benzimidazole has been researched along with Diabetes Mellitus, Type 2 in 3 studies
1H-benzimidazole : The 1H-tautomer of benzimidazole.
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Type 2 diabetes mellitus is a complex metabolic disorder requiring polypharmacology approaches for effective treatment." | 1.51 | Towards multi-target antidiabetic agents: Discovery of biphenyl-benzimidazole conjugates as AMPK activators. ( Babkov, DA; Babkova, VA; Borisov, AV; Borodkin, GS; Brigadirova, AA; Kolodina, AA; Litvinov, RA; Morkovnik, AS; Sochnev, VS; Sokolova, EV; Spasov, AA; Zhukowskaya, ON, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Babkov, DA | 1 |
| Zhukowskaya, ON | 1 |
| Borisov, AV | 1 |
| Babkova, VA | 1 |
| Sokolova, EV | 1 |
| Brigadirova, AA | 1 |
| Litvinov, RA | 1 |
| Kolodina, AA | 1 |
| Morkovnik, AS | 1 |
| Sochnev, VS | 1 |
| Borodkin, GS | 1 |
| Spasov, AA | 1 |
| Herbst, L | 1 |
| Goebel, M | 1 |
| Bandholtz, S | 1 |
| Gust, R | 1 |
| Kintscher, U | 1 |
| Dang, Q | 1 |
| Kasibhatla, SR | 1 |
| Xiao, W | 1 |
| Liu, Y | 1 |
| Dare, J | 1 |
| Taplin, F | 1 |
| Reddy, KR | 1 |
| Scarlato, GR | 1 |
| Gibson, T | 1 |
| van Poelje, PD | 1 |
| Potter, SC | 1 |
| Erion, MD | 1 |
3 other studies available for benzimidazole and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Towards multi-target antidiabetic agents: Discovery of biphenyl-benzimidazole conjugates as AMPK activators.
Topics: AMP-Activated Protein Kinases; Animals; Benzimidazoles; Biphenyl Compounds; Cattle; Diabetes Mellitu | 2019 |
Characterization of telmisartan-derived PPARγ agonists: importance of moiety shift from position 6 to 5 on potency, efficacy and cofactor recruitment.
Topics: 3T3-L1 Cells; Animals; Benzimidazoles; Benzoates; Benzofurans; Chlorocebus aethiops; COS Cells; Diab | 2012 |
Fructose-1,6-bisphosphatase Inhibitors. 2. Design, synthesis, and structure-activity relationship of a series of phosphonic acid containing benzimidazoles that function as 5'-adenosinemonophosphate (AMP) mimics.
Topics: Adenosine Monophosphate; Animals; Benzimidazoles; Diabetes Mellitus, Type 2; Disease Models, Animal; | 2010 |