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benzo(a)pyrene-7,8-dione and Hepatocellular Carcinoma

benzo(a)pyrene-7,8-dione has been researched along with Hepatocellular Carcinoma in 2 studies

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Burczynski, ME; Harvey, RG; Penning, TM1
Burczynski, ME; Lin, HK; Penning, TM1

Other Studies

2 other study(ies) available for benzo(a)pyrene-7,8-dione and Hepatocellular Carcinoma

ArticleYear
Expression and characterization of four recombinant human dihydrodiol dehydrogenase isoforms: oxidation of trans-7, 8-dihydroxy-7,8-dihydrobenzo[a]pyrene to the activated o-quinone metabolite benzo[a]pyrene-7,8-dione.
    Biochemistry, 1998, May-12, Volume: 37, Issue:19

    Topics: Benzopyrenes; Biotransformation; Carcinoma, Hepatocellular; Catalysis; Dihydroxydihydrobenzopyrenes; DNA, Complementary; Escherichia coli; Genetic Vectors; Glycine; Humans; Isoenzymes; Kinetics; Liver; Oxidation-Reduction; Oxidoreductases; Phospholipid Ethers; Recombinant Proteins; Stereoisomerism; Tumor Cells, Cultured

1998
Isoform-specific induction of a human aldo-keto reductase by polycyclic aromatic hydrocarbons (PAHs), electrophiles, and oxidative stress: implications for the alternative pathway of PAH activation catalyzed by human dihydrodiol dehydrogenase.
    Cancer research, 1999, Feb-01, Volume: 59, Issue:3

    Topics: Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Benzopyrenes; Benzoquinones; beta-Naphthoflavone; Biotransformation; Carcinoma, Hepatocellular; Cytochrome P-450 CYP1A1; Enzyme Induction; Enzyme Inhibitors; HT29 Cells; Humans; Indicators and Reagents; Isoenzymes; Ligands; Oxidation-Reduction; Oxidative Stress; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Polychlorinated Dibenzodioxins; Polycyclic Aromatic Hydrocarbons; Receptors, Aryl Hydrocarbon; Ribonucleases; RNA, Messenger; Xenobiotics

1999