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benzo(a)pyrene 7,8-dihydrodiol and Hepatocellular Carcinoma

benzo(a)pyrene 7,8-dihydrodiol has been researched along with Hepatocellular Carcinoma in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, S; Karin, M; Nguyen, N; Tamura, K; Tukey, RH1
Bouche, FB; Brandenburger, A; De Buck, SS; Muller, CP1
Burczynski, ME; Harvey, RG; Penning, TM1
Bucci, T; Fu, PP; Heflich, RH; Von Tungeln, LS; Xia, Q1

Other Studies

4 other study(ies) available for benzo(a)pyrene 7,8-dihydrodiol and Hepatocellular Carcinoma

ArticleYear
The role of the Ah receptor and p38 in benzo[a]pyrene-7,8-dihydrodiol and benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide-induced apoptosis.
    The Journal of biological chemistry, 2003, May-23, Volume: 278, Issue:21

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Apoptosis; Aryl Hydrocarbon Receptor Nuclear Translocator; bcl-X Protein; Carcinogens; Carcinoma, Hepatocellular; Caspases; Cytochrome c Group; Cytochrome P-450 CYP1A1; Dihydroxydihydrobenzopyrenes; DNA Damage; DNA-Binding Proteins; Enzyme Activation; Fibroblasts; Humans; Liver Neoplasms; Luciferases; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Receptors, Aryl Hydrocarbon; Recombinant Fusion Proteins; Transcription Factors; Transfection; Tumor Cells, Cultured

2003
Modulation of the metabolism and adverse effects of benzo[a]pyrene by a specific antibody: a novel host factor in environmental carcinogenesis?
    Carcinogenesis, 2005, Volume: 26, Issue:4

    Topics: Alkylation; Animals; Antibodies, Monoclonal; Benzo(a)pyrene; Carcinogens; Carcinoma, Hepatocellular; Cell Proliferation; Cytochrome P-450 CYP1A1; Dihydroxydihydrobenzopyrenes; DNA Adducts; Female; Humans; Liver Neoplasms; Lymphocytes; Microsomes, Liver; Rats; Rats, Wistar

2005
Expression and characterization of four recombinant human dihydrodiol dehydrogenase isoforms: oxidation of trans-7, 8-dihydroxy-7,8-dihydrobenzo[a]pyrene to the activated o-quinone metabolite benzo[a]pyrene-7,8-dione.
    Biochemistry, 1998, May-12, Volume: 37, Issue:19

    Topics: Benzopyrenes; Biotransformation; Carcinoma, Hepatocellular; Catalysis; Dihydroxydihydrobenzopyrenes; DNA, Complementary; Escherichia coli; Genetic Vectors; Glycine; Humans; Isoenzymes; Kinetics; Liver; Oxidation-Reduction; Oxidoreductases; Phospholipid Ethers; Recombinant Proteins; Stereoisomerism; Tumor Cells, Cultured

1998
Tumorigenicity and liver tumor ras-protooncogene mutations in CD-1 mice treated neonatally with 1- and 3-nitrobenzo[a]pyrene and their trans-7,8-dihydrodiol and aminobenzo[a]pyrene metabolites.
    Cancer letters, 1999, Apr-01, Volume: 137, Issue:2

    Topics: Adenoma, Liver Cell; Animals; Animals, Newborn; Benzo(a)pyrene; Benzopyrenes; Carcinogenicity Tests; Carcinoma, Hepatocellular; Chrysenes; Dihydroxydihydrobenzopyrenes; DNA Mutational Analysis; Genes, ras; Liver Neoplasms, Experimental; Male; Mice; Mutagenesis; Mutagens; Mutation

1999