Page last updated: 2024-11-06

benzimidazole and Cytomegalovirus

benzimidazole has been researched along with Cytomegalovirus in 6 studies

1H-benzimidazole : The 1H-tautomer of benzimidazole.

Cytomegalovirus: A genus of the family HERPESVIRIDAE, subfamily BETAHERPESVIRINAE, infecting the salivary glands, liver, spleen, lungs, eyes, and other organs, in which they produce characteristically enlarged cells with intranuclear inclusions. Infection with Cytomegalovirus is also seen as an opportunistic infection in AIDS.

Research Excerpts

ExcerptRelevanceReference
"Benzimidazole D-ribonucleosides inhibit DNA packaging during human cytomegalovirus (HCMV) replication."7.74Putative functional domains of human cytomegalovirus pUL56 involved in dimerization and benzimidazole D-ribonucleoside activity. ( Alain, S; Bouaziz, S; Champier, G; Couvreux, A; Denis, F; Hantz, S; Mazeron, MC; Rametti, A, 2008)
"The benzimidazole D-ribonucleosides TCRB and BDCRB are potent and selective inhibitors of human cytomegalovirus (HCMV) replication."7.72Role of a mutation in human cytomegalovirus gene UL104 in resistance to benzimidazole ribonucleosides. ( Drach, JC; Komazin, G; Townsend, LB, 2004)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (83.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ourahmane, A1
Sauer, A1
Nixon, DE1
Murphy, C1
Mondello, M1
Douglass Chiu, E1
Siegmund, S1
Wang, JB1
McVoy, MA1
Champier, G1
Couvreux, A1
Hantz, S1
Rametti, A1
Mazeron, MC1
Bouaziz, S1
Denis, F1
Alain, S1
Williams, SL1
Hartline, CB1
Kushner, NL1
Harden, EA1
Bidanset, DJ1
Drach, JC4
Townsend, LB4
Underwood, MR1
Biron, KK1
Kern, ER1
Komazin, G1
Dittmer, A1
Fischer, A1
Bogner, E2
Hwang, JS1
Kregler, O1
Schilf, R1
Bannert, N1

Other Studies

6 other studies available for benzimidazole and Cytomegalovirus

ArticleYear
A Guinea pig cytomegalovirus resistant to the DNA maturation inhibitor BDCRB.
    Antiviral research, 2018, Volume: 154

    Topics: Animals; Antiviral Agents; Benzimidazoles; Cells, Cultured; Cytomegalovirus; Cytomegalovirus Infecti

2018
Putative functional domains of human cytomegalovirus pUL56 involved in dimerization and benzimidazole D-ribonucleoside activity.
    Antiviral therapy, 2008, Volume: 13, Issue:5

    Topics: Amino Acid Sequence; Benzimidazoles; Cells, Cultured; Cytomegalovirus; Dimerization; DNA, Viral; Fib

2008
In vitro activities of benzimidazole D- and L-ribonucleosides against herpesviruses.
    Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:7

    Topics: Antiviral Agents; Benzimidazoles; Cytomegalovirus; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpe

2003
Role of a mutation in human cytomegalovirus gene UL104 in resistance to benzimidazole ribonucleosides.
    Journal of virology, 2004, Volume: 78, Issue:2

    Topics: Amino Acid Sequence; Antiviral Agents; Benzimidazoles; Capsid Proteins; Cells, Cultured; Cytomegalov

2004
Interaction of the putative human cytomegalovirus portal protein pUL104 with the large terminase subunit pUL56 and its inhibition by benzimidazole-D-ribonucleosides.
    Journal of virology, 2005, Volume: 79, Issue:23

    Topics: Benzimidazoles; Capsid Proteins; Cell Culture Techniques; Cytomegalovirus; Endodeoxyribonucleases; E

2005
Identification of acetylated, tetrahalogenated benzimidazole D-ribonucleosides with enhanced activity against human cytomegalovirus.
    Journal of virology, 2007, Volume: 81, Issue:21

    Topics: Acylation; Animals; Antiviral Agents; Benzimidazoles; Cytomegalovirus; Drug Evaluation, Preclinical;

2007