benzo(a)pyrene has been researched along with Adenocarcinoma of Lung in 15 studies
Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Adenocarcinoma of Lung: A carcinoma originating in the lung and the most common lung cancer type in never-smokers. Malignant cells exhibit distinct features such as glandular epithelial, or tubular morphology. Mutations in KRAS, EGFR, BRAF, and ERBB2 genes are associated with this cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "1." | 1.91 | Role and mechanism of benzo[a]pyrene in the transformation of chronic obstructive pulmonary disease into lung adenocarcinoma. ( Bai, T; Chang, F; Chen, Q; Hu, Y; Li, J; Liu, T; Wang, L; Zhang, M, 2023) |
| " (±)-anti-BPDE and B[a]P-7,8-trans-dihydrodiol, an intermediate in (±)-anti-BPDE metabolism, are toxic to A549 cells at concentrations with an IC(50) of ∼2 μM." | 1.38 | Aldo-keto reductases protect lung adenocarcinoma cells from the acute toxicity of B[a]P-7,8-trans-dihydrodiol. ( Abedin, Z; Field, J; Sen, S, 2012) |
| ") Thus, overall results suggest that nano-encapsulation of PD (NPD) increases drug bioavailability and thereby has a better chemo-preventive action against lung cancer in vivo and on A549 cells in vitro than that of PD." | 1.38 | Poly (lactide-co-glycolide) encapsulated extract of Phytolacca decandra demonstrates better intervention against induced lung adenocarcinoma in mice and on A549 cells. ( Bhadra, K; Das, J; Das, S; Khuda-Bukhsh, AR; Samadder, A, 2012) |
| "Lung cancer is the most deadly malignancy in the US." | 1.37 | Lung tumorigenesis suppressing effects of a commercial kava extract and its selected compounds in A/J mice. ( Hecht, SS; Hermanson, D; Johnson, TE; Kassie, F; Lu, J; O'Sullivan, MG; Upadhyaya, P; Wang, L; Xing, C, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 12 (80.00) | 24.3611 |
| 2020's | 3 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, L | 2 |
| Chen, Q | 2 |
| Liu, T | 1 |
| Bai, T | 1 |
| Zhang, M | 1 |
| Hu, Y | 1 |
| Li, J | 1 |
| Chang, F | 1 |
| Jimma, Y | 1 |
| Jimma, K | 1 |
| Yachi, M | 1 |
| Hakata, S | 1 |
| Habano, W | 1 |
| Ozawa, S | 1 |
| Terashima, J | 1 |
| Garg, R | 1 |
| Cooke, M | 1 |
| Benavides, F | 1 |
| Abba, MC | 1 |
| Cicchini, M | 1 |
| Feldser, DM | 1 |
| Kazanietz, MG | 1 |
| Qu, Z | 1 |
| Zhang, L | 1 |
| Hou, R | 1 |
| Ma, X | 1 |
| Yu, J | 1 |
| Zhang, W | 1 |
| Zhuang, C | 1 |
| Chen, X | 1 |
| Peng, H | 1 |
| Xiao, J | 1 |
| Guan, A | 1 |
| Xie, B | 1 |
| He, B | 1 |
| He, S | 1 |
| Ou, R | 1 |
| Wang, W | 1 |
| Ji, L | 1 |
| Gao, H | 1 |
| Zhu, Y | 1 |
| Liu, X | 1 |
| Zheng, H | 1 |
| Liu, Z | 1 |
| Wu, P | 1 |
| Lu, L | 1 |
| Bak, Y | 1 |
| Jang, HJ | 1 |
| Seo, JH | 1 |
| No, SH | 1 |
| Chae, JI | 1 |
| Hong, J | 1 |
| Yoon, DY | 1 |
| Yang, H | 1 |
| Zhang, H | 1 |
| Pan, T | 1 |
| Wang, H | 1 |
| Wang, Y | 1 |
| Barhoumi, R | 1 |
| Mouneimne, Y | 1 |
| Chapkin, RS | 1 |
| Burghardt, RC | 1 |
| Uppstad, H | 1 |
| Osnes, GH | 1 |
| Cole, KJ | 1 |
| Phillips, DH | 1 |
| Haugen, A | 1 |
| Mollerup, S | 1 |
| Paul, S | 1 |
| Bhattacharyya, SS | 1 |
| Samaddar, A | 1 |
| Boujedaini, N | 1 |
| Khuda-Bukhsh, AR | 2 |
| Johnson, TE | 1 |
| Hermanson, D | 1 |
| Kassie, F | 1 |
| Upadhyaya, P | 1 |
| O'Sullivan, MG | 1 |
| Hecht, SS | 1 |
| Lu, J | 1 |
| Xing, C | 1 |
| Lin, S | 1 |
| Lin, CJ | 1 |
| Hsieh, DP | 1 |
| Li, LA | 1 |
| Abedin, Z | 1 |
| Sen, S | 1 |
| Field, J | 1 |
| Das, J | 1 |
| Das, S | 1 |
| Samadder, A | 1 |
| Bhadra, K | 1 |
15 other studies available for benzo(a)pyrene and Adenocarcinoma of Lung
| Article | Year |
|---|---|
Role and mechanism of benzo[a]pyrene in the transformation of chronic obstructive pulmonary disease into lung adenocarcinoma.
Topics: Adenocarcinoma of Lung; Benzo(a)pyrene; Cell Proliferation; Humans; Lipopolysaccharides; Lung Neopla | 2023 |
Aryl Hydrocarbon Receptor Mediates Cell Proliferation Enhanced by Benzo[a]pyrene in Human Lung Cancer 3D Spheroids.
Topics: A549 Cells; Adenocarcinoma of Lung; Basic Helix-Loop-Helix Transcription Factors; Benzo(a)pyrene; Ce | 2019 |
PKC
Topics: Adenocarcinoma of Lung; Animals; Benzo(a)pyrene; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; C | 2020 |
Exposure to a mixture of cigarette smoke carcinogens disturbs gut microbiota and influences metabolic homeostasis in A/J mice.
Topics: Adenocarcinoma of Lung; Animals; Bacteria; Benzo(a)pyrene; Carcinogens; Dysbiosis; Feces; Female; Ga | 2021 |
Benzo(a)pyrene enhances the EMT-associated migration of lung adenocarcinoma A549 cells by upregulating Twist1.
Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Antigens, CD; Benzo(a)pyrene; Cadherins; Cell Mo | 2017 |
Camptosorus sibiricus rupr aqueous extract prevents lung tumorigenesis via dual effects against ROS and DNA damage.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Blotting, | 2018 |
Benzo[a]pyrene Alters the Expression of Genes in A549 Lung Cancer Cells and Cancer Stem Cells.
Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Benzo(a)pyrene; Cell Cycle; Cell Proliferation; | 2018 |
Benzo(a)pyrene promotes migration, invasion and metastasis of lung adenocarcinoma cells by upregulating TGIF.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Benzo(a)pyrene; Carcinogens; Cell Movement; Cell Pr | 2018 |
Effects of fatty acids on benzo[a]pyrene uptake and metabolism in human lung adenocarcinoma A549 cells.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Benzo(a)pyrene; Buthionine Sulfoximine; Cattle; Cel | 2014 |
Sex differences in susceptibility to PAHs is an intrinsic property of human lung adenocarcinoma cells.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Aryl Hydrocarbon Hydroxylases; Aryl Hydrocarbon Receptor Nuc | 2011 |
Anticancer potentials of root extract of Polygala senega against benzo[a]pyrene-induced lung cancer in mice.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Benzo(a)pyrene; Drugs, Chinese Herbal; Lung Neoplas | 2011 |
Lung tumorigenesis suppressing effects of a commercial kava extract and its selected compounds in A/J mice.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antineoplastic Agents, Phytogenic; Benzo(a)pyrene; | 2011 |
ERα phenotype, estrogen level, and benzo[a]pyrene exposure modulate tumor growth and metabolism of lung adenocarcinoma cells.
Topics: 2-Methoxyestradiol; Adenocarcinoma; Adenocarcinoma of Lung; Animals; Aryl Hydrocarbon Hydroxylases; | 2012 |
Aldo-keto reductases protect lung adenocarcinoma cells from the acute toxicity of B[a]P-7,8-trans-dihydrodiol.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adenocarcinoma; Adenocarcinoma of Lung; Alcohol | 2012 |
Poly (lactide-co-glycolide) encapsulated extract of Phytolacca decandra demonstrates better intervention against induced lung adenocarcinoma in mice and on A549 cells.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antineoplastic Agents; Arsenites; bcl-2-Associated | 2012 |