benzimidazole has been researched along with Disease Models, Animal in 16 studies
1H-benzimidazole : The 1H-tautomer of benzimidazole.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " All the compounds were found to cause less gastric ulceration than the standard drug diclofenac." | 3.83 | Synthesis and Pharmacological Evaluation of Tetrazolobenzimidazoles as Novel Anti-inflammatory Agents. ( Kale, MA; Kuberkar, SV; Nawale, RB; Peharkar, MR, 2016) |
| "Currently, the treatment of gout mainly includes two basic methods: reducing uric acid and alleviating inflammation." | 1.56 | Development of novel NLRP3-XOD dual inhibitors for the treatment of gout. ( Ha, EH; Hu, Q; Li, H; Li, Z; Pang, J; Tian, S; Wang, W; Zhou, M, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 12 (75.00) | 24.3611 |
| 2020's | 3 (18.75) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, W | 1 |
| Pang, J | 1 |
| Ha, EH | 1 |
| Zhou, M | 1 |
| Li, Z | 1 |
| Tian, S | 1 |
| Li, H | 1 |
| Hu, Q | 2 |
| Cardoso Santos, C | 1 |
| Meuser Batista, M | 1 |
| Inam Ullah, A | 1 |
| Rama Krishna Reddy, T | 1 |
| Soeiro, MNC | 1 |
| Liu, S | 1 |
| Liu, D | 1 |
| Shen, R | 1 |
| Li, D | 1 |
| Yan, Y | 1 |
| Sun, J | 1 |
| Zhang, F | 1 |
| Wan, H | 1 |
| Dong, P | 1 |
| Feng, J | 1 |
| Zhang, R | 1 |
| Li, J | 1 |
| Zhang, L | 1 |
| Tao, W | 1 |
| Abbhi, V | 1 |
| Saini, L | 1 |
| Mishra, S | 1 |
| Sethi, G | 1 |
| Kumar, AP | 1 |
| Piplani, P | 1 |
| Farahat, AA | 1 |
| Ismail, MA | 1 |
| Kumar, A | 1 |
| Wenzler, T | 1 |
| Brun, R | 1 |
| Paul, A | 1 |
| Wilson, WD | 1 |
| Boykin, DW | 1 |
| Mayoka, G | 1 |
| Keiser, J | 1 |
| Häberli, C | 1 |
| Chibale, K | 1 |
| Sinclair, DA | 1 |
| Guarente, L | 1 |
| Knudson, SE | 2 |
| Awasthi, D | 2 |
| Kumar, K | 2 |
| Carreau, A | 1 |
| Goullieux, L | 1 |
| Lagrange, S | 1 |
| Vermet, H | 1 |
| Ojima, I | 2 |
| Slayden, RA | 2 |
| Datar, PA | 1 |
| Limaye, SA | 1 |
| Evans, CW | 1 |
| Atkins, C | 1 |
| Pathak, A | 1 |
| Gilbert, BE | 1 |
| Noah, JW | 1 |
| Kale, MA | 1 |
| Nawale, RB | 1 |
| Peharkar, MR | 1 |
| Kuberkar, SV | 1 |
| Dang, Q | 1 |
| Kasibhatla, SR | 1 |
| Xiao, W | 1 |
| Liu, Y | 1 |
| Dare, J | 1 |
| Taplin, F | 1 |
| Reddy, KR | 1 |
| Scarlato, GR | 1 |
| Gibson, T | 1 |
| van Poelje, PD | 1 |
| Potter, SC | 1 |
| Erion, MD | 1 |
| Garrity-Ryan, LK | 1 |
| Kim, OK | 1 |
| Balada-Llasat, JM | 1 |
| Bartlett, VJ | 1 |
| Verma, AK | 1 |
| Fisher, ML | 1 |
| Castillo, C | 1 |
| Songsungthong, W | 1 |
| Tanaka, SK | 1 |
| Levy, SB | 1 |
| Mecsas, J | 1 |
| Alekshun, MN | 1 |
| Díaz-Chiguer, DL | 1 |
| Márquez-Navarro, A | 1 |
| Nogueda-Torres, B | 1 |
| de la Luz León-Ávila, G | 1 |
| Pérez-Villanueva, J | 1 |
| Hernández-Campos, A | 1 |
| Castillo, R | 1 |
| Ambrosio, JR | 1 |
| Nieto-Meneses, R | 1 |
| Yépez-Mulia, L | 1 |
| Hernández-Luis, F | 1 |
| Le, HT | 1 |
| Lemaire, IB | 1 |
| Gilbert, AK | 1 |
| Jolicoeur, F | 1 |
| Yang, L | 1 |
| Leduc, N | 1 |
| Lemaire, S | 1 |
1 review available for benzimidazole and Disease Models, Animal
| Article | Year |
|---|---|
Small-molecule allosteric activators of sirtuins.
Topics: Allosteric Regulation; Animals; Benzimidazoles; Disease Models, Animal; Humans; Inflammation; Molecu | 2014 |
15 other studies available for benzimidazole and Disease Models, Animal
| Article | Year |
|---|---|
Development of novel NLRP3-XOD dual inhibitors for the treatment of gout.
Topics: Animals; Benzimidazoles; Benzoxazoles; Cell Line; Disease Models, Animal; Gout; Humans; Hyperuricemi | 2020 |
Drug screening using shape-based virtual screening and
Topics: Animals; Antiprotozoal Agents; Benzimidazoles; Cells, Cultured; Disease Models, Animal; Drug Evaluat | 2021 |
Discovery of a novel RORγ antagonist with skin-restricted exposure for topical treatment of mild to moderate psoriasis.
Topics: Administration, Topical; Animals; Benzimidazoles; Binding Sites; Disease Models, Animal; Drug Evalua | 2021 |
Design and synthesis of benzimidazole-based Rho kinase inhibitors for the treatment of glaucoma.
Topics: Animals; Antihypertensive Agents; Benzimidazoles; Disease Models, Animal; Dose-Response Relationship | 2017 |
Indole and Benzimidazole Bichalcophenes: Synthesis, DNA Binding and Antiparasitic Activity.
Topics: Animals; Benzimidazoles; Cell Survival; Disease Models, Animal; Indoles; Mice; Parasitic Sensitivity | 2018 |
Structure-Activity Relationship and in Vitro Absorption, Distribution, Metabolism, Excretion, and Toxicity (ADMET) Studies of N-aryl 3-Trifluoromethyl Pyrido[1,2- a]benzimidazoles That Are Efficacious in a Mouse Model of Schistosomiasis.
Topics: Animals; Benzimidazoles; Disease Models, Animal; Humans; Male; Mice; Mice, Inbred BALB C; Schistosom | 2019 |
A trisubstituted benzimidazole cell division inhibitor with efficacy against Mycobacterium tuberculosis.
Topics: Animals; Antitubercular Agents; Bacterial Proteins; Benzimidazoles; Cell Division; Cytoskeletal Prot | 2014 |
In vitro-in vivo activity relationship of substituted benzimidazole cell division inhibitors with activity against Mycobacterium tuberculosis.
Topics: Animals; Antitubercular Agents; Benzimidazoles; Cell Division; Disease Models, Animal; Drug Combinat | 2014 |
Design and Synthesis of Mannich bases as Benzimidazole Derivatives as Analgesic Agents.
Topics: Acetic Acid; Analgesics; Animals; Benzimidazoles; Diclofenac; Disease Models, Animal; Drug Evaluatio | 2015 |
Benzimidazole analogs inhibit respiratory syncytial virus G protein function.
Topics: Animals; Antiviral Agents; Benzimidazoles; Cell Line; Disease Models, Animal; Drug Resistance, Viral | 2015 |
Synthesis and Pharmacological Evaluation of Tetrazolobenzimidazoles as Novel Anti-inflammatory Agents.
Topics: Animals; Anti-Inflammatory Agents; Benzimidazoles; Carrageenan; Diclofenac; Disease Models, Animal; | 2016 |
Fructose-1,6-bisphosphatase Inhibitors. 2. Design, synthesis, and structure-activity relationship of a series of phosphonic acid containing benzimidazoles that function as 5'-adenosinemonophosphate (AMP) mimics.
Topics: Adenosine Monophosphate; Animals; Benzimidazoles; Diabetes Mellitus, Type 2; Disease Models, Animal; | 2010 |
Small molecule inhibitors of LcrF, a Yersinia pseudotuberculosis transcription factor, attenuate virulence and limit infection in a murine pneumonia model.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Benzimidazoles; Cell Line; Disease Models, Anima | 2010 |
In vitro and in vivo trypanocidal activity of some benzimidazole derivatives against two strains of Trypanosoma cruzi.
Topics: Animals; Antiprotozoal Agents; Benzimidazoles; Cell Survival; Chagas Disease; Chlorocebus aethiops; | 2012 |
Histogranin-like antinociceptive and anti-inflammatory derivatives of o-phenylenediamine and benzimidazole.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzimidazoles; Cyclooxygenase 2; Dinoprostone; Disea | 2004 |