benzimidazole has been researched along with Obesity in 4 studies
1H-benzimidazole : The 1H-tautomer of benzimidazole.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Compound 18c demonstrates in vivo CB1 antagonist efficacy (CB1 agonist induced hypothermia model) and is orally bioavailable in rat." | 1.36 | Identification and hit-to-lead optimization of a novel class of CB1 antagonists. ( Baker, J; Cowley, P; Edwards, D; Ho, KK; Jokiel, P; Letourneau, JJ; McAleer, L; Ohlmeyer, MH; Olson, J; Riviello, CM; Swanson, RN; Ward, N; Webb, ML; Yang, J, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Letourneau, JJ | 1 |
| Jokiel, P | 1 |
| Olson, J | 1 |
| Riviello, CM | 1 |
| Ho, KK | 1 |
| McAleer, L | 1 |
| Yang, J | 1 |
| Swanson, RN | 1 |
| Baker, J | 1 |
| Cowley, P | 1 |
| Edwards, D | 1 |
| Ward, N | 1 |
| Ohlmeyer, MH | 1 |
| Webb, ML | 1 |
| Lee, K | 1 |
| Goo, JI | 1 |
| Jung, HY | 1 |
| Kim, M | 1 |
| Boovanahalli, SK | 1 |
| Park, HR | 1 |
| Kim, MO | 1 |
| Kim, DH | 1 |
| Lee, HS | 1 |
| Choi, Y | 1 |
| Tamura, Y | 1 |
| Hayashi, K | 1 |
| Omori, N | 1 |
| Nishiura, Y | 1 |
| Watanabe, K | 1 |
| Tanaka, N | 1 |
| Fujioka, M | 1 |
| Kouyama, N | 1 |
| Yukimasa, A | 1 |
| Tanaka, Y | 1 |
| Chiba, T | 1 |
| Tanioka, H | 1 |
| Nambu, H | 1 |
| Yukioka, H | 1 |
| Sato, H | 1 |
| Okuno, T | 1 |
| Carpenter, AJ | 1 |
| Al-Barazanji, KA | 1 |
| Barvian, KK | 1 |
| Bishop, MJ | 1 |
| Britt, CS | 1 |
| Cooper, JP | 1 |
| Goetz, AS | 1 |
| Grizzle, MK | 1 |
| Hertzog, DL | 1 |
| Ignar, DM | 1 |
| Morgan, RO | 1 |
| Peckham, GE | 1 |
| Speake, JD | 1 |
| Swain, WR | 1 |
4 other studies available for benzimidazole and Obesity
| Article | Year |
|---|---|
Identification and hit-to-lead optimization of a novel class of CB1 antagonists.
Topics: Animals; Benzimidazoles; Humans; Hypothermia; Indoles; Male; Mice; Microsomes, Liver; Obesity; Rats; | 2010 |
Discovery of a novel series of benzimidazole derivatives as diacylglycerol acyltransferase inhibitors.
Topics: Animals; Benzimidazoles; Diacylglycerol O-Acyltransferase; Dose-Response Relationship, Drug; Drug Di | 2012 |
Identification of a novel benzimidazole derivative as a highly potent NPY Y5 receptor antagonist with an anti-obesity profile.
Topics: Administration, Oral; Animals; Anti-Obesity Agents; Benzimidazoles; Cytochrome P-450 Enzyme Inhibito | 2013 |
Novel benzimidazole-based MCH R1 antagonists.
Topics: Animals; Benzimidazoles; Biological Availability; Body Composition; Dose-Response Relationship, Drug | 2006 |