Female; Humans; Mammary Neopl | 2015 |
Distinguishing nuclei-specific benzo[a]pyrene-induced effects from whole-cell alterations in MCF-7 cells using Fourier-transform infrared spectroscopy.
Topics: Benzo(a)pyrene; Biomarkers; Breast Neoplasms; Cell Nucleus; DNA Damage; Female; Humans; MCF-7 Cells; | 2015 |
Estrogens and genomic instability in human breast cancer cells--involvement of Src/Raf/Erk signaling in micronucleus formation by estrogenic chemicals.
Topics: Benzhydryl Compounds; Benzo(a)pyrene; Breast Neoplasms; Cell Line, Tumor; Estradiol; Estrogens; Extr | 2008 |
Grape seed proanthocyanidin suppression of breast cell carcinogenesis induced by chronic exposure to combined 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and benzo[a]pyrene.
Topics: Base Sequence; Benzo(a)pyrene; Blotting, Western; Breast Neoplasms; Carcinogens; Cell Adhesion; Cell | 2010 |
Green tea catechin extract in intervention of chronic breast cell carcinogenesis induced by environmental carcinogens.
Topics: Benzo(a)pyrene; Breast; Breast Neoplasms; Carcinogens, Environmental; Catechin; Cell Line; Cell Prol | 2012 |
Green tea catechin intervention of reactive oxygen species-mediated ERK pathway activation and chronically induced breast cell carcinogenesis.
Topics: Benzo(a)pyrene; Breast Neoplasms; Catechin; Cell Proliferation; Cells, Cultured; DNA Damage; Extrace | 2012 |
Dietary benzo[a]pyrene, alcohol drinking, and risk of breast cancer: a case-control study in Uruguay.
Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Benzo(a)pyrene; Breast Neoplasms; Case-Control Stu | 2011 |
Bioactive food components prevent carcinogenic stress via Nrf2 activation in BRCA1 deficient breast epithelial cells.
Topics: Anticarcinogenic Agents; Benzo(a)pyrene; Blotting, Western; BRCA1 Protein; Breast Neoplasms; Cell Li | 2012 |
Dipyridamole intervention of breast cell carcinogenesis.
Topics: Apoptosis; Benzo(a)pyrene; Blotting, Western; Breast; Breast Neoplasms; Carcinogens; Cell Adhesion; | 2014 |
Benzo[α]pyrene repressed DNA mismatch repair in human breast cancer cells.
Topics: Benzo(a)pyrene; Blotting, Western; Breast Neoplasms; Carcinogens; Cell Line, Tumor; DNA Mismatch Rep | 2013 |
Mesenchymal and stem-like cell properties targeted in suppression of chronically-induced breast cell carcinogenesis.
Topics: Benzo(a)pyrene; Breast Neoplasms; Catechin; Cell Transformation, Neoplastic; Epithelial-Mesenchymal | 2013 |
Genetic and environmental determinants on tissue response to in vitro carcinogen exposure and risk of breast cancer.
Topics: Adult; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Breast Neoplasms; Case-Control Studies; Cocarc | 2002 |
Oestrogens induce G(1) arrest in benzo[a]pyrene-treated MCF-7 breast cells whilst enhancing genotoxicity and clonogenic survival.
Topics: Benzo(a)pyrene; Breast Neoplasms; Cell Division; Cell Survival; Colony-Forming Units Assay; DNA Dama | 2002 |
Naturally occurring coumarins inhibit human cytochromes P450 and block benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene DNA adduct formation in MCF-7 cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Antineoplastic Agents; Benzo(a)pyrene; Breast Neoplasms; Carcinoge | 2003 |
Nanosensor for in vivo measurement of the carcinogen benzo[a]pyrene in a single cell.
Topics: Antibodies; Benzo(a)pyrene; Biosensing Techniques; Breast Neoplasms; Carcinogens; Equipment Design; | 2002 |
DEPOSITION OF BENZO(A)PYRENE IN MOUSE FAT AFTER ORAL ADMINISTRATION.
Topics: Adipose Tissue; Administration, Oral; Animals; Benzo(a)pyrene; Benzopyrenes; Breast Neoplasms; Glyce | 1964 |
Ethanol inhibits benzo[a]pyrene-DNA adduct removal and increases 8-oxo-deoxyguanosine formation in human mammary epithelial cells.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetaldehyde; Benzo(a)pyrene; Breast Neoplasms; Cell Line, Tumor; Deoxy | 2004 |
Antiestrogenic effects of motorcycle exhaust particulate in MCF-7 human breast cancer cells and immature female rats.
Topics: Air Pollutants; Animals; Benzo(a)pyrene; Benzoflavones; Binding, Competitive; Breast Neoplasms; Cell | 2004 |
Deregulation of cell proliferation by polycyclic aromatic hydrocarbons in human breast carcinoma MCF-7 cells reflects both genotoxic and nongenotoxic events.
Topics: Benz(a)Anthracenes; Benzo(a)pyrene; Benzothiazoles; Breast Neoplasms; Bromodeoxyuridine; Carcinogens | 2005 |
Altered gene expression patterns in MCF-7 cells induced by the urban dust particulate complex mixture standard reference material 1649a.
Topics: Apoptosis; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Breast Neoplasms; Carcinogens; Cell Cycl | 2005 |
Beta catenin is associated with breast cancer progression in vitro.
Topics: Benzo(a)pyrene; beta Catenin; Breast Neoplasms; Cell Transformation, Neoplastic; Cytoskeletal Protei | 2005 |
Pentameric procyanidin from Theobroma cacao selectively inhibits growth of human breast cancer cells.
Topics: Antioxidants; Benzo(a)pyrene; Biflavonoids; Breast; Breast Neoplasms; Catechin; Cell Line, Tumor; Ce | 2005 |
Benzo-[a]-pyrene increases invasion in MDA-MB-231 breast cancer cells via increased COX-II expression and prostaglandin E2 (PGE2) output.
Topics: Benzo(a)pyrene; Blotting, Western; Breast Neoplasms; Carcinogens; Cyclooxygenase 2; Dinoprostone; Fe | 2005 |
Oncoprotein expression and morphological phenotypes of human breast epithelial cells transformed by the c-Ha-ras oncogene.
Topics: Benzo(a)pyrene; Breast Neoplasms; Carcinogens; Cell Differentiation; Cell Line, Transformed; Cell Li | 2005 |
Long-term effects of a standardized complex mixture of urban dust particulate on the metabolic activation of carcinogenic polycyclic aromatic hydrocarbons in human cells in culture.
Topics: Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Breast Neoplasms; Ca | 2005 |
Effect of estrogen receptor (ER) on benzo[a]pyrene-DNA adduct formation in human breast cancer cells.
Topics: Benzo(a)pyrene; Breast Neoplasms; Cell Transformation, Neoplastic; DNA Adducts; Female; Humans; Rece | 2005 |
Potent inhibition of carcinogen-bioactivating cytochrome P450 1B1 by the p53 inhibitor pifithrin alpha.
Topics: Apoptosis; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzothiazoles; Breast Neoplasms; Carcinog | 2006 |
The ligand status of the aromatic hydrocarbon receptor modulates transcriptional activation of BRCA-1 promoter by estrogen.
Topics: Benzo(a)pyrene; BRCA1 Protein; Breast Neoplasms; Estradiol; Estrogen Receptor alpha; Gene Expression | 2006 |
An intronic polymorphism associated with increased XRCC1 expression, reduced apoptosis and familial breast cancer.
Topics: Adenine; Adult; Apoptosis; Base Sequence; Benzo(a)pyrene; Breast Neoplasms; Carcinogens; Case-Contro | 2006 |
Carcinogen-induced DNA double strand break repair in sporadic breast cancer.
Topics: Benzo(a)pyrene; Bleomycin; BRCA2 Protein; Breast Neoplasms; Carcinogens; Comet Assay; DNA; DNA Damag | 2006 |
Induction of the transferrin receptor gene by benzo[a]pyrene in breast cancer MCF-7 cells: potential as a biomarker of PAH exposure.
Topics: Benzo(a)pyrene; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Female; Gene Expression Profi | 2006 |
Cigarette smoke condensate-induced level of adenomatous polyposis coli blocks long-patch base excision repair in breast epithelial cells.
Topics: Adenomatous Polyposis Coli Protein; Benzo(a)pyrene; Breast; Breast Neoplasms; Cell Line; Cell Line, | 2007 |
Aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha in MCF-7 breast cancer cells.
Topics: Benzo(a)pyrene; Benzofurans; Binding Sites; Breast Neoplasms; Cell Line, Tumor; Cytochrome P-450 CYP | 2006 |
DNA damage by benzo(a)pyrene in human cells is increased by cigarette smoke and decreased by a filter containing rosemary extract, which lowers free radicals.
Topics: Benzo(a)pyrene; Breast Neoplasms; Cell Line, Tumor; DNA; DNA Damage; DNA, Neoplasm; Female; Filtrati | 2006 |
DNA content and chromatin texture of human breast epithelial cells transformed with 17-beta-estradiol and the estrogen antagonist ICI 182,780 as assessed by image analysis.
Topics: Benzo(a)pyrene; Breast; Breast Neoplasms; Cell Line, Transformed; Cell Nucleus; Cell Transformation, | 2007 |
Anthocyanin-rich grape extract blocks breast cell DNA damage.
Topics: Anthocyanins; Benzo(a)pyrene; Breast; Breast Neoplasms; Cell Division; Cell Line, Transformed; Cytoc | 2007 |
Induction of CYP1A1 and CYP1B1 by benzo(k)fluoranthene and benzo(a)pyrene in T-47D human breast cancer cells: roles of PAH interactions and PAH metabolites.
Topics: Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Biotransformation; Breast Neoplasms; Cell Line, Tumor | 2008 |
Genome-wide H3K9 histone acetylation profiles are altered in benzopyrene-treated MCF7 breast cancer cells.
Topics: Acetylation; Benzo(a)pyrene; Breast Neoplasms; Cell Line, Tumor; Chromatin Immunoprecipitation; Gene | 2008 |
Enhanced micronucleus formation and modulation of BCL-2:BAX in MCF-7 cells after exposure to binary mixtures.
Topics: bcl-2-Associated X Protein; Benzo(a)pyrene; Breast Neoplasms; Cell Line, Tumor; Cyclin-Dependent Kin | 2007 |
Benzo(a)pyrene increases phosphorylation of p53 at serine 392 in relation to p53 induction and cell death in MCF-7 cells.
Topics: Adenocarcinoma; Apoptosis; Benzo(a)pyrene; Breast Neoplasms; Carcinogens; Cell Line, Tumor; Cell Pro | 2008 |
Proteomic analysis of MCF-7 cells treated with benzo[a]pyrene, dibenzo[a,l]pyrene, coal tar extract, and diesel exhaust extract.
Topics: Benzo(a)pyrene; Benzopyrenes; Breast Neoplasms; Carcinogens; Cell Line, Tumor; Coal Tar; Electrophor | 2008 |
Aryl hydrocarbon hydroxylase activity in mouse, rat, and human mammary tumors.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthofla | 1981 |
Identification of a benzo[a]pyrene-like binding protein involved in circulating immune complexes of patients with mammary tumors.
Topics: Antigen-Antibody Complex; Autoantibodies; Benzo(a)pyrene; Breast Neoplasms; Carrier Proteins; Humans | 1995 |
Benzo[a]pyrene-resistant MCF-7 human breast cancer cells. A unique aryl hydrocarbon-nonresponsive clone.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Benzo(a)pyrene; Breast Neopl | 1994 |
Hormone receptors and cathepsin D levels in human breast epithelial cells transformed by chemical carcinogens and c-Ha-ras transfection.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Breast; Breast Neoplasms; Cathepsin D; Ce | 1994 |
Aromatic DNA adducts in adjacent tissues of breast cancer patients: clues to breast cancer etiology.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Benzo(a)pyrene; Breast; Breast Neoplasms; Carcinogens; | 1996 |
Isolation and characterization of variant benzo[a]pyrene-resistant T47D human breast-cancer cells.
Topics: Base Sequence; Benzo(a)pyrene; Breast Neoplasms; Cell Division; Cytochrome P-450 Enzyme System; DNA | 1996 |
Lipid peroxidation-induced putative malondialdehyde-DNA adducts in human breast tissues.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Benzo(a)pyrene; Biomarkers, Tumor; Body Mass Index; Bre | 1996 |
Carcinogenic polycyclic aromatic hydrocarbons increase intracellular Ca2+ and cell proliferation in primary human mammary epithelial cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Benzo(a)pyrene; Benzoflavones; Breast; Breast Neoplasms; Calcium; | 1997 |
Inhibition of proliferation and modulation of estradiol metabolism: novel mechanisms for breast cancer prevention by the phytochemical indole-3-carbinol.
Topics: Anticarcinogenic Agents; Apoptosis; Benzo(a)pyrene; Breast; Breast Neoplasms; Carcinogens; Cell Divi | 1997 |
Inhibition of BRCA-1 expression by benzo[a]pyrene and its diol epoxide.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benzo(a)pyrene; Blotting, Western; Breast Neopla | 1999 |
RNA relocation at mitosis in transformed and tumorigenic human breast epithelial cells.
Topics: Benzo(a)pyrene; Biological Transport, Active; Breast Neoplasms; Cell Line, Transformed; Cell Nucleol | 1999 |
Intracellular measurements in mammary carcinoma cells using fiber-optic nanosensors.
Topics: Animals; Benzo(a)pyrene; Biosensing Techniques; Breast Neoplasms; Cell Line; Epithelial Cells; Femal | 2000 |
Misclassification in case-control studies of gene-environment interactions: assessment of bias and sample size.
Topics: Benzo(a)pyrene; Bias; Body Mass Index; Breast Neoplasms; Case-Control Studies; Cocarcinogenesis; Eff | 1999 |
Ha-ras oncogene effect on DNA content and chromatin supraorganization in benzo[a]pyrene-transformed human breast epithelial cells.
Topics: Benzo(a)pyrene; Breast Neoplasms; Cell Line, Transformed; Chromatin; Coloring Agents; DNA, Neoplasm; | 1999 |
Activity of benzo[a]pyrene and its hydroxylated metabolites in an estrogen receptor-alpha reporter gene assay.
Topics: Benzo(a)pyrene; Benzoflavones; beta-Galactosidase; Breast Neoplasms; Chromatography, High Pressure L | 2000 |
Analysis of DNA adducts by accelerator mass spectrometry in human breast tissue after administration of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and benzo[a]pyrene.
Topics: Aged; Benzo(a)pyrene; Biological Availability; Biotransformation; Breast; Breast Neoplasms; Carbon R | 2000 |
Hydroxylated benzo[a]pyrene metabolites are responsible for in vitro estrogen receptor-mediated gene expression induced by benzo[a]pyrene, but do not elicit uterotrophic effects in vivo.
Topics: Animals; Benzo(a)pyrene; Breast Neoplasms; DNA Primers; Dose-Response Relationship, Drug; Estradiol; | 2001 |
Morphological phenotypes in neoplastic progression of benz(alpha)pyrene-treated breast epithelial cells.
Topics: Animals; Benzo(a)pyrene; Breast; Breast Neoplasms; Carcinogens; Cell Line; Cell Transformation, Neop | 2000 |
Time- and dose-dependent DNA binding of PAHs derived from diesel particle extracts, benzo[a]pyrene and 5-methychrysene in a human mammary carcinoma cell line (MCF-7).
Topics: Benzo(a)pyrene; Breast Neoplasms; Carcinogenicity Tests; Carcinogens; Chrysenes; DNA Adducts; DNA, N | 2001 |
Activation of the aromatic hydrocarbon receptor pathway is not sufficient for transcriptional repression of BRCA-1: requirements for metabolism of benzo[a]pyrene to 7r,8t-dihydroxy-9t,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benzo(a)pyrene; Biotransformation; BRCA1 Protein | 2002 |
Induction of CYP1A1 and CYP1B1 in T-47D human breast cancer cells by benzo[a]pyrene is diminished by arsenite.
Topics: Arsenites; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Blotting, Western; Breast Neoplasms; Chrom | 2002 |
Aromatic DNA adducts and polymorphisms of CYP1A1, NAT2, and GSTM1 in breast cancer.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Arylamine N-Acetyltransferase; Benzo(a)pyrene; Breast; | 2002 |
Epigenetics of breast cancer: polycyclic aromatic hydrocarbons as risk factors.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benzo(a)pyrene; Benzoflavones; Blotting, Western | 2002 |
RNA relocation and persistence of nucleolus-like bodies at mitosis in benzo[a]pyrene-transformed human breast epithelial cells after microcell-mediated transfer of chromosomes 11 and 17.
Topics: Benzo(a)pyrene; Breast Neoplasms; Carcinoma; Cell Line, Transformed; Cell Nucleolus; Chromosomes, Hu | 2001 |
A new functional role for P-glycoprotein: efflux pump for benzo(alpha)pyrene in human breast cancer MCF-7 cells.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzo(a)pyrene; Breast Neoplasms; Doxorubic | 1992 |
Characterization of the 4 S polycyclic aromatic hydrocarbon-binding protein in human liver and cells.
Topics: Animals; Benzo(a)pyrene; Binding Sites; Breast Neoplasms; Carrier Proteins; Cell Fractionation; Cell | 1992 |
Identification and immunochemical characterization of IgA in sera of patients with mammary tumors.
Topics: Age Factors; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Antibody Affinity; Antibody Specifi | 1992 |
Visualization of a protein involved in seric immune complexes of patients with epithelial tumors having elevated levels of anti-'benzo[a]pyrene-like' IgA.
Topics: Antibodies, Monoclonal; Antigen-Antibody Complex; Autoantibodies; Benzo(a)pyrene; Biomarkers, Tumor; | 1991 |
Cellular ras protooncogene expression in human mammary explant cultures. A potential marker for chemical carcinogenesis.
Topics: Adult; Benzo(a)pyrene; Biomarkers, Tumor; Breast; Breast Neoplasms; Cell Transformation, Neoplastic; | 1990 |
Metabolic biotransformation of estradiol in human mammary explant cultures.
Topics: Adult; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Biomarkers, Tumor; Breast; Breast Neoplasms; C | 1990 |
Interspecies comparison of human and rat mammary epithelial cell-mediated mutagenesis by polycyclic aromatic hydrocarbons.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Biotransformation; Breast; Breast Neoplas | 1986 |
Relation between cytochrome P450IA1 expression and estrogen receptor content of human breast cancer cells.
Topics: Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Breast Neoplasms; Cell Nucleus; Cytochrome P-450 Enzy | 1989 |
Human P1-450 gene sequence and correlation of mRNA with genetic differences in benzo[a]pyrene metabolism.
Topics: Base Composition; Base Sequence; Benzo(a)pyrene; Breast Neoplasms; Cell Line; Cells, Cultured; Cytoc | 1985 |
Benzo(a)pyrene:DNA adduct formation in normal human mammary epithelial cell cultures and the human mammary carcinoma T47D cell line.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benzo(a)pyrene; Benzopyrenes; Breast; Breast Neo | 1986 |
Altered regulation of P-450IA1 expression in a multidrug-resistant MCF-7 human breast cancer cell line.
Topics: Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Blotting, Northern; Breast Neoplasms; Cell Line; Chlo | 1988 |
Benzo[a]pyrene metabolism in human T 47D mammary tumor cells: evidence for sulfate conjugation and translocation of reactive metabolites across cell membranes.
Topics: Benzo(a)pyrene; Breast Neoplasms; Cell Line; Cell Membrane; Cells, Cultured; Chromatography, High Pr | 1985 |