benzimidazole has been researched along with Edema in 8 studies
1H-benzimidazole : The 1H-tautomer of benzimidazole.
Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The compounds were evaluated for their anti-inflammatory activity in carrageenan induced rat paw edema model taking rofecoxib and indomethacin as standard drugs." | 3.85 | Synthesis of methanesulphonamido-benzimidazole derivatives as gastro-sparing antiinflammatory agents with antioxidant effect. ( Bali, A; Chaudhari, BB; Sharma, R, 2017) |
| " All the compounds were found to cause less gastric ulceration than the standard drug diclofenac." | 3.83 | Synthesis and Pharmacological Evaluation of Tetrazolobenzimidazoles as Novel Anti-inflammatory Agents. ( Kale, MA; Kuberkar, SV; Nawale, RB; Peharkar, MR, 2016) |
| " The newly synthesized compounds were screened for analgesic and anti-inflammatory activities on acetic acid induced writhing in mice and carrageenan induced paw oedema in rats." | 3.76 | In-vivo analgesic and anti-inflammatory activities of newly synthesized benzimidazole derivatives. ( Achar, KC; Hosamani, KM; Seetharamareddy, HR, 2010) |
| " Derivatives 4a, 4b and 4c exhibited moderate to good anti-inflammatory and analgesic activity in carrageenan-induced rat paw edema and acetic acid-induced writhing in mice, respectively, with low ulcerogenicity compared with the standard drug indomethacin." | 3.76 | Synthesis and pharmacological evaluation of novel 5-substituted-1-(phenylsulfonyl)-2-methylbenzimidazole derivatives as anti-inflammatory and analgesic agents. ( Gaba, M; Gaba, P; Sharma, V; Singh, D; Singh, S, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Maghraby, MT | 1 |
| Abou-Ghadir, OMF | 1 |
| Abdel-Moty, SG | 2 |
| Ali, AY | 1 |
| Salem, OIA | 1 |
| Sharma, R | 1 |
| Bali, A | 1 |
| Chaudhari, BB | 1 |
| Mohammed, AF | 1 |
| Hussein, MA | 1 |
| Abdel-Alim, AA | 1 |
| Bansal, Y | 1 |
| Kaur, M | 1 |
| Silakari, O | 1 |
| Kale, MA | 1 |
| Nawale, RB | 1 |
| Peharkar, MR | 1 |
| Kuberkar, SV | 1 |
| El-Nezhawy, AO | 1 |
| Gaballah, ST | 1 |
| Radwan, MA | 1 |
| Baiuomy, AR | 1 |
| Abdel-Salam, OM | 1 |
| Achar, KC | 1 |
| Hosamani, KM | 1 |
| Seetharamareddy, HR | 1 |
| Gaba, M | 1 |
| Singh, D | 1 |
| Singh, S | 1 |
| Sharma, V | 1 |
| Gaba, P | 1 |
8 other studies available for benzimidazole and Edema
| Article | Year |
|---|---|
Novel class of benzimidazole-thiazole hybrids: The privileged scaffolds of potent anti-inflammatory activity with dual inhibition of cyclooxygenase and 15-lipoxygenase enzymes.
Topics: Animals; Anti-Inflammatory Agents; Arachidonate 15-Lipoxygenase; Benzimidazoles; Carrageenan; Cycloo | 2020 |
Synthesis of methanesulphonamido-benzimidazole derivatives as gastro-sparing antiinflammatory agents with antioxidant effect.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Benzimidazoles; C | 2017 |
Design, synthesis and molecular docking of some new 1,2,4-triazolobenzimidazol-3-yl acetohydrazide derivatives with anti-inflammatory-analgesic activities.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzimidazoles; Drug Design; Edema; Male; Mice; Molec | 2013 |
Benzimidazole--ibuprofen/mesalamine conjugates: potential candidates for multifactorial diseases.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Benzimidazoles; Edema; Ibup | 2015 |
Synthesis and Pharmacological Evaluation of Tetrazolobenzimidazoles as Novel Anti-inflammatory Agents.
Topics: Animals; Anti-Inflammatory Agents; Benzimidazoles; Carrageenan; Diclofenac; Disease Models, Animal; | 2016 |
Structure-based design of benzimidazole sugar conjugates: synthesis, SAR and in vivo anti-inflammatory and analgesic activities.
Topics: Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Antidepressive Agents; Benzimidazoles; Carb | 2009 |
In-vivo analgesic and anti-inflammatory activities of newly synthesized benzimidazole derivatives.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzimidazoles; Carrageen | 2010 |
Synthesis and pharmacological evaluation of novel 5-substituted-1-(phenylsulfonyl)-2-methylbenzimidazole derivatives as anti-inflammatory and analgesic agents.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzimidazoles; Carrageenan; Edema; Male; Mice; Rats; | 2010 |