Compounds > benzo(a)pyrene 7,8-dihydrodiol
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benzo(a)pyrene 7,8-dihydrodiol and Cancer of Lung

benzo(a)pyrene 7,8-dihydrodiol has been researched along with Cancer of Lung in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's2 (25.00)18.2507
2000's2 (25.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Harvey, RG; Penning, TM; Quinn, AM1
Abedin, Z; Field, J; Sen, S1
Caino, MC; Jiang, H; Kazanietz, MG; Oliva, JL; Penning, TM1
Beniashvili, DSh; Bykov, VJ; Kazanova, OI; Likhachev, AJ; Loktionova, NA; Tyndyk, ML; Yatsuk, OS; Yermilov, VB; Zabezhinski, MA1
Akagi, H; Conney, AH; Jerina, DM; Kapitulnik, J; Koreeda, M; Levin, W; Thakker, DR; Wislocki, PG; Yagi, H1
Alexandrov, K; Anttila, S; Bartsch, H; Camus, AM; Husgafvel-Pursiainen, K; Rojas, M; Vainio, H1
Kensler, TW; Seed, JL; Trush, MA1
Daniel, FB; Dixit, R; Stoner, GD; Teel, RW1

Other Studies

8 other study(ies) available for benzo(a)pyrene 7,8-dihydrodiol and Cancer of Lung

ArticleYear
Oxidation of PAH trans-dihydrodiols by human aldo-keto reductase AKR1B10.
    Chemical research in toxicology, 2008, Volume: 21, Issue:11

    Topics: Aldehyde Reductase; Aldo-Keto Reductases; Carcinogens; Carcinoma, Non-Small-Cell Lung; Cells, Cultured; Circular Dichroism; Dihydroxydihydrobenzopyrenes; Humans; Lung Neoplasms; Oxidation-Reduction; Polycyclic Aromatic Hydrocarbons; Retinaldehyde

2008
Aldo-keto reductases protect lung adenocarcinoma cells from the acute toxicity of B[a]P-7,8-trans-dihydrodiol.
    Chemical research in toxicology, 2012, Jan-13, Volume: 25, Issue:1

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adenocarcinoma; Adenocarcinoma of Lung; Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Benzo(a)pyrene; Cell Line, Tumor; Dihydroxydihydrobenzopyrenes; Epithelial Cells; Heme Oxygenase-1; Humans; Lung Neoplasms; Quinones; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; RNA, Messenger

2012
Benzo[a]pyrene-7,8-dihydrodiol promotes checkpoint activation and G2/M arrest in human bronchoalveolar carcinoma H358 cells.
    Molecular pharmacology, 2007, Volume: 71, Issue:3

    Topics: Adenocarcinoma, Bronchiolo-Alveolar; Cell Division; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 1; Cytochrome P-450 Enzyme System; Dihydroxydihydrobenzopyrenes; DNA Damage; Enzyme Activation; G2 Phase; Humans; Lung Neoplasms; Protein Kinases

2007
Biomarkers of individual susceptibility to carcinogens: application for biological monitoring.
    International archives of occupational and environmental health, 1993, Volume: 65, Issue:1 Suppl

    Topics: Adult; Age Factors; Animals; Benzo(a)pyrene; Benzopyrenes; Biomarkers; Carcinogens; Child; Dihydroxydihydrobenzopyrenes; Disease Susceptibility; DNA; DNA Repair; Environmental Monitoring; Female; Gastric Juice; Gastric Mucosa; Gastritis; Humans; Lung Neoplasms; Macaca fascicularis; Male; Methyltransferases; Middle Aged; Nitroso Compounds; O(6)-Methylguanine-DNA Methyltransferase; Rats; Smoking; Stomach Neoplasms

1993
Marked differences in the carcinogenic activity of optically pure (+)- and (-)-trans-7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene in newborn mice.
    Cancer research, 1978, Volume: 38, Issue:9

    Topics: Adenoma; Animals; Animals, Newborn; Benzopyrenes; Dihydroxydihydrobenzopyrenes; Female; Lung Neoplasms; Lymphoma; Male; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Pregnancy; Stereoisomerism

1978
Stereoselective metabolism of (-)-benzo[a]pyrene-7,8-diol by human lung microsomes and peripheral blood lymphocytes: effect of smoking.
    Carcinogenesis, 1992, Volume: 13, Issue:6

    Topics: Adolescent; Adult; Aged; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dihydroxydihydrobenzopyrenes; Female; Gene Expression Regulation, Enzymologic; Humans; Lung Neoplasms; Lymphocytes; Male; Microsomes; Middle Aged; Smoking; Stereoisomerism

1992
Reactive oxygen dependent activation of polycyclic hydrocarbons by phorbol ester-stimulated human polymorphonuclear leukocytes.
    Carcinogenesis; a comprehensive survey, 1985, Volume: 8

    Topics: Benzopyrenes; Biotransformation; Carcinogens; Dihydroxydihydrobenzopyrenes; DNA; Humans; Luminescent Measurements; Lung Neoplasms; Mutagenicity Tests; Neutrophils; Oxidation-Reduction; Oxygen; Phorbols; Polycyclic Compounds; Superoxide Dismutase; Tetradecanoylphorbol Acetate

1985
Inhibition of benzo(a)pyrene and benzo(a)pyrene-trans-7,8-diol metabolism and DNA binding in mouse lung explants by ellagic acid.
    Cancer research, 1985, Volume: 45, Issue:7

    Topics: Animals; Benzo(a)pyrene; Benzopyrans; Benzopyrenes; Dihydroxydihydrobenzopyrenes; DNA; Ellagic Acid; Lung; Lung Neoplasms; Male; Mice; Mice, Inbred Strains

1985