benzo(a)pyrene-7,8-dione has been researched along with Hepatocellular Carcinoma in 2 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Burczynski, ME; Harvey, RG; Penning, TM | 1 |
| Burczynski, ME; Lin, HK; Penning, TM | 1 |
2 other study(ies) available for benzo(a)pyrene-7,8-dione and Hepatocellular Carcinoma
| Article | Year |
|---|---|
Expression and characterization of four recombinant human dihydrodiol dehydrogenase isoforms: oxidation of trans-7, 8-dihydroxy-7,8-dihydrobenzo[a]pyrene to the activated o-quinone metabolite benzo[a]pyrene-7,8-dione.
Topics: Benzopyrenes; Biotransformation; Carcinoma, Hepatocellular; Catalysis; Dihydroxydihydrobenzopyrenes; DNA, Complementary; Escherichia coli; Genetic Vectors; Glycine; Humans; Isoenzymes; Kinetics; Liver; Oxidation-Reduction; Oxidoreductases; Phospholipid Ethers; Recombinant Proteins; Stereoisomerism; Tumor Cells, Cultured | 1998 |
Isoform-specific induction of a human aldo-keto reductase by polycyclic aromatic hydrocarbons (PAHs), electrophiles, and oxidative stress: implications for the alternative pathway of PAH activation catalyzed by human dihydrodiol dehydrogenase.
Topics: Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Benzopyrenes; Benzoquinones; beta-Naphthoflavone; Biotransformation; Carcinoma, Hepatocellular; Cytochrome P-450 CYP1A1; Enzyme Induction; Enzyme Inhibitors; HT29 Cells; Humans; Indicators and Reagents; Isoenzymes; Ligands; Oxidation-Reduction; Oxidative Stress; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Polychlorinated Dibenzodioxins; Polycyclic Aromatic Hydrocarbons; Receptors, Aryl Hydrocarbon; Ribonucleases; RNA, Messenger; Xenobiotics | 1999 |