benzo(a)pyrene has been researched along with Arteriosclerosis in 19 studies
Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The number and size of arterial lesions in the brachiocephalic arteries in WC and SR females but not males were significantly enhanced after long-term dosing with BaP." | 1.29 | Benzo(a)pyrene enhances atherosclerosis in White Carneau and Show Racer pigeons. ( Baird, MB; Darrow, D; Hough, JL; Pacini, CS; Sfeir, GT; Wheelock, C, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (15.79) | 18.7374 |
| 1990's | 12 (63.16) | 18.2507 |
| 2000's | 4 (21.05) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Johnson, CD | 1 |
| Balagurunathan, Y | 1 |
| Lu, KP | 3 |
| Tadesse, M | 1 |
| Falahatpisheh, MH | 1 |
| Carroll, RJ | 1 |
| Dougherty, ER | 1 |
| Afshari, CA | 1 |
| Ramos, KS | 9 |
| Curfs, DM | 1 |
| Lutgens, E | 1 |
| Gijbels, MJ | 1 |
| Kockx, MM | 1 |
| Daemen, MJ | 1 |
| van Schooten, FJ | 1 |
| Revis, NW | 1 |
| Bull, R | 1 |
| Laurie, D | 1 |
| Schiller, CA | 1 |
| Bond, JA | 1 |
| Gown, AM | 1 |
| Yang, HL | 1 |
| Benditt, EP | 2 |
| Juchau, MR | 2 |
| Majesky, MW | 1 |
| Yang, HY | 1 |
| Parrish, AR | 1 |
| Ou, X | 4 |
| Weber, TJ | 2 |
| Chapkin, RS | 2 |
| Izzotti, A | 1 |
| De Flora, S | 1 |
| Petrilli, GL | 1 |
| Gallagher, J | 1 |
| Rojas, M | 1 |
| Alexandrov, K | 1 |
| Bartsch, H | 1 |
| Lewtas, J | 1 |
| Bowes, RC | 1 |
| Thirman, MJ | 1 |
| Albrecht, JH | 1 |
| Krueger, MA | 1 |
| Erickson, RR | 1 |
| Cherwitz, DL | 1 |
| Park, SS | 1 |
| Gelboin, HV | 1 |
| Holtzman, JL | 1 |
| Hough, JL | 1 |
| Baird, MB | 1 |
| Sfeir, GT | 1 |
| Pacini, CS | 1 |
| Darrow, D | 1 |
| Wheelock, C | 1 |
| Zhang, Y | 1 |
| Sadhu, DN | 1 |
| Vayssier-Taussat, M | 1 |
| Camilli, T | 1 |
| Aron, Y | 1 |
| Meplan, C | 1 |
| Hainaut, P | 1 |
| Polla, BS | 1 |
| Weksler, B | 1 |
| Alejandro, NF | 1 |
| Taylor, KM | 1 |
| Joyce, MM | 1 |
| Spencer, TE | 1 |
| Penn, A | 1 |
| Zwijsen, RM | 1 |
| van Kleef, EM | 1 |
| Alink, GM | 1 |
3 reviews available for benzo(a)pyrene and Arteriosclerosis
| Article | Year |
|---|---|
Growth-related signaling as a target of toxic insult in vascular smooth muscle cells: implications in atherogenesis.
Topics: Allylamine; Animals; Arteriosclerosis; Benzo(a)pyrene; Mitogens; Muscle, Smooth, Vascular; Phenotype | 1995 |
Responses of vascular smooth muscle cells to toxic insult: cellular and molecular perspectives for environmental toxicants.
Topics: Allylamine; Animals; Arteriosclerosis; Benzo(a)pyrene; Environmental Pollutants; Humans; Muscle, Smo | 1994 |
International Commission for Protection Against Environmental Mutagens and Carcinogens. ICPEMC Working Paper 7/1/1. Mutational events in the etiology of arteriosclerotic plaques.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arsenic; Arteriosclerosis; Benzo(a)pyrene; DNA Damage; He | 1990 |
16 other studies available for benzo(a)pyrene and Arteriosclerosis
| Article | Year |
|---|---|
Genomic profiles and predictive biological networks in oxidant-induced atherogenesis.
Topics: Algorithms; Animals; Aorta, Thoracic; Arteriosclerosis; Benzo(a)pyrene; Cells, Cultured; Cluster Ana | 2003 |
Chronic exposure to the carcinogenic compound benzo[a]pyrene induces larger and phenotypically different atherosclerotic plaques in ApoE-knockout mice.
Topics: Animals; Apolipoproteins E; Apoptosis; Arteriosclerosis; Benzo(a)pyrene; DNA Adducts; Immunohistoche | 2004 |
The effectiveness of chemical carcinogens to induce atherosclerosis in the white Carneau pigeon.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aorta, Abdominal; Arteriosclerosis; Benzo(a)pyrene; Benzo | 1984 |
Further investigations of the capacity of polynuclear aromatic hydrocarbons to elicit atherosclerotic lesions.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aorta, Abdominal; Arteriosclerosis; Benzo(a)pyrene; Benzo | 1981 |
Carcinogenesis and atherogenesis: differences in monooxygenase inducibility and bioactivation of benzo[a]pyrene in aortic and hepatic tissues of atherosclerosis-susceptible versus resistant pigeons.
Topics: Animals; Aorta; Arteriosclerosis; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Chromatography, H | 1983 |
Interference with protein kinase C-related signal transduction in vascular smooth muscle cells by benzo[a]pyrene.
Topics: Animals; Arteriosclerosis; Benzo(a)pyrene; Cells, Cultured; Mitosis; Muscle, Smooth, Vascular; Phosp | 1995 |
Cancer biomarkers in human atherosclerotic lesions: detection of DNA adducts.
Topics: Aged; Aged, 80 and over; Aorta, Abdominal; Aortic Diseases; Arteriosclerosis; Benzo(a)pyrene; Biomar | 1995 |
Induction of cytochrome CYPIA1 and formation of toxic metabolites of benzo[a]pyrene by rat aorta: a possible role in atherogenesis.
Topics: Animals; Aorta; Arteriosclerosis; Benzo(a)pyrene; Biotransformation; Cytochrome P-450 Enzyme System; | 1994 |
Benzo(a)pyrene enhances atherosclerosis in White Carneau and Show Racer pigeons.
Topics: Animals; Arteriosclerosis; Benzo(a)pyrene; Blood Pressure; Brachiocephalic Trunk; Cholesterol; Colum | 1993 |
The induction of proliferative vascular smooth muscle cell phenotypes by benzo(a)pyrene is characterized by up-regulation of inositol phospholipid metabolism and c-Ha-ras gene expression.
Topics: Animals; Arteriosclerosis; Benzo(a)pyrene; Carcinogens; Cell Division; Cells, Cultured; DNA; Genes, | 1996 |
Identification of genes differentially expressed in vascular smooth muscle cells following benzo[a]pyrene challenge: implications for chemical atherogenesis.
Topics: Aldehyde Reductase; Animals; Aorta; Apoptosis Regulatory Proteins; Arteriosclerosis; Benzo(a)pyrene; | 1998 |
Effects of tobacco smoke and benzo[a]pyrene on human endothelial cell and monocyte stress responses.
Topics: Acetylcysteine; Arteriosclerosis; Benzo(a)pyrene; Cell Death; Cells, Cultured; Endothelium, Vascular | 2001 |
Differential expression of ribosomal L31, Zis, gas-5 and mitochondrial mRNAs following oxidant induction of proliferative vascular smooth muscle cell phenotypes.
Topics: Animals; Arteriosclerosis; Benzo(a)pyrene; Blotting, Northern; Carcinogens; Cell Division; Cells, Cu | 2002 |
Modulation of aortic protein phosphorylation by benzo(a)pyrene: implications in PAH-induced atherogenesis.
Topics: Animals; Aorta; Arteriosclerosis; Benzo(a)pyrene; Cells, Cultured; Coturnix; Electrophoresis, Polyac | 1992 |
Proliferative responses of quail aortic smooth muscle cells to benzo[a]pyrene: implications in PAH-induced atherogenesis.
Topics: Animals; Aorta; Arteriosclerosis; Benzo(a)pyrene; Cells, Cultured; Coturnix; DNA; Dose-Response Rela | 1992 |
A comparative study on the metabolic activation of 3,4-benzo[a]pyrene to mutagens by aorta smooth muscle cells of rat and rabbit.
Topics: Animals; Aorta; Arteriosclerosis; Benzo(a)pyrene; Biotransformation; DNA; Genes; Hypoxanthine Phosph | 1990 |