benzo(a)pyrene has been researched along with Adenoma in 46 studies
Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Adenoma: A benign epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Potential efficacy of zileuton, a 5-LOX inhibitor, was evaluated for the reduction of pulmonary adenomas in the A/J murine model when administered via nose-only inhalation." | 7.76 | Inhalation of an ethanol-based zileuton formulation provides a reduction of pulmonary adenomas in the A/J mouse model. ( Jensen, A; Karlage, KL; Mogalian, E; Myrdal, PB, 2010) |
| "We have shown previously that naturally occurring isothiocyanates derived from cruciferous vegetables and their N-acetylcysteine conjugates inhibit lung adenoma formation induced by tobacco carcinogens in A/J mice at the post-initiation stage." | 7.73 | Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice. ( Chung, FL; Conaway, CC; Hecht, SS; McIntee, EJ; Pittman, B; Schwartz, JE; Tian, D; Wang, CX; Yang, YM, 2005) |
| "A 24 week lung adenoma bioassay using newborn mice was employed to determine the tumorigenicity of fluoranthene, a common environmental polynuclear aromatic hydrocarbon." | 7.67 | Tumorigenicity of fluoranthene in a newborn mouse lung adenoma bioassay. ( Busby, WF; Goldman, ME; Newberne, PM; Wogan, GN, 1984) |
| "Also chromosomal aberrations and micronuclei induction were evaluated in bone marrow cells." | 5.33 | Inhibition of benzo(a)pyrene induced lung adenoma by panax ginseng extract, EFLA400, in Swiss albino mice. ( Kumar, A; Kumar, M; Panwar, M; Samarth, R; Yoon, WJ, 2005) |
| "Treatment with indomethacin, another PES inhibitor, also did not reduce the pulmonary BP metabolite:DNA adduct levels." | 5.27 | Effect of aspirin and indomethacin on the formation of benzo(a)pyrene-induced pulmonary adenomas and DNA adducts in A/HeJ mice. ( Adriaenssens, PI; Anderson, MW; Boorman, GA; Eling, TE; Sivarajah, K, 1983) |
| "55 mumol) with the dose-response relationship indicating a saturation of tumor multiplicity at approximately 7 tumors/animal." | 5.27 | Dose-response relationships of the tumorigenicity of cyclopenta[cd]pyrene, benzo[a]pyrene and 6-nitrochrysene in a newborn mouse lung adenoma bioassay. ( Busby, WF; Cornelisse, J; Kellenbach, ER; Lugtenburg, J; Stevens, EK, 1988) |
| "Potential efficacy of zileuton, a 5-LOX inhibitor, was evaluated for the reduction of pulmonary adenomas in the A/J murine model when administered via nose-only inhalation." | 3.76 | Inhalation of an ethanol-based zileuton formulation provides a reduction of pulmonary adenomas in the A/J mouse model. ( Jensen, A; Karlage, KL; Mogalian, E; Myrdal, PB, 2010) |
| "We have shown previously that naturally occurring isothiocyanates derived from cruciferous vegetables and their N-acetylcysteine conjugates inhibit lung adenoma formation induced by tobacco carcinogens in A/J mice at the post-initiation stage." | 3.73 | Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice. ( Chung, FL; Conaway, CC; Hecht, SS; McIntee, EJ; Pittman, B; Schwartz, JE; Tian, D; Wang, CX; Yang, YM, 2005) |
| "We evaluated deguelin and silibinin in A/J mice treated with the tobacco-specific carcinogen benzo(a)pyrene (BP) for their ability to inhibit pulmonary adenoma formation and growth." | 3.73 | Efficacy of deguelin and silibinin on benzo(a)pyrene-induced lung tumorigenesis in A/J mice. ( Lubet, RA; Tan, Q; Wang, Y; Yan, Y; You, M, 2005) |
| " In the present study, the effects of myo-inositol and dexamethasone on benzo[a]pyrene (B[a]P)-induced pulmonary adenoma formation in female A/J mice was investigated." | 3.68 | Studies of chemopreventive effects of myo-inositol on benzo[a]pyrene-induced neoplasia of the lung and forestomach of female A/J mice. ( Estensen, RD; Wattenberg, LW, 1993) |
| "A 24 week lung adenoma bioassay using newborn mice was employed to determine the tumorigenicity of fluoranthene, a common environmental polynuclear aromatic hydrocarbon." | 3.67 | Tumorigenicity of fluoranthene in a newborn mouse lung adenoma bioassay. ( Busby, WF; Goldman, ME; Newberne, PM; Wogan, GN, 1984) |
| "The effect of Antineoplaston A10 (AA10), an amino acid derivative isolated from human urine, has been studied on pulmonary adenoma formation resulting from intragastric administration of benzo(a)pyrene(BP) to A/HeJ mice." | 3.67 | Chemoprevention by antineoplaston A10 of benzo(a)pyrene-induced pulmonary neoplasia. ( Burzynski, B; Burzynski, SR; Kampalath, BN; Liau, MC, 1987) |
| " In addition, we assessed a dose-response relationship." | 2.61 | Dietary Heterocyclic Amine Intake and Colorectal Adenoma Risk: A Systematic Review and Meta-analysis. ( Castaño, PR; Linseisen, J; Martínez Góngora, V; Matthes, KL; Rohrmann, S, 2019) |
| "Kava treatments covering the initiation stage reduced the multiplicity of lung adenomas by approximately 99%." | 1.40 | Kava blocks 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis in association with reducing O6-methylguanine DNA adduct in A/J mice. ( Balbo, S; Hecht, SS; Leitzman, P; Lu, J; Narayanapillai, SC; O'Sullivan, MG; Shaik, AA; Upadhyaya, P; Xing, C; Zhou, B, 2014) |
| "Kava treatment also inhibited the activation of nuclear factor kappaBNF-kappaB, a potential upstream mechanism of kava chemoprevention." | 1.35 | Chemopreventive effect of kava on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone plus benzo[a]pyrene-induced lung tumorigenesis in A/J mice. ( Hanson, TE; Hecht, SS; Johnson, TE; Kassie, F; Negia, M; O'Sullivan, MG; Ruvolo, PP; Upadhyaya, P; Xing, C, 2008) |
| " Both S-29606 and S-30621 were dosed via nose-only inhalation 5 days a week, for 16 weeks, whereas Zileuton was administered orally." | 1.34 | Effects of novel 5-lipoxygenase inhibitors on the incidence of pulmonary adenomas in the A/J murine model when administered via nose-only inhalation. ( Angersbach, BS; Karlage, K; Kuehl, PJ; Merrill, BA; Myrdal, PB; Wightman, PD, 2007) |
| "Also chromosomal aberrations and micronuclei induction were evaluated in bone marrow cells." | 1.33 | Inhibition of benzo(a)pyrene induced lung adenoma by panax ginseng extract, EFLA400, in Swiss albino mice. ( Kumar, A; Kumar, M; Panwar, M; Samarth, R; Yoon, WJ, 2005) |
| " A dose-response relationship for lung tumor induction by i." | 1.29 | Lung tumor induction in A/J mice by the tobacco smoke carcinogens 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and benzo[a]pyrene: a potentially useful model for evaluation of chemopreventive agents. ( Hecht, SS; Isaacs, S; Trushin, N, 1994) |
| " Dose-response studies were conducted at low doses in mouse skin by initiation-promotion and repeated application to compare its activity to that of 7,12-dimethylbenz[a]anthracene (DMBA), benzo[a]pyrene (B[a]P), DB[a,l]P-8,9-dihydrodiol and DB[a,l]P-11,12-dihydrodiol." | 1.29 | Tumor-initiating activity and carcinogenicity of dibenzo[a,l]pyrene versus 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene at low doses in mouse skin. ( Cavalieri, EL; Higginbotham, S; Johansson, SL; RamaKrishna, NV; Rogan, EG, 1993) |
| "Treatment with indomethacin, another PES inhibitor, also did not reduce the pulmonary BP metabolite:DNA adduct levels." | 1.27 | Effect of aspirin and indomethacin on the formation of benzo(a)pyrene-induced pulmonary adenomas and DNA adducts in A/HeJ mice. ( Adriaenssens, PI; Anderson, MW; Boorman, GA; Eling, TE; Sivarajah, K, 1983) |
| "Ellagic acid was the most potent antagonist of tumorigenesis since this compound is active, by i." | 1.27 | Protective effects of ellagic acid and other plant phenols on benzo[a]pyrene-induced neoplasia in mice. ( Lesca, P, 1983) |
| "55 mumol) with the dose-response relationship indicating a saturation of tumor multiplicity at approximately 7 tumors/animal." | 1.27 | Dose-response relationships of the tumorigenicity of cyclopenta[cd]pyrene, benzo[a]pyrene and 6-nitrochrysene in a newborn mouse lung adenoma bioassay. ( Busby, WF; Cornelisse, J; Kellenbach, ER; Lugtenburg, J; Stevens, EK, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (23.91) | 18.7374 |
| 1990's | 13 (28.26) | 18.2507 |
| 2000's | 17 (36.96) | 29.6817 |
| 2010's | 5 (10.87) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Martínez Góngora, V | 1 |
| Matthes, KL | 1 |
| Castaño, PR | 1 |
| Linseisen, J | 1 |
| Rohrmann, S | 1 |
| Leitzman, P | 1 |
| Narayanapillai, SC | 1 |
| Balbo, S | 1 |
| Zhou, B | 1 |
| Upadhyaya, P | 2 |
| Shaik, AA | 1 |
| O'Sullivan, MG | 2 |
| Hecht, SS | 4 |
| Lu, J | 1 |
| Xing, C | 2 |
| Tye, R | 1 |
| Stemmer, KL | 1 |
| Broussard, GW | 1 |
| Norris, MB | 1 |
| Schwindt, AR | 1 |
| Fournie, JW | 1 |
| Winn, RN | 1 |
| Kent, ML | 1 |
| Ennis, DG | 1 |
| Magesh, V | 1 |
| DurgaBhavani, K | 1 |
| Senthilnathan, P | 1 |
| Rajendran, P | 1 |
| Sakthisekaran, D | 1 |
| Johnson, TE | 1 |
| Kassie, F | 1 |
| Negia, M | 1 |
| Hanson, TE | 1 |
| Ruvolo, PP | 1 |
| Fu, H | 1 |
| He, J | 1 |
| Mei, F | 1 |
| Zhang, Q | 1 |
| Hara, Y | 2 |
| Ryota, S | 1 |
| Lubet, RA | 3 |
| Chen, R | 1 |
| Chen, DR | 1 |
| You, M | 3 |
| Bode, AM | 1 |
| Dong, Z | 1 |
| Karlage, KL | 1 |
| Mogalian, E | 1 |
| Jensen, A | 1 |
| Myrdal, PB | 2 |
| Deziel, NC | 1 |
| Strickland, PT | 1 |
| Platz, EA | 1 |
| Abubaker, S | 1 |
| Buckley, TJ | 1 |
| Hakura, A | 1 |
| Seki, Y | 1 |
| Sonoda, J | 1 |
| Hosokawa, S | 1 |
| Aoki, T | 1 |
| Suganuma, A | 1 |
| Kerns, WD | 1 |
| Tsukidate, K | 1 |
| Estensen, RD | 5 |
| Jordan, MM | 1 |
| Wiedmann, TS | 2 |
| Galbraith, AR | 3 |
| Steele, VE | 3 |
| Wattenberg, LW | 6 |
| Sinha, R | 2 |
| Kulldorff, M | 2 |
| Gunter, MJ | 1 |
| Strickland, P | 1 |
| Rothman, N | 2 |
| Peters, U | 1 |
| Cross, AJ | 1 |
| Weissfeld, JL | 1 |
| Pinsky, PF | 1 |
| Hayes, RB | 1 |
| Conaway, CC | 1 |
| Wang, CX | 1 |
| Pittman, B | 1 |
| Yang, YM | 1 |
| Schwartz, JE | 1 |
| Tian, D | 1 |
| McIntee, EJ | 1 |
| Chung, FL | 1 |
| Panwar, M | 1 |
| Samarth, R | 1 |
| Kumar, M | 1 |
| Yoon, WJ | 1 |
| Kumar, A | 1 |
| Yan, Y | 2 |
| Wang, Y | 2 |
| Tan, Q | 2 |
| Yun, TK | 3 |
| Sharma, S | 1 |
| Gao, P | 1 |
| Karlage, K | 1 |
| Kuehl, PJ | 1 |
| Angersbach, BS | 1 |
| Merrill, BA | 1 |
| Wightman, PD | 1 |
| Ritchie, KJ | 1 |
| Henderson, CJ | 1 |
| Wang, XJ | 1 |
| Vassieva, O | 1 |
| Carrie, D | 1 |
| Farmer, PB | 1 |
| Gaskell, M | 1 |
| Park, K | 1 |
| Wolf, CR | 1 |
| Adriaenssens, PI | 1 |
| Sivarajah, K | 1 |
| Boorman, GA | 1 |
| Eling, TE | 1 |
| Anderson, MW | 1 |
| Lesca, P | 1 |
| Beems, RB | 1 |
| van Beek, L | 1 |
| Busby, WF | 2 |
| Goldman, ME | 1 |
| Newberne, PM | 1 |
| Wogan, GN | 1 |
| Huang, MT | 1 |
| Lou, YR | 1 |
| Ma, W | 1 |
| Newmark, HL | 1 |
| Reuhl, KR | 1 |
| Conney, AH | 1 |
| Isaacs, S | 1 |
| Trushin, N | 1 |
| Coccia, JB | 1 |
| Kimizuka, G | 1 |
| Azuma, M | 1 |
| Ishibashi, M | 1 |
| Shinozaki, K | 1 |
| Hayashi, Y | 1 |
| Higginbotham, S | 1 |
| RamaKrishna, NV | 1 |
| Johansson, SL | 1 |
| Rogan, EG | 1 |
| Cavalieri, EL | 1 |
| Heussen, GA | 1 |
| van den Berg, JH | 1 |
| Dreef-van der Meulen, HC | 1 |
| Alink, GM | 1 |
| Culp, SJ | 1 |
| Gaylor, DW | 1 |
| Sheldon, WG | 1 |
| Goldstein, LS | 1 |
| Beland, FA | 1 |
| Lee, YS | 1 |
| Kwon, HY | 1 |
| Choi, KJ | 1 |
| Sattar, A | 1 |
| Hewer, A | 1 |
| Phillips, DH | 1 |
| Campbell, FC | 1 |
| Zimmerman, CL | 1 |
| Kelloff, GJ | 1 |
| Carlton, PS | 1 |
| Kresty, LA | 1 |
| Stoner, GD | 2 |
| Gunning, WT | 1 |
| Castonguay, A | 1 |
| Goldblatt, PJ | 1 |
| Hawkins, WE | 1 |
| Walker, WW | 1 |
| Overstreet, RM | 1 |
| Lytle, TF | 1 |
| Lytle, JS | 1 |
| Stevens, EK | 1 |
| Kellenbach, ER | 1 |
| Cornelisse, J | 1 |
| Lugtenburg, J | 1 |
| Yun, YS | 1 |
| Moon, HS | 1 |
| Oh, YR | 1 |
| Jo, SK | 1 |
| Kim, YJ | 1 |
| Kampalath, BN | 1 |
| Liau, MC | 1 |
| Burzynski, B | 1 |
| Burzynski, SR | 1 |
| Walaszek, Z | 1 |
| Hanausek-Walaszek, M | 1 |
| Webb, TE | 1 |
| Yamamoto, A | 1 |
| Hisanaga, A | 1 |
| Ishinishi, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Oral Supplementation With Curcumin on Insulin Sensitivity in Subjects With Prediabetes[NCT03917784] | Phase 4 | 142 participants (Anticipated) | Interventional | 2019-02-25 | Recruiting | ||
| The Influence of Fluticasone Inhalation on Intermediate Markers of Carcinogenesis in the Bronchial Epithelium of a High Risk Population : A Double Blind Placebo-Controlled Randomised Phase II Study[NCT00407264] | Phase 2 | 90 participants | Interventional | 2002-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for benzo(a)pyrene and Adenoma
| Article | Year |
|---|---|
Dietary Heterocyclic Amine Intake and Colorectal Adenoma Risk: A Systematic Review and Meta-analysis.
Topics: Adenoma; Adult; Aged; Amines; Benzo(a)pyrene; Colorectal Neoplasms; Diet; Female; Heterocyclic Compo | 2019 |
Epigallocatechin 3-gallate and green tea catechins: United they work, divided they fail.
Topics: Adenoma; Aerosols; Animals; Anticarcinogenic Agents; Antioxidants; Benzo(a)pyrene; Biological Availa | 2009 |
44 other studies available for benzo(a)pyrene and Adenoma
| Article | Year |
|---|---|
Kava blocks 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis in association with reducing O6-methylguanine DNA adduct in A/J mice.
Topics: Adenoma; Animal Feed; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carcinogenesis; Carcinogens; | 2014 |
Experimental carcinogenesis of the lung. II. Influence of phenols in the production of carcinoma.
Topics: Adenocarcinoma; Adenoma; Aerosols; Animals; Benzo(a)pyrene; Bronchial Neoplasms; Carcinogens; Enviro | 1967 |
Chronic Mycobacterium marinum infection acts as a tumor promoter in Japanese Medaka (Oryzias latipes).
Topics: Adenoma; Animals; Animals, Genetically Modified; Benzo(a)pyrene; Carcinogens; Carcinoma, Hepatocellu | 2009 |
In vivo protective effect of crocetin on benzo(a)pyrene-induced lung cancer in Swiss albino mice.
Topics: Adenoma; Animals; Antineoplastic Agents, Phytogenic; Benzo(a)pyrene; Carotenoids; Glycoproteins; Hex | 2009 |
Chemopreventive effect of kava on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone plus benzo[a]pyrene-induced lung tumorigenesis in A/J mice.
Topics: Adenoma; Algorithms; Animals; Antineoplastic Agents; Apoptosis; Benzo(a)pyrene; Body Weight; Cell Pr | 2008 |
Lung cancer inhibitory effect of epigallocatechin-3-gallate is dependent on its presence in a complex mixture (polyphenon E).
Topics: Adenoma; Aerosols; Animals; Anticarcinogenic Agents; Antioxidants; Benzo(a)pyrene; Biological Availa | 2009 |
Inhalation of an ethanol-based zileuton formulation provides a reduction of pulmonary adenomas in the A/J mouse model.
Topics: Adenoma; Administration, Inhalation; Animals; Benzo(a)pyrene; Chemistry, Pharmaceutical; Dosage Form | 2010 |
Comparison of standard methods for assessing dietary intake of benzo[a]pyrene.
Topics: Adenoma; Adult; Aged; Aged, 80 and over; Baltimore; Benzo(a)pyrene; Biomarkers; Case-Control Studies | 2011 |
Rapid induction of colonic adenocarcinoma in mice exposed to benzo[a]pyrene and dextran sulfate sodium.
Topics: Adenocarcinoma; Adenoma; Animals; Benzo(a)pyrene; Colon; Colonic Neoplasms; Dextran Sulfate; Drug In | 2011 |
Effect of chemopreventive agents on separate stages of progression of benzo[alpha]pyrene induced lung tumors in A/J mice.
Topics: Adenoma; Aerosols; Animals; Anti-Inflammatory Agents; Benzo(a)pyrene; Budesonide; Carcinogens; Disea | 2004 |
Dietary benzo[a]pyrene intake and risk of colorectal adenoma.
Topics: Adenoma; Benzo(a)pyrene; Case-Control Studies; Colorectal Neoplasms; Cooking; Diet; Female; Humans; | 2005 |
Meat, meat cooking methods and preservation, and risk for colorectal adenoma.
Topics: Adenoma; Aged; Benzo(a)pyrene; Carcinogens; Colorectal Neoplasms; Cooking; Diet; Female; Food Preser | 2005 |
Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice.
Topics: Acetylcysteine; Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Body Weig | 2005 |
Inhibition of benzo(a)pyrene induced lung adenoma by panax ginseng extract, EFLA400, in Swiss albino mice.
Topics: Adenoma; Animals; Animals, Newborn; Antimutagenic Agents; Antineoplastic Agents, Phytogenic; Benzo(a | 2005 |
Efficacy of deguelin and silibinin on benzo(a)pyrene-induced lung tumorigenesis in A/J mice.
Topics: Adenoma; Administration, Oral; Animals; Benzo(a)pyrene; Disease Models, Animal; Lung Neoplasms; Mice | 2005 |
Efficacy of polyphenon E, red ginseng, and rapamycin on benzo(a)pyrene-induced lung tumorigenesis in A/J mice.
Topics: Adenoma; Animals; Antibiotics, Antineoplastic; Anticarcinogenic Agents; Antineoplastic Agents; Benzo | 2006 |
The chemopreventive efficacy of inhaled oltipraz particulates in the B[a]P-induced A/J mouse lung adenoma model.
Topics: Adenoma; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Female; Inhalation; Lung Neoplasms; Mice; | 2006 |
Effects of novel 5-lipoxygenase inhibitors on the incidence of pulmonary adenomas in the A/J murine model when administered via nose-only inhalation.
Topics: Adenoma; Administration, Inhalation; Administration, Oral; Animals; Benzo(a)pyrene; Disease Models, | 2007 |
Glutathione transferase pi plays a critical role in the development of lung carcinogenesis following exposure to tobacco-related carcinogens and urethane.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adenoma; Animals; Benzo(a)pyrene; Carcinogens; D | 2007 |
Effect of aspirin and indomethacin on the formation of benzo(a)pyrene-induced pulmonary adenomas and DNA adducts in A/HeJ mice.
Topics: Adenoma; Animals; Aspirin; Benzo(a)pyrene; Benzopyrenes; Chromatography, High Pressure Liquid; Cyclo | 1983 |
Protective effects of ellagic acid and other plant phenols on benzo[a]pyrene-induced neoplasia in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Benzo(a)pyrene; Benzopyrans; Benzopyrenes; Carci | 1983 |
Modifying effect of dietary fat on benzo[a]pyrene-induced respiratory tract tumours in hamsters.
Topics: Adenocarcinoma; Adenoma; Animals; Benzo(a)pyrene; Benzopyrenes; Body Weight; Carcinogens; Carcinoma, | 1984 |
Tumorigenicity of fluoranthene in a newborn mouse lung adenoma bioassay.
Topics: Adenocarcinoma; Adenoma; Animals; Animals, Newborn; Benzo(a)pyrene; Biological Assay; Dose-Response | 1984 |
Inhibitory effects of dietary curcumin on forestomach, duodenal, and colon carcinogenesis in mice.
Topics: Adenocarcinoma; Adenoma; Adenoma, Villous; Animals; Azoxymethane; Benzo(a)pyrene; Carcinogens; Colon | 1994 |
Lung tumor induction in A/J mice by the tobacco smoke carcinogens 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and benzo[a]pyrene: a potentially useful model for evaluation of chemopreventive agents.
Topics: Adenoma; Administration, Oral; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Dose-Response Relat | 1994 |
Inhibition of carcinogen-induced pulmonary and mammary carcinogenesis by chalcone administered subsequent to carcinogen exposure.
Topics: Adenoma; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Chalcone; Female; Lung Neoplasms; Mammary | 1994 |
Co-carcinogenic effect of chrysotile and amosite asbestos with benzo(a)pyrene in the lung of hamsters.
Topics: Adenoma; Animals; Asbestos; Asbestos, Amosite; Asbestos, Serpentine; Benzo(a)pyrene; Carcinogenicity | 1993 |
Studies of chemopreventive effects of myo-inositol on benzo[a]pyrene-induced neoplasia of the lung and forestomach of female A/J mice.
Topics: Adenoma; Animals; Benzo(a)pyrene; Dexamethasone; Drug Screening Assays, Antitumor; Drug Therapy, Com | 1993 |
Tumor-initiating activity and carcinogenicity of dibenzo[a,l]pyrene versus 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene at low doses in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Carci | 1993 |
Chemopreventive effects of myo-inositol and dexamethasone on benzo[a]pyrene and 4-(methylnitrosoamino)-1-(3-pyridyl)-1-butanone-induced pulmonary carcinogenesis in female A/J mice.
Topics: Adenoma; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carcinogens; Dexamethasone; Drug Screenin | 1996 |
Carcinogenicity study of outdoor airborne particulate matter in newborn male NMRI mice.
Topics: Adenoma; Air Pollutants; Animals; Animals, Newborn; Benzo(a)pyrene; Biological Assay; Body Weight; C | 1996 |
Studies of chemopreventive effects of budenoside on benzo[a]pyrene-induced neoplasia of the lung of female A/J mice.
Topics: Adenoma; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carcinogens; Drug Screening Assays, Antit | 1997 |
A comparison of the tumors induced by coal tar and benzo[a]pyrene in a 2-year bioassay.
Topics: Adenoma; Animals; Benzo(a)pyrene; Biological Assay; Carcinoma; Coal Tar; Diet; Female; Industrial Wa | 1998 |
Saponin contents and anticarcinogenic effects of ginseng depending on types and ages in mice.
Topics: Adenoma; Animals; Antineoplastic Agents, Phytogenic; Benzo(a)pyrene; Female; Ginsenosides; Lung Neop | 1996 |
Metabolic proficiency and benzo[a]pyrene DNA adduct formation in APCMin mouse adenomas and uninvolved mucosa.
Topics: Adenoma; Animals; Benzo(a)pyrene; Carcinogens, Environmental; Colonic Neoplasms; Cytochrome P-450 CY | 1999 |
Chemoprevention of pulmonary carcinogenesis by brief exposures to aerosolized budesonide or beclomethasone dipropionate and by the combination of aerosolized budesonide and dietary myo-inositol.
Topics: Adenoma; Administration, Oral; Aerosols; Animals; Anticarcinogenic Agents; Beclomethasone; Benzo(a)p | 2000 |
Failure of dietary lyophilized strawberries to inhibit 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-and benzo[a]pyrene-induced lung tumorigenesis in strain A/J mice.
Topics: Adenoma; Animals; Antineoplastic Agents; Benzo(a)pyrene; Biological Assay; Carcinogens; Diet; Freeze | 2000 |
Strain A/J mouse lung adenoma growth patterns vary when induced by different carcinogens.
Topics: 1,2-Dimethylhydrazine; Adenoma; Aflatoxins; Animals; Benzo(a)pyrene; Carcinogens; Cell Transformatio | 1991 |
Dose-related carcinogenic effects of water-borne benzo[a]pyrene on livers of two small fish species.
Topics: Adenoma; Adenoma, Bile Duct; Animals; Benzo(a)pyrene; Liver; Liver Neoplasms, Experimental; Oryzias; | 1988 |
Dose-response relationships of the tumorigenicity of cyclopenta[cd]pyrene, benzo[a]pyrene and 6-nitrochrysene in a newborn mouse lung adenoma bioassay.
Topics: Adenoma; Animals; Animals, Newborn; Benzo(a)pyrene; Biological Assay; Carcinogens; Chrysenes; Dose-R | 1988 |
Effect of red ginseng on natural killer cell activity in mice with lung adenoma induced by urethan and benzo(a)pyrene.
Topics: Adenoma; Animals; Animals, Newborn; Benzo(a)pyrene; Cell Line; Cytotoxicity, Immunologic; Killer Cel | 1987 |
Chemoprevention by antineoplaston A10 of benzo(a)pyrene-induced pulmonary neoplasia.
Topics: Adenoma; Animals; Antineoplastic Agents; Benzeneacetamides; Benzo(a)pyrene; Body Weight; Female; Lun | 1987 |
Dietary glucarate-mediated reduction of sensitivity of murine strains to chemical carcinogenesis.
Topics: Adenoma; Animals; Benzo(a)pyrene; Diet; DNA; DNA Damage; Female; Glucaric Acid; Glucuronidase; Lung | 1986 |
Comparative study on the carcinogenicity of N-nitrosodiethylamine and benzo[a]pyrene to the lung of Syrian golden hamsters induced by intermittent instillations to the trachea.
Topics: Adenoma; Administration, Topical; Animals; Benzo(a)pyrene; Carcinoma, Squamous Cell; Cricetinae; Die | 1985 |